Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum / Andrés Cárdenas ; Juan Carlos Restrepo Gutiérrez ; Fernando Sierra  

Público ISBD Título : Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum Tipo de documento : documento electrónico Autores : Andrés Cárdenas, ; Juan Carlos Restrepo Gutiérrez, ; Fernando Sierra, Fecha de publicación : 2006 Títulos uniformes : Journal of Clinical Gastroenterology Idioma : Inglés (eng) Palabras clave : Hepatitis  hepatotoxicity  drug-induced liver disease  liver failure  hair supplement  herbal products  shen-min  polygonum multiflorum Resumen : Shen-Min is a herbal product sold as a supplement for women to enhance hair growth. It is widely available across Asia, Europe, and the United States and sold without prescription as a hair nutritional supplement. We describe a case of acute liver injury in a 28-year-old white woman who developed symptomatic hepatitis 8 weeks after starting Shen-Min. All other potential causes of acute hepatitis including viral, hypoxic/ischemic, metabolic, and autoimmune etiologies were excluded. The liver injury slowly resolved over 3 weeks after discontinuing the herbal product. Although the mechanism of Shen-Min hepatotoxicity is unknown, we suspect an idiosyncratic reaction because the patient developed a fine maculopapular rash, mild eosinophilia, and did not overdose. Shen-Min is a Chinese herbal product with a mixture of several plants and vitamins including Polygonum multiflorum, a root that has been previously associated with hepatotoxicity. Nonetheless to our knowledge this is the first reported case of herbal-induced hepatotoxicity in a patient taking Shen-Min per se. Clinicians taking care of patients with acute hepatitis of unclear etiology should be aware that the consumption of Shen-Min, a hair supplement widely available in the United States and Western countries might cause acute hepatitis. Mención de responsabilidad : Cárdenas, Andrés MD, MMS; Restrepo, Juan Carlos MD; Sierra, Fernando MD, MMS; Correa, Gonzalo MD Referencia : J Clin Gastroenterol. 2006 Aug;40(7):629-32. PMID : 16917407 En línea : https://journals.lww.com/jcge/Abstract/2006/08000/Acute_Hepatitis_Due_to_Shen_Mi [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3445 Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum [documento electrónico] / Andrés Cárdenas, ; Juan Carlos Restrepo Gutiérrez, ; Fernando Sierra,  . - 2006. Obra : Journal of Clinical Gastroenterology Idioma : Inglés (eng) Palabras clave : Hepatitis  hepatotoxicity  drug-induced liver disease  liver failure  hair supplement  herbal products  shen-min  polygonum multiflorum Resumen : Shen-Min is a herbal product sold as a supplement for women to enhance hair growth. It is widely available across Asia, Europe, and the United States and sold without prescription as a hair nutritional supplement. We describe a case of acute liver injury in a 28-year-old white woman who developed symptomatic hepatitis 8 weeks after starting Shen-Min. All other potential causes of acute hepatitis including viral, hypoxic/ischemic, metabolic, and autoimmune etiologies were excluded. The liver injury slowly resolved over 3 weeks after discontinuing the herbal product. Although the mechanism of Shen-Min hepatotoxicity is unknown, we suspect an idiosyncratic reaction because the patient developed a fine maculopapular rash, mild eosinophilia, and did not overdose. Shen-Min is a Chinese herbal product with a mixture of several plants and vitamins including Polygonum multiflorum, a root that has been previously associated with hepatotoxicity. Nonetheless to our knowledge this is the first reported case of herbal-induced hepatotoxicity in a patient taking Shen-Min per se. Clinicians taking care of patients with acute hepatitis of unclear etiology should be aware that the consumption of Shen-Min, a hair supplement widely available in the United States and Western countries might cause acute hepatitis. Mención de responsabilidad : Cárdenas, Andrés MD, MMS; Restrepo, Juan Carlos MD; Sierra, Fernando MD, MMS; Correa, Gonzalo MD Referencia : J Clin Gastroenterol. 2006 Aug;40(7):629-32. PMID : 16917407 En línea : https://journals.lww.com/jcge/Abstract/2006/08000/Acute_Hepatitis_Due_to_Shen_Mi [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3445

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