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The use of cannabis as a treatment for epilepsy in adult patients: are side effects a limitation of use? / Lady Diana Ladino Malagón
Título : The use of cannabis as a treatment for epilepsy in adult patients: are side effects a limitation of use? Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Autor asociado al HPTU Fecha de publicación : 2020 Títulos uniformes : Journal of Clinical Neurophysiology Idioma : Inglés (eng) Palabras clave : Cannabis CBD Epilepsy Treatment Adults Resumen : Marijuana is the dried leaves, stems, and flowers of a 1- to 5-m weed originating from Central Asia. The most common varieties are Cannabis sativa and Cannabis indica. It is usually inhaled as smoke but can also be used as a vapor, taken by mouth as a spray, ingested in tea or as butter in baked goods, or in capsule form and used as an oil. Cannabis has been widely used to treat many medical conditions such as multiple sclerosis symptoms, mood disorders, pain, sleep disorders, and seizures among others. Preclinical and clinical studies have been done over the past decade, among them there are few randomized placebo-controlled trials. In the last few years, Cannabis has been proposed as a potential therapy for patients with drug-resistant epilepsy. This review analyzes the best information about the use of cannabis in adult patients, reviewing aspects of efficacy and safety. Mención de responsabilidad : Jose F Téllez-Zenteno, Lady D Ladino, Lizbeth Hernández-Ronquillo Referencia : J Clin Neurophysiol. 2020;37(1):9–14. DOI (Digital Object Identifier) : 10.1097/WNP.0000000000000637 PMID : 31895185 En línea : https://journals.lww.com/clinicalneurophys/Abstract/2020/01000/The_Use_of_Cannab [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis The use of cannabis as a treatment for epilepsy in adult patients: are side effects a limitation of use? [documento electrónico] / Lady Diana Ladino Malagón, Autor asociado al HPTU . - 2020.
Obra : Journal of Clinical Neurophysiology
Idioma : Inglés (eng)
Palabras clave : Cannabis CBD Epilepsy Treatment Adults Resumen : Marijuana is the dried leaves, stems, and flowers of a 1- to 5-m weed originating from Central Asia. The most common varieties are Cannabis sativa and Cannabis indica. It is usually inhaled as smoke but can also be used as a vapor, taken by mouth as a spray, ingested in tea or as butter in baked goods, or in capsule form and used as an oil. Cannabis has been widely used to treat many medical conditions such as multiple sclerosis symptoms, mood disorders, pain, sleep disorders, and seizures among others. Preclinical and clinical studies have been done over the past decade, among them there are few randomized placebo-controlled trials. In the last few years, Cannabis has been proposed as a potential therapy for patients with drug-resistant epilepsy. This review analyzes the best information about the use of cannabis in adult patients, reviewing aspects of efficacy and safety. Mención de responsabilidad : Jose F Téllez-Zenteno, Lady D Ladino, Lizbeth Hernández-Ronquillo Referencia : J Clin Neurophysiol. 2020;37(1):9–14. DOI (Digital Object Identifier) : 10.1097/WNP.0000000000000637 PMID : 31895185 En línea : https://journals.lww.com/clinicalneurophys/Abstract/2020/01000/The_Use_of_Cannab [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001305 AC-2020-009 Archivo digital Producción Científica Artículos científicos Disponible
Título : Medicinal marijuana for epilepsy: a case series study Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Autor asociado al HPTU Fecha de publicación : 2014 Títulos uniformes : Canadian Journal of Neurological Sciences Dimensiones : Idioma : Inglés (eng) Palabras clave : anticonvulsant cannabis cannabinoids medicinal marijuana seizures Resumen : Objective: To describe the social, clinical and use-patterns characteristics of medicinal marijuana use among patients with epilepsy (PWEs). Methods: Eighteen PWEs with prescriptions for medicinal marijuana from a Canadian adult-epilepsy clinic were included in this study. Results: Eighteen patients had a prescription of medicinal marijuana from a total population of 800 PWEs in our center (2.2%). Mean age of patients was 30±7.4 (19-50) years. Twelve (67%) patients were males. Eleven (61%) patients had drug resistant epilepsy. Eleven (61%) patients suffered a psychiatric comorbidity and reported the use of illicit substances or heavy alcohol or tobacco consumption. Only two (11%) patients were married; the rest of patients (89%) were single or divorced. The drug use pattern was similar among patients. All patients asked for marijuana permission in the epilepsy clinic. Most (83%) had a previous history of marijuana smoking, with a mean of 6.6±3 (1-15) years. The mean consumption dose was 2.05±1.8 (0.5-8) grams per day. Ten (56%) patients reported withdrawal seizure exacerbation when they stopped the marijuana. Only two patients (11%) reported side effects, and all patients found medicinal marijuana very helpful for seizure control and improvement of mood disorder. Conclusions: PWEs using medicinal marijuana have a common profile. They are usually young single men with drug-resistant epilepsy and psychiatric comorbidity. Most used marijuana before formal prescription and all believe the drug was effective on their seizure control. Because of the concurrent use of other antiseizure medications, it is complex to estimate the actual effect of marijuana. Mención de responsabilidad : Lady Diana Ladino, Lizbeth Hernández-Ronquillo, José Francisco Téllez-Zenteno Referencia : Can J Neurol Sci. 2014 Nov;41(6):753-8 DOI (Digital Object Identifier) : 10.1017/cjn.2014.37 PMID : 25377755 En línea : https://www.cambridge.org/core/journals/canadian-journal-of-neurological-science [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Medicinal marijuana for epilepsy: a case series study [documento electrónico] / Lady Diana Ladino Malagón, Autor asociado al HPTU . - 2014 . - ; PDF.
Obra : Canadian Journal of Neurological Sciences
Idioma : Inglés (eng)
Palabras clave : anticonvulsant cannabis cannabinoids medicinal marijuana seizures Resumen : Objective: To describe the social, clinical and use-patterns characteristics of medicinal marijuana use among patients with epilepsy (PWEs). Methods: Eighteen PWEs with prescriptions for medicinal marijuana from a Canadian adult-epilepsy clinic were included in this study. Results: Eighteen patients had a prescription of medicinal marijuana from a total population of 800 PWEs in our center (2.2%). Mean age of patients was 30±7.4 (19-50) years. Twelve (67%) patients were males. Eleven (61%) patients had drug resistant epilepsy. Eleven (61%) patients suffered a psychiatric comorbidity and reported the use of illicit substances or heavy alcohol or tobacco consumption. Only two (11%) patients were married; the rest of patients (89%) were single or divorced. The drug use pattern was similar among patients. All patients asked for marijuana permission in the epilepsy clinic. Most (83%) had a previous history of marijuana smoking, with a mean of 6.6±3 (1-15) years. The mean consumption dose was 2.05±1.8 (0.5-8) grams per day. Ten (56%) patients reported withdrawal seizure exacerbation when they stopped the marijuana. Only two patients (11%) reported side effects, and all patients found medicinal marijuana very helpful for seizure control and improvement of mood disorder. Conclusions: PWEs using medicinal marijuana have a common profile. They are usually young single men with drug-resistant epilepsy and psychiatric comorbidity. Most used marijuana before formal prescription and all believe the drug was effective on their seizure control. Because of the concurrent use of other antiseizure medications, it is complex to estimate the actual effect of marijuana. Mención de responsabilidad : Lady Diana Ladino, Lizbeth Hernández-Ronquillo, José Francisco Téllez-Zenteno Referencia : Can J Neurol Sci. 2014 Nov;41(6):753-8 DOI (Digital Object Identifier) : 10.1017/cjn.2014.37 PMID : 25377755 En línea : https://www.cambridge.org/core/journals/canadian-journal-of-neurological-science [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000419 AC-2014-085 Archivo digital Producción Científica Artículos científicos Disponible