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Refinar búsquedaCandida tropicalis Invasive Infection in Febrile Neutropenia, a High Mortality Infection / Arango, Marcos ; Ramírez, Isabel C.
Título : Candida tropicalis Invasive Infection in Febrile Neutropenia, a High Mortality Infection Tipo de documento : documento electrónico Autores : Arango, Marcos, Autor ; Ramírez, Isabel C., Autor Fecha de publicación : 2025 Títulos uniformes : Open Forum Infectious Diseases Idioma : Inglés (eng) Resumen : Invasive candidiasis due to species other than Candida albicans emerges as a problem in neutropenic patients receiving antifungal prophylaxis, due to decreased susceptibility to triazoles. Candida tropicalis is the most frequently species in this population and is associated with higher mortality when compared to Candida albicans. The aim of this study is to characterize the neutropenic population with invasive candidiasis and establish differences in outcome of patients with Candida tropicalis infection compared to other Candida species. Characteristics of patients with invasive candidiasis Mención de responsabilidad : Marcos Arango, Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2421 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2421 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2421/7988378?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Candida tropicalis Invasive Infection in Febrile Neutropenia, a High Mortality Infection [documento electrónico] / Arango, Marcos, Autor ; Ramírez, Isabel C., Autor . - 2025.
Obra : Open Forum Infectious Diseases
Idioma : Inglés (eng)
Resumen : Invasive candidiasis due to species other than Candida albicans emerges as a problem in neutropenic patients receiving antifungal prophylaxis, due to decreased susceptibility to triazoles. Candida tropicalis is the most frequently species in this population and is associated with higher mortality when compared to Candida albicans. The aim of this study is to characterize the neutropenic population with invasive candidiasis and establish differences in outcome of patients with Candida tropicalis infection compared to other Candida species. Characteristics of patients with invasive candidiasis Mención de responsabilidad : Marcos Arango, Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2421 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2421 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2421/7988378?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Comparative analysis of surgical approaches in nonsyndromic multiple-suture synostosis: a systematic review and meta-analysis Tipo de documento : documento electrónico Autores : Giraldo García, Gustavo, Autor ; Gutiérrez Pineda, Felipe, Autor ; Franklin, Brodus A, Autor ; Punukollu, Anuraag, Autor ; Chen, Hsien Chung, Autor ; Machado Silva, Anna Lydia, Autor ; Proctor, Mark, Autor ; Quiceno, Esteban, Autor Fecha de publicación : 2025 Títulos uniformes : Journal of Neurosurgery: Pediatrics Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave : craniofacial; craniosynostosis; endoscopic surgery; meta-analysis; nonsyndromic multiple-suture synostosis; open surgery. Resumen : Objective: Nonsyndromic multiple-suture synostosis (MSS) is one of the rarest types of craniosynostosis. While both endoscopic and open surgical approaches have demonstrated efficacy for MSS patients, a comprehensive comparison of perioperative outcomes between the two approaches has yet to be fully explored. The aim of this systematic review and meta-analysis was to assess the available evidence among the two surgical approaches to better inform the management of complex craniosynostosis. Methods: PubMed, Embase, and Scopus were searched for studies published from the first reports through February 2024 that reported surgical outcomes of either endoscopic or open surgery for nonsyndromic MSS. The main outcome was the reoperation rate, with secondary endpoints including transfusion rates, intraoperative complications, and overall complications, with a subgroup analysis conducted for patients with nonsyndromic bicoronal synostosis.Results: Sixteen studies involving 310 patients were analyzed. Patients undergoing open surgery were older than those treated with endoscopy (mean age 10.39 vs 3.21 months). The pooled analysis showed a reoperation rate of 11% (95% CI 4%-23%, I2 = 25%) for endoscopic surgery compared with 22% (95% CI 14%-31%, I2 = 0) for open surgery (p = 0.11). Transfusion rates were 26% (95% CI 13%-45%, I2 = 50%) for endoscopic surgery and 50% (95% CI 22%-78%, I2 = 71%) for open surgery (p = 0.18). Intraoperative complications were similar: 17% (95% CI 7%-34%, I2 = 0%) for endoscopic vs 15% (95% CI 4%-42%, I2 = 76%) for open surgery (p = 0.85). Overall complication rates were 15% (95% CI 7%-31%, I2 = 45%) for endoscopic surgery and 20% (95% CI 9%-38%, I2 = 65%) for open surgery (p = 0.59). In the subgroup analysis of bicoronal synostosis, the reoperation rate was 10% (95% CI 4%-21%, I2 = 0%) for endoscopic surgery versus 16% (95% CI 7%-32%, I2 = 0%) for open surgery (p = 0.39).Conclusions: While both surgical approaches are reasonable options for nonsyndromic MSS, this meta-analysis suggests that endoscopic surgery could be associated with lower morbidity when compared with open surgery. Future studies with longer follow-up periods will be needed to validate these findings and contribute to the understanding of complex craniosynostosis management. Mención de responsabilidad : Felipe Gutierrez Pineda, Brodus A. Franklin MHA, MBA, Anuraag Punukollu MBBS, Hsien-Chung Chen MD, Gustavo Giraldo Garcia MD, Anna Lydia Machado Silva, Mark Proctor MD, and Esteban Quiceno Referencia : J Neurosurg Pediatr . 2025 Mar 7;35(5):449-459. DOI (Digital Object Identifier) : 10.3171/2024.11.PEDS24364 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40053929/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Comparative analysis of surgical approaches in nonsyndromic multiple-suture synostosis: a systematic review and meta-analysis [documento electrónico] / Giraldo García, Gustavo, Autor ; Gutiérrez Pineda, Felipe, Autor ; Franklin, Brodus A, Autor ; Punukollu, Anuraag, Autor ; Chen, Hsien Chung, Autor ; Machado Silva, Anna Lydia, Autor ; Proctor, Mark, Autor ; Quiceno, Esteban, Autor . - 2025.
Obra : Journal of Neurosurgery: Pediatrics
Idioma : Inglés (eng) Idioma original : Inglés (eng)
Palabras clave : craniofacial; craniosynostosis; endoscopic surgery; meta-analysis; nonsyndromic multiple-suture synostosis; open surgery. Resumen : Objective: Nonsyndromic multiple-suture synostosis (MSS) is one of the rarest types of craniosynostosis. While both endoscopic and open surgical approaches have demonstrated efficacy for MSS patients, a comprehensive comparison of perioperative outcomes between the two approaches has yet to be fully explored. The aim of this systematic review and meta-analysis was to assess the available evidence among the two surgical approaches to better inform the management of complex craniosynostosis. Methods: PubMed, Embase, and Scopus were searched for studies published from the first reports through February 2024 that reported surgical outcomes of either endoscopic or open surgery for nonsyndromic MSS. The main outcome was the reoperation rate, with secondary endpoints including transfusion rates, intraoperative complications, and overall complications, with a subgroup analysis conducted for patients with nonsyndromic bicoronal synostosis.Results: Sixteen studies involving 310 patients were analyzed. Patients undergoing open surgery were older than those treated with endoscopy (mean age 10.39 vs 3.21 months). The pooled analysis showed a reoperation rate of 11% (95% CI 4%-23%, I2 = 25%) for endoscopic surgery compared with 22% (95% CI 14%-31%, I2 = 0) for open surgery (p = 0.11). Transfusion rates were 26% (95% CI 13%-45%, I2 = 50%) for endoscopic surgery and 50% (95% CI 22%-78%, I2 = 71%) for open surgery (p = 0.18). Intraoperative complications were similar: 17% (95% CI 7%-34%, I2 = 0%) for endoscopic vs 15% (95% CI 4%-42%, I2 = 76%) for open surgery (p = 0.85). Overall complication rates were 15% (95% CI 7%-31%, I2 = 45%) for endoscopic surgery and 20% (95% CI 9%-38%, I2 = 65%) for open surgery (p = 0.59). In the subgroup analysis of bicoronal synostosis, the reoperation rate was 10% (95% CI 4%-21%, I2 = 0%) for endoscopic surgery versus 16% (95% CI 7%-32%, I2 = 0%) for open surgery (p = 0.39).Conclusions: While both surgical approaches are reasonable options for nonsyndromic MSS, this meta-analysis suggests that endoscopic surgery could be associated with lower morbidity when compared with open surgery. Future studies with longer follow-up periods will be needed to validate these findings and contribute to the understanding of complex craniosynostosis management. Mención de responsabilidad : Felipe Gutierrez Pineda, Brodus A. Franklin MHA, MBA, Anuraag Punukollu MBBS, Hsien-Chung Chen MD, Gustavo Giraldo Garcia MD, Anna Lydia Machado Silva, Mark Proctor MD, and Esteban Quiceno Referencia : J Neurosurg Pediatr . 2025 Mar 7;35(5):449-459. DOI (Digital Object Identifier) : 10.3171/2024.11.PEDS24364 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40053929/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Diferencia estandarizada de las características basales de los ensayos clínicos: Estudio metaepidemiológico. Tipo de documento : documento electrónico Autores : Jorge Hernando Donado Gómez, Autor ; Durango Villada, Laura, Autor ; Giraldo Echeverri, Luz María, Autor ; Buitrago Bach, Ricardo, Autor Fecha de publicación : 2025 Títulos uniformes : Salud Uninorte Idioma : Español (spa) Palabras clave : MEDICAL periodicals; RANDOMIZED controlled trials; CLINICAL trials; SAMPLE size (Statistics); SOCIAL factors Resumen : Objective: Establish the difference between standardized mean for quantitative and qualitative variables, exploring its impact in randomized controlled clinical trials based on their sample size. Methodology: Observational, meta-epidemiological study. Inclusion criteria involved parallel-group clinical trials published between January 2021 and August 2022 in four major medical journals worldwide. The exclusion criteria were the participation in clinical trials with more than two groups or arms. Results: It was observed that 99 % of the studies included demographic variables (age, sex, race, or ethnicity), 98 % clinical variables, 45 % treatment-related variables, and 23 % social variables (educational level, marital status). In the analysis of the standardized difference according to sample size, it was found that this value decreased as the number of participants increased, with a mean of 0,12 for the group with fewer than 500 participants and 0,02 for those groups with more than 2000 participants. Conclusions: Studies with larger sample sizes exhibit a tinier standardized mean difference, showing a tendency to be inversely proportional. This finding suggests the importance of considering the sample size when interpreting the results of clinical trials, highlighting the relevance of the consistency and applicability of the findings in studies with extensive numbers of participants. Mención de responsabilidad : DURANGO VILLADA, LAURA; GIRALDO ECHEVERRI, LUZ MARÍA; BUITRAGO BACH, RICARDO; DONADO GÓMEZ, JORGE HERNANDO DOI (Digital Object Identifier) : 10.14482/sun.41.02.484.070 Derechos de uso : CC BY-NC-ND Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Diferencia estandarizada de las características basales de los ensayos clínicos: Estudio metaepidemiológico. [documento electrónico] / Jorge Hernando Donado Gómez, Autor ; Durango Villada, Laura, Autor ; Giraldo Echeverri, Luz María, Autor ; Buitrago Bach, Ricardo, Autor . - 2025.
Obra : Salud Uninorte
Idioma : Español (spa)
Palabras clave : MEDICAL periodicals; RANDOMIZED controlled trials; CLINICAL trials; SAMPLE size (Statistics); SOCIAL factors Resumen : Objective: Establish the difference between standardized mean for quantitative and qualitative variables, exploring its impact in randomized controlled clinical trials based on their sample size. Methodology: Observational, meta-epidemiological study. Inclusion criteria involved parallel-group clinical trials published between January 2021 and August 2022 in four major medical journals worldwide. The exclusion criteria were the participation in clinical trials with more than two groups or arms. Results: It was observed that 99 % of the studies included demographic variables (age, sex, race, or ethnicity), 98 % clinical variables, 45 % treatment-related variables, and 23 % social variables (educational level, marital status). In the analysis of the standardized difference according to sample size, it was found that this value decreased as the number of participants increased, with a mean of 0,12 for the group with fewer than 500 participants and 0,02 for those groups with more than 2000 participants. Conclusions: Studies with larger sample sizes exhibit a tinier standardized mean difference, showing a tendency to be inversely proportional. This finding suggests the importance of considering the sample size when interpreting the results of clinical trials, highlighting the relevance of the consistency and applicability of the findings in studies with extensive numbers of participants. Mención de responsabilidad : DURANGO VILLADA, LAURA; GIRALDO ECHEVERRI, LUZ MARÍA; BUITRAGO BACH, RICARDO; DONADO GÓMEZ, JORGE HERNANDO DOI (Digital Object Identifier) : 10.14482/sun.41.02.484.070 Derechos de uso : CC BY-NC-ND Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data Tipo de documento : documento electrónico Autores : Parra Izquierdo, Viviana, Autor ; Otero Regino, William, Autor ; Fabián Juliao Baños, Autor ; Frías Ordoñez, Juan Sebastián, Autor ; Ibañez Pinilla, Edgar, Autor ; Gil Parada, Fabio Leonel, Autor ; Marulanda Fernández, Hernando, Autor ; Otero Parra, Lina, Autor ; Otero Ramos, Elder, Autor ; Puentes Manosalva, Fabian Eduardo, Autor ; Guzmán Rojas, Gerardo Andrés, Autor ; Ernest Suarez, Kenneth, Autor ; Villa Ovalles, Keyla, Autor ; Paredes Mendez, Juan Eloy, Autor ; Jara Alba, María Luisa, Autor ; Andrade Zamora, David, Autor ; Ardila Báez, Manuel Alonso, Autor ; Floréz Sarmiento, Cristian, Autor ; Veitia, Guillermo, Autor ; Sánchez, Abel, Autor ; Arango Molano, Lazaro Antonio, Autor ; Fluxa, Fernando, Autor ; Freitas Queiroz, Natália Sousa, Autor ; Serrano, Mariastella, Autor Fecha de publicación : 2025 Títulos uniformes : Crohn's and Colitis 360 Idioma : Inglés (eng) Palabras clave : (MeSH): inflammatory bowel diseases; colitis; colonic neoplasms; colonoscopy; prognosis; ulcerative Resumen : Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology. Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity. Surveillance colonoscopies were performed according to available technology. Risk factors for dysplasia detection were analyzed. Results: One hundred and forty-four patients, 55.5% women, mean age 47.3 (range 17.1 to 90; SD 15.64) years and mean duration of disease 12.71 (range 0.64 to 57.13; SD 8.08) years. Forty-nine lesions were identified, 18 corresponded to dysplasia. The detection rate of dysplasia per lesion and per procedure was 36.7% and 12.5%, respectively. By logistic regression analysis, the duration of disease (OR 1.12;95%CI:1.047 to 1.215, P = .002) and the presence of post-inflammatory polyps (OR 3.4;95%CI:1.11 to 10.36, P = .031) were risk factors for higher detection of dysplasia. Digital chromoendoscopy was associated with greater detection of dysplasia (OR 4.99, 95%CI: 1.092 to 22.864, P = .038). Conclusions: In our region, the duration of disease and the presence of post-inflammatory polyps were the factors with the highest association for dysplasia detection, and digital chromoendoscopy with directed biopsies was the technique of choice. The implementation of a specific surveillance program in colonoscopy in IBD is an effective strategy to achieve high detection rates. © 2025 The Author(s). Mención de responsabilidad : Parra-Izquierdo, Viviana, Otero-Regino, William, Juliao-Baños, Fabian, Frías-Ordoñez, Juan Sebastián, Ibañez-Pinilla, Edgar, Gil-Parada, Fabio Leonel, Marulanda-Fernández, Hernando, Otero-Parra, Lina, Otero-Ramos, Elder, Puentes-Manosalva, Fabian Eduardo, Guzmán Rojas, Gerardo Andres, Ernest-Suárez, Kenneth, Villa-Ovalles, Keyla, Paredes-Mendez, Juan Eloy, Jara-Alba, María Luisa, Andrade-Zamora, David, Ardila-Báez, Manuel Alonso, Flórez-Sarmiento, Cristian, Veitia, Guillermo, Sánchez, Abel, Arango-Molano, Lazaro Antonio, Fluxa, Fernando, Freitas Queiroz, Natália Sousa, Serrano, Mariastella Referencia : Crohns Colitis 360 . 2025 Jan 14;7(1):otae081 DOI (Digital Object Identifier) : 10.1093/crocol/otae081 PMID : 39834355 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39834355/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data [documento electrónico] / Parra Izquierdo, Viviana, Autor ; Otero Regino, William, Autor ; Fabián Juliao Baños, Autor ; Frías Ordoñez, Juan Sebastián, Autor ; Ibañez Pinilla, Edgar, Autor ; Gil Parada, Fabio Leonel, Autor ; Marulanda Fernández, Hernando, Autor ; Otero Parra, Lina, Autor ; Otero Ramos, Elder, Autor ; Puentes Manosalva, Fabian Eduardo, Autor ; Guzmán Rojas, Gerardo Andrés, Autor ; Ernest Suarez, Kenneth, Autor ; Villa Ovalles, Keyla, Autor ; Paredes Mendez, Juan Eloy, Autor ; Jara Alba, María Luisa, Autor ; Andrade Zamora, David, Autor ; Ardila Báez, Manuel Alonso, Autor ; Floréz Sarmiento, Cristian, Autor ; Veitia, Guillermo, Autor ; Sánchez, Abel, Autor ; Arango Molano, Lazaro Antonio, Autor ; Fluxa, Fernando, Autor ; Freitas Queiroz, Natália Sousa, Autor ; Serrano, Mariastella, Autor . - 2025.
Obra : Crohn's and Colitis 360
Idioma : Inglés (eng)
Palabras clave : (MeSH): inflammatory bowel diseases; colitis; colonic neoplasms; colonoscopy; prognosis; ulcerative Resumen : Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology. Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity. Surveillance colonoscopies were performed according to available technology. Risk factors for dysplasia detection were analyzed. Results: One hundred and forty-four patients, 55.5% women, mean age 47.3 (range 17.1 to 90; SD 15.64) years and mean duration of disease 12.71 (range 0.64 to 57.13; SD 8.08) years. Forty-nine lesions were identified, 18 corresponded to dysplasia. The detection rate of dysplasia per lesion and per procedure was 36.7% and 12.5%, respectively. By logistic regression analysis, the duration of disease (OR 1.12;95%CI:1.047 to 1.215, P = .002) and the presence of post-inflammatory polyps (OR 3.4;95%CI:1.11 to 10.36, P = .031) were risk factors for higher detection of dysplasia. Digital chromoendoscopy was associated with greater detection of dysplasia (OR 4.99, 95%CI: 1.092 to 22.864, P = .038). Conclusions: In our region, the duration of disease and the presence of post-inflammatory polyps were the factors with the highest association for dysplasia detection, and digital chromoendoscopy with directed biopsies was the technique of choice. The implementation of a specific surveillance program in colonoscopy in IBD is an effective strategy to achieve high detection rates. © 2025 The Author(s). Mención de responsabilidad : Parra-Izquierdo, Viviana, Otero-Regino, William, Juliao-Baños, Fabian, Frías-Ordoñez, Juan Sebastián, Ibañez-Pinilla, Edgar, Gil-Parada, Fabio Leonel, Marulanda-Fernández, Hernando, Otero-Parra, Lina, Otero-Ramos, Elder, Puentes-Manosalva, Fabian Eduardo, Guzmán Rojas, Gerardo Andres, Ernest-Suárez, Kenneth, Villa-Ovalles, Keyla, Paredes-Mendez, Juan Eloy, Jara-Alba, María Luisa, Andrade-Zamora, David, Ardila-Báez, Manuel Alonso, Flórez-Sarmiento, Cristian, Veitia, Guillermo, Sánchez, Abel, Arango-Molano, Lazaro Antonio, Fluxa, Fernando, Freitas Queiroz, Natália Sousa, Serrano, Mariastella Referencia : Crohns Colitis 360 . 2025 Jan 14;7(1):otae081 DOI (Digital Object Identifier) : 10.1093/crocol/otae081 PMID : 39834355 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39834355/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Clinical Outcomes of Hypertonic Saline vs Mannitol Treatment Among Children With Traumatic Brain Injury Tipo de documento : documento electrónico Autores : Juan Camilo Jaramillo Bustamante, Autor ; Chong, Shu Ling, Autor ; Zhu, Yanan, Autor ; Wang, Quan, Autor ; Caporal, Paula, Autor ; Roa, Juan D, Autor ; Pantoja Chamorro, Freddy Israel, Autor ; Teran Miranda, Thelma Elvira, Autor ; Dang, Hongxing, Autor ; Seng Gan, Chin, Autor ; Abbas, Qalab, Autor ; Ardila, Ivan J, Autor ; Antar, Mohannad Ahmad, Autor ; Domínguez Rojas, Jesús A, Autor ; Miñambres Rodríguez, María, Autor ; Zita Watzlawik, Natalia, Autor ; Gómez Arriola, Natalia Elizabeth, Autor ; Yock Corrales, Adriana, Autor ; Lasso Palomino, Rubén Eduardo, Autor ; Mei Xiu, Ming, Autor ; S M Ong, Jacqueline, Autor ; Kurosawa, Hiroshi, Autor ; Aparicio, Gabriela, Autor ; Chunfeng Liu, Autor ; Rujipat, Samransamruajkit, Autor ; Nattachai, Anantasit, Autor ; Yek Kee Chor, Autor ; Turina, Deborah M, Autor ; Pei Chuen Lee, Autor ; Fonseca Flores, Marisol, Autor ; Pilar Orive, Francisco Javier, Autor ; Pei Wen, Jane Ng, Autor ; González Dambrauskas, Sebastián, Autor ; Lee, Jan Hau, Autor Fecha de publicación : 2025 Títulos uniformes : JAMA Network Open Idioma : Inglés (eng) Resumen : Importance: The use of hypertonic saline (HTS) vs mannitol in the control of elevated intracranial pressure (ICP) secondary to neurotrauma is debated. Objective: To compare mortality and functional outcomes of treatment with 3% HTS vs 20% mannitol among children with moderate to severe traumatic brain injury (TBI) at risk of elevated ICP. Design, setting, and participants: This prospective, multicenter cohort study was conducted between June 1, 2018, and December 31, 2022, at 28 participating pediatric intensive care units in the Pediatric Acute and Critical Care Medicine in Asia Network (PACCMAN) and the Red Colaborativa Pediátrica de Latinoamérica (LARed) in Asia, Latin America, and Europe. The study included children (aged Mención de responsabilidad : Shu-Ling Chong, MD, MPH; Yanan Zhu, PhD; Quan Wang, MD; Paula Caporal, MPH; Juan D. Roa, MD; Freddy Israel Pantoja Chamorro, MD;Thelma Elvira Teran Miranda, MD; Hongxing Dang, MD; Chin Seng Gan, MD; Qalab Abbas, MD; Ivan J. Ardila, MD; Mohannad Ahmad Antar, MD;Jesús A. Domínguez-Rojas, MD; María Miñambres Rodríguez, PhD; Natalia Zita Watzlawik, MD; Natalia Elizabeth Gómez Arriola, MD; Adriana Yock-Corrales, MD;Rubén Eduardo Lasso-Palomino, MD; Ming Mei Xiu, MD; Jacqueline S. M. Ong, MD; Hiroshi Kurosawa, MD; Gabriela Aparicio, MD; Chunfeng Liu, MD;Rujipat Samransamruajkit, MD; Juan C. Jaramillo-Bustamante, MD; Nattachai Anantasit, MD; Yek Kee Chor, MD; Deborah M. Turina, MD; Pei Chuen Lee, MD;Marisol Fonseca Flores, MD; Francisco Javier Pilar Orive, PhD; Jane Ng Pei Wen, BSc; Sebastián González-Dambrauskas, MD; Jan Hau Lee, MCI;for the Pediatric Acute and Critical Care Medicine in Asia Network (PACCMAN) and the Red Colaborativa Pediátrica de Latinoamérica (LARed) Referencia : JAMA Netw Open . 2025 Mar 3;8(3):e250438. DOI (Digital Object Identifier) : 10.1001/jamanetworkopen.2025.0438. PMID : 40067302 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40067302/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Clinical Outcomes of Hypertonic Saline vs Mannitol Treatment Among Children With Traumatic Brain Injury [documento electrónico] / Juan Camilo Jaramillo Bustamante, Autor ; Chong, Shu Ling, Autor ; Zhu, Yanan, Autor ; Wang, Quan, Autor ; Caporal, Paula, Autor ; Roa, Juan D, Autor ; Pantoja Chamorro, Freddy Israel, Autor ; Teran Miranda, Thelma Elvira, Autor ; Dang, Hongxing, Autor ; Seng Gan, Chin, Autor ; Abbas, Qalab, Autor ; Ardila, Ivan J, Autor ; Antar, Mohannad Ahmad, Autor ; Domínguez Rojas, Jesús A, Autor ; Miñambres Rodríguez, María, Autor ; Zita Watzlawik, Natalia, Autor ; Gómez Arriola, Natalia Elizabeth, Autor ; Yock Corrales, Adriana, Autor ; Lasso Palomino, Rubén Eduardo, Autor ; Mei Xiu, Ming, Autor ; S M Ong, Jacqueline, Autor ; Kurosawa, Hiroshi, Autor ; Aparicio, Gabriela, Autor ; Chunfeng Liu, Autor ; Rujipat, Samransamruajkit, Autor ; Nattachai, Anantasit, Autor ; Yek Kee Chor, Autor ; Turina, Deborah M, Autor ; Pei Chuen Lee, Autor ; Fonseca Flores, Marisol, Autor ; Pilar Orive, Francisco Javier, Autor ; Pei Wen, Jane Ng, Autor ; González Dambrauskas, Sebastián, Autor ; Lee, Jan Hau, Autor . - 2025.
Obra : JAMA Network Open
Idioma : Inglés (eng)
Resumen : Importance: The use of hypertonic saline (HTS) vs mannitol in the control of elevated intracranial pressure (ICP) secondary to neurotrauma is debated. Objective: To compare mortality and functional outcomes of treatment with 3% HTS vs 20% mannitol among children with moderate to severe traumatic brain injury (TBI) at risk of elevated ICP. Design, setting, and participants: This prospective, multicenter cohort study was conducted between June 1, 2018, and December 31, 2022, at 28 participating pediatric intensive care units in the Pediatric Acute and Critical Care Medicine in Asia Network (PACCMAN) and the Red Colaborativa Pediátrica de Latinoamérica (LARed) in Asia, Latin America, and Europe. The study included children (aged Mención de responsabilidad : Shu-Ling Chong, MD, MPH; Yanan Zhu, PhD; Quan Wang, MD; Paula Caporal, MPH; Juan D. Roa, MD; Freddy Israel Pantoja Chamorro, MD;Thelma Elvira Teran Miranda, MD; Hongxing Dang, MD; Chin Seng Gan, MD; Qalab Abbas, MD; Ivan J. Ardila, MD; Mohannad Ahmad Antar, MD;Jesús A. Domínguez-Rojas, MD; María Miñambres Rodríguez, PhD; Natalia Zita Watzlawik, MD; Natalia Elizabeth Gómez Arriola, MD; Adriana Yock-Corrales, MD;Rubén Eduardo Lasso-Palomino, MD; Ming Mei Xiu, MD; Jacqueline S. M. Ong, MD; Hiroshi Kurosawa, MD; Gabriela Aparicio, MD; Chunfeng Liu, MD;Rujipat Samransamruajkit, MD; Juan C. Jaramillo-Bustamante, MD; Nattachai Anantasit, MD; Yek Kee Chor, MD; Deborah M. Turina, MD; Pei Chuen Lee, MD;Marisol Fonseca Flores, MD; Francisco Javier Pilar Orive, PhD; Jane Ng Pei Wen, BSc; Sebastián González-Dambrauskas, MD; Jan Hau Lee, MCI;for the Pediatric Acute and Critical Care Medicine in Asia Network (PACCMAN) and the Red Colaborativa Pediátrica de Latinoamérica (LARed) Referencia : JAMA Netw Open . 2025 Mar 3;8(3):e250438. DOI (Digital Object Identifier) : 10.1001/jamanetworkopen.2025.0438. PMID : 40067302 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40067302/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002354 AC-2025-037 Archivo digital Producción Científica Artículos científicos Disponible
Título : Healthcare Systems as Determinants of Outcomes in Multiple Myeloma: Final Results from the Latin American MYLACRE Study Tipo de documento : documento electrónico Autores : Kenny Mauricio Gálvez Cárdenas, Autor ; Hungria, Vania, Autor ; Gaiolla, Rafael, Autor ; Remaggi, Guillermina, Autor ; Schutz, Natalia, Autor ; Bittencourt, Rosane, Autor ; Maiolino, Angelo, Autor ; Quintero Vega, Guillermo E, Autor ; Silvana Cugliari, Maria, Autor ; Tobias Braga, Walter Moises, Autor ; Colaco Villarim, Carolina, Autor ; Crusoe, Edvan, Autor ; Enrico, Alicia Ines, Autor ; Caiero, Gaston, Autor ; Bigonha, Jandey, Autor ; Lemos Moura, Fernanda, Autor ; Figueroa, Jair, Autor ; Sossa Melo, Claudia Lucia, Autor ; Lombana, Milton, Autor ; Pei, Huiling, Autor ; Fernandez, Mariana, Autor ; Saes, Jaqueline, Autor ; Trufelli, Damila Cristina, Autor Fecha de publicación : 2025 Títulos uniformes : Blood Advances Idioma : Inglés (eng) Resumen : Although systemic therapy for multiple myeloma (MM) has evolved considerably over the past 2 decades, state-of-the-art treatment is not uniformly available in Latin America. In some countries, disparities between the public and private sectors in clinical presentation, access to novel agents, and transplantation are striking, with the public sector lagging. We conducted a multicenter, observational study of patients with MM in 5 Latin American countries (Argentina, Brazil, Colombia, Mexico, and Panama). We enrolled patients aged ?18 years diagnosed with MM between January 2016 and June 2021, using data collected between May 2019 and June 2022. We categorized institutions as “public” when primarily funded by federal or local government, and “private” when financed mostly or completely by other sources. We analyzed 1029 patients, 1021 of whom could be classified into public (n = 339) and private (n = 682) institutions. These 2 groups differed in many respects, with patients from the latter having better baseline prognostic features (including eligibility to transplantation) and receiving combinations of immunomodulatory drugs and proteasome inhibitors, as well as anti-CD38 antibodies, more frequently than patients from public institutions. Among 960 patients with complete data for this analysis, the median overall survival was 44.6 months in public institutions and 53.3 months in private institutions (hazard ratio, 0.84; 95% confidence interval, 0.67-1.04; P = .109). Our results indicate diagnostic and therapeutic shortcomings in the management of MM in Latin America, with important gaps in patient profile, treatment patterns and long-term outcomes between public and private institutions. Mención de responsabilidad : Vania Hungria, Rafael Gaiolla, Kenny Galvez, Guillermina Remaggi, Natalia Schutz, Rosane Bittencourt, Angelo Maiolino, Guillermo Quintero, Maria Silvana Cugliari, Walter Moises Tobias Braga, Carolina Colaco Villarim, Edvan Crusoe, Alicia Ines Enrico, Gaston Caiero, Jandey Bigonha, Fernanda Lemos Moura, Jair Figueroa, Claudia Lucia Sossa Melo, Milton Lombana, Huiling Pei, Mariana Fernandez, Jaqueline Saes, Damila Cristina Trufelli. Referencia : Blood Advances Volume 9, Issue 6, 25 March 2025, Pages 1293-1302 DOI (Digital Object Identifier) : 10.1182/bloodadvances.2024013838 Derechos de uso : CC BY-NC-ND En línea : https://www.sciencedirect.com/science/article/pii/S2473952924007146 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Healthcare Systems as Determinants of Outcomes in Multiple Myeloma: Final Results from the Latin American MYLACRE Study [documento electrónico] / Kenny Mauricio Gálvez Cárdenas, Autor ; Hungria, Vania, Autor ; Gaiolla, Rafael, Autor ; Remaggi, Guillermina, Autor ; Schutz, Natalia, Autor ; Bittencourt, Rosane, Autor ; Maiolino, Angelo, Autor ; Quintero Vega, Guillermo E, Autor ; Silvana Cugliari, Maria, Autor ; Tobias Braga, Walter Moises, Autor ; Colaco Villarim, Carolina, Autor ; Crusoe, Edvan, Autor ; Enrico, Alicia Ines, Autor ; Caiero, Gaston, Autor ; Bigonha, Jandey, Autor ; Lemos Moura, Fernanda, Autor ; Figueroa, Jair, Autor ; Sossa Melo, Claudia Lucia, Autor ; Lombana, Milton, Autor ; Pei, Huiling, Autor ; Fernandez, Mariana, Autor ; Saes, Jaqueline, Autor ; Trufelli, Damila Cristina, Autor . - 2025.
Obra : Blood Advances
Idioma : Inglés (eng)
Resumen : Although systemic therapy for multiple myeloma (MM) has evolved considerably over the past 2 decades, state-of-the-art treatment is not uniformly available in Latin America. In some countries, disparities between the public and private sectors in clinical presentation, access to novel agents, and transplantation are striking, with the public sector lagging. We conducted a multicenter, observational study of patients with MM in 5 Latin American countries (Argentina, Brazil, Colombia, Mexico, and Panama). We enrolled patients aged ?18 years diagnosed with MM between January 2016 and June 2021, using data collected between May 2019 and June 2022. We categorized institutions as “public” when primarily funded by federal or local government, and “private” when financed mostly or completely by other sources. We analyzed 1029 patients, 1021 of whom could be classified into public (n = 339) and private (n = 682) institutions. These 2 groups differed in many respects, with patients from the latter having better baseline prognostic features (including eligibility to transplantation) and receiving combinations of immunomodulatory drugs and proteasome inhibitors, as well as anti-CD38 antibodies, more frequently than patients from public institutions. Among 960 patients with complete data for this analysis, the median overall survival was 44.6 months in public institutions and 53.3 months in private institutions (hazard ratio, 0.84; 95% confidence interval, 0.67-1.04; P = .109). Our results indicate diagnostic and therapeutic shortcomings in the management of MM in Latin America, with important gaps in patient profile, treatment patterns and long-term outcomes between public and private institutions. Mención de responsabilidad : Vania Hungria, Rafael Gaiolla, Kenny Galvez, Guillermina Remaggi, Natalia Schutz, Rosane Bittencourt, Angelo Maiolino, Guillermo Quintero, Maria Silvana Cugliari, Walter Moises Tobias Braga, Carolina Colaco Villarim, Edvan Crusoe, Alicia Ines Enrico, Gaston Caiero, Jandey Bigonha, Fernanda Lemos Moura, Jair Figueroa, Claudia Lucia Sossa Melo, Milton Lombana, Huiling Pei, Mariana Fernandez, Jaqueline Saes, Damila Cristina Trufelli. Referencia : Blood Advances Volume 9, Issue 6, 25 March 2025, Pages 1293-1302 DOI (Digital Object Identifier) : 10.1182/bloodadvances.2024013838 Derechos de uso : CC BY-NC-ND En línea : https://www.sciencedirect.com/science/article/pii/S2473952924007146 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002345 AC-2025-028 Archivo digital Producción Científica Artículos científicos Disponible
Título : Neurosarcoidosis or granulomatosis with polyangiitis? A complex case of a brain mass Tipo de documento : documento electrónico Autores : Alejandro Vélez Hoyos, Autor ; Luis Fernando Pinto Peñaranda, Autor ; Jiménez Arcia, Luisa Fernanda, Autor ; Crespo Vizcaíno, Estiven, Autor ; González Montoya, Alexandra, Autor Fecha de publicación : 2025 Títulos uniformes : Modern Rheumatology Case Reports Idioma : Inglés (eng) Palabras clave : Neurosarcoidosis sarcoidosis granulomatosis with polyangiitis chronic granulomatous inflammation pachymeningitis Resumen : Sarcoidosis is an immune-mediated systemic disease characterised by the presence of non-caseating granulomas in various parts of the body in the absence of another defined aetiology. Neurologic involvement [neurosarcoidosis (NS)], which occurs in 5–10% of patients with the disease, encompasses a range of clinical and histopathological manifestations that can lead to significant morbidity and mortality. We present a case of a young man with a history of chronic sinusitis, who developed sudden headache associated with seizures. After thorough clinical and paraclinical evaluation, the diagnosis of NS was made once other neurovascular, infectious, metabolic, tumour-related, and immune-mediated aetiologies were ruled out. NS can present as a large dural mass due to nodular pachymeningitis, which can be clinically indistinguishable from other entities such as neoplasms and granulomatosis with polyangiitis. Isolated central nervous system involvement in this entity is rare and usually it is associated with other systemic manifestations. More aggressive management is required to treat this form of sarcoidosis presentation. NS represents a diagnostic challenge and requires ruling out more common entities such as infectious and non-infectious causes like granulomatosis with polyangiitis. Mención de responsabilidad : Vélez Hoyos, Alejandro, Pinto Peñaranda, Luis Fernando, Jiménez Arcia, Luisa Fernanda, Crespo Vizcaíno, Estiven, González Montoya, Alexandra. Referencia : Modern Rheumatology Case Reports, 2025;, rxaf019, DOI (Digital Object Identifier) : 10.1093/mrcr/rxaf019 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/mrcr/advance-article-abstract/doi/10.1093/mrcr/rxaf019/ [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Neurosarcoidosis or granulomatosis with polyangiitis? A complex case of a brain mass [documento electrónico] / Alejandro Vélez Hoyos, Autor ; Luis Fernando Pinto Peñaranda, Autor ; Jiménez Arcia, Luisa Fernanda, Autor ; Crespo Vizcaíno, Estiven, Autor ; González Montoya, Alexandra, Autor . - 2025.
Obra : Modern Rheumatology Case Reports
Idioma : Inglés (eng)
Palabras clave : Neurosarcoidosis sarcoidosis granulomatosis with polyangiitis chronic granulomatous inflammation pachymeningitis Resumen : Sarcoidosis is an immune-mediated systemic disease characterised by the presence of non-caseating granulomas in various parts of the body in the absence of another defined aetiology. Neurologic involvement [neurosarcoidosis (NS)], which occurs in 5–10% of patients with the disease, encompasses a range of clinical and histopathological manifestations that can lead to significant morbidity and mortality. We present a case of a young man with a history of chronic sinusitis, who developed sudden headache associated with seizures. After thorough clinical and paraclinical evaluation, the diagnosis of NS was made once other neurovascular, infectious, metabolic, tumour-related, and immune-mediated aetiologies were ruled out. NS can present as a large dural mass due to nodular pachymeningitis, which can be clinically indistinguishable from other entities such as neoplasms and granulomatosis with polyangiitis. Isolated central nervous system involvement in this entity is rare and usually it is associated with other systemic manifestations. More aggressive management is required to treat this form of sarcoidosis presentation. NS represents a diagnostic challenge and requires ruling out more common entities such as infectious and non-infectious causes like granulomatosis with polyangiitis. Mención de responsabilidad : Vélez Hoyos, Alejandro, Pinto Peñaranda, Luis Fernando, Jiménez Arcia, Luisa Fernanda, Crespo Vizcaíno, Estiven, González Montoya, Alexandra. Referencia : Modern Rheumatology Case Reports, 2025;, rxaf019, DOI (Digital Object Identifier) : 10.1093/mrcr/rxaf019 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/mrcr/advance-article-abstract/doi/10.1093/mrcr/rxaf019/ [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002377 AC-2025-060 Archivo digital Producción Científica Artículos científicos Disponible
Título : Clostridioides difficile infection in adults Tipo de documento : documento electrónico Autores : Ramirez Muñoz, Fabian, Autor ; Morón Serrano, Santiago, Autor Fecha de publicación : 2025 Títulos uniformes : Acta Colombiana de Cuidado Intensivo Idioma : Español (spa) Palabras clave : Clostridioides difficile; Clostridium infections; Enterocolitis pseudomembranous Resumen : Purpose: This review aims to provide clear and precise information about Clostridioides difficile infection (CDI), with the goal of enabling physicians to understand it and proceed with timely diagnosis and treatment. Data Sources and Study Selection: Databases such as PubMed, Ovid, SciELO, Embase, and MEDLINE were consulted, along with general web searches and references previously known to the authors. Studies, guidelines, and reviews addressing the epidemiology, diagnosis, treatment, and prevention of CDI were included. Data Extraction and Synthesis: Data were extracted from studies analyzing clinical presentation, diagnostic methods, and therapeutic options. The data synthesis aimed to provide a comprehensive view of best practices based on current evidence. Conclusions: CDI is a significant cause of gastrointestinal disease in healthcare settings, particularly following antibiotic use. Its incidence is increasing, even in young people without risk factors. Diagnosis is based on clinical suspicion and the detection of C. difficile toxins or toxigenic genes using molecular biology techniques or enzyme immunoassays. This review emphasizes the importance of rapid detection and the implementation of effective therapies to reduce associated morbidity. © 2024 Asociación Colombiana de Medicina Crítica y Cuidado lntensivo Mención de responsabilidad : Muñoz Ramírez Fabián, Morón Serrano Santiago Referencia : Acta Colombiana de Cuidado IntensivoVolume 25, Issue 1, Pages 91 - 971 January 2025 DOI (Digital Object Identifier) : 10.1016/j.acci.2024.08.008 Derechos de uso : CC BY-NC-ND En línea : https://www-scopus-com.recursosbiblioteca.eia.edu.co/record/display.uri?eid=2-s2 [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Clostridioides difficile infection in adults [documento electrónico] / Ramirez Muñoz, Fabian, Autor ; Morón Serrano, Santiago, Autor . - 2025.
Obra : Acta Colombiana de Cuidado Intensivo
Idioma : Español (spa)
Palabras clave : Clostridioides difficile; Clostridium infections; Enterocolitis pseudomembranous Resumen : Purpose: This review aims to provide clear and precise information about Clostridioides difficile infection (CDI), with the goal of enabling physicians to understand it and proceed with timely diagnosis and treatment. Data Sources and Study Selection: Databases such as PubMed, Ovid, SciELO, Embase, and MEDLINE were consulted, along with general web searches and references previously known to the authors. Studies, guidelines, and reviews addressing the epidemiology, diagnosis, treatment, and prevention of CDI were included. Data Extraction and Synthesis: Data were extracted from studies analyzing clinical presentation, diagnostic methods, and therapeutic options. The data synthesis aimed to provide a comprehensive view of best practices based on current evidence. Conclusions: CDI is a significant cause of gastrointestinal disease in healthcare settings, particularly following antibiotic use. Its incidence is increasing, even in young people without risk factors. Diagnosis is based on clinical suspicion and the detection of C. difficile toxins or toxigenic genes using molecular biology techniques or enzyme immunoassays. This review emphasizes the importance of rapid detection and the implementation of effective therapies to reduce associated morbidity. © 2024 Asociación Colombiana de Medicina Crítica y Cuidado lntensivo Mención de responsabilidad : Muñoz Ramírez Fabián, Morón Serrano Santiago Referencia : Acta Colombiana de Cuidado IntensivoVolume 25, Issue 1, Pages 91 - 971 January 2025 DOI (Digital Object Identifier) : 10.1016/j.acci.2024.08.008 Derechos de uso : CC BY-NC-ND En línea : https://www-scopus-com.recursosbiblioteca.eia.edu.co/record/display.uri?eid=2-s2 [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002336 AC-2025-019 Archivo digital Producción Científica Artículos científicos Disponible
Título : Hacia una nueva comprensión de la ferroptosis Tipo de documento : documento electrónico Autores : Juan Carlos Restrepo Gutiérrez, Autor Fecha de publicación : 2025 Títulos uniformes : Hepatología Idioma : Español (spa) Idioma original : Español (spa) Palabras clave : ferroptosis peróxidos lipídicos metabolismo del hierro. Resumen : La ferroptosis es un tipo de muerte celular regulada, recientemente descrita, caracterizada por la acumulación de peróxidos lipídicos dependientes de hierro, que lleva al daño celular irreversible. A diferencia de la apoptosis u otras formas de necrosis, la ferroptosis es impulsada por el desbalance en el metabolismo del hierro y del glutatión, el principal antioxidante celular. Esta vía ha captado creciente interés en la investigación biomédica debido a su implicación en diversas enfermedades, incluidas aquellas que afectan al hígado.
Mención de responsabilidad : Juan Carlos Restrepo Gutiérrez Referencia : Hepatología, 6(1), 11–12 DOI (Digital Object Identifier) : 10.59093/27112330.130 Derechos de uso : CC BY-NC-ND En línea : https://revistahepatologia.org/index.php/hepa/article/view/130 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Hacia una nueva comprensión de la ferroptosis [documento electrónico] / Juan Carlos Restrepo Gutiérrez, Autor . - 2025.
Obra : Hepatología
Idioma : Español (spa) Idioma original : Español (spa)
Palabras clave : ferroptosis peróxidos lipídicos metabolismo del hierro. Resumen : La ferroptosis es un tipo de muerte celular regulada, recientemente descrita, caracterizada por la acumulación de peróxidos lipídicos dependientes de hierro, que lleva al daño celular irreversible. A diferencia de la apoptosis u otras formas de necrosis, la ferroptosis es impulsada por el desbalance en el metabolismo del hierro y del glutatión, el principal antioxidante celular. Esta vía ha captado creciente interés en la investigación biomédica debido a su implicación en diversas enfermedades, incluidas aquellas que afectan al hígado.
Mención de responsabilidad : Juan Carlos Restrepo Gutiérrez Referencia : Hepatología, 6(1), 11–12 DOI (Digital Object Identifier) : 10.59093/27112330.130 Derechos de uso : CC BY-NC-ND En línea : https://revistahepatologia.org/index.php/hepa/article/view/130 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002368 AC-2025-051 Archivo digital Producción Científica Artículos científicos Disponible
Título : CMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia Tipo de documento : documento electrónico Autores : Laura Fernanda Niño Serna, Autor ; Alejandro Díaz Díaz, Autor ; Mónica Rosa Trujillo Honeysberg, Autor ; Natalia Builes R., Autor ; Arias, Andrés, Autor ; Aristizábal, Beatriz H, Autor Fecha de publicación : 2025 Títulos uniformes : Pediatric Transplantation Idioma : Inglés (eng) Palabras clave : CMV; cytomegalovirus infection; haploidentical; hematopoietic stem cell transplantation; pediatrics; transplantation Resumen : Introduction: Cytomegalovirus (CMV) infection is a frequent complication among hematopoietic stem cell transplant (HSCT) recipients. Data regarding CMV reactivation in children in underdeveloped countries is scarce. This is especially notable considering the increasing utilization of haploidentical-related HSCT with the post-transplant cyclophosphamide platform. This study aimed to describe the incidence, clinical characteristics, and evolution of children with CMV reactivation after HSCT and the possible impact of unmanipulated stem cells with PTCy for GvHD prophylaxis. Methods: Retrospective cohort study of children undergoing hematopoietic stem cell transplantation from January 2012 to June 2022. Baseline characteristics and the clinical course were described. Duration of treatment, initial viral load, and time to clearance of DNAemia by type of transplant were compared using the Kruskal-Wallis test. Survival analysis was performed with the Kaplan–Meier method and log-rank test. All statistical analysis was performed using SPSS software, version 20.0. Results: One hundred sixty-six children were included. Among them, 87% of recipients and 88% of donors were CMV positive. The cumulative incidence of cytomegalovirus DNAemia was 28% at 100 days post-transplantation. There were no differences between different donor types. Overall survival at 1 year was 60%, and non-relapse mortality was observed in 28%. CMV reactivation did not appear to negatively impact 1-year overall survival (OS). Conclusions: Our study found no differences in CMV reactivation rates, treatment duration, viral clearance times, co-infections, or 1-year overall survival across different HSCT donor types. Studies are needed to establish more precise criteria for monitoring recipients, particularly in regions where unmanipulated stem cells with PTCy for GvHD prophylaxis are increasing. © 2025 Wiley Periodicals LLC. Mención de responsabilidad : Arias, Andres, Builes, Natalia, Niño-Serna, Laura, Diaz, Alejandro, Aristizabal, Beatriz H., Trujillo, Monica. Referencia : Pediatr Transplant . 2025 Feb;29(1):e70033 DOI (Digital Object Identifier) : 10.1111/petr.70033 PMID : 39837777 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39837777/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis CMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia [documento electrónico] / Laura Fernanda Niño Serna, Autor ; Alejandro Díaz Díaz, Autor ; Mónica Rosa Trujillo Honeysberg, Autor ; Natalia Builes R., Autor ; Arias, Andrés, Autor ; Aristizábal, Beatriz H, Autor . - 2025.
Obra : Pediatric Transplantation
Idioma : Inglés (eng)
Palabras clave : CMV; cytomegalovirus infection; haploidentical; hematopoietic stem cell transplantation; pediatrics; transplantation Resumen : Introduction: Cytomegalovirus (CMV) infection is a frequent complication among hematopoietic stem cell transplant (HSCT) recipients. Data regarding CMV reactivation in children in underdeveloped countries is scarce. This is especially notable considering the increasing utilization of haploidentical-related HSCT with the post-transplant cyclophosphamide platform. This study aimed to describe the incidence, clinical characteristics, and evolution of children with CMV reactivation after HSCT and the possible impact of unmanipulated stem cells with PTCy for GvHD prophylaxis. Methods: Retrospective cohort study of children undergoing hematopoietic stem cell transplantation from January 2012 to June 2022. Baseline characteristics and the clinical course were described. Duration of treatment, initial viral load, and time to clearance of DNAemia by type of transplant were compared using the Kruskal-Wallis test. Survival analysis was performed with the Kaplan–Meier method and log-rank test. All statistical analysis was performed using SPSS software, version 20.0. Results: One hundred sixty-six children were included. Among them, 87% of recipients and 88% of donors were CMV positive. The cumulative incidence of cytomegalovirus DNAemia was 28% at 100 days post-transplantation. There were no differences between different donor types. Overall survival at 1 year was 60%, and non-relapse mortality was observed in 28%. CMV reactivation did not appear to negatively impact 1-year overall survival (OS). Conclusions: Our study found no differences in CMV reactivation rates, treatment duration, viral clearance times, co-infections, or 1-year overall survival across different HSCT donor types. Studies are needed to establish more precise criteria for monitoring recipients, particularly in regions where unmanipulated stem cells with PTCy for GvHD prophylaxis are increasing. © 2025 Wiley Periodicals LLC. Mención de responsabilidad : Arias, Andres, Builes, Natalia, Niño-Serna, Laura, Diaz, Alejandro, Aristizabal, Beatriz H., Trujillo, Monica. Referencia : Pediatr Transplant . 2025 Feb;29(1):e70033 DOI (Digital Object Identifier) : 10.1111/petr.70033 PMID : 39837777 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39837777/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002325 AC-2025-008 Archivo digital Producción Científica Artículos científicos Disponible
Título : Systematic Review and Meta-Analysis of Prevalence and Population-Level Factors Contributing to Posttraumatic Stress Disorder in Pediatric Intensive Care Survivors Tipo de documento : documento electrónico Autores : Eliana López Barón, Autor ; E Hay, Rebecca, Autor ; O'Hearn, Katie, Autor ; Zorko, David J, Autor ; Lee, Laurie A, Autor ; Mooney, Sarah, Autor ; McQuaid, Cara, Autor ; Henshall, David E, Autor ; Campes Dannenberg, Vanessa, Autor ; Flamenghi, Veronica, Autor ; Thibault Celine, Autor ; Lee, Wai Kit, Autor ; Shi Min Ko, Michelle, Autor ; Cree, Michele, Autor ; Louis, Julia St, Autor ; Heneghan, Julia A, Autor ; Ka Yan Leung, Karen, Autor ; Wood, Andrea, Autor ; Hani Temsah, Mohamad, Autor ; Almazyad, Mohammed, Autor ; Retallack, Jennifer, Autor ; Reddy, Mounika, Autor ; Aldairi, Nedaa, Autor ; Lasso Palomino, Rubén Eduardo, Autor ; Choong, Karen, Autor ; Pont Thibodeau, Geneviève Du, Autor ; Ducharme Crevier, Laurence, Autor ; Tsampalieros, Anne, Autor ; Hayawi, Lamia, Autor ; M McNally, James Dayre, Autor ; Garcia Guerra, Gonzalo, Autor Fecha de publicación : 2025 Títulos uniformes : Pediatric Critical Care Medicine Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave : critical illness; mental health; pediatrics; posttraumatic; stress disorders. Resumen : Objectives: In survivors of illnesses or surgeries requiring PICU admission, there is a risk of posttraumatic stress disorder (PTSD). We aimed to estimate PTSD prevalence and potential contributing factors in survivors of PICU admission. Data sources: We performed a PROSPERO registered systematic review (CRD42022348997; Registered August 2022) using MEDLINE, Embase, CINAHL, and Cochrane Central Register of Controlled Trials (CENTRAL) databases, 2000 to 2022, with no language restrictions. Study selection: Observational or interventional studies evaluating the incidence or prevalence of PTSD in patients' after PICU admission and/or contributing factors to PTSD. We used studies describing patients younger than 18 years old. Since there were a large number of citations, we used an integrated crowdsourcing and machine-learning model for citation screening. Each citation was reviewed independently and in duplicate by two reviewers at each stage of screening and abstraction. Data extraction: Data items included study and participant demographics, details of case definition (PTSD screening), and risk factors. Data synthesis: We followed the Preferred Reporting items for Systematic Reviews and Meta-analysis guidelines. Random-effects models were used to analyze PTSD prevalence and subgroup differences. In 24 citations meeting final review criteria, 19 had data for meta-analysis. There were 1898 PICU survivors with a median (interquartile range) cohort size of 59 (49-76). PTSD prevalence in the studies ranged from 3% to 37%; PTSD occurred in 529 of 1898 survivors ( I2 = 72%). Factors influencing PTSD variability included timing of assessment ( p Mención de responsabilidad : Hay, Rebecca E. MD, MSc(c)1; O’Hearn, Katie MSc2; Zorko, David J. MD, MSc3; Lee, Laurie A. NP, MN, PhD4; Mooney, Sarah BSc(c)5; McQuaid, Cara MD1; Albrecht, Lisa MSc2; Henshall, David E. MD6; Dannenberg, Vanessa Campes PhD7; Flamenghi, Veronica MD8; Thibault, Celine MD9; Lee, Wai Kit MD10; Shi Min Ko, Michelle MD10; Cree, Michele BPharm, GradDipClinPharm11; St. Louis, Julia RN, MN12; Heneghan, Julia A. MD13; Leung, Karen Ka Yan MBBS, MRCPCH14; Wood, Andrea MSc15; López-Barón, Eliana MD16; Temsah, Mohamad-Hani MD17; Almazyad, Mohammed MD17; Retallack, Jennifer MD18; Reddy, Mounika MD, DM19; Aldairi, Nedaa MD20; Palomino, Rubén Eduardo Lasso MD21; Choong, Karen MD, MSc3; Du Pont-Thibodeau, Geneviève MD, MSc9; Ducharme-Crevier, Laurence; Tsampalieros, Anne; Hayawi, Lamia; McNally, James Dayre M; Garcia Guerra, Gonzalo Referencia : Pediatr Crit Care Med . 2025 Apr 1;26(4):e531-e543. DOI (Digital Object Identifier) : 10.1097/PCC.0000000000003696 PMID : 39932370 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39932370/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Systematic Review and Meta-Analysis of Prevalence and Population-Level Factors Contributing to Posttraumatic Stress Disorder in Pediatric Intensive Care Survivors [documento electrónico] / Eliana López Barón, Autor ; E Hay, Rebecca, Autor ; O'Hearn, Katie, Autor ; Zorko, David J, Autor ; Lee, Laurie A, Autor ; Mooney, Sarah, Autor ; McQuaid, Cara, Autor ; Henshall, David E, Autor ; Campes Dannenberg, Vanessa, Autor ; Flamenghi, Veronica, Autor ; Thibault Celine, Autor ; Lee, Wai Kit, Autor ; Shi Min Ko, Michelle, Autor ; Cree, Michele, Autor ; Louis, Julia St, Autor ; Heneghan, Julia A, Autor ; Ka Yan Leung, Karen, Autor ; Wood, Andrea, Autor ; Hani Temsah, Mohamad, Autor ; Almazyad, Mohammed, Autor ; Retallack, Jennifer, Autor ; Reddy, Mounika, Autor ; Aldairi, Nedaa, Autor ; Lasso Palomino, Rubén Eduardo, Autor ; Choong, Karen, Autor ; Pont Thibodeau, Geneviève Du, Autor ; Ducharme Crevier, Laurence, Autor ; Tsampalieros, Anne, Autor ; Hayawi, Lamia, Autor ; M McNally, James Dayre, Autor ; Garcia Guerra, Gonzalo, Autor . - 2025.
Obra : Pediatric Critical Care Medicine
Idioma : Inglés (eng) Idioma original : Inglés (eng)
Palabras clave : critical illness; mental health; pediatrics; posttraumatic; stress disorders. Resumen : Objectives: In survivors of illnesses or surgeries requiring PICU admission, there is a risk of posttraumatic stress disorder (PTSD). We aimed to estimate PTSD prevalence and potential contributing factors in survivors of PICU admission. Data sources: We performed a PROSPERO registered systematic review (CRD42022348997; Registered August 2022) using MEDLINE, Embase, CINAHL, and Cochrane Central Register of Controlled Trials (CENTRAL) databases, 2000 to 2022, with no language restrictions. Study selection: Observational or interventional studies evaluating the incidence or prevalence of PTSD in patients' after PICU admission and/or contributing factors to PTSD. We used studies describing patients younger than 18 years old. Since there were a large number of citations, we used an integrated crowdsourcing and machine-learning model for citation screening. Each citation was reviewed independently and in duplicate by two reviewers at each stage of screening and abstraction. Data extraction: Data items included study and participant demographics, details of case definition (PTSD screening), and risk factors. Data synthesis: We followed the Preferred Reporting items for Systematic Reviews and Meta-analysis guidelines. Random-effects models were used to analyze PTSD prevalence and subgroup differences. In 24 citations meeting final review criteria, 19 had data for meta-analysis. There were 1898 PICU survivors with a median (interquartile range) cohort size of 59 (49-76). PTSD prevalence in the studies ranged from 3% to 37%; PTSD occurred in 529 of 1898 survivors ( I2 = 72%). Factors influencing PTSD variability included timing of assessment ( p Mención de responsabilidad : Hay, Rebecca E. MD, MSc(c)1; O’Hearn, Katie MSc2; Zorko, David J. MD, MSc3; Lee, Laurie A. NP, MN, PhD4; Mooney, Sarah BSc(c)5; McQuaid, Cara MD1; Albrecht, Lisa MSc2; Henshall, David E. MD6; Dannenberg, Vanessa Campes PhD7; Flamenghi, Veronica MD8; Thibault, Celine MD9; Lee, Wai Kit MD10; Shi Min Ko, Michelle MD10; Cree, Michele BPharm, GradDipClinPharm11; St. Louis, Julia RN, MN12; Heneghan, Julia A. MD13; Leung, Karen Ka Yan MBBS, MRCPCH14; Wood, Andrea MSc15; López-Barón, Eliana MD16; Temsah, Mohamad-Hani MD17; Almazyad, Mohammed MD17; Retallack, Jennifer MD18; Reddy, Mounika MD, DM19; Aldairi, Nedaa MD20; Palomino, Rubén Eduardo Lasso MD21; Choong, Karen MD, MSc3; Du Pont-Thibodeau, Geneviève MD, MSc9; Ducharme-Crevier, Laurence; Tsampalieros, Anne; Hayawi, Lamia; McNally, James Dayre M; Garcia Guerra, Gonzalo Referencia : Pediatr Crit Care Med . 2025 Apr 1;26(4):e531-e543. DOI (Digital Object Identifier) : 10.1097/PCC.0000000000003696 PMID : 39932370 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39932370/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Acute myopericarditis associated with Still's disease Otros títulos : Miopericarditis aguda asociada a enfermedad de Still Tipo de documento : documento electrónico Autores : Londoño Barrientos Mateo, Autor ; Londoño Barrientos Mateo, Autor ; Fernández Palacio Alejandro, Autor ; Jairo Alberto Rivera Castro, Autor Fecha de publicación : 2025 Títulos uniformes : Medicina Clínica Idioma : Inglés (eng) Mención de responsabilidad : Mateo Londoño Barrientos, Alejandro Fernández Palacio, Jairo Rivera Castro Referencia : Med Clin (Barc) . 2025 Aug;165(2):107015. doi: 10.1016/j.medcli.2025.107015. Epub 2025 May 30 DOI (Digital Object Identifier) : 10.1016/j.medcli.2025.107015 PMID : 40449025 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40449025/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Acute myopericarditis associated with Still's disease = Miopericarditis aguda asociada a enfermedad de Still [documento electrónico] / Londoño Barrientos Mateo, Autor ; Londoño Barrientos Mateo, Autor ; Fernández Palacio Alejandro, Autor ; Jairo Alberto Rivera Castro, Autor . - 2025.
Obra : Medicina Clínica
Idioma : Inglés (eng)
Mención de responsabilidad : Mateo Londoño Barrientos, Alejandro Fernández Palacio, Jairo Rivera Castro Referencia : Med Clin (Barc) . 2025 Aug;165(2):107015. doi: 10.1016/j.medcli.2025.107015. Epub 2025 May 30 DOI (Digital Object Identifier) : 10.1016/j.medcli.2025.107015 PMID : 40449025 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40449025/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Survival analysis in adult Burkitt Lymphoma in Colombia according to HIV status Tipo de documento : documento electrónico Autores : Laura María Díaz Correa, Autor ; Combariza, Juan Felipe, Autor ; Pineda, Harold, Autor Fecha de publicación : 2025 Títulos uniformes : Cancer Epidemiology Idioma : Inglés (eng) Palabras clave : Burkitt Lymphoma; HIV; Survival Analysis Resumen : Introduction: Burkitt lymphoma is a highly aggressive Non-Hodgkin Lymphoma, is considered a rare tumor, accounts for only 1–2 % of adult lymphomas in North America. The two-year Overall survival rates was reported between 67 % and 84 %. Statistics from developing countries comes mainly from children studies in Africa where Burkitt Lymphoma is endemic. In Latin American countries, information about survival in adult population is scarce with limited number of patients and poor survival outcomes mainly in HIV associated Burkitt Lymphoma. The aim of this study is to evaluate survival in adults’ patients with BL, and HIV status in a Colombian cohort. Materials and methods: A retrospective cohort study was conducted to determine the demographic characteristics, treatment, and survival of adult Burkitt Lymphoma patients in Colombia. The study included adult patients diagnosed with Burkitt Lymphoma between 2004 and 2023, and calculate Overall survival and progression free survival of the population, and according to HIV status Results: 83 patients were included for analysis with 49 (59 %) patients with a sporadic variant and 34 (41 %) with an immunodeficiency-associated variant. The median age at diagnosis was 40 years, IQR (30 – 52), The 36-months OS was 49.9 % (95 % CI; 39.6 – 62.9 %)), and 36-months PFS was 51.5 % (95 % CI¸41.5 – 64.5). For HIV patients 36-months OS was 41 % (95 % CI; 26.7 – 62.7 %) and 59.2 % (95 % CI; 45.8 – 76.6 %) HIV negative HR 1.72 (95 % CI; 0.93 – 1.19 (p = 0.08). Conclusion: this study suggests an OS survival inferior than reported for developed countries with inferior survival rates in HIV patients © 2025 Elsevier Ltd Mención de responsabilidad : Combariza, Juan Felipe; Pineda, Harold; Díaz, Laura. Referencia : Cancer Epidemiol . 2025 Mar 28:96:102805. DOI (Digital Object Identifier) : 10.1016/j.canep.2025.102805 PMID : 40156965 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40156965/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Survival analysis in adult Burkitt Lymphoma in Colombia according to HIV status [documento electrónico] / Laura María Díaz Correa, Autor ; Combariza, Juan Felipe, Autor ; Pineda, Harold, Autor . - 2025.
Obra : Cancer Epidemiology
Idioma : Inglés (eng)
Palabras clave : Burkitt Lymphoma; HIV; Survival Analysis Resumen : Introduction: Burkitt lymphoma is a highly aggressive Non-Hodgkin Lymphoma, is considered a rare tumor, accounts for only 1–2 % of adult lymphomas in North America. The two-year Overall survival rates was reported between 67 % and 84 %. Statistics from developing countries comes mainly from children studies in Africa where Burkitt Lymphoma is endemic. In Latin American countries, information about survival in adult population is scarce with limited number of patients and poor survival outcomes mainly in HIV associated Burkitt Lymphoma. The aim of this study is to evaluate survival in adults’ patients with BL, and HIV status in a Colombian cohort. Materials and methods: A retrospective cohort study was conducted to determine the demographic characteristics, treatment, and survival of adult Burkitt Lymphoma patients in Colombia. The study included adult patients diagnosed with Burkitt Lymphoma between 2004 and 2023, and calculate Overall survival and progression free survival of the population, and according to HIV status Results: 83 patients were included for analysis with 49 (59 %) patients with a sporadic variant and 34 (41 %) with an immunodeficiency-associated variant. The median age at diagnosis was 40 years, IQR (30 – 52), The 36-months OS was 49.9 % (95 % CI; 39.6 – 62.9 %)), and 36-months PFS was 51.5 % (95 % CI¸41.5 – 64.5). For HIV patients 36-months OS was 41 % (95 % CI; 26.7 – 62.7 %) and 59.2 % (95 % CI; 45.8 – 76.6 %) HIV negative HR 1.72 (95 % CI; 0.93 – 1.19 (p = 0.08). Conclusion: this study suggests an OS survival inferior than reported for developed countries with inferior survival rates in HIV patients © 2025 Elsevier Ltd Mención de responsabilidad : Combariza, Juan Felipe; Pineda, Harold; Díaz, Laura. Referencia : Cancer Epidemiol . 2025 Mar 28:96:102805. DOI (Digital Object Identifier) : 10.1016/j.canep.2025.102805 PMID : 40156965 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40156965/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Combining Glucagon-Like Peptide-1 Receptor agonists and Sodium-Glucose Cotransporter-2 Inhibitors in the management of Type 2 Diabetes Mellitus: A protocol for a scoping review Tipo de documento : documento electrónico Autores : Carlos Esteban Builes Montaño, Autor ; Suarez Rodriguez, Andres F., Autor ; Carreño, Johanna, Autor Fecha de publicación : 2025 Títulos uniformes : F1000Research Idioma : Inglés (eng) Palabras clave : Diabetes mellitus; Glucagon-like peptide-1 receptor agonists; Sodium-glucose cotransporter-2 inhibitors. Resumen : Introduction Diabetes treatment has evolved from solely focusing on glucose control to a more patient-centered approach that includes medications designed to reduce specific risks in addition to managing blood glucose control. Methods and analysis We propose a scoping review to explore the available clinical research on the combined use of GLP-1RAs and SGLT2is. This review will adhere to the guidelines outlined in the Joanna Briggs Institute Reviewer’s Manual and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Mención de responsabilidad : Carlos E. Builes-Montaño https://orcid.org/0000-0002-2418-61592,3, Andres F. Suarez-Rodriguez1, Johanna Carreño1 DOI (Digital Object Identifier) : 10.12688/f1000research.159628.1 Derechos de uso : CC BY-NC-ND En línea : https://f1000research.com/articles/14-202 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Combining Glucagon-Like Peptide-1 Receptor agonists and Sodium-Glucose Cotransporter-2 Inhibitors in the management of Type 2 Diabetes Mellitus: A protocol for a scoping review [documento electrónico] / Carlos Esteban Builes Montaño, Autor ; Suarez Rodriguez, Andres F., Autor ; Carreño, Johanna, Autor . - 2025.
Obra : F1000Research
Idioma : Inglés (eng)
Palabras clave : Diabetes mellitus; Glucagon-like peptide-1 receptor agonists; Sodium-glucose cotransporter-2 inhibitors. Resumen : Introduction Diabetes treatment has evolved from solely focusing on glucose control to a more patient-centered approach that includes medications designed to reduce specific risks in addition to managing blood glucose control. Methods and analysis We propose a scoping review to explore the available clinical research on the combined use of GLP-1RAs and SGLT2is. This review will adhere to the guidelines outlined in the Joanna Briggs Institute Reviewer’s Manual and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Mención de responsabilidad : Carlos E. Builes-Montaño https://orcid.org/0000-0002-2418-61592,3, Andres F. Suarez-Rodriguez1, Johanna Carreño1 DOI (Digital Object Identifier) : 10.12688/f1000research.159628.1 Derechos de uso : CC BY-NC-ND En línea : https://f1000research.com/articles/14-202 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002341 AC-2025-024 Archivo digital Producción Científica Artículos científicos Disponible
Título : Cierre de orejuela en pacientes con fibrilación auricular en terapia de reemplazo renal Otros títulos : Atrial appendage closure in patients with atrial fibrillation undergoing renal replacement therapy Tipo de documento : documento electrónico Autores : Niño, Cesar, Autor ; Palmezano Díaz, Jorge M., Autor ; Aristizábal, Julián M., Autor ; Díaz, Juan C., Autor ; Marín, Jorge E., Autor ; Oriana Cristina Bastidas Ayala, Autor ; Mauricio Duque, Autor Fecha de publicación : 2025 Títulos uniformes : Revista Colombiana de Cardiología Idioma : Español (spa) Palabras clave : Fibrilación atrial; Terapia de reemplazo renal; Apéndice atrial; Anticoagulación; Dispositivos de cierre vascular Resumen : Introducción: el cierre de la auriculilla izquierda es una alternativa terapéutica en pacientes con fibrilación auricular no valvular (FANV) con contraindicación para anticoagulación. Los pacientes con terapia de reemplazo renal y FANV tienen alto riesgo embólico, acompañado de un elevadísimo riesgo de sangrado. La anticoagulación no ha demostrado una relación adecuada de riesgo-beneficio. Objetivo: describir la población de pacientes con fibrilación auricular en terapia de reemplazo renal que son llevados a cierre percutáneo de orejuela y dar a conocer los resultados inmediatos de la intervención. Método: estudio descriptivo retrospectivo, multicéntrico, de pacientes con FANV y enfermedad renal crónica en terapia de reemplazo renal llevados a LAAO desde 2017 a 2022. Resultados: serie de 25 pacientes cuya edad promedio fue 68.8 años; 68% fueron hombres, 100% hipertensos, 52% diabéticos y 36% con enfermedad coronaria. El riesgo embólico por CHA2DS2-VASc promedio fue 4 puntos. La función sistólica medida por FEVI fue, en promedio, 55%. El 48% recibía anticoagulante previamente. Respecto al tipo de dispositivo, 76% tenía WATCHMAN y 24% Amulet. El procedimiento fue exitoso en el 96%. Hubo cuatro complicaciones no graves. No se presentaron eventos cerebrovasculares isquémicos ni muertes relacionadas con la intervención. Conclusión: el cierre de la auriculilla izquierda en pacientes con terapia de reemplazo renal ha mostrado ser una alternativa efectiva y segura, con una baja tasa de complicaciones y un seguimiento inicial favorable para los pacientes. Mención de responsabilidad : Jorge M. Palmezano-Díaz, Julián M. Aristizábal, Juan C. Díaz, Jorge E. Marín, César D. Niño, Oriana Bastidas, Juanita Velásquez, Mauricio Duque Referencia : Rev. Colomb. Cardiol. vol.32 no.1 Bogota Jan./Feb. 2025 Epub Mar 05, 2025 DOI (Digital Object Identifier) : 10.24875/rccar.23000067 Derechos de uso : CC BY-NC-ND En línea : http://www.scielo.org.co/scielo.php?pid=S0120-56332025000100019&script=sci_artte [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Cierre de orejuela en pacientes con fibrilación auricular en terapia de reemplazo renal = Atrial appendage closure in patients with atrial fibrillation undergoing renal replacement therapy [documento electrónico] / Niño, Cesar, Autor ; Palmezano Díaz, Jorge M., Autor ; Aristizábal, Julián M., Autor ; Díaz, Juan C., Autor ; Marín, Jorge E., Autor ; Oriana Cristina Bastidas Ayala, Autor ; Mauricio Duque, Autor . - 2025.
Obra : Revista Colombiana de Cardiología
Idioma : Español (spa)
Palabras clave : Fibrilación atrial; Terapia de reemplazo renal; Apéndice atrial; Anticoagulación; Dispositivos de cierre vascular Resumen : Introducción: el cierre de la auriculilla izquierda es una alternativa terapéutica en pacientes con fibrilación auricular no valvular (FANV) con contraindicación para anticoagulación. Los pacientes con terapia de reemplazo renal y FANV tienen alto riesgo embólico, acompañado de un elevadísimo riesgo de sangrado. La anticoagulación no ha demostrado una relación adecuada de riesgo-beneficio. Objetivo: describir la población de pacientes con fibrilación auricular en terapia de reemplazo renal que son llevados a cierre percutáneo de orejuela y dar a conocer los resultados inmediatos de la intervención. Método: estudio descriptivo retrospectivo, multicéntrico, de pacientes con FANV y enfermedad renal crónica en terapia de reemplazo renal llevados a LAAO desde 2017 a 2022. Resultados: serie de 25 pacientes cuya edad promedio fue 68.8 años; 68% fueron hombres, 100% hipertensos, 52% diabéticos y 36% con enfermedad coronaria. El riesgo embólico por CHA2DS2-VASc promedio fue 4 puntos. La función sistólica medida por FEVI fue, en promedio, 55%. El 48% recibía anticoagulante previamente. Respecto al tipo de dispositivo, 76% tenía WATCHMAN y 24% Amulet. El procedimiento fue exitoso en el 96%. Hubo cuatro complicaciones no graves. No se presentaron eventos cerebrovasculares isquémicos ni muertes relacionadas con la intervención. Conclusión: el cierre de la auriculilla izquierda en pacientes con terapia de reemplazo renal ha mostrado ser una alternativa efectiva y segura, con una baja tasa de complicaciones y un seguimiento inicial favorable para los pacientes. Mención de responsabilidad : Jorge M. Palmezano-Díaz, Julián M. Aristizábal, Juan C. Díaz, Jorge E. Marín, César D. Niño, Oriana Bastidas, Juanita Velásquez, Mauricio Duque Referencia : Rev. Colomb. Cardiol. vol.32 no.1 Bogota Jan./Feb. 2025 Epub Mar 05, 2025 DOI (Digital Object Identifier) : 10.24875/rccar.23000067 Derechos de uso : CC BY-NC-ND En línea : http://www.scielo.org.co/scielo.php?pid=S0120-56332025000100019&script=sci_artte [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002373 AC-2025-056 Archivo digital Producción Científica Artículos científicos Disponible
