Título : |
High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: A multinational experience in 990 cases from Latin America |
Tipo de documento : |
documento electrónico |
Autores : |
Andrea Parra Buitrago, Autor asociado al HPTU ; Lina María Betancur Londoño, Autor asociado al HPTU |
Fecha de publicación : |
2021 |
Títulos uniformes : |
Acta Paediatrica
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Idioma : |
Inglés (eng) |
Palabras clave : |
COVID-19 SARS-COV-2 antibiotics stewardship |
Resumen : |
Aim: This study aims to assess rates of antibiotic prescriptions and its determinants in in children with COVID-19 or Multisystem Inflammatory Syndrome (MIS-C). Methods: Children <18 years-old assessed in five Latin Americas countries with a diagnosis of COVID-19 or MIS-C were enrolled. Antibiotic prescriptions and factors associated with their use were assessed. Results: A total of 990 children were included: 921 (93%) with COVID-19, 69 (7.0%) with MIS-C. The prevalence of antibiotic use was 24.5% (n = 243). MIS-C with (OR = 45.48) or without (OR = 10.35) cardiac involvement, provision of intensive care (OR = 9.60), need for hospital care (OR = 6.87), pneumonia and/or ARDS detected through chest X-rays (OR = 4.40), administration of systemic corticosteroids (OR = 4.39), oxygen support, mechanical ventilation or CPAP (OR = 2.21), pyrexia (OR = 1.84), and female sex (OR = 1.50) were independently associated with increased use of antibiotics. There was significant variation in antibiotic use across the hospitals. Conclusion: Our study showed a high rate of antibiotic prescriptions in children with COVID-19, in particular in those with severe disease or MIS-C. Prospective studies are needed to provide better evidence on the recognition and management of bacterial infections in COVID-19 children. |
Mención de responsabilidad : |
Acta Paediatr. 2021 Jun;110(6):1902-1910. |
Referencia : |
10.1111/apa.15847 |
DOI (Digital Object Identifier) : |
33742466 |
En línea : |
https://onlinelibrary.wiley.com/doi/10.1111/apa.15847 |
Formato del recurso electrónico : |
Adriana Yock-Corrales, Jacopo Lenzi, Rolando Ulloa-Gutiérrez, Jessica Gómez-Vargas, Omar Yassef Antúnez-Montes, Jorge Alberto Rios Aida, Olguita del Aguila, Erick Arteaga-Menchaca, Francisco Campos, Fadia Uribe, Andrea Parra Buitrago, Lina Maria Betancur |
Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: A multinational experience in 990 cases from Latin America [documento electrónico] / Andrea Parra Buitrago, Autor asociado al HPTU ; Lina María Betancur Londoño, Autor asociado al HPTU . - 2021. Obra : Acta PaediatricaIdioma : Inglés ( eng)
Palabras clave : |
COVID-19 SARS-COV-2 antibiotics stewardship |
Resumen : |
Aim: This study aims to assess rates of antibiotic prescriptions and its determinants in in children with COVID-19 or Multisystem Inflammatory Syndrome (MIS-C). Methods: Children <18 years-old assessed in five Latin Americas countries with a diagnosis of COVID-19 or MIS-C were enrolled. Antibiotic prescriptions and factors associated with their use were assessed. Results: A total of 990 children were included: 921 (93%) with COVID-19, 69 (7.0%) with MIS-C. The prevalence of antibiotic use was 24.5% (n = 243). MIS-C with (OR = 45.48) or without (OR = 10.35) cardiac involvement, provision of intensive care (OR = 9.60), need for hospital care (OR = 6.87), pneumonia and/or ARDS detected through chest X-rays (OR = 4.40), administration of systemic corticosteroids (OR = 4.39), oxygen support, mechanical ventilation or CPAP (OR = 2.21), pyrexia (OR = 1.84), and female sex (OR = 1.50) were independently associated with increased use of antibiotics. There was significant variation in antibiotic use across the hospitals. Conclusion: Our study showed a high rate of antibiotic prescriptions in children with COVID-19, in particular in those with severe disease or MIS-C. Prospective studies are needed to provide better evidence on the recognition and management of bacterial infections in COVID-19 children. |
Mención de responsabilidad : |
Acta Paediatr. 2021 Jun;110(6):1902-1910. |
Referencia : |
10.1111/apa.15847 |
DOI (Digital Object Identifier) : |
33742466 |
En línea : |
https://onlinelibrary.wiley.com/doi/10.1111/apa.15847 |
Formato del recurso electrónico : |
Adriana Yock-Corrales, Jacopo Lenzi, Rolando Ulloa-Gutiérrez, Jessica Gómez-Vargas, Omar Yassef Antúnez-Montes, Jorge Alberto Rios Aida, Olguita del Aguila, Erick Arteaga-Menchaca, Francisco Campos, Fadia Uribe, Andrea Parra Buitrago, Lina Maria Betancur |
Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
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