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Enlace permanente de la investigaciónClinical characteristics of children with SARS-CoV-2 infection in a hospital in Latin America / Laura Fernanda Niño Serna ; Eliana López Barón ; Isabel Cristina Maya Ángel ; Carolina Tamayo Múnera
Título : Clinical characteristics of children with SARS-CoV-2 infection in a hospital in Latin America Tipo de documento : documento electrónico Autores : Laura Fernanda Niño Serna, ; Eliana López Barón, ; Isabel Cristina Maya Ángel, ; Carolina Tamayo Múnera, Fecha de publicación : 2022 Títulos uniformes : Frontiers in Pediatrics Idioma : Inglés (eng) Palabras clave : pediatrics comorbidity inpatients pediatric intensive care unit Latin America COVID-19 Resumen : Objective: COVID-19 infections have shown a different behavior in children than in adults. The objective of this study was to describe the clinical characteristics and severity of SARS-CoV-2 infection in pediatric patients seen at a reference hospital in Colombia. Method: A descriptive, observational study in patients under the age of 18 years with a positive test for SARS-CoV-2 infection (RT-PCR or antigen) between April 2020 and March 2021. Multiple variables were studied, including demographic data, clinical characteristics, lab measurements, treatments administered, intensive care unit admission, and mortality. Results: A total of 361 patients were included of whom 196 (54%) were males. The median age was 3 years. Of all the patients, 65 (18%) were asymptomatic. The majority of patients had no comorbidities (n = 225, 76%). In those who were symptomatic (n = 296, 82%), the most frequent complaints were fever (n = 178, 60%), nasal congestion (n = 164, 55%) and cough (n = 149, 50%). Chest x-rays were normal in 73 patients (50%). When abnormalities were found, interstitial (29%) and alveolar (12%) patterns were the most prevalent. One hundred and fifty-seven children (53%) required general ward hospitalization, and 24 patients (8%) required pediatric intensive care admission. The global mortality was 0.8% (3 patients). Conclusions: The majority of cases were asymptomatic or mild. However, a significant percentage of patients required general ward admission, and some even required intensive care. The main symptom of COVID-19 infections in newborns was apnea. A second COVID-19 RT-PCR may be necessary to detect infections in critically ill patients with a high clinical suspicion of the disease if an initial test was negative. Mención de responsabilidad : Laura F. Niño-Serna, Eliana López-Barón, Isabel Cristina Maya Ángel and Carolina Tamayo-Múnera Referencia : Front Pediatr. 2022 Jun 9;10:921880. DOI (Digital Object Identifier) : 10.3389/fped.2022.921880 PMID : 35757135 Derechos de uso : CC BY En línea : https://www.frontiersin.org/articles/10.3389/fped.2022.921880/full Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6032 Clinical characteristics of children with SARS-CoV-2 infection in a hospital in Latin America [documento electrónico] / Laura Fernanda Niño Serna, ; Eliana López Barón, ; Isabel Cristina Maya Ángel, ; Carolina Tamayo Múnera, . - 2022.
Obra : Frontiers in Pediatrics
Idioma : Inglés (eng)
Palabras clave : pediatrics comorbidity inpatients pediatric intensive care unit Latin America COVID-19 Resumen : Objective: COVID-19 infections have shown a different behavior in children than in adults. The objective of this study was to describe the clinical characteristics and severity of SARS-CoV-2 infection in pediatric patients seen at a reference hospital in Colombia. Method: A descriptive, observational study in patients under the age of 18 years with a positive test for SARS-CoV-2 infection (RT-PCR or antigen) between April 2020 and March 2021. Multiple variables were studied, including demographic data, clinical characteristics, lab measurements, treatments administered, intensive care unit admission, and mortality. Results: A total of 361 patients were included of whom 196 (54%) were males. The median age was 3 years. Of all the patients, 65 (18%) were asymptomatic. The majority of patients had no comorbidities (n = 225, 76%). In those who were symptomatic (n = 296, 82%), the most frequent complaints were fever (n = 178, 60%), nasal congestion (n = 164, 55%) and cough (n = 149, 50%). Chest x-rays were normal in 73 patients (50%). When abnormalities were found, interstitial (29%) and alveolar (12%) patterns were the most prevalent. One hundred and fifty-seven children (53%) required general ward hospitalization, and 24 patients (8%) required pediatric intensive care admission. The global mortality was 0.8% (3 patients). Conclusions: The majority of cases were asymptomatic or mild. However, a significant percentage of patients required general ward admission, and some even required intensive care. The main symptom of COVID-19 infections in newborns was apnea. A second COVID-19 RT-PCR may be necessary to detect infections in critically ill patients with a high clinical suspicion of the disease if an initial test was negative. Mención de responsabilidad : Laura F. Niño-Serna, Eliana López-Barón, Isabel Cristina Maya Ángel and Carolina Tamayo-Múnera Referencia : Front Pediatr. 2022 Jun 9;10:921880. DOI (Digital Object Identifier) : 10.3389/fped.2022.921880 PMID : 35757135 Derechos de uso : CC BY En línea : https://www.frontiersin.org/articles/10.3389/fped.2022.921880/full Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6032 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001874 AC-2022-039 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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Título : Clinical differentiation of inflammatory bowel disease (IBD) in Latin America and the Caribbean Tipo de documento : documento electrónico Autores : Fabián Juliao Baños, Fecha de publicación : 2022 Títulos uniformes : Medicine (Baltimore) Idioma : Inglés (eng) Palabras clave : Crohn disease epidemiology inflammatory bowel disease Latin America ulcerative colitis Resumen : The aim of the present study was to describe the epidemiological and clinical characteristics of inflammatory bowel disease (IBD), including medical and surgical treatments, in several countries in Latin America and the Caribbean. IBD is recognized as a global health problem because its incidence and prevalence have increased significantly over the last few years. This multicenter retrospective cohort study included 4714 patients with IBD diagnosed from 9 countries in Latin America and the Caribbean: Colombia, Cuba, Dominican Republic, Ecuador, Mexico, Peru, Puerto Rico, Uruguay, and Venezuela. Crohn disease (CD) was more frequent in Puerto Rico (71.9%), the Dominican Republic (61.0%), and Peru (53.1%). Ulcerative colitis was more frequent in Colombia (78.6%), Venezuela (78.2%), Mexico (75.5%), Cuba (69.9%), Ecuador (64.1%), and Uruguay (60.9%). The following clinical characteristics were more frequent in the Caribbean: penetrating behavior in CD, steroid dependence, steroid resistance, intolerance to thiopurines, extraintestinal manifestations, surgeries, hospitalizations due to IBD, and family history of IBD. The factors associated with the use of biological therapy were pancolitis in ulcerative colitis, penetrating behavior in CD, steroid resistance and dependence, presence of extraintestinal manifestations, and the need for surgery. This study from Latin America and the Caribbean demonstrated the different epidemiological and clinical characteristics of IBD. Mención de responsabilidad : Yamamoto-Furusho, Jesús K. MD, PhD, MSc; Parra-Holguín, Norma N. MD; Juliao-Baños, Fabián MD; Puentes, Fabián MD; López, Rocio MD; Bosques-Padilla, Francisco MD; Torres, Esther A. MD; Nieves-Jimenéz, Humberto MD; Veitia-Velásquez, Guillermo R. MD; Jara-Alba, Maria L. MD; Bautista, Sócrates MD; Piñol-Jimenez, Felipe N. MD; Salgado-Rosado, Pablo MD; Villa-Ovalle, Keyla C. MD; Abreu-Martinez, Yudelka A. MD; Borges, Zunilda MD; Davila-Bedoya, Santiago MD; Otoya-Moreno, Guillermo MD; Iadé-Vergara, Beatriz MD Referencia : Medicine (Baltimore). 2022 Jan 21;101(3):e28624. DOI (Digital Object Identifier) : 10.1097/MD.0000000000028624 PMID : 35060539 Derechos de uso : CC BY En línea : https://journals.lww.com/md-journal/Fulltext/2022/01210/Clinical_differentiation [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6097 Clinical differentiation of inflammatory bowel disease (IBD) in Latin America and the Caribbean [documento electrónico] / Fabián Juliao Baños, . - 2022.
Obra : Medicine (Baltimore)
Idioma : Inglés (eng)
Palabras clave : Crohn disease epidemiology inflammatory bowel disease Latin America ulcerative colitis Resumen : The aim of the present study was to describe the epidemiological and clinical characteristics of inflammatory bowel disease (IBD), including medical and surgical treatments, in several countries in Latin America and the Caribbean. IBD is recognized as a global health problem because its incidence and prevalence have increased significantly over the last few years. This multicenter retrospective cohort study included 4714 patients with IBD diagnosed from 9 countries in Latin America and the Caribbean: Colombia, Cuba, Dominican Republic, Ecuador, Mexico, Peru, Puerto Rico, Uruguay, and Venezuela. Crohn disease (CD) was more frequent in Puerto Rico (71.9%), the Dominican Republic (61.0%), and Peru (53.1%). Ulcerative colitis was more frequent in Colombia (78.6%), Venezuela (78.2%), Mexico (75.5%), Cuba (69.9%), Ecuador (64.1%), and Uruguay (60.9%). The following clinical characteristics were more frequent in the Caribbean: penetrating behavior in CD, steroid dependence, steroid resistance, intolerance to thiopurines, extraintestinal manifestations, surgeries, hospitalizations due to IBD, and family history of IBD. The factors associated with the use of biological therapy were pancolitis in ulcerative colitis, penetrating behavior in CD, steroid resistance and dependence, presence of extraintestinal manifestations, and the need for surgery. This study from Latin America and the Caribbean demonstrated the different epidemiological and clinical characteristics of IBD. Mención de responsabilidad : Yamamoto-Furusho, Jesús K. MD, PhD, MSc; Parra-Holguín, Norma N. MD; Juliao-Baños, Fabián MD; Puentes, Fabián MD; López, Rocio MD; Bosques-Padilla, Francisco MD; Torres, Esther A. MD; Nieves-Jimenéz, Humberto MD; Veitia-Velásquez, Guillermo R. MD; Jara-Alba, Maria L. MD; Bautista, Sócrates MD; Piñol-Jimenez, Felipe N. MD; Salgado-Rosado, Pablo MD; Villa-Ovalle, Keyla C. MD; Abreu-Martinez, Yudelka A. MD; Borges, Zunilda MD; Davila-Bedoya, Santiago MD; Otoya-Moreno, Guillermo MD; Iadé-Vergara, Beatriz MD Referencia : Medicine (Baltimore). 2022 Jan 21;101(3):e28624. DOI (Digital Object Identifier) : 10.1097/MD.0000000000028624 PMID : 35060539 Derechos de uso : CC BY En línea : https://journals.lww.com/md-journal/Fulltext/2022/01210/Clinical_differentiation [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6097 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001945 AC-2022-106 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2022-106.pdfAdobe Acrobat PDF
Título : Impact of COVID-19 infection on patients with cancer: experience in a Latin American country: the ACHOCC-19 study Tipo de documento : documento electrónico Autores : Alicia Quiroga Echeverri, Fecha de publicación : 2021 Títulos uniformes : The Oncologist Idioma : Inglés (eng) Palabras clave : Cancer Covid-19 Latin America mortality survival Resumen : Introduction: The ACHOCC-19 study was performed to characterize COVID-19 infection in our oncological population. Methodology: Analytical cohort study of patients with cancer and COVID-19 infection in Colombia. From April 1 to October 31, 2020. Demographic and clinical variables related to cancer and COVID-19 infection were collected. The primary outcome was 30-day mortality from all causes. The association between the outcome and the prognostic variables was analyzed using logistic regression models and survival analysis with Cox regression. Results: 742 patients were included. 72% > 51 years. The most prevalent neoplasms were breast (132 [17,77%]), colorectal (92 12,34%), and prostate (81 [10,9%]). 220 (29,6%) patients were asymptomatic and 96 (26,3%) died. In the bivariate descriptive analysis, higher mortality in patients > 70 years, lung cancer, ≥2 comorbidities, former smokers, receiving antibiotics, corticosteroids, and anticoagulants, residents of rural areas, low socioeconomic status, and increased acute phase reactants. In the logistic regression analysis, higher mortality with ECOG 3 OR 28,67 (8,2-99,6), ECOG 4 OR 20,89 (3,36-129,7), two complications from COVID-19 OR 5,3 (1,50-18,1), and cancer in progression OR 02,08 (1,01-4,27). In the Cox regression analysis, the statistically significant HRs were metastatic disease HR 1,58 (1,16 - 2,16), cancer in progression HR 1,08 (1,24 - 2,61) vs partial response HR 0,31 (0,11 - 0,88), use of steroids HR 1,44 (1,01 - 2,06) and antibiotics HR 2,11 (1,47 - 2,95). Interpretations: In our study, cancer patients have higher mortality due to COVID-19 infection if they have active cancer, metastatic or progressive cancer, ECOG status >2 and low socioeconomic status. Implications for practice: Our findings raise the need to carefully evaluate patients with metastatic cancer, in progression, and with impaired ECOG to define the relevance of cancer treatment during the pandemic, consider the risk/benefit of the interventions, and establish clear and complete communication with the patients and their families about the risk of complications. There is also the importance of offering additional support to patients with low income and residence in rural areas so that they can have more support during cancer treatment. Mención de responsabilidad : Aylen Vanessa Ospina, Ricardo Bruges, William Mantilla, Iván Triana, Pedro Ramos, Sandra Aruachan, Alicia Quiroga, Isabel Munevar, Juan Ortiz, Néstor Llinás, Paola Pinilla, Henry Vargas, Henry Idrobo, Andrea Russi, Ray Manneh Kopp, Giovanna Rivas, Héctor González, Daniel Santa, Jesús Insuasty, Laura Bernal, Jorge Otero, Carlos Vargas, Javier Pacheco, Carmen Alcalá, Paola Jiménez, Milton Lombana, Fernando Contreras, Javier Segovia, Luis Pino, José Lobatón, Manuel González, Javier Cuello, Juliana Bogoya, Angela Barrero, Gilberto de Lima Lopes Jr Referencia : Oncologist. 2021 Oct;26(10):e1761-e1773. DOI (Digital Object Identifier) : 10.1002/onco.13861 PMID : 34132449 En línea : https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13861 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5791 Impact of COVID-19 infection on patients with cancer: experience in a Latin American country: the ACHOCC-19 study [documento electrónico] / Alicia Quiroga Echeverri, . - 2021.
Obra : The Oncologist
Idioma : Inglés (eng)
Palabras clave : Cancer Covid-19 Latin America mortality survival Resumen : Introduction: The ACHOCC-19 study was performed to characterize COVID-19 infection in our oncological population. Methodology: Analytical cohort study of patients with cancer and COVID-19 infection in Colombia. From April 1 to October 31, 2020. Demographic and clinical variables related to cancer and COVID-19 infection were collected. The primary outcome was 30-day mortality from all causes. The association between the outcome and the prognostic variables was analyzed using logistic regression models and survival analysis with Cox regression. Results: 742 patients were included. 72% > 51 years. The most prevalent neoplasms were breast (132 [17,77%]), colorectal (92 12,34%), and prostate (81 [10,9%]). 220 (29,6%) patients were asymptomatic and 96 (26,3%) died. In the bivariate descriptive analysis, higher mortality in patients > 70 years, lung cancer, ≥2 comorbidities, former smokers, receiving antibiotics, corticosteroids, and anticoagulants, residents of rural areas, low socioeconomic status, and increased acute phase reactants. In the logistic regression analysis, higher mortality with ECOG 3 OR 28,67 (8,2-99,6), ECOG 4 OR 20,89 (3,36-129,7), two complications from COVID-19 OR 5,3 (1,50-18,1), and cancer in progression OR 02,08 (1,01-4,27). In the Cox regression analysis, the statistically significant HRs were metastatic disease HR 1,58 (1,16 - 2,16), cancer in progression HR 1,08 (1,24 - 2,61) vs partial response HR 0,31 (0,11 - 0,88), use of steroids HR 1,44 (1,01 - 2,06) and antibiotics HR 2,11 (1,47 - 2,95). Interpretations: In our study, cancer patients have higher mortality due to COVID-19 infection if they have active cancer, metastatic or progressive cancer, ECOG status >2 and low socioeconomic status. Implications for practice: Our findings raise the need to carefully evaluate patients with metastatic cancer, in progression, and with impaired ECOG to define the relevance of cancer treatment during the pandemic, consider the risk/benefit of the interventions, and establish clear and complete communication with the patients and their families about the risk of complications. There is also the importance of offering additional support to patients with low income and residence in rural areas so that they can have more support during cancer treatment. Mención de responsabilidad : Aylen Vanessa Ospina, Ricardo Bruges, William Mantilla, Iván Triana, Pedro Ramos, Sandra Aruachan, Alicia Quiroga, Isabel Munevar, Juan Ortiz, Néstor Llinás, Paola Pinilla, Henry Vargas, Henry Idrobo, Andrea Russi, Ray Manneh Kopp, Giovanna Rivas, Héctor González, Daniel Santa, Jesús Insuasty, Laura Bernal, Jorge Otero, Carlos Vargas, Javier Pacheco, Carmen Alcalá, Paola Jiménez, Milton Lombana, Fernando Contreras, Javier Segovia, Luis Pino, José Lobatón, Manuel González, Javier Cuello, Juliana Bogoya, Angela Barrero, Gilberto de Lima Lopes Jr Referencia : Oncologist. 2021 Oct;26(10):e1761-e1773. DOI (Digital Object Identifier) : 10.1002/onco.13861 PMID : 34132449 En línea : https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13861 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5791 Reserva
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Título : Therapeutic plasmapheresis for the treatment of thyrotoxicosis: A retrospective multi-center study Tipo de documento : documento electrónico Autores : Carlos Esteban Builes Montaño, ; Carolina Prieto Saldarriaga, ; Clara María Arango Toro, Fecha de publicación : 2021 Títulos uniformes : Journal of Clinical Apheresis Idioma : Inglés (eng) Palabras clave : anti-thyroid agents hyperthyroidism Latin America plasmapheresis thyrotoxicosis Resumen : Background and aims: Thyroid storm and severe thyrotoxicosis remain among the most frequent endocrine emergencies, and first-line hyperthyroidism treatment is not always an option. Since the first report in 1970, plasmapheresis is a second-line treatment for severe or otherwise untreatable thyrotoxicosis when rapid euthyroidism is desired. Methods: We present a retrospective study of the experience in treating thyrotoxicosis with plasmapheresis between 2012 and 2020 in two specialized centers in Colombia. We register the demographic and clinical characteristic and compare the thyroid hormones and other biochemical measurements before and after treatment. Results: Data from 19 patients was obtained, 58% female with a median age of 35 years (IQR 23.5), and most of them with Graves' disease. The most frequent indication for plasmapheresis was thyroid storm. A median of 4 (IQR 2) sessions lead to a significant reduction in FT4 (P .0001) and TT3 (P Mención de responsabilidad : Carlos E. Builes-Montaño,Luis A. Rodriguez-Arrieta,Alejandro Román-González,Carolina Prieto-Saldarriaga,Jose C. Alvarez-Payares,Carlos A. Builes-Barrera,Clara M. Arango-Toro Referencia : J Clin Apher. 2021 Oct;36(5):759-765. DOI (Digital Object Identifier) : 10.1002/jca.21927 PMID : 34273178 En línea : https://onlinelibrary.wiley.com/doi/10.1002/jca.21927 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5818 Therapeutic plasmapheresis for the treatment of thyrotoxicosis: A retrospective multi-center study [documento electrónico] / Carlos Esteban Builes Montaño, ; Carolina Prieto Saldarriaga, ; Clara María Arango Toro, . - 2021.
Obra : Journal of Clinical Apheresis
Idioma : Inglés (eng)
Palabras clave : anti-thyroid agents hyperthyroidism Latin America plasmapheresis thyrotoxicosis Resumen : Background and aims: Thyroid storm and severe thyrotoxicosis remain among the most frequent endocrine emergencies, and first-line hyperthyroidism treatment is not always an option. Since the first report in 1970, plasmapheresis is a second-line treatment for severe or otherwise untreatable thyrotoxicosis when rapid euthyroidism is desired. Methods: We present a retrospective study of the experience in treating thyrotoxicosis with plasmapheresis between 2012 and 2020 in two specialized centers in Colombia. We register the demographic and clinical characteristic and compare the thyroid hormones and other biochemical measurements before and after treatment. Results: Data from 19 patients was obtained, 58% female with a median age of 35 years (IQR 23.5), and most of them with Graves' disease. The most frequent indication for plasmapheresis was thyroid storm. A median of 4 (IQR 2) sessions lead to a significant reduction in FT4 (P .0001) and TT3 (P Mención de responsabilidad : Carlos E. Builes-Montaño,Luis A. Rodriguez-Arrieta,Alejandro Román-González,Carolina Prieto-Saldarriaga,Jose C. Alvarez-Payares,Carlos A. Builes-Barrera,Clara M. Arango-Toro Referencia : J Clin Apher. 2021 Oct;36(5):759-765. DOI (Digital Object Identifier) : 10.1002/jca.21927 PMID : 34273178 En línea : https://onlinelibrary.wiley.com/doi/10.1002/jca.21927 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5818 Reserva
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Título : Different outcomes for transplant-eligible newly diagnosed multiple myeloma patients in Latin America according to the public versus private management: a GELAMM study Tipo de documento : documento electrónico Autores : Kenny Mauricio Gálvez Cárdenas, Fecha de publicación : 2020 Títulos uniformes : Leukemia and Lymphoma Idioma : Inglés (eng) Palabras clave : Multiple myeloma Latin America autologous stem cell transplantation proteasome inhibitor Resumen : The aim of this study was to describe clinical and survival characteristics of transplant-eligible multiple myeloma (MM) patients in Latin America (LA), with a special focus on differences between public and private healthcare facilities. We included 1293 patients diagnosed between 2010 and 2018. A great disparity in outcomes and survival between both groups was observed. Late diagnosis and low access to adequate frontline therapy and ASCT in public institutions probably explain these differences. Patients treated with novel drug induction protocols, followed by autologous stem cell transplantation (ASCT) and maintenance, have similar overall survival compared to that published internationally. Mención de responsabilidad : Camila Peña , Eloisa Riva , Natalia Schutz , Luz Tarín-Arzaga , Humberto Martínez-Cordero , Virginia Bove , Rocío Osorio , Mauricio Chandía , Cecilia Beltrán , Javier Schulz , Daniela Cardemil , Carolina Contreras , Carmen Gloria Vergara , Javiera Donoso , Marcela Espinoza , Gabriel La Rocca , Hernán López-Vidal , Pilar León , Christine Rojas Hopkins , Pablo Soto , Sandra Aranda , Vivianne Torres , Macarena Roa , Paola Ochoa , Patricio Jose Duarte , Guillermina Remaggi , Sebastián Yantorno , Ariel Corzo , Soledad Zabaljauregui , Claudia Shanley , Sergio Lopresti , Sergio Orlando , Verónica Verri , Luis Quiroga , Carlos García , Vanesa Fernández , Jhoanna Ramirez , Alicia Molina , María Pacheco , Alex Mite , Inés Reyes , Brenner Sabando , Francisca Ramírez , Claudia Sossa , Virginia Abello , Henry Idrobo , Kenny Mauricio Galvez Cardenas , Domingo Saavedra , Guillermo Quintero , Raimundo Gazitúa , Lina Gaviria , Rigoberto Gomez , Mónica Osuna , Alicia Henao-Uribe , Omar Cantú-Martínez , Referencia : Leuk Lymphoma. 2020 Dec;61(13):3112-3119. DOI (Digital Object Identifier) : 10.1080/10428194.2020.1804558 PMID : 32844699 En línea : https://www.tandfonline.com/doi/full/10.1080/10428194.2020.1804558 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5127 Different outcomes for transplant-eligible newly diagnosed multiple myeloma patients in Latin America according to the public versus private management: a GELAMM study [documento electrónico] / Kenny Mauricio Gálvez Cárdenas, . - 2020.
Obra : Leukemia and Lymphoma
Idioma : Inglés (eng)
Palabras clave : Multiple myeloma Latin America autologous stem cell transplantation proteasome inhibitor Resumen : The aim of this study was to describe clinical and survival characteristics of transplant-eligible multiple myeloma (MM) patients in Latin America (LA), with a special focus on differences between public and private healthcare facilities. We included 1293 patients diagnosed between 2010 and 2018. A great disparity in outcomes and survival between both groups was observed. Late diagnosis and low access to adequate frontline therapy and ASCT in public institutions probably explain these differences. Patients treated with novel drug induction protocols, followed by autologous stem cell transplantation (ASCT) and maintenance, have similar overall survival compared to that published internationally. Mención de responsabilidad : Camila Peña , Eloisa Riva , Natalia Schutz , Luz Tarín-Arzaga , Humberto Martínez-Cordero , Virginia Bove , Rocío Osorio , Mauricio Chandía , Cecilia Beltrán , Javier Schulz , Daniela Cardemil , Carolina Contreras , Carmen Gloria Vergara , Javiera Donoso , Marcela Espinoza , Gabriel La Rocca , Hernán López-Vidal , Pilar León , Christine Rojas Hopkins , Pablo Soto , Sandra Aranda , Vivianne Torres , Macarena Roa , Paola Ochoa , Patricio Jose Duarte , Guillermina Remaggi , Sebastián Yantorno , Ariel Corzo , Soledad Zabaljauregui , Claudia Shanley , Sergio Lopresti , Sergio Orlando , Verónica Verri , Luis Quiroga , Carlos García , Vanesa Fernández , Jhoanna Ramirez , Alicia Molina , María Pacheco , Alex Mite , Inés Reyes , Brenner Sabando , Francisca Ramírez , Claudia Sossa , Virginia Abello , Henry Idrobo , Kenny Mauricio Galvez Cardenas , Domingo Saavedra , Guillermo Quintero , Raimundo Gazitúa , Lina Gaviria , Rigoberto Gomez , Mónica Osuna , Alicia Henao-Uribe , Omar Cantú-Martínez , Referencia : Leuk Lymphoma. 2020 Dec;61(13):3112-3119. DOI (Digital Object Identifier) : 10.1080/10428194.2020.1804558 PMID : 32844699 En línea : https://www.tandfonline.com/doi/full/10.1080/10428194.2020.1804558 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5127 Reserva
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