Inicio
Resultado de la búsqueda
4 búsqueda de la palabra clave 'pituitary neoplasms'
Clasificado(s) por (Año de edición descendente) Refinar búsqueda Genera el flujo rss de la búsqueda
Enlace permanente de la investigaciónPathology of GH-producing pituitary adenomas and GH cell hyperplasia of the pituitary / Luis Vicente Syro Moreno
Título : Pathology of GH-producing pituitary adenomas and GH cell hyperplasia of the pituitary Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2017 Títulos uniformes : Pituitary Idioma : Inglés (eng) Palabras clave : Acromegaly classification diagnosis immunohistochemistry pathology pituitary neoplasms Resumen : Introduction: Histologic, immunohistochemical and electron microscopic studies have provided conclusive evidence that a marked diversity exists between tumors which secrete growth hormone (GH) in excess. GH cell hyperplasia can also be associated with acromegaly in patients with extrapituitary GH—releasing hormone secreting tumors or in familial pituitary tumor syndromes. Materials and methods: A literature search was performed for information regarding pathology, GH-producing tumors and acromegaly. Results: This review summarizes the current knowledge on the morphology of GH-producing and silent GH adenomas, as well as GH hyperplasia of the pituitary. Conclusion: The importance of morphologic classification and identification of different subgroups of patients with GH-producing adenomas and their impact on clinical management is discussed. Mención de responsabilidad : Luis V Syro, Fabio Rotondo, Carlos A Serna, Leon D Ortiz, Kalman Kovacs Referencia : Pituitary. 2017 Feb;20(1):84-92. DOI (Digital Object Identifier) : 10.1007/s11102-016-0748-8 PMID : 27586499 En línea : https://link.springer.com/article/10.1007%2Fs11102-016-0748-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4088 Pathology of GH-producing pituitary adenomas and GH cell hyperplasia of the pituitary [documento electrónico] / Luis Vicente Syro Moreno, . - 2017.
Obra : Pituitary
Idioma : Inglés (eng)
Palabras clave : Acromegaly classification diagnosis immunohistochemistry pathology pituitary neoplasms Resumen : Introduction: Histologic, immunohistochemical and electron microscopic studies have provided conclusive evidence that a marked diversity exists between tumors which secrete growth hormone (GH) in excess. GH cell hyperplasia can also be associated with acromegaly in patients with extrapituitary GH—releasing hormone secreting tumors or in familial pituitary tumor syndromes. Materials and methods: A literature search was performed for information regarding pathology, GH-producing tumors and acromegaly. Results: This review summarizes the current knowledge on the morphology of GH-producing and silent GH adenomas, as well as GH hyperplasia of the pituitary. Conclusion: The importance of morphologic classification and identification of different subgroups of patients with GH-producing adenomas and their impact on clinical management is discussed. Mención de responsabilidad : Luis V Syro, Fabio Rotondo, Carlos A Serna, Leon D Ortiz, Kalman Kovacs Referencia : Pituitary. 2017 Feb;20(1):84-92. DOI (Digital Object Identifier) : 10.1007/s11102-016-0748-8 PMID : 27586499 En línea : https://link.springer.com/article/10.1007%2Fs11102-016-0748-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4088 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000697 AC-2017-086 Archivo digital Producción Científica Artículos científicos Disponible
Título : Pituitary ganglioneuroma: case report and literature review Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2014 Títulos uniformes : Journal of Cytology and Histology Idioma : Inglés (eng) Palabras clave : Electron microscopy ganglioneuroma. immunohistochemistry neuronal tumors pituitary neoplasms Resumen : We present a case of pituitary ganglioneuroma occurring in a 25 year old woman who presented with headache and hemianopsia. The histologic, immunohistochemical, and ultrastructural features of this tumor support the view that these rare hypothalamic-pituitary tumors are independently functioning neurohormonal units. Immunostaining is strongly positive for neuron-specific enolase (NSE) in all tumor cells and cell processes and for synaptophysin in a few cells and fibers. Few cells closely associated with tumor cells are positive for S100 protein. The cell processes are positive for neurofilament antigen. Ultrastructural analysis documents a spectacular neoplasm of neural derivation. The tumor consists of ganglion cells and areas of neuropil. The most typical tumor cells have relatively lucent spherical nucleus with large nucleolus, and abundant cytoplasm harbors compact sacks of RER membranes studded with ribosomes. Particular emphasis is given to the ultrastructural features which strongly support the functional relationship between the tumor components. It should be kept in mind that unusual and rare ganglionic tumors might show a progressive clinical course and needs surgical intervention as the major part of their treatment whereas ontogenetic and pathogenetic mechanisms taking part still need more work to enlighten pituitary neuronal tumorigenesis. Mención de responsabilidad : Aydin Sav, Luis V Syro, Fabio Rotondo, Bernd W Scheithauer,§, Humberto Uribe, Luis C Penagos, Eva Horvath and Kalman Kovacs Referencia : J Cytol Histol 2013;4(1):1-4. DOI (Digital Object Identifier) : 10.4172/2157-7099.1000203 Derechos de uso : CC BY En línea : https://www.omicsonline.org/pituitary-ganglioneuroma-case-report-and-literature- [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3776 Pituitary ganglioneuroma: case report and literature review [documento electrónico] / Luis Vicente Syro Moreno, . - 2014.
Obra : Journal of Cytology and Histology
Idioma : Inglés (eng)
Palabras clave : Electron microscopy ganglioneuroma. immunohistochemistry neuronal tumors pituitary neoplasms Resumen : We present a case of pituitary ganglioneuroma occurring in a 25 year old woman who presented with headache and hemianopsia. The histologic, immunohistochemical, and ultrastructural features of this tumor support the view that these rare hypothalamic-pituitary tumors are independently functioning neurohormonal units. Immunostaining is strongly positive for neuron-specific enolase (NSE) in all tumor cells and cell processes and for synaptophysin in a few cells and fibers. Few cells closely associated with tumor cells are positive for S100 protein. The cell processes are positive for neurofilament antigen. Ultrastructural analysis documents a spectacular neoplasm of neural derivation. The tumor consists of ganglion cells and areas of neuropil. The most typical tumor cells have relatively lucent spherical nucleus with large nucleolus, and abundant cytoplasm harbors compact sacks of RER membranes studded with ribosomes. Particular emphasis is given to the ultrastructural features which strongly support the functional relationship between the tumor components. It should be kept in mind that unusual and rare ganglionic tumors might show a progressive clinical course and needs surgical intervention as the major part of their treatment whereas ontogenetic and pathogenetic mechanisms taking part still need more work to enlighten pituitary neuronal tumorigenesis. Mención de responsabilidad : Aydin Sav, Luis V Syro, Fabio Rotondo, Bernd W Scheithauer,§, Humberto Uribe, Luis C Penagos, Eva Horvath and Kalman Kovacs Referencia : J Cytol Histol 2013;4(1):1-4. DOI (Digital Object Identifier) : 10.4172/2157-7099.1000203 Derechos de uso : CC BY En línea : https://www.omicsonline.org/pituitary-ganglioneuroma-case-report-and-literature- [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3776 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000351 AC-2014-017 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2014-017.pdfAdobe Acrobat PDF
Título : Pituitary tumors in patients with MEN1 syndrome Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2012 Títulos uniformes : Clinics (Sao Paulo) Idioma : Inglés (eng) Palabras clave : Pituitary neoplasms multiple endocrine neoplasia type 1 review genetics Resumen : We briefly review the characteristics of pituitary tumors associated with multiple endocrine neoplasia type 1. Multiple endocrine neoplasia type 1 is an autosomal-dominant disorder most commonly characterized by tumors of the pituitary, parathyroid, endocrine-gastrointestinal tract, and pancreas. A MEDLINE search for all available publications regarding multiple endocrine neoplasia type 1 and pituitary adenomas was undertaken. The prevalence of pituitary tumors in multiple endocrine neoplasia type 1 may vary from 10% to 60% depending on the studied series, and such tumors may occur as the first clinical manifestation of multiple endocrine neoplasia type 1 in 25% of sporadic and 10% of familial cases. Patients were younger and the time between initial and subsequent multiple endocrine neoplasia type 1 endocrine lesions was significantly longer when pituitary disease was the initial manifestation of multiple endocrine neoplasia type 1. Tumors were larger and more invasive and clinical manifestations related to the size of the pituitary adenoma were significantly more frequent in patients with multiple endocrine neoplasia type 1 than in subjects with non-multiple endocrine neoplasia type 1. Normalization of pituitary hypersecretion was much less frequent in patients with multiple endocrine neoplasia type 1 than in subjects with non-multiple endocrine neoplasia type 1. Pituitary tumors in patients with multiple endocrine neoplasia type 1 syndrome tend to be larger, invasive and more symptomatic, and they tend to occur in younger patients when they are the initial presentation of multiple endocrine neoplasia type 1. Mención de responsabilidad : Luis V Syro, Bernd W Scheithauer, Kalman Kovacs, Rodrigo A Toledo, Francisco J Londoño, Leon D Ortiz, Fabio Rotondo, Eva Horvath, Humberto Uribe Referencia : Clinics (Sao Paulo). 2012;67 Suppl 1:43-8. DOI (Digital Object Identifier) : 10.6061/clinics/2012(Sup01)09 PMID : 22584705 En línea : https://www.revistas.usp.br/clinics/article/view/19720 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3610 Pituitary tumors in patients with MEN1 syndrome [documento electrónico] / Luis Vicente Syro Moreno, . - 2012.
Obra : Clinics (Sao Paulo)
Idioma : Inglés (eng)
Palabras clave : Pituitary neoplasms multiple endocrine neoplasia type 1 review genetics Resumen : We briefly review the characteristics of pituitary tumors associated with multiple endocrine neoplasia type 1. Multiple endocrine neoplasia type 1 is an autosomal-dominant disorder most commonly characterized by tumors of the pituitary, parathyroid, endocrine-gastrointestinal tract, and pancreas. A MEDLINE search for all available publications regarding multiple endocrine neoplasia type 1 and pituitary adenomas was undertaken. The prevalence of pituitary tumors in multiple endocrine neoplasia type 1 may vary from 10% to 60% depending on the studied series, and such tumors may occur as the first clinical manifestation of multiple endocrine neoplasia type 1 in 25% of sporadic and 10% of familial cases. Patients were younger and the time between initial and subsequent multiple endocrine neoplasia type 1 endocrine lesions was significantly longer when pituitary disease was the initial manifestation of multiple endocrine neoplasia type 1. Tumors were larger and more invasive and clinical manifestations related to the size of the pituitary adenoma were significantly more frequent in patients with multiple endocrine neoplasia type 1 than in subjects with non-multiple endocrine neoplasia type 1. Normalization of pituitary hypersecretion was much less frequent in patients with multiple endocrine neoplasia type 1 than in subjects with non-multiple endocrine neoplasia type 1. Pituitary tumors in patients with multiple endocrine neoplasia type 1 syndrome tend to be larger, invasive and more symptomatic, and they tend to occur in younger patients when they are the initial presentation of multiple endocrine neoplasia type 1. Mención de responsabilidad : Luis V Syro, Bernd W Scheithauer, Kalman Kovacs, Rodrigo A Toledo, Francisco J Londoño, Leon D Ortiz, Fabio Rotondo, Eva Horvath, Humberto Uribe Referencia : Clinics (Sao Paulo). 2012;67 Suppl 1:43-8. DOI (Digital Object Identifier) : 10.6061/clinics/2012(Sup01)09 PMID : 22584705 En línea : https://www.revistas.usp.br/clinics/article/view/19720 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3610 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000180 AC-2012-020 Archivo digital Producción Científica Artículos científicos Disponible
Título : Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: morphological findings Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2007 Títulos uniformes : Human Pathology Idioma : Inglés (eng) Palabras clave : Pathology Pituitary Pituitary neoplasms Prolactin Temozolomid Resumen : Administration of temozolomide to a 46-year-old man with an invasive aggressive prolactin (PRL)–secreting pituitary neoplasm resulted in improvement of the clinical condition and significant decrease of blood PRL levels. Histologic, immunohistochemical, and electron microscopic study demonstrated marked morphological differences in the tumor exposed to temozolomide compared with the unexposed tumor. Necrosis, hemorrhagic areas, accumulation of connective tissue, focal inflammatory infiltration, and neuronal transformation were seen. Immunohistochemical prognostic indicators showed a reduction in growth potential. Based on the clinical, laboratory, and morphological findings, we recommend temozolomide therapy in patients with pituitary tumors not responding adequately to other treatment options. Mención de responsabilidad : Kalman Kovacs, Eva Horvath, Luis V Syro, Humberto Uribe, Luis C Penagos, Leon D Ortiz, Camilo E Fadul Referencia : Hum Pathol. 2007 Jan;38(1):185-9. DOI (Digital Object Identifier) : 10.1016/j.humpath.2006.07.014 PMID : 17056093 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0046817706004886 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4424 Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: morphological findings [documento electrónico] / Luis Vicente Syro Moreno, . - 2007.
Obra : Human Pathology
Idioma : Inglés (eng)
Palabras clave : Pathology Pituitary Pituitary neoplasms Prolactin Temozolomid Resumen : Administration of temozolomide to a 46-year-old man with an invasive aggressive prolactin (PRL)–secreting pituitary neoplasm resulted in improvement of the clinical condition and significant decrease of blood PRL levels. Histologic, immunohistochemical, and electron microscopic study demonstrated marked morphological differences in the tumor exposed to temozolomide compared with the unexposed tumor. Necrosis, hemorrhagic areas, accumulation of connective tissue, focal inflammatory infiltration, and neuronal transformation were seen. Immunohistochemical prognostic indicators showed a reduction in growth potential. Based on the clinical, laboratory, and morphological findings, we recommend temozolomide therapy in patients with pituitary tumors not responding adequately to other treatment options. Mención de responsabilidad : Kalman Kovacs, Eva Horvath, Luis V Syro, Humberto Uribe, Luis C Penagos, Leon D Ortiz, Camilo E Fadul Referencia : Hum Pathol. 2007 Jan;38(1):185-9. DOI (Digital Object Identifier) : 10.1016/j.humpath.2006.07.014 PMID : 17056093 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0046817706004886 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4424 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000924 AC-2007-019 Archivo digital Producción Científica Artículos científicos Disponible
