Inicio
Resultado de la búsqueda
6 búsqueda de la palabra clave 'Pneumonia'
Clasificado(s) por (Año de edición descendente) Refinar búsqueda Genera el flujo rss de la búsqueda
Enlace permanente de la investigación
Etiology and the challenge of diagnostic testing of community-acquired pneumonia in children and adolescents / Andrea Victoria Restrepo Gouzy ; Mónica Rosa Trujillo Honeysberg
Título : Etiology and the challenge of diagnostic testing of community-acquired pneumonia in children and adolescents Tipo de documento : documento electrónico Autores : Andrea Victoria Restrepo Gouzy, Autor asociado al HPTU ; Mónica Rosa Trujillo Honeysberg, Autor asociado al HPTU Fecha de publicación : 2022 Títulos uniformes : BMC Pediatrics Idioma : Inglés (eng) Palabras clave : Pneumonia Diagnosis Etiology Multiplex PCR Serology Induced sputum Nasopharyngeal swab Urine antigen Children Resumen : Background: Pneumonia is the leading cause of mortality in pediatric population. The etiology of pneumonia in this population is variable and changes according to age and disease severity and where the study is conducted. Our aim was to determine the etiology of community-acquired pneumonia (CAP) in children aged 1 month to 17 years admitted to 13 Colombian hospitals. Methods: Prospective cohort study. Hospitalized children with radiologically confirmed CAP and ≤ 15 days of symptoms were included and followed together with a control group. Induced sputum (IS) was submitted for stains and cultures for pyogenic bacteria and Mycobacterium tuberculosis, and multiplex PCR (mPCR) for bacteria and viruses; urinary antigens for pneumococcus and Legionella pneumophila; nasopharyngeal swabs for viruses, and paired serology for atypical bacteria and viruses. Additional cultures were taken at the discretion of primary care pediatricians. Results: Among 525 children with CAP, 71.6% had non-severe pneumonia; 24.8% severe and 3.6% very severe pneumonia, and no fatal cases. At least one microorganism was identified in 84% of children and 61% were of mixed etiology; 72% had at least one respiratory virus, 28% pyogenic bacteria and 21% atypical bacteria. Respiratory syncytial virus, Parainfluenza, Rhinovirus, Influenza, Mycoplasma pneumoniae, Adenovirus and Streptococcus pneumoniae were the most common etiologies of CAP. Respiratory syncytial virus was more frequent in children under 2 years and in severe pneumonia. Tuberculosis was diagnosed in 2.3% of children. IS was the most useful specimen to identify the etiology (33.6%), and blood cultures were positive in 3.6%. The concordance between all available diagnostic tests was low. A high percentage of healthy children were colonized by S. pneumoniae and Haemophilus influenzae, or were infected by Parainfluenza, Rhinovirus, Influenza and Adenovirus. Conclusions: Respiratory viruses are the most frequent etiology of CAP in children and adolescents, in particular in those under 5 years. This study shows the challenges in making an etiologic diagnosis of CAP in pediatric population because of the poor concordance between tests and the high percentage of multiple microorganisms in healthy children. IS is useful for CAP diagnosis in pediatric population. Mención de responsabilidad : Zulma Vanessa Rueda, Yudy Aguilar, María Angélica Maya, Lucelly López, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Mónica Trujillo, Catalina Arango, Ángela Rocio Copete, Cristian Vera, Margarita Rosa Giraldo, Mariana Herrera & Lázaro A. Vélez Referencia : BMC Pediatr. 2022 Mar 31;22(1):169. DOI (Digital Object Identifier) : 10.1186/s12887-022-03235-z PMID : 35361166 Derechos de uso : CC BY En línea : https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03235-z Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Etiology and the challenge of diagnostic testing of community-acquired pneumonia in children and adolescents [documento electrónico] / Andrea Victoria Restrepo Gouzy, Autor asociado al HPTU ; Mónica Rosa Trujillo Honeysberg, Autor asociado al HPTU . - 2022.
Obra : BMC Pediatrics
Idioma : Inglés (eng)
Palabras clave : Pneumonia Diagnosis Etiology Multiplex PCR Serology Induced sputum Nasopharyngeal swab Urine antigen Children Resumen : Background: Pneumonia is the leading cause of mortality in pediatric population. The etiology of pneumonia in this population is variable and changes according to age and disease severity and where the study is conducted. Our aim was to determine the etiology of community-acquired pneumonia (CAP) in children aged 1 month to 17 years admitted to 13 Colombian hospitals. Methods: Prospective cohort study. Hospitalized children with radiologically confirmed CAP and ≤ 15 days of symptoms were included and followed together with a control group. Induced sputum (IS) was submitted for stains and cultures for pyogenic bacteria and Mycobacterium tuberculosis, and multiplex PCR (mPCR) for bacteria and viruses; urinary antigens for pneumococcus and Legionella pneumophila; nasopharyngeal swabs for viruses, and paired serology for atypical bacteria and viruses. Additional cultures were taken at the discretion of primary care pediatricians. Results: Among 525 children with CAP, 71.6% had non-severe pneumonia; 24.8% severe and 3.6% very severe pneumonia, and no fatal cases. At least one microorganism was identified in 84% of children and 61% were of mixed etiology; 72% had at least one respiratory virus, 28% pyogenic bacteria and 21% atypical bacteria. Respiratory syncytial virus, Parainfluenza, Rhinovirus, Influenza, Mycoplasma pneumoniae, Adenovirus and Streptococcus pneumoniae were the most common etiologies of CAP. Respiratory syncytial virus was more frequent in children under 2 years and in severe pneumonia. Tuberculosis was diagnosed in 2.3% of children. IS was the most useful specimen to identify the etiology (33.6%), and blood cultures were positive in 3.6%. The concordance between all available diagnostic tests was low. A high percentage of healthy children were colonized by S. pneumoniae and Haemophilus influenzae, or were infected by Parainfluenza, Rhinovirus, Influenza and Adenovirus. Conclusions: Respiratory viruses are the most frequent etiology of CAP in children and adolescents, in particular in those under 5 years. This study shows the challenges in making an etiologic diagnosis of CAP in pediatric population because of the poor concordance between tests and the high percentage of multiple microorganisms in healthy children. IS is useful for CAP diagnosis in pediatric population. Mención de responsabilidad : Zulma Vanessa Rueda, Yudy Aguilar, María Angélica Maya, Lucelly López, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Mónica Trujillo, Catalina Arango, Ángela Rocio Copete, Cristian Vera, Margarita Rosa Giraldo, Mariana Herrera & Lázaro A. Vélez Referencia : BMC Pediatr. 2022 Mar 31;22(1):169. DOI (Digital Object Identifier) : 10.1186/s12887-022-03235-z PMID : 35361166 Derechos de uso : CC BY En línea : https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03235-z Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
Reservar este documento
Ejemplares (1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001870 AC-2022-035 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
AC-2022-035Adobe Acrobat PDF Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents / Andrea Victoria Restrepo Gouzy ; Mónica Rosa Trujillo Honeysberg
Título : Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents Tipo de documento : documento electrónico Autores : Andrea Victoria Restrepo Gouzy, Autor asociado al HPTU ; Mónica Rosa Trujillo Honeysberg, Autor asociado al HPTU Fecha de publicación : 2022 Títulos uniformes : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Induced sputum adolescents children diagnosis etiology pneumonia Resumen : Objectives: This study aimed to evaluate the utility of induced sputum (IS) for the diagnosis of community-acquired pneumonia (CAP) in pediatric population. Methods: This cross-sectional study included pediatric population aged between 1 month and 17 years who were hospitalized with a diagnosis of CAP in 13 hospitals in Colombia, in whom an IS sample was obtained. Gram staining, aerobic bacterial and mycobacterial culture tests, and polymerase chain reaction (PCR) for 6 atypical bacteria and 15 respiratory viruses were performed. We evaluated the quality of IS samples. Results: IS samples were collected in 516 of 525 children included in this study. The median age was 32 months, 38.6% were younger than 2 years, and 40.9% were between 2 and 5 years. Two patients had transient hypoxemia during the procedure. The quality of the IS obtained was good in 48.4% and intermediate in 24.5%. Identification of a respiratory pathogen was achieved with an IS sample (with Gram staining, culture test, and PCR) in 372 of 516 children with CAP. Conclusion: Our study shows that IS is an adequate sample for the diagnosis of CAP in pediatric population that required hospitalization. The procedure was safe, well tolerated, and with better diagnostic yields compared with the rest of the samples obtained. Mención de responsabilidad : Zulma Vanessa Rueda, Marcela Bermúdez, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Luisa Fernanda Carmona, Catalina Arango, Jose Luis Albarracín, Lucelly López, Yudy Aguilar, María Angélica Maya, Mónica Trujillo, Ángela Rocio Copete, Cristian Vera, Mariana Herrera, Margarita Rosa Giraldo, Gloria Isabel Niño-Cruz, Lázaro A Vélez Referencia : Int J Infect Dis. 2022 Jan 19;116:348-354. DOI (Digital Object Identifier) : 10.1016/j.ijid.2022.01.026 PMID : 35063681 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(22)00025-X Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents [documento electrónico] / Andrea Victoria Restrepo Gouzy, Autor asociado al HPTU ; Mónica Rosa Trujillo Honeysberg, Autor asociado al HPTU . - 2022.
Obra : International Journal of Infectious Diseases
Idioma : Inglés (eng)
Palabras clave : Induced sputum adolescents children diagnosis etiology pneumonia Resumen : Objectives: This study aimed to evaluate the utility of induced sputum (IS) for the diagnosis of community-acquired pneumonia (CAP) in pediatric population. Methods: This cross-sectional study included pediatric population aged between 1 month and 17 years who were hospitalized with a diagnosis of CAP in 13 hospitals in Colombia, in whom an IS sample was obtained. Gram staining, aerobic bacterial and mycobacterial culture tests, and polymerase chain reaction (PCR) for 6 atypical bacteria and 15 respiratory viruses were performed. We evaluated the quality of IS samples. Results: IS samples were collected in 516 of 525 children included in this study. The median age was 32 months, 38.6% were younger than 2 years, and 40.9% were between 2 and 5 years. Two patients had transient hypoxemia during the procedure. The quality of the IS obtained was good in 48.4% and intermediate in 24.5%. Identification of a respiratory pathogen was achieved with an IS sample (with Gram staining, culture test, and PCR) in 372 of 516 children with CAP. Conclusion: Our study shows that IS is an adequate sample for the diagnosis of CAP in pediatric population that required hospitalization. The procedure was safe, well tolerated, and with better diagnostic yields compared with the rest of the samples obtained. Mención de responsabilidad : Zulma Vanessa Rueda, Marcela Bermúdez, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Luisa Fernanda Carmona, Catalina Arango, Jose Luis Albarracín, Lucelly López, Yudy Aguilar, María Angélica Maya, Mónica Trujillo, Ángela Rocio Copete, Cristian Vera, Mariana Herrera, Margarita Rosa Giraldo, Gloria Isabel Niño-Cruz, Lázaro A Vélez Referencia : Int J Infect Dis. 2022 Jan 19;116:348-354. DOI (Digital Object Identifier) : 10.1016/j.ijid.2022.01.026 PMID : 35063681 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(22)00025-X Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
Reservar este documento
Ejemplares (1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001845 AC-2022-016 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
AC-2022-016Adobe Acrobat PDF The Respiratory Rate-Oxygenation Index predicts failure of post-extubation high-flow nasal cannula therapy in intensive care unit patients: a retrospective cohort study / Santiago Cardona Marín
Título : The Respiratory Rate-Oxygenation Index predicts failure of post-extubation high-flow nasal cannula therapy in intensive care unit patients: a retrospective cohort study Tipo de documento : documento electrónico Autores : Santiago Cardona Marín, Autor asociado al HPTU Fecha de publicación : 2022 Títulos uniformes : Revista Brasileira de Terapia Intensiva Idioma : Inglés (eng) Palabras clave : Cannula Oxygenation Respiratory rate Airway extubation Pneumonia Critical care Intensive care units Resumen : Objective: To investigate the applicability of the Respiratory Rate-Oxygenation Index to identify the risk of high-flow nasal cannula failure in post-extubation pneumonia patients. Methods: This was a 2-year retrospective observational study conducted in a reference hospital in Bogotá, Colombia. All patients in whom post-extubation high-flow nasal cannula therapy was used as a bridge to extubation were included in the study. The Respiratory Rate-Oxygenation Index was calculated to assess the risk of post-extubation high-flow nasal cannula failure. Results: A total of 162 patients were included in the study. Of these, 23.5% developed high-flow nasal cannula failure. The Respiratory Rate-Oxygenation Index was significantly lower in patients who had high-flow nasal cannula failure [median (IQR): 10.0 (7.7 - 14.4) versus 12.6 (10.1 - 15.6); p = 0.006]. Respiratory Rate-Oxygenation Index > 4.88 showed a crude OR of 0.23 (95%CI 0.17 - 0.30) and an adjusted OR of 0.89 (95%CI 0.81 - 0.98) stratified by severity and comorbidity. After logistic regression analysis, the Respiratory Rate-Oxygenation Index had an adjusted OR of 0.90 (95%CI 0.82 - 0.98; p = 0.026). The area under the Receiver Operating Characteristic curve for extubation failure was 0.64 (95%CI 0.53 - 0.75; p = 0.06). The Respiratory Rate-Oxygenation Index did not show differences between patients who survived and those who died during the intensive care unit stay. Conclusion: The Respiratory Rate-Oxygenation Index is an accessible tool to identify patients at risk of failing high-flow nasal cannula post-extubation treatment. Prospective studies are needed to broaden the utility in this scenario. Mención de responsabilidad : Yuli V. Fuentes, Katherine Carvajal, Santiago Cardona, Gina Sofia Montaño, Elsa D. Ibáñez-Prada, Alirio Bastidas, Eder Caceres, Ricardo Buitrago, Marcela Poveda, Luis Felipe Reyes Referencia : Rev Bras Ter Intensiva. 2022 Sep 19;34(3):360-366. DOI (Digital Object Identifier) : 10.5935/0103-507X.20220477-en PMID : 36134847 Derechos de uso : CC BY En línea : http://rbti.org.br/artigo/detalhes/0103507X-34-3-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis The Respiratory Rate-Oxygenation Index predicts failure of post-extubation high-flow nasal cannula therapy in intensive care unit patients: a retrospective cohort study [documento electrónico] / Santiago Cardona Marín, Autor asociado al HPTU . - 2022.
Obra : Revista Brasileira de Terapia Intensiva
Idioma : Inglés (eng)
Palabras clave : Cannula Oxygenation Respiratory rate Airway extubation Pneumonia Critical care Intensive care units Resumen : Objective: To investigate the applicability of the Respiratory Rate-Oxygenation Index to identify the risk of high-flow nasal cannula failure in post-extubation pneumonia patients. Methods: This was a 2-year retrospective observational study conducted in a reference hospital in Bogotá, Colombia. All patients in whom post-extubation high-flow nasal cannula therapy was used as a bridge to extubation were included in the study. The Respiratory Rate-Oxygenation Index was calculated to assess the risk of post-extubation high-flow nasal cannula failure. Results: A total of 162 patients were included in the study. Of these, 23.5% developed high-flow nasal cannula failure. The Respiratory Rate-Oxygenation Index was significantly lower in patients who had high-flow nasal cannula failure [median (IQR): 10.0 (7.7 - 14.4) versus 12.6 (10.1 - 15.6); p = 0.006]. Respiratory Rate-Oxygenation Index > 4.88 showed a crude OR of 0.23 (95%CI 0.17 - 0.30) and an adjusted OR of 0.89 (95%CI 0.81 - 0.98) stratified by severity and comorbidity. After logistic regression analysis, the Respiratory Rate-Oxygenation Index had an adjusted OR of 0.90 (95%CI 0.82 - 0.98; p = 0.026). The area under the Receiver Operating Characteristic curve for extubation failure was 0.64 (95%CI 0.53 - 0.75; p = 0.06). The Respiratory Rate-Oxygenation Index did not show differences between patients who survived and those who died during the intensive care unit stay. Conclusion: The Respiratory Rate-Oxygenation Index is an accessible tool to identify patients at risk of failing high-flow nasal cannula post-extubation treatment. Prospective studies are needed to broaden the utility in this scenario. Mención de responsabilidad : Yuli V. Fuentes, Katherine Carvajal, Santiago Cardona, Gina Sofia Montaño, Elsa D. Ibáñez-Prada, Alirio Bastidas, Eder Caceres, Ricardo Buitrago, Marcela Poveda, Luis Felipe Reyes Referencia : Rev Bras Ter Intensiva. 2022 Sep 19;34(3):360-366. DOI (Digital Object Identifier) : 10.5935/0103-507X.20220477-en PMID : 36134847 Derechos de uso : CC BY En línea : http://rbti.org.br/artigo/detalhes/0103507X-34-3-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
Reservar este documento
Ejemplares (1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001952 AC-2022-113 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
AC-2022-113Adobe Acrobat PDF Breakthrough Hormographiella aspergillata infection in a patient with acute myeloid leukemia receiving posaconazole prophylaxis: a case report and review / Isabel Cristina Ramírez Sánchez
Título : Breakthrough Hormographiella aspergillata infection in a patient with acute myeloid leukemia receiving posaconazole prophylaxis: a case report and review Tipo de documento : documento electrónico Autores : Isabel Cristina Ramírez Sánchez, Autor asociado al HPTU Fecha de publicación : 2020 Títulos uniformes : Mycopathologia Idioma : Inglés (eng) Palabras clave : Antifungal Breakthrough Hormographiella aspergillata Pneumonia Posaconazole Prophylaxis Resumen : Breakthrough invasive infections occur in immunosuppressed patients while they are receiving antifungal agents for both prophylaxis and therapy. Under such conditions, unusual fungal infections emerge. Hormographiella aspergillata is considered an uncommon human pathogen and causes devastating infections. Here, we present a case report of necrotizing pneumonia caused by H. aspergillata as a breakthrough infection in a neutropenic patient and review all previous cases of H. aspergillata infection reported in the literature. Mención de responsabilidad : Ramírez-Sanchez Isabel Cristina, Agredo Diana, Arango Karen Referencia : Mycopathologia. 2020 Dec;185(6):1069-1076. DOI (Digital Object Identifier) : 10.1007/s11046-020-00488-z PMID : 32880829 En línea : https://link.springer.com/article/10.1007/s11046-020-00488-z Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Breakthrough Hormographiella aspergillata infection in a patient with acute myeloid leukemia receiving posaconazole prophylaxis: a case report and review [documento electrónico] / Isabel Cristina Ramírez Sánchez, Autor asociado al HPTU . - 2020.
Obra : Mycopathologia
Idioma : Inglés (eng)
Palabras clave : Antifungal Breakthrough Hormographiella aspergillata Pneumonia Posaconazole Prophylaxis Resumen : Breakthrough invasive infections occur in immunosuppressed patients while they are receiving antifungal agents for both prophylaxis and therapy. Under such conditions, unusual fungal infections emerge. Hormographiella aspergillata is considered an uncommon human pathogen and causes devastating infections. Here, we present a case report of necrotizing pneumonia caused by H. aspergillata as a breakthrough infection in a neutropenic patient and review all previous cases of H. aspergillata infection reported in the literature. Mención de responsabilidad : Ramírez-Sanchez Isabel Cristina, Agredo Diana, Arango Karen Referencia : Mycopathologia. 2020 Dec;185(6):1069-1076. DOI (Digital Object Identifier) : 10.1007/s11046-020-00488-z PMID : 32880829 En línea : https://link.springer.com/article/10.1007/s11046-020-00488-z Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
Reservar este documento
Ejemplares (1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001396 AC-2020-073 Archivo digital Producción Científica Artículos científicos Disponible “Melioidosis in Antioquia, Colombia: an emerging or endemic disease? A cases series” / Franco Eduardo Montúfar Andrade
Título : “Melioidosis in Antioquia, Colombia: an emerging or endemic disease? A cases series” Tipo de documento : documento electrónico Autores : Franco Eduardo Montúfar Andrade, Autor asociado al HPTU Fecha de publicación : 2015 Títulos uniformes : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Melioidosis sepsis pneumonia burkholderia pseudomallei Resumen : Background: Melioidosis is endemic in Malaysia, the southwest of Thailand, and northern Australia. The incidence in Thailand is 4.4/1 000 000 inhabitants, where it causes 19% of community-acquired pneumonia (CAP) and 20% of bacteremic pneumonia, and the mortality is 50%. Sporadic cases have been described in Central and South America. The objective of this study was to describe the clinical and epidemiological features and ecological characteristics of melioidosis in Antioquia, Colombia. Methods: This is a case series description. Results: Seven cases were identified. Burkholderia pseudomallei was isolated from peripheral blood, pleural fluid, and urine and was identified by the automated system VITEK 2 (bioMe ́ rieux) and API 20NE biochemical kit. Five of the cases had a bacteremic form with shock and pulmonary compromise and two of these patients died. The non-bacteremic melioidosis cases had genitourinary, abdominal, and osteoarticular compromise. All patients had comorbidities and lived in rural hot and humid areas in the west central region of Colombia (Antioquia). Diabetes mellitus, renal insufficiency, and other chronic diseases are important risk factors for the development of severe forms. Conclusions: The cases presented here are similar to those occurring in endemic areas regarding comorbidity, risk factors, clinical presentation, and environmental conditions. It is necessary to establish whether melioidosis is an endemic and under-diagnosed disease or an emerging disease in Colombia. Mención de responsabilidad : F E Montúfar, J E Ochoa, H Ortega, L Franco, M C Montúfar, A Monsalve, C Jaramillo, M Zapata Referencia : Int J Infect Dis. 2015 Aug;37:50-7. DOI (Digital Object Identifier) : 10.1016/j.ijid.2015.05.023 PMID : 26051974 Derechos de uso : CC BY-NC-ND En línea : http://www.ijidonline.com/article/S1201-9712(15)00132-0/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis “Melioidosis in Antioquia, Colombia: an emerging or endemic disease? A cases series” [documento electrónico] / Franco Eduardo Montúfar Andrade, Autor asociado al HPTU . - 2015.
Obra : International Journal of Infectious Diseases
Idioma : Inglés (eng)
Palabras clave : Melioidosis sepsis pneumonia burkholderia pseudomallei Resumen : Background: Melioidosis is endemic in Malaysia, the southwest of Thailand, and northern Australia. The incidence in Thailand is 4.4/1 000 000 inhabitants, where it causes 19% of community-acquired pneumonia (CAP) and 20% of bacteremic pneumonia, and the mortality is 50%. Sporadic cases have been described in Central and South America. The objective of this study was to describe the clinical and epidemiological features and ecological characteristics of melioidosis in Antioquia, Colombia. Methods: This is a case series description. Results: Seven cases were identified. Burkholderia pseudomallei was isolated from peripheral blood, pleural fluid, and urine and was identified by the automated system VITEK 2 (bioMe ́ rieux) and API 20NE biochemical kit. Five of the cases had a bacteremic form with shock and pulmonary compromise and two of these patients died. The non-bacteremic melioidosis cases had genitourinary, abdominal, and osteoarticular compromise. All patients had comorbidities and lived in rural hot and humid areas in the west central region of Colombia (Antioquia). Diabetes mellitus, renal insufficiency, and other chronic diseases are important risk factors for the development of severe forms. Conclusions: The cases presented here are similar to those occurring in endemic areas regarding comorbidity, risk factors, clinical presentation, and environmental conditions. It is necessary to establish whether melioidosis is an endemic and under-diagnosed disease or an emerging disease in Colombia. Mención de responsabilidad : F E Montúfar, J E Ochoa, H Ortega, L Franco, M C Montúfar, A Monsalve, C Jaramillo, M Zapata Referencia : Int J Infect Dis. 2015 Aug;37:50-7. DOI (Digital Object Identifier) : 10.1016/j.ijid.2015.05.023 PMID : 26051974 Derechos de uso : CC BY-NC-ND En línea : http://www.ijidonline.com/article/S1201-9712(15)00132-0/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
Reservar este documento
Ejemplares (1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000476 AC-2015-029 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2015-029.pdfAdobe Acrobat PDF Clinical and epidemiological characteristics of pediatric patients with positive serology for mycoplasma pneumoniae, treated in the third level hospital from 2006 to 2008 / Jorge Hernando Donado Gómez ; David Andrés Espinal Botero
Permalink