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Refinar búsquedaExperimentar cáncer de mama confronta con la muerte, pero reconcilia con la vida. Estudio cualitativo con el método de la Teoría Fundamentada / Diana Carolina Ríos Cordoba ; Juan David Figueroa Cuesta ; Daniel Fernando Contreras Pérez ; Sandra Isabel Alzate Vanegas ; Carlos Enrique Yepes Delgado
Título : Experimentar cáncer de mama confronta con la muerte, pero reconcilia con la vida. Estudio cualitativo con el método de la Teoría Fundamentada Otros títulos : Experiencing Breast Cancer Confronts Death but Reconciles with Life: A Qualitative Study Using Grounded Theory Methodology Tipo de documento : documento electrónico Autores : Diana Carolina Ríos Cordoba, Autor ; Juan David Figueroa Cuesta, Autor ; Daniel Fernando Contreras Pérez, Autor ; Sandra Isabel Alzate Vanegas, Autor ; Carlos Enrique Yepes Delgado, Autor Fecha de publicación : 2025 Títulos uniformes : Iatreia Idioma : Español (spa) Palabras clave : Acontecimientos que Cambian la Vida; Cuidados para Prolongación de la Vida; Neoplasias de la Mama; Protocolos Antineoplásicos Resumen : Introducción: el cáncer de mama es el diagnóstico oncológico más común en las mujeres y padecerlo genera demandas físicas, psicológicas y sociales. Objetivos: describir el significado que las mujeres construyen alrededor del cáncer de mama y su afrontamiento. Materiales y métodos: estudio hermenéutico con enfoque paradigmático constructivista/interpretativo, basado en la Teoría Fundamentada. Se realizaron 20 entrevistas semiestructuradas a mujeres con diagnóstico de cáncer de mama del Hospital Pablo Tobón Uribe. El análisis utilizó codificación abierta y axial propia de la metodología. Resultados: los principales significados emergidos sobre el cáncer de mama fueron inminencia de muerte y toma de conciencia forzada de la finitud de la vida. La noticia del diagnóstico genera una profunda incertidumbre, miedo ante la posibilidad de morir y los nefastos efectos de tratamiento. Algunas lo afrontan en soledad para proteger del sufrimiento a la familia. El cáncer hace evidente las cargas previas que pesan en la vida: miedos, situaciones, relaciones interpersonales o emociones no resueltas y difíciles de gestionar. El cáncer como experiencia extrema mejora la relación consigo mismo, posibilita reconocer lo esencial en la vida y reevalúa las relaciones con las personas. El trato humanizado y empático del personal de salud ayuda a aliviar el sufrimiento y la angustia. El cáncer cataliza los pensamientos alrededor del sentido de la vida. Conclusiones: la experiencia del cáncer de mama confronta con la muerte, pero reconcilia con la vida, pues la proximidad de la muerte detona el afrontamiento necesario para producir cambios que permiten vivir una vida más gratificante. Mención de responsabilidad : Diana Carolina Ríos-Córdoba, Juan David Figueroa Cuesta, Sandra Isabel Alzate Vanegas, Daniel Fernando Contreras-Pérez, Carlos Enrique Yepes Delgado Referencia : Iatreia; Medellín Tomo 38, N.º 1, (2025). DOI (Digital Object Identifier) : 10.17533/udea.iatreia.289 Derechos de uso : CC BY-NC-SA En línea : https://www.proquest.com/openview/a598348f5657d3fbdc42db2ec6016b79/1?pq-origsite [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Experimentar cáncer de mama confronta con la muerte, pero reconcilia con la vida. Estudio cualitativo con el método de la Teoría Fundamentada = Experiencing Breast Cancer Confronts Death but Reconciles with Life: A Qualitative Study Using Grounded Theory Methodology [documento electrónico] / Diana Carolina Ríos Cordoba, Autor ; Juan David Figueroa Cuesta, Autor ; Daniel Fernando Contreras Pérez, Autor ; Sandra Isabel Alzate Vanegas, Autor ; Carlos Enrique Yepes Delgado, Autor . - 2025.
Obra : Iatreia
Idioma : Español (spa)
Palabras clave : Acontecimientos que Cambian la Vida; Cuidados para Prolongación de la Vida; Neoplasias de la Mama; Protocolos Antineoplásicos Resumen : Introducción: el cáncer de mama es el diagnóstico oncológico más común en las mujeres y padecerlo genera demandas físicas, psicológicas y sociales. Objetivos: describir el significado que las mujeres construyen alrededor del cáncer de mama y su afrontamiento. Materiales y métodos: estudio hermenéutico con enfoque paradigmático constructivista/interpretativo, basado en la Teoría Fundamentada. Se realizaron 20 entrevistas semiestructuradas a mujeres con diagnóstico de cáncer de mama del Hospital Pablo Tobón Uribe. El análisis utilizó codificación abierta y axial propia de la metodología. Resultados: los principales significados emergidos sobre el cáncer de mama fueron inminencia de muerte y toma de conciencia forzada de la finitud de la vida. La noticia del diagnóstico genera una profunda incertidumbre, miedo ante la posibilidad de morir y los nefastos efectos de tratamiento. Algunas lo afrontan en soledad para proteger del sufrimiento a la familia. El cáncer hace evidente las cargas previas que pesan en la vida: miedos, situaciones, relaciones interpersonales o emociones no resueltas y difíciles de gestionar. El cáncer como experiencia extrema mejora la relación consigo mismo, posibilita reconocer lo esencial en la vida y reevalúa las relaciones con las personas. El trato humanizado y empático del personal de salud ayuda a aliviar el sufrimiento y la angustia. El cáncer cataliza los pensamientos alrededor del sentido de la vida. Conclusiones: la experiencia del cáncer de mama confronta con la muerte, pero reconcilia con la vida, pues la proximidad de la muerte detona el afrontamiento necesario para producir cambios que permiten vivir una vida más gratificante. Mención de responsabilidad : Diana Carolina Ríos-Córdoba, Juan David Figueroa Cuesta, Sandra Isabel Alzate Vanegas, Daniel Fernando Contreras-Pérez, Carlos Enrique Yepes Delgado Referencia : Iatreia; Medellín Tomo 38, N.º 1, (2025). DOI (Digital Object Identifier) : 10.17533/udea.iatreia.289 Derechos de uso : CC BY-NC-SA En línea : https://www.proquest.com/openview/a598348f5657d3fbdc42db2ec6016b79/1?pq-origsite [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Prevalence, aetiology, and hospital outcomes of paediatric acute critical illness in resource-constrained settings (Global PARITY): a multicentre, international, point prevalence and prospective cohort study Tipo de documento : documento electrónico Autores : Eliana López Barón, Autor Fecha de publicación : 2025 Títulos uniformes : The Lancet Global Health Idioma : Inglés (eng) Resumen : Background: Children in resource-constrained settings (RCS) have disproportionately high illness and mortality; however, the prevalence in RCS of paediatric acute critical illness (P-ACI; life-threatening conditions that require time-sensitive interventions) is unknown. Most P-ACI can be managed with basic critical care (stabilisation, fluid resuscitation, oxygen, and vital-organ support), but RCS hospitals often lack such essential services. This study estimated the prevalence and examined the aetiology of P-ACI among children at RCS hospitals to support critical care capacity building and inform resource allocation. Methods: We conducted a hybrid prospective cohort and multinational point prevalence study of acutely ill or injured children aged 28 days to 14 years who presented to RCS hospitals on four designated days between July 20, 2021, and July 12, 2022. We measured the proportion of participants with P-ACI, applying the definition for acute paediatric critical illness (DEFCRIT) framework for research in resource-variable settings, and followed up admitted patients for hospital outcomes. In participants with P-ACI, we report diagnoses associated with critical illness. We used descriptive statistics to summarise site and cohort data by country sociodemographic category (Socio-demographic Index; SDI) and multivariable logistic regression to assess whether country sociodemographic category was independently associated with P-ACI. Findings: The study included 46 sites, 19 countries, and 7538 children, among whom 2651 (35·2%) were admitted to hospital and 68 died (all-cause mortality 0·9% [95% CI 0·7–1·1]). 985 (13·1% [95% CI 12·3–13·9]) participants had P-ACI. Among all sociodemographic categories, P-ACI prevalence was highest (28·0% [26·0–30·1]; 512 of 1828 participants) in low-SDI countries (p Mención de responsabilidad : Kortz, Teresa B, Holloway, Adrian, Agulnik, Asya, He, David, Rivera, Stephanie Gordon, Abbas, Qalab, Appiah, John Adabie, Arias, Anita V, Attebery, Jonah, Camacho-Cruz, Jhon, Caporal, Paula, de Sa Rodrigues, Karla Emilia, Fink, Ericka, Kissoon, Niranjan, Lee, Jan Hau, López-Barón, Eliana, Murthy, Srinivas, Muttalib, Fiona, Nielsen, Katie, Remy, Kenneth, Sakaan, Andre-von Arnim, Amelie von Saint, Rodrigues, Adriana Teixeira, Blackwelder, William, Wiens, Matthew, Bhutta, Adnan, Abdul-Mumin, Alhassan, Allen, Nabisere, Amarillo, Paloma,Amegan-Aho, Kokou H, Arancibia, Pamela C, Arif, Fehmina, Arteaga, Liliana Y, Asibey, Jacqueline G, Ávila Guerrero, Nataly, Bacha, Tigist, Beltran Hernandez, Briam D, Bwiza Muhire, Hippolyte, Calderon-Cardenas, Juan S, Cañete, Mariana Lucía, Chimedbazar, Dulamragchaa, Curi, Claudia P, Emmanuel, Tenywa, Escobar, Maria L, Esposto, Sofia, Figueroa Vargas, Arieth, Fustiñana, Ana L, Giulietti, Marina, Habib, Muhammad Irfan, Havugarurema, Pascal, Hernandez Somerson Referencia : Lancet Glob Health . 2025 Feb;13(2):e212-e221. DOI (Digital Object Identifier) : 10.1016/S2214-109X(24)00450-9 PMID : 39890223 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39890223/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Prevalence, aetiology, and hospital outcomes of paediatric acute critical illness in resource-constrained settings (Global PARITY): a multicentre, international, point prevalence and prospective cohort study [documento electrónico] / Eliana López Barón, Autor . - 2025.
Obra : The Lancet Global Health
Idioma : Inglés (eng)
Resumen : Background: Children in resource-constrained settings (RCS) have disproportionately high illness and mortality; however, the prevalence in RCS of paediatric acute critical illness (P-ACI; life-threatening conditions that require time-sensitive interventions) is unknown. Most P-ACI can be managed with basic critical care (stabilisation, fluid resuscitation, oxygen, and vital-organ support), but RCS hospitals often lack such essential services. This study estimated the prevalence and examined the aetiology of P-ACI among children at RCS hospitals to support critical care capacity building and inform resource allocation. Methods: We conducted a hybrid prospective cohort and multinational point prevalence study of acutely ill or injured children aged 28 days to 14 years who presented to RCS hospitals on four designated days between July 20, 2021, and July 12, 2022. We measured the proportion of participants with P-ACI, applying the definition for acute paediatric critical illness (DEFCRIT) framework for research in resource-variable settings, and followed up admitted patients for hospital outcomes. In participants with P-ACI, we report diagnoses associated with critical illness. We used descriptive statistics to summarise site and cohort data by country sociodemographic category (Socio-demographic Index; SDI) and multivariable logistic regression to assess whether country sociodemographic category was independently associated with P-ACI. Findings: The study included 46 sites, 19 countries, and 7538 children, among whom 2651 (35·2%) were admitted to hospital and 68 died (all-cause mortality 0·9% [95% CI 0·7–1·1]). 985 (13·1% [95% CI 12·3–13·9]) participants had P-ACI. Among all sociodemographic categories, P-ACI prevalence was highest (28·0% [26·0–30·1]; 512 of 1828 participants) in low-SDI countries (p Mención de responsabilidad : Kortz, Teresa B, Holloway, Adrian, Agulnik, Asya, He, David, Rivera, Stephanie Gordon, Abbas, Qalab, Appiah, John Adabie, Arias, Anita V, Attebery, Jonah, Camacho-Cruz, Jhon, Caporal, Paula, de Sa Rodrigues, Karla Emilia, Fink, Ericka, Kissoon, Niranjan, Lee, Jan Hau, López-Barón, Eliana, Murthy, Srinivas, Muttalib, Fiona, Nielsen, Katie, Remy, Kenneth, Sakaan, Andre-von Arnim, Amelie von Saint, Rodrigues, Adriana Teixeira, Blackwelder, William, Wiens, Matthew, Bhutta, Adnan, Abdul-Mumin, Alhassan, Allen, Nabisere, Amarillo, Paloma,Amegan-Aho, Kokou H, Arancibia, Pamela C, Arif, Fehmina, Arteaga, Liliana Y, Asibey, Jacqueline G, Ávila Guerrero, Nataly, Bacha, Tigist, Beltran Hernandez, Briam D, Bwiza Muhire, Hippolyte, Calderon-Cardenas, Juan S, Cañete, Mariana Lucía, Chimedbazar, Dulamragchaa, Curi, Claudia P, Emmanuel, Tenywa, Escobar, Maria L, Esposto, Sofia, Figueroa Vargas, Arieth, Fustiñana, Ana L, Giulietti, Marina, Habib, Muhammad Irfan, Havugarurema, Pascal, Hernandez Somerson Referencia : Lancet Glob Health . 2025 Feb;13(2):e212-e221. DOI (Digital Object Identifier) : 10.1016/S2214-109X(24)00450-9 PMID : 39890223 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39890223/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Mixed Fungal Infection in Patients with Hematological Malignancies Tipo de documento : documento electrónico Autores : Ramírez, Isabel C., Autor Fecha de publicación : 2025 Títulos uniformes : Open Forum Infectious Diseases Idioma : Inglés (eng) Resumen : Invasive fungal infection (IFI) is a complication of neutropenia related to hematological malignancy that carries high mortality. Invasive candidiasis remains the predominant cause of yeast infection, followed by molds, primarily Aspergillus, Fusarium, and Mucorales. The clinical spectrum varies, with fungemia and pulmonary IFI being the most common; however, sinusitis, sinopulmonary and disseminated diseases also occur or may have overlapping manifestations. Commensalism and opportunism between microorganisms can favor superinfection as has been previously demonstrated with bacteria and yeasts, virus and mold species, however, mixed fungal infections (MFI) of both yeast and molds are rarely found simultaneously. Mención de responsabilidad : Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2422 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2422 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2422/7988376?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Mixed Fungal Infection in Patients with Hematological Malignancies [documento electrónico] / Ramírez, Isabel C., Autor . - 2025.
Obra : Open Forum Infectious Diseases
Idioma : Inglés (eng)
Resumen : Invasive fungal infection (IFI) is a complication of neutropenia related to hematological malignancy that carries high mortality. Invasive candidiasis remains the predominant cause of yeast infection, followed by molds, primarily Aspergillus, Fusarium, and Mucorales. The clinical spectrum varies, with fungemia and pulmonary IFI being the most common; however, sinusitis, sinopulmonary and disseminated diseases also occur or may have overlapping manifestations. Commensalism and opportunism between microorganisms can favor superinfection as has been previously demonstrated with bacteria and yeasts, virus and mold species, however, mixed fungal infections (MFI) of both yeast and molds are rarely found simultaneously. Mención de responsabilidad : Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2422 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2422 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2422/7988376?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Real World Evidence From 2 Decades of First-Line TKI Therapy in Chronic Myeloid Leukemia (CML): Insights From ACHO's RENEHOC Registry Tipo de documento : documento electrónico Autores : Kenny Mauricio Gálvez Cárdenas, Autor ; Munevar, Isabel, Autor ; Idrobo, Henry, Autor ; Armando Mantilla, William, Autor ; Domingo Saavedra Ramírez, Autor Fecha de publicación : 2025 Títulos uniformes : Clinical Lymphoma, Myeloma and Leukemia Idioma : Inglés (eng) Palabras clave : Dasatinib; Imatinib; Nilotinib; RENEHOC registry; Tyrosine kinase inhibitors Resumen : Background: Chronic myeloid leukemia (CML) treatment has significantly evolved with the introduction of tyrosine kinase inhibitors. However, access to these treatments and outcomes vary globally. This study examines 2 decades of CML management in Colombia using the RENEHOC registry, focusing on TKI efficacy, safety, and healthcare system challenges. Methods: We performed a descriptive analysis of the sociodemographic and clinical characteristics of 994 CML patients from the RENEHOC cohort in Colombia, who were treated over the past 20 years. Trends in first-line TKI use were assessed, and Kaplan-Meier survival curves were used to estimate EFS and OS. The log-rank test was used to compare survival curves between different first-line TKIs. Results: The analysis shows trends in the use of first-line TKIs over a 20-year period in Colombia, where, as in other countries, the use of second-generation TKIs in the first-line setting is gradually increasing. Despite the difficulties of the Colombian healthcare system, the results in terms of OS are excellent regardless of the first-line TKI; however, patients treated with imatinib switched lines significantly more often than those treated with second-generation TKIs (imatinib 58.7%, nilotinib 19.5%, dasatinib 29.3%). The median duration of treatment was significantly shorter with imatinib compared to dasatinib and nilotinib (4.08, 12.75 and not reached, respectively). Intolerance was the most common reason for switching in this cohort of patients. The median observation time for OS was 64.89 months (SD 60.15), with survival rates of 99.4% at 1 year, 97.7% at 3 years and 96.6% at 5 years. Conclusions: The results of this analysis show excellent results in terms of OS for patients with CML treated in Colombia over the last 20 years, despite the difficulties inherent in the health system. Patients treated with first-line imatinib had more frequent line changes. In general, intolerance was the most common reason for switching lines. Despite its retrospective nature, this study allows us to outline how treatment patterns in the country have changed over time. Continued efforts to include more centers and patients in prospective studies are essential to better understand the long-term effects of treatment and to improve adherence to guideline recommendations in clinical practice. © 2024 The Authors Mención de responsabilidad : Abello Polo, Virginia, Sossa, Claudia, Boquimpani, Carla, Salazar, Luis Antonio, Munevar, Isabel, Gómez, Rigoberto, Cuervo, Diana Marcela, Varón Jaimes, Carlos, Reyes, Jheremy, Idrobo, Henry, Omaña, Paola, Daza, Jorge, Pedraza Morales, Julian Eduardo, Agudelo López, Claudia, Quintero-Vega, Guillermo E., Correa Correa, Mario, Herrera, Juan Manuel, Mantilla, William Armando, Serrano, Juan Carlos, Rosales, Carmen, Gálvez Cárdenas, Kenny Mauricio, Bermúdez, Carlos, Saavedra Ramírez, Domingo, Alzate, Mauricio, Lobatón Ramírez, José Fernando Referencia : Clin Lymphoma Myeloma Leuk . 2024 Dec 28:S2152-2650(24)02464-9. DOI (Digital Object Identifier) : 10.1016/j.clml.2024.12.015 PMID : 39863461 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39863461/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Real World Evidence From 2 Decades of First-Line TKI Therapy in Chronic Myeloid Leukemia (CML): Insights From ACHO's RENEHOC Registry [documento electrónico] / Kenny Mauricio Gálvez Cárdenas, Autor ; Munevar, Isabel, Autor ; Idrobo, Henry, Autor ; Armando Mantilla, William, Autor ; Domingo Saavedra Ramírez, Autor . - 2025.
Obra : Clinical Lymphoma, Myeloma and Leukemia
Idioma : Inglés (eng)
Palabras clave : Dasatinib; Imatinib; Nilotinib; RENEHOC registry; Tyrosine kinase inhibitors Resumen : Background: Chronic myeloid leukemia (CML) treatment has significantly evolved with the introduction of tyrosine kinase inhibitors. However, access to these treatments and outcomes vary globally. This study examines 2 decades of CML management in Colombia using the RENEHOC registry, focusing on TKI efficacy, safety, and healthcare system challenges. Methods: We performed a descriptive analysis of the sociodemographic and clinical characteristics of 994 CML patients from the RENEHOC cohort in Colombia, who were treated over the past 20 years. Trends in first-line TKI use were assessed, and Kaplan-Meier survival curves were used to estimate EFS and OS. The log-rank test was used to compare survival curves between different first-line TKIs. Results: The analysis shows trends in the use of first-line TKIs over a 20-year period in Colombia, where, as in other countries, the use of second-generation TKIs in the first-line setting is gradually increasing. Despite the difficulties of the Colombian healthcare system, the results in terms of OS are excellent regardless of the first-line TKI; however, patients treated with imatinib switched lines significantly more often than those treated with second-generation TKIs (imatinib 58.7%, nilotinib 19.5%, dasatinib 29.3%). The median duration of treatment was significantly shorter with imatinib compared to dasatinib and nilotinib (4.08, 12.75 and not reached, respectively). Intolerance was the most common reason for switching in this cohort of patients. The median observation time for OS was 64.89 months (SD 60.15), with survival rates of 99.4% at 1 year, 97.7% at 3 years and 96.6% at 5 years. Conclusions: The results of this analysis show excellent results in terms of OS for patients with CML treated in Colombia over the last 20 years, despite the difficulties inherent in the health system. Patients treated with first-line imatinib had more frequent line changes. In general, intolerance was the most common reason for switching lines. Despite its retrospective nature, this study allows us to outline how treatment patterns in the country have changed over time. Continued efforts to include more centers and patients in prospective studies are essential to better understand the long-term effects of treatment and to improve adherence to guideline recommendations in clinical practice. © 2024 The Authors Mención de responsabilidad : Abello Polo, Virginia, Sossa, Claudia, Boquimpani, Carla, Salazar, Luis Antonio, Munevar, Isabel, Gómez, Rigoberto, Cuervo, Diana Marcela, Varón Jaimes, Carlos, Reyes, Jheremy, Idrobo, Henry, Omaña, Paola, Daza, Jorge, Pedraza Morales, Julian Eduardo, Agudelo López, Claudia, Quintero-Vega, Guillermo E., Correa Correa, Mario, Herrera, Juan Manuel, Mantilla, William Armando, Serrano, Juan Carlos, Rosales, Carmen, Gálvez Cárdenas, Kenny Mauricio, Bermúdez, Carlos, Saavedra Ramírez, Domingo, Alzate, Mauricio, Lobatón Ramírez, José Fernando Referencia : Clin Lymphoma Myeloma Leuk . 2024 Dec 28:S2152-2650(24)02464-9. DOI (Digital Object Identifier) : 10.1016/j.clml.2024.12.015 PMID : 39863461 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39863461/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Handgrip strength as a predictor of 1?year mortality after hip fracture surgery in the Colombian Andes Mountains Tipo de documento : documento electrónico Autores : Toro, Angél, Autor ; González, Fernando Iván, Autor ; Botero, Sandra, Autor ; García, Hernán David, Autor ; Duque, Gustavo, Autor ; Gómez, Fernando, Autor Fecha de publicación : 2025 Títulos uniformes : Osteoporosis International ISBN/ISSN/DL : 98700011909 Idioma : Inglés (eng) Palabras clave : Aging; Colombia Handgrip strength; Hip fracture Mortality Older persons. Clasificación: AC-2025-001 Resumen : Abstract Hip fracture is a public health problem recognized worldwide and a potentially catastrophic threat for older persons, even carrying a demonstrated excess of mortality. Handgrip strength (HGS) has been identified as a predictor of different outcomes (mainly mortality and disability) in several groups with hip fracture. Purpose: The aim of this study was to determine the association between low HGS and 1-year mortality in a cohort of older patients over 60 years old with fragility hip fractures who underwent surgery in the Colombian Andes Mountains. Methods: A total of 126 patients (median age 81 years, women 77%) with a fragility hip fracture during 2019-2020 were admitted to a tertiary care hospital. HGS was measured using dynamometry upon admission, and data about sociodemographic, clinical and functional, laboratory, and surgical intervention variables were collected. They were followed up until discharge. Those who survived were contacted by telephone at one, three, and 12 months. Bivariate, multivariate, and Kaplan-Meier analyses with survival curves were performed. Results: The prevalence of low HGS in the cohort was 71.4%, and these patients were older, had poorer functional and cognitive status, higher comorbidity, higher surgical risk, time from admission to surgery > 72 h, lower hemoglobin and albumin values, and greater intra-hospital mortality at one and three months (all p Mención de responsabilidad : Luis-Ángel Toro 1, Fernando-Iván González 2, Sandra Botero 3, Hernán-David García 1, Gustavo Duque 4 5, Fernando Gómez 6 Referencia : Osteoporos Int . 2025 Jan;36(1):61-69. Epub 2024 Oct 17 DOI (Digital Object Identifier) : 10.1007/s00198-024-07258-3 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39419826/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Handgrip strength as a predictor of 1?year mortality after hip fracture surgery in the Colombian Andes Mountains [documento electrónico] / Toro, Angél, Autor ; González, Fernando Iván, Autor ; Botero, Sandra, Autor ; García, Hernán David, Autor ; Duque, Gustavo, Autor ; Gómez, Fernando, Autor . - 2025.
ISSN : 98700011909
Obra : Osteoporosis International
Idioma : Inglés (eng)
Palabras clave : Aging; Colombia Handgrip strength; Hip fracture Mortality Older persons. Clasificación: AC-2025-001 Resumen : Abstract Hip fracture is a public health problem recognized worldwide and a potentially catastrophic threat for older persons, even carrying a demonstrated excess of mortality. Handgrip strength (HGS) has been identified as a predictor of different outcomes (mainly mortality and disability) in several groups with hip fracture. Purpose: The aim of this study was to determine the association between low HGS and 1-year mortality in a cohort of older patients over 60 years old with fragility hip fractures who underwent surgery in the Colombian Andes Mountains. Methods: A total of 126 patients (median age 81 years, women 77%) with a fragility hip fracture during 2019-2020 were admitted to a tertiary care hospital. HGS was measured using dynamometry upon admission, and data about sociodemographic, clinical and functional, laboratory, and surgical intervention variables were collected. They were followed up until discharge. Those who survived were contacted by telephone at one, three, and 12 months. Bivariate, multivariate, and Kaplan-Meier analyses with survival curves were performed. Results: The prevalence of low HGS in the cohort was 71.4%, and these patients were older, had poorer functional and cognitive status, higher comorbidity, higher surgical risk, time from admission to surgery > 72 h, lower hemoglobin and albumin values, and greater intra-hospital mortality at one and three months (all p Mención de responsabilidad : Luis-Ángel Toro 1, Fernando-Iván González 2, Sandra Botero 3, Hernán-David García 1, Gustavo Duque 4 5, Fernando Gómez 6 Referencia : Osteoporos Int . 2025 Jan;36(1):61-69. Epub 2024 Oct 17 DOI (Digital Object Identifier) : 10.1007/s00198-024-07258-3 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39419826/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Handgrip strength as a predictor of 1?year mortality after hip fracture surgery in the Colombian Andes MountainsURL
Título : Epidemiologic profile of patients with HIV/AIDS in critical care, a Colombian cohort study Tipo de documento : documento electrónico Autores : Sara Catalina Penagos, Autor ; Natalia Zapata Hincapié, Autor ; Juan Pablo Villa Franco, Autor ; Juan José Castro Palacio, Autor ; Serna Patiño, Laura María, Autor ; Peláez, Juan Camilo, Autor ; Agudelo Restrepo, Carlos Andrés, Autor ; Alicia Inés Hidrón Botero, Autor ; Rivera, Sebastián, Autor ; Zapata, Silvana, Autor ; Galeano, Carlos, Autor Fecha de publicación : 2025 Títulos uniformes : Open Forum Infectious Diseases Idioma : Inglés (eng) Resumen : Background The underlying cause of mortality in patients with HIV/AIDS admitted to critical care units has been changing since the advent of highly active antiretroviral therapy (HAART). This study was done to describe the clinical and epidemiologic profile of patients with HIV in a low-middle income country in the HAART era Mención de responsabilidad : Juan José Castro Palacio, Laura Maria Serna Patiño, sara Penagos, Natalia Zapata, Juan pablo villa Franco, Juan Camilo Peláez, Carlos Andres Agudelo Restrepo, Alicia Hidron, sebastian Rivera, Silvana zapata, Carlos Galeano Referencia : Open Forum Infect Dis. 2025 Jan 29;12(Suppl 1):ofae631.631 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.631 PMID : 11776647 Derechos de uso : CC BY-NC-ND En línea : https://pmc.ncbi.nlm.nih.gov/articles/PMC11776647/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Epidemiologic profile of patients with HIV/AIDS in critical care, a Colombian cohort study [documento electrónico] / Sara Catalina Penagos, Autor ; Natalia Zapata Hincapié, Autor ; Juan Pablo Villa Franco, Autor ; Juan José Castro Palacio, Autor ; Serna Patiño, Laura María, Autor ; Peláez, Juan Camilo, Autor ; Agudelo Restrepo, Carlos Andrés, Autor ; Alicia Inés Hidrón Botero, Autor ; Rivera, Sebastián, Autor ; Zapata, Silvana, Autor ; Galeano, Carlos, Autor . - 2025.
Obra : Open Forum Infectious Diseases
Idioma : Inglés (eng)
Resumen : Background The underlying cause of mortality in patients with HIV/AIDS admitted to critical care units has been changing since the advent of highly active antiretroviral therapy (HAART). This study was done to describe the clinical and epidemiologic profile of patients with HIV in a low-middle income country in the HAART era Mención de responsabilidad : Juan José Castro Palacio, Laura Maria Serna Patiño, sara Penagos, Natalia Zapata, Juan pablo villa Franco, Juan Camilo Peláez, Carlos Andres Agudelo Restrepo, Alicia Hidron, sebastian Rivera, Silvana zapata, Carlos Galeano Referencia : Open Forum Infect Dis. 2025 Jan 29;12(Suppl 1):ofae631.631 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.631 PMID : 11776647 Derechos de uso : CC BY-NC-ND En línea : https://pmc.ncbi.nlm.nih.gov/articles/PMC11776647/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Clinical characteristics and post-surgical outcomes in patients with spontaneous pneumothorax: Analysis in a high-complex complexity hospital Otros títulos : Características clínicas y desenlaces postquirúrgicos en pacientes con neumotórax espontáneo: Análisis en un hospital de alta complejidad Tipo de documento : documento electrónico Autores : Willfredy Castaño Ruiz, Autor ; Lina María Velásquez Gómez, Autor ; Sánchez Castro, Carolina, Autor ; Barrantes Moreno, Santiago, Autor ; Bernal Sierra, Sofía, Autor ; Andrés Zerrate Misas, Autor ; Vanegas, Johanna Marcela, Autor Fecha de publicación : 2025 Títulos uniformes : Revista Colombiana de Cirugía Idioma : Inglés (eng) Idioma original : Español (spa) Palabras clave : Pleurodesis; pneumothorax; postoperative complications; thoracic surgical procedures; thoracoscopy; thoracostomy Resumen : Introduction. Spontaneous pneumothorax is a rare pathology that affects both young and old people. It can have a high recurrence rate, resulting in morbidity and sometimes mortality of the patients. In our environment we do not have epidemiological data on the disease, which motivated this study to be carried out. Methods. Retrospective study of a prospective database, which included patients over 14 years of age, with a diagnosis of spontaneous pneumothorax who underwent surgery at the Hospital Pablo Tobón Uribe, Medellin, Colombia, between January 2018 and December 2023. Sociodemographic, clinical variables and postoperative outcomes 30 days after the intervention were analyzed. Results. Males were the most affected (68.2%), secondary spontaneous pneumothorax predominated (56.8%) and the right hemithorax was the most common location (63.6%). A similar incidence was found between smokers and non-smokers (45.4% vs. 52.3%, respectively). Wedge resection was the definitive treatment in 50% of patients and wedge resection associated with mechanical pleurodesis in 31.8%. The most common complication was persistent air leak. A recurrence of pneumothorax was recorded in a patient who had undergone wedge resection. At the end of the study, five patients died: three had been treated only with thoracostomy and two had been taken to surgery. Conclusions. Spontaneous pneumothorax is a rare pathology. The causes and the affected population vary according to the classification. In our environment, tuberculosis has greater relevance because it is an endemic disease. © 2025, Asociacion Colombiana de Cirugia. All rights reserved. Mención de responsabilidad : Sánchez-Castro, Carolina, Barrantes-Moreno, Santiago, Bernal-Sierra, Sofía, Zerrate-Misas, Andrés, Castaño-Ruiz, Willfredy, Vanegas, Johanna Marcela, Velásquez-Gómez, Lina. Referencia : Rev Colomb Cir 2025, 40, 79-88. DOI (Digital Object Identifier) : 10.30944/20117582.2757 Derechos de uso : CC BY-NC-ND En línea : https://www.revistacirugia.org/index.php/cirugia/article/view/2757 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Clinical characteristics and post-surgical outcomes in patients with spontaneous pneumothorax: Analysis in a high-complex complexity hospital = Características clínicas y desenlaces postquirúrgicos en pacientes con neumotórax espontáneo: Análisis en un hospital de alta complejidad [documento electrónico] / Willfredy Castaño Ruiz, Autor ; Lina María Velásquez Gómez, Autor ; Sánchez Castro, Carolina, Autor ; Barrantes Moreno, Santiago, Autor ; Bernal Sierra, Sofía, Autor ; Andrés Zerrate Misas, Autor ; Vanegas, Johanna Marcela, Autor . - 2025.
Obra : Revista Colombiana de Cirugía
Idioma : Inglés (eng) Idioma original : Español (spa)
Palabras clave : Pleurodesis; pneumothorax; postoperative complications; thoracic surgical procedures; thoracoscopy; thoracostomy Resumen : Introduction. Spontaneous pneumothorax is a rare pathology that affects both young and old people. It can have a high recurrence rate, resulting in morbidity and sometimes mortality of the patients. In our environment we do not have epidemiological data on the disease, which motivated this study to be carried out. Methods. Retrospective study of a prospective database, which included patients over 14 years of age, with a diagnosis of spontaneous pneumothorax who underwent surgery at the Hospital Pablo Tobón Uribe, Medellin, Colombia, between January 2018 and December 2023. Sociodemographic, clinical variables and postoperative outcomes 30 days after the intervention were analyzed. Results. Males were the most affected (68.2%), secondary spontaneous pneumothorax predominated (56.8%) and the right hemithorax was the most common location (63.6%). A similar incidence was found between smokers and non-smokers (45.4% vs. 52.3%, respectively). Wedge resection was the definitive treatment in 50% of patients and wedge resection associated with mechanical pleurodesis in 31.8%. The most common complication was persistent air leak. A recurrence of pneumothorax was recorded in a patient who had undergone wedge resection. At the end of the study, five patients died: three had been treated only with thoracostomy and two had been taken to surgery. Conclusions. Spontaneous pneumothorax is a rare pathology. The causes and the affected population vary according to the classification. In our environment, tuberculosis has greater relevance because it is an endemic disease. © 2025, Asociacion Colombiana de Cirugia. All rights reserved. Mención de responsabilidad : Sánchez-Castro, Carolina, Barrantes-Moreno, Santiago, Bernal-Sierra, Sofía, Zerrate-Misas, Andrés, Castaño-Ruiz, Willfredy, Vanegas, Johanna Marcela, Velásquez-Gómez, Lina. Referencia : Rev Colomb Cir 2025, 40, 79-88. DOI (Digital Object Identifier) : 10.30944/20117582.2757 Derechos de uso : CC BY-NC-ND En línea : https://www.revistacirugia.org/index.php/cirugia/article/view/2757 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Introduction to the minisymposium: pediatric infectious diseases in Latin America Tipo de documento : documento electrónico Autores : Cadavid, Lina, Autor ; Ugas Charcape, Carlos F, Autor ; Fazecas, Tatiana, Autor Fecha de publicación : 2025 Títulos uniformes : Pediatric Radiology Idioma : Inglés (eng) Resumen : We are pleased to present the Minisymposium on Pediatric Infectious Diseases in Latin America, featuring six pictorial reviews of key imaging fndings in neglected tropical diseases and tuberculosis. This work highlights pressing regional health challenges, including congenital ZIKV infection, hydatid disease, ascariasis, leishmaniasis, chikungunya, dengue, and CNS and osteoarticular tuberculosis. Neglected tropical diseases disproportionately afect the world’s poorest populations, with over 700,000 deaths annually. Despite recent declines, Latin America reports high incidences, particularly in tropical areas. The COVID-19 pandemic disrupted progress, reducing community interventions and access to care. Meanwhile, tuberculosis, a persistent public health issue, has recently resurged in some countries in the region. Zika virus outbreaks have highlighted its congenital CNS efects, including microcephaly, calcifcations, cerebral atrophy, and corpus callosum anomalies. Ascariasis, prevalent in areas with poor hygiene, often causes gastrointestinal or pulmonary symptoms, with imaging fndings such as real-time movement of echogenic defects on ultrasound and ground-glass or alveolar infltrates on CT. Leishmaniasis often presents with nonspecifc fndings, Dengue can cause hepatosplenomegaly, pleural efusions, gallbladder wall edema, and ascites, with severe cases leading to hemorrhagic manifestations or CNS involvement. Chikungunya typically presents with arthralgia, arthritis, and synovitis. Hydatid disease, afecting multiple organs, relies on imaging for diagnosis, with ultrasound, CT, and MRI crucial for identifying cysts and complications. Tuberculosis in children manifests in the CNS as tuberculomas or meningitis. Osteoarticular tuberculosis accounts for 10–20% of extrapulmonary cases, with common presentations including spondylitis, arthritis, and osteomyelitis. We deeply appreciate Dr. Epelman for inspiring this project, the frst to feature exclusively Latin American authors. Her invaluable guidance made this initiative possible. Through this minisymposium, the Sociedad Latinoamericana de Radiología Pediátrica (SLARP) fulflls its mission to promote regional research and share insights on globally relevant yet underexplored topics, engaging readers worldwidesuch as hepatosplenomegaly and lymphadenopathy. Mención de responsabilidad : Carlos F Ugas Charcape, Lina Cadavid, Tatiana Fazecas. Referencia : Pediatr Radiol . 2025 Jan;55(1):64. DOI (Digital Object Identifier) : 10.1007/s00247-024-06125-x PMID : 39644354 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39644354/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Introduction to the minisymposium: pediatric infectious diseases in Latin America [documento electrónico] / Cadavid, Lina, Autor ; Ugas Charcape, Carlos F, Autor ; Fazecas, Tatiana, Autor . - 2025.
Obra : Pediatric Radiology
Idioma : Inglés (eng)
Resumen : We are pleased to present the Minisymposium on Pediatric Infectious Diseases in Latin America, featuring six pictorial reviews of key imaging fndings in neglected tropical diseases and tuberculosis. This work highlights pressing regional health challenges, including congenital ZIKV infection, hydatid disease, ascariasis, leishmaniasis, chikungunya, dengue, and CNS and osteoarticular tuberculosis. Neglected tropical diseases disproportionately afect the world’s poorest populations, with over 700,000 deaths annually. Despite recent declines, Latin America reports high incidences, particularly in tropical areas. The COVID-19 pandemic disrupted progress, reducing community interventions and access to care. Meanwhile, tuberculosis, a persistent public health issue, has recently resurged in some countries in the region. Zika virus outbreaks have highlighted its congenital CNS efects, including microcephaly, calcifcations, cerebral atrophy, and corpus callosum anomalies. Ascariasis, prevalent in areas with poor hygiene, often causes gastrointestinal or pulmonary symptoms, with imaging fndings such as real-time movement of echogenic defects on ultrasound and ground-glass or alveolar infltrates on CT. Leishmaniasis often presents with nonspecifc fndings, Dengue can cause hepatosplenomegaly, pleural efusions, gallbladder wall edema, and ascites, with severe cases leading to hemorrhagic manifestations or CNS involvement. Chikungunya typically presents with arthralgia, arthritis, and synovitis. Hydatid disease, afecting multiple organs, relies on imaging for diagnosis, with ultrasound, CT, and MRI crucial for identifying cysts and complications. Tuberculosis in children manifests in the CNS as tuberculomas or meningitis. Osteoarticular tuberculosis accounts for 10–20% of extrapulmonary cases, with common presentations including spondylitis, arthritis, and osteomyelitis. We deeply appreciate Dr. Epelman for inspiring this project, the frst to feature exclusively Latin American authors. Her invaluable guidance made this initiative possible. Through this minisymposium, the Sociedad Latinoamericana de Radiología Pediátrica (SLARP) fulflls its mission to promote regional research and share insights on globally relevant yet underexplored topics, engaging readers worldwidesuch as hepatosplenomegaly and lymphadenopathy. Mención de responsabilidad : Carlos F Ugas Charcape, Lina Cadavid, Tatiana Fazecas. Referencia : Pediatr Radiol . 2025 Jan;55(1):64. DOI (Digital Object Identifier) : 10.1007/s00247-024-06125-x PMID : 39644354 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39644354/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Factors associated with development of end stage renal disease during hospitalization in patients with microscopic polyangiitis and granulomatosis with polyangiitis in a population of northwestern Colombia Otros títulos : Factores asociados con el desarrollo de falla renal crónica terminal durante la hospitalización en los pacientes con poliangitis microscópica y granulomatosis con poliangitis en una población del noroccidente colombiano Tipo de documento : documento electrónico Autores : Jhon Edwar García Rueda, Autor ; Cobaleda Cano, Santiago, Autor ; Andrés Felipe Echeverri García, Autor ; Trejos Tenorio, Adriana Margarita, Autor ; Javier Darío Márquez Hernández, Autor ; Luis Fernando Pinto Peñaranda, Autor Fecha de publicación : 2025 Títulos uniformes : Revista Colombiana de Reumatología Idioma : Español (spa) Palabras clave : ANCA; Microscopic polyangiitis; Polyangiitis with granulomatosis; Vasculitis Resumen : Introduction: ANCA vasculitis has been associated with increased morbidity and mortality, high disease burden, and organ damage, especially renal. Objectives: To determine factors associated with end-stage kidney disease at hospital discharge in microscopic polyangiitis and granulomatosis with polyangiitis patients, to characterize our population, hospitalization causes, treatment received, and complications during stay. Materials and methods: Adults with previous or new diagnosis of microscopic polyangiitis and granulomatosis with polyangiitis who required hospitalization between January 01, 2013, and April 30, 2021, were included. Association with end-stage kidney disease development was evaluated by Pearson's Chi2 (?2) or Fisher's test, and Student's t or Mann-Whitney U test according to the nature of the variables. Exploratory multivariate models were made including factors associated with end-stage kidney disease. Results: Forty-three patients were included, microscopic polyangiitis 55.8, and granulomatosis with polyangiitis 44.25. Twelve patients (27.9%) developed early end-stage kidney disease. High blood pressure, high urea nitrogen levels on admission, as well as pulmonary oedema, and Five Factor Score > 1 entailed a higher risk. In contrast, normal kidney function on admission was a protective factor. Rapidly progressive glomerulonephritis and arterial hypertension on admission were associated with end-stage kidney disease. In adjusted exploratory models according to vasculitis type, Birmingham Vasculitis Activity Score, diffuse alveolar haemorrhage, and plasma exchange use were identified as factors to include in multivariate models in multicentre studies. Conclusion: 88% of patients had renal involvement and 27.9% developed end-stage kidney disease. Rapidly progressive glomerulonephritis and arterial hypertension on hospital admission were associated with early development of end-stage kidney disease while normal renal function on admission was a protective factor for this outcome. © 2024 Asociación Colombiana de Reumatología Mención de responsabilidad : Cobaleda Cano, Santiago, Echeverri García, Andrés Felipe, Trejos Tenorio, Adriana Margarita, Márquez Hernández, Javier Darío, García Rueda, Jhon Edwar, Pinto Peñaranda, Luis Fernando Referencia : Revista Colombiana de Reumatología Volume 32, Issue 1, January–March 2025, Pages 16-26 DOI (Digital Object Identifier) : 10.1016/j.rcreu.2023.11.004 Derechos de uso : CC BY-NC-ND En línea : https://www.sciencedirect.com/science/article/abs/pii/S012181232300110X Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Factors associated with development of end stage renal disease during hospitalization in patients with microscopic polyangiitis and granulomatosis with polyangiitis in a population of northwestern Colombia = Factores asociados con el desarrollo de falla renal crónica terminal durante la hospitalización en los pacientes con poliangitis microscópica y granulomatosis con poliangitis en una población del noroccidente colombiano [documento electrónico] / Jhon Edwar García Rueda, Autor ; Cobaleda Cano, Santiago, Autor ; Andrés Felipe Echeverri García, Autor ; Trejos Tenorio, Adriana Margarita, Autor ; Javier Darío Márquez Hernández, Autor ; Luis Fernando Pinto Peñaranda, Autor . - 2025.
Obra : Revista Colombiana de Reumatología
Idioma : Español (spa)
Palabras clave : ANCA; Microscopic polyangiitis; Polyangiitis with granulomatosis; Vasculitis Resumen : Introduction: ANCA vasculitis has been associated with increased morbidity and mortality, high disease burden, and organ damage, especially renal. Objectives: To determine factors associated with end-stage kidney disease at hospital discharge in microscopic polyangiitis and granulomatosis with polyangiitis patients, to characterize our population, hospitalization causes, treatment received, and complications during stay. Materials and methods: Adults with previous or new diagnosis of microscopic polyangiitis and granulomatosis with polyangiitis who required hospitalization between January 01, 2013, and April 30, 2021, were included. Association with end-stage kidney disease development was evaluated by Pearson's Chi2 (?2) or Fisher's test, and Student's t or Mann-Whitney U test according to the nature of the variables. Exploratory multivariate models were made including factors associated with end-stage kidney disease. Results: Forty-three patients were included, microscopic polyangiitis 55.8, and granulomatosis with polyangiitis 44.25. Twelve patients (27.9%) developed early end-stage kidney disease. High blood pressure, high urea nitrogen levels on admission, as well as pulmonary oedema, and Five Factor Score > 1 entailed a higher risk. In contrast, normal kidney function on admission was a protective factor. Rapidly progressive glomerulonephritis and arterial hypertension on admission were associated with end-stage kidney disease. In adjusted exploratory models according to vasculitis type, Birmingham Vasculitis Activity Score, diffuse alveolar haemorrhage, and plasma exchange use were identified as factors to include in multivariate models in multicentre studies. Conclusion: 88% of patients had renal involvement and 27.9% developed end-stage kidney disease. Rapidly progressive glomerulonephritis and arterial hypertension on hospital admission were associated with early development of end-stage kidney disease while normal renal function on admission was a protective factor for this outcome. © 2024 Asociación Colombiana de Reumatología Mención de responsabilidad : Cobaleda Cano, Santiago, Echeverri García, Andrés Felipe, Trejos Tenorio, Adriana Margarita, Márquez Hernández, Javier Darío, García Rueda, Jhon Edwar, Pinto Peñaranda, Luis Fernando Referencia : Revista Colombiana de Reumatología Volume 32, Issue 1, January–March 2025, Pages 16-26 DOI (Digital Object Identifier) : 10.1016/j.rcreu.2023.11.004 Derechos de uso : CC BY-NC-ND En línea : https://www.sciencedirect.com/science/article/abs/pii/S012181232300110X Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Association between inappropriate empirical antimicrobial therapy and mortality in gram-negative bloodstream infections in patients with febrile neutropenia and hematological malignancy Tipo de documento : documento electrónico Autores : Isabel Cristina Ramírez Sánchez, Autor ; Flórez Riaño, Ariel Fernando, Autor ; Rojas Castro, Oscar Julián, Autor ; Ospina, Sigifredo, Autor Fecha de publicación : 2025 Títulos uniformes : Journal of Infection and Chemotherapy Idioma : Español (spa) Idioma original : Inglés (eng) Palabras clave : Bloodstream infection; Carbapenem resistance; Empirical treatment; Febrile neutropenia; Gram-negative bacilli; Inappropriate therapy; Mortality Resumen : Background and objective: Inappropriate initial antimicrobial therapy has been associated with high mortality in patients with gram-negative bacilli bloodstream infections during febrile neutropenia following chemotherapy for hematological malignancies. The aim of this study is to determine this association in our hospital. Methods: A single center, retrospective, cohort study of bloodstream infection due to gram-negative bacilli and febrile neutropenia was conducted. Clinical characteristics, microbiological etiology, antimicrobial resistance profile, empirical and targeted antibiotic therapy, intensive care unit admission, persistent bacteremia and mortality were analyzed. Results: Of the 171 episodes of bloodstream infection due to gram-negative bacilli, empirical antimicrobial therapy was inappropriate in 43 episodes (25.1 %). There was a significant difference in mortality at 7 and 30 days between patients who received appropriate versus inappropriate empirical treatment (4.6 % versus 13.9 %, p = 0.04; 15.6 % versus 32.5 %, p = 0.016). Inappropriate empirical treatment (RR, 2.97 [95 % CI, 1.01–8.74]), shock at the time of febrile neutropenia diagnosis (RR, 6.5 [95 % CI, 1.83–23.05]) carbapenem-resistant microorganism (RR, 3.73 [95 % CI, 1.14–12.24]) and persistent bacteremia (RR, 84.6 [95 % CI, 11.3–629.4]) were associated with an increased mortality at 7 and 30 days. In the multivariate analysis, shock (RR, 4.85 [95 % CI, 2.10–11.65]) was independently associated with increased 30-day mortality, but inappropriate empirical antimicrobial therapy was not an independent prognostic determinant (RR, 1.66 [0.53–4.82]). Conclusion: Shock at the time of febrile neutropenia diagnosis contributes to mortality in patients with gram-negative bacilli bloodstream infection, in this scenario, appropriate empirical antimicrobial therapy should be encouraged. © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control Mención de responsabilidad : Flórez Riaño, Ariel Fernando, Rojas Castro, Oscar Julián, Ospina, Sigifredo, Ramírez-Sánchez, Isabel Cristina Referencia : Revista de Infecciones y Quimioterapia Volumen 31, Número 2 ,Febrero de 2025, 102538 DOI (Digital Object Identifier) : 10.1016/j.jiac.2024.10.006 PMID : 39396607 Derechos de uso : CC BY-NC-ND En línea : https://www.sciencedirect.com/science/article/abs/pii/S1341321X24002794 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Association between inappropriate empirical antimicrobial therapy and mortality in gram-negative bloodstream infections in patients with febrile neutropenia and hematological malignancy [documento electrónico] / Isabel Cristina Ramírez Sánchez, Autor ; Flórez Riaño, Ariel Fernando, Autor ; Rojas Castro, Oscar Julián, Autor ; Ospina, Sigifredo, Autor . - 2025.
Obra : Journal of Infection and Chemotherapy
Idioma : Español (spa) Idioma original : Inglés (eng)
Palabras clave : Bloodstream infection; Carbapenem resistance; Empirical treatment; Febrile neutropenia; Gram-negative bacilli; Inappropriate therapy; Mortality Resumen : Background and objective: Inappropriate initial antimicrobial therapy has been associated with high mortality in patients with gram-negative bacilli bloodstream infections during febrile neutropenia following chemotherapy for hematological malignancies. The aim of this study is to determine this association in our hospital. Methods: A single center, retrospective, cohort study of bloodstream infection due to gram-negative bacilli and febrile neutropenia was conducted. Clinical characteristics, microbiological etiology, antimicrobial resistance profile, empirical and targeted antibiotic therapy, intensive care unit admission, persistent bacteremia and mortality were analyzed. Results: Of the 171 episodes of bloodstream infection due to gram-negative bacilli, empirical antimicrobial therapy was inappropriate in 43 episodes (25.1 %). There was a significant difference in mortality at 7 and 30 days between patients who received appropriate versus inappropriate empirical treatment (4.6 % versus 13.9 %, p = 0.04; 15.6 % versus 32.5 %, p = 0.016). Inappropriate empirical treatment (RR, 2.97 [95 % CI, 1.01–8.74]), shock at the time of febrile neutropenia diagnosis (RR, 6.5 [95 % CI, 1.83–23.05]) carbapenem-resistant microorganism (RR, 3.73 [95 % CI, 1.14–12.24]) and persistent bacteremia (RR, 84.6 [95 % CI, 11.3–629.4]) were associated with an increased mortality at 7 and 30 days. In the multivariate analysis, shock (RR, 4.85 [95 % CI, 2.10–11.65]) was independently associated with increased 30-day mortality, but inappropriate empirical antimicrobial therapy was not an independent prognostic determinant (RR, 1.66 [0.53–4.82]). Conclusion: Shock at the time of febrile neutropenia diagnosis contributes to mortality in patients with gram-negative bacilli bloodstream infection, in this scenario, appropriate empirical antimicrobial therapy should be encouraged. © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control Mención de responsabilidad : Flórez Riaño, Ariel Fernando, Rojas Castro, Oscar Julián, Ospina, Sigifredo, Ramírez-Sánchez, Isabel Cristina Referencia : Revista de Infecciones y Quimioterapia Volumen 31, Número 2 ,Febrero de 2025, 102538 DOI (Digital Object Identifier) : 10.1016/j.jiac.2024.10.006 PMID : 39396607 Derechos de uso : CC BY-NC-ND En línea : https://www.sciencedirect.com/science/article/abs/pii/S1341321X24002794 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Candida tropicalis Invasive Infection in Febrile Neutropenia, a High Mortality Infection Tipo de documento : documento electrónico Autores : Arango, Marcos, Autor ; Ramírez, Isabel C., Autor Fecha de publicación : 2025 Títulos uniformes : Open Forum Infectious Diseases Idioma : Inglés (eng) Resumen : Invasive candidiasis due to species other than Candida albicans emerges as a problem in neutropenic patients receiving antifungal prophylaxis, due to decreased susceptibility to triazoles. Candida tropicalis is the most frequently species in this population and is associated with higher mortality when compared to Candida albicans. The aim of this study is to characterize the neutropenic population with invasive candidiasis and establish differences in outcome of patients with Candida tropicalis infection compared to other Candida species. Characteristics of patients with invasive candidiasis Mención de responsabilidad : Marcos Arango, Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2421 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2421 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2421/7988378?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Candida tropicalis Invasive Infection in Febrile Neutropenia, a High Mortality Infection [documento electrónico] / Arango, Marcos, Autor ; Ramírez, Isabel C., Autor . - 2025.
Obra : Open Forum Infectious Diseases
Idioma : Inglés (eng)
Resumen : Invasive candidiasis due to species other than Candida albicans emerges as a problem in neutropenic patients receiving antifungal prophylaxis, due to decreased susceptibility to triazoles. Candida tropicalis is the most frequently species in this population and is associated with higher mortality when compared to Candida albicans. The aim of this study is to characterize the neutropenic population with invasive candidiasis and establish differences in outcome of patients with Candida tropicalis infection compared to other Candida species. Characteristics of patients with invasive candidiasis Mención de responsabilidad : Marcos Arango, Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2421 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2421 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2421/7988378?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data Tipo de documento : documento electrónico Autores : Parra Izquierdo, Viviana, Autor ; Otero Regino, William, Autor ; Fabián Juliao Baños, Autor ; Frías Ordoñez, Juan Sebastián, Autor ; Ibañez Pinilla, Edgar, Autor ; Gil Parada, Fabio Leonel, Autor ; Marulanda Fernández, Hernando, Autor ; Otero Parra, Lina, Autor ; Otero Ramos, Elder, Autor ; Puentes Manosalva, Fabian Eduardo, Autor ; Guzmán Rojas, Gerardo Andrés, Autor ; Ernest Suarez, Kenneth, Autor ; Villa Ovalles, Keyla, Autor ; Paredes Mendez, Juan Eloy, Autor ; Jara Alba, María Luisa, Autor ; Andrade Zamora, David, Autor ; Ardila Báez, Manuel Alonso, Autor ; Floréz Sarmiento, Cristian, Autor ; Veitia, Guillermo, Autor ; Sánchez, Abel, Autor ; Arango Molano, Lazaro Antonio, Autor ; Fluxa, Fernando, Autor ; Freitas Queiroz, Natália Sousa, Autor ; Serrano, Mariastella, Autor Fecha de publicación : 2025 Títulos uniformes : Crohn's and Colitis 360 Idioma : Inglés (eng) Palabras clave : (MeSH): inflammatory bowel diseases; colitis; colonic neoplasms; colonoscopy; prognosis; ulcerative Resumen : Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology. Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity. Surveillance colonoscopies were performed according to available technology. Risk factors for dysplasia detection were analyzed. Results: One hundred and forty-four patients, 55.5% women, mean age 47.3 (range 17.1 to 90; SD 15.64) years and mean duration of disease 12.71 (range 0.64 to 57.13; SD 8.08) years. Forty-nine lesions were identified, 18 corresponded to dysplasia. The detection rate of dysplasia per lesion and per procedure was 36.7% and 12.5%, respectively. By logistic regression analysis, the duration of disease (OR 1.12;95%CI:1.047 to 1.215, P = .002) and the presence of post-inflammatory polyps (OR 3.4;95%CI:1.11 to 10.36, P = .031) were risk factors for higher detection of dysplasia. Digital chromoendoscopy was associated with greater detection of dysplasia (OR 4.99, 95%CI: 1.092 to 22.864, P = .038). Conclusions: In our region, the duration of disease and the presence of post-inflammatory polyps were the factors with the highest association for dysplasia detection, and digital chromoendoscopy with directed biopsies was the technique of choice. The implementation of a specific surveillance program in colonoscopy in IBD is an effective strategy to achieve high detection rates. © 2025 The Author(s). Mención de responsabilidad : Parra-Izquierdo, Viviana, Otero-Regino, William, Juliao-Baños, Fabian, Frías-Ordoñez, Juan Sebastián, Ibañez-Pinilla, Edgar, Gil-Parada, Fabio Leonel, Marulanda-Fernández, Hernando, Otero-Parra, Lina, Otero-Ramos, Elder, Puentes-Manosalva, Fabian Eduardo, Guzmán Rojas, Gerardo Andres, Ernest-Suárez, Kenneth, Villa-Ovalles, Keyla, Paredes-Mendez, Juan Eloy, Jara-Alba, María Luisa, Andrade-Zamora, David, Ardila-Báez, Manuel Alonso, Flórez-Sarmiento, Cristian, Veitia, Guillermo, Sánchez, Abel, Arango-Molano, Lazaro Antonio, Fluxa, Fernando, Freitas Queiroz, Natália Sousa, Serrano, Mariastella Referencia : Crohns Colitis 360 . 2025 Jan 14;7(1):otae081 DOI (Digital Object Identifier) : 10.1093/crocol/otae081 PMID : 39834355 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39834355/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data [documento electrónico] / Parra Izquierdo, Viviana, Autor ; Otero Regino, William, Autor ; Fabián Juliao Baños, Autor ; Frías Ordoñez, Juan Sebastián, Autor ; Ibañez Pinilla, Edgar, Autor ; Gil Parada, Fabio Leonel, Autor ; Marulanda Fernández, Hernando, Autor ; Otero Parra, Lina, Autor ; Otero Ramos, Elder, Autor ; Puentes Manosalva, Fabian Eduardo, Autor ; Guzmán Rojas, Gerardo Andrés, Autor ; Ernest Suarez, Kenneth, Autor ; Villa Ovalles, Keyla, Autor ; Paredes Mendez, Juan Eloy, Autor ; Jara Alba, María Luisa, Autor ; Andrade Zamora, David, Autor ; Ardila Báez, Manuel Alonso, Autor ; Floréz Sarmiento, Cristian, Autor ; Veitia, Guillermo, Autor ; Sánchez, Abel, Autor ; Arango Molano, Lazaro Antonio, Autor ; Fluxa, Fernando, Autor ; Freitas Queiroz, Natália Sousa, Autor ; Serrano, Mariastella, Autor . - 2025.
Obra : Crohn's and Colitis 360
Idioma : Inglés (eng)
Palabras clave : (MeSH): inflammatory bowel diseases; colitis; colonic neoplasms; colonoscopy; prognosis; ulcerative Resumen : Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology. Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity. Surveillance colonoscopies were performed according to available technology. Risk factors for dysplasia detection were analyzed. Results: One hundred and forty-four patients, 55.5% women, mean age 47.3 (range 17.1 to 90; SD 15.64) years and mean duration of disease 12.71 (range 0.64 to 57.13; SD 8.08) years. Forty-nine lesions were identified, 18 corresponded to dysplasia. The detection rate of dysplasia per lesion and per procedure was 36.7% and 12.5%, respectively. By logistic regression analysis, the duration of disease (OR 1.12;95%CI:1.047 to 1.215, P = .002) and the presence of post-inflammatory polyps (OR 3.4;95%CI:1.11 to 10.36, P = .031) were risk factors for higher detection of dysplasia. Digital chromoendoscopy was associated with greater detection of dysplasia (OR 4.99, 95%CI: 1.092 to 22.864, P = .038). Conclusions: In our region, the duration of disease and the presence of post-inflammatory polyps were the factors with the highest association for dysplasia detection, and digital chromoendoscopy with directed biopsies was the technique of choice. The implementation of a specific surveillance program in colonoscopy in IBD is an effective strategy to achieve high detection rates. © 2025 The Author(s). Mención de responsabilidad : Parra-Izquierdo, Viviana, Otero-Regino, William, Juliao-Baños, Fabian, Frías-Ordoñez, Juan Sebastián, Ibañez-Pinilla, Edgar, Gil-Parada, Fabio Leonel, Marulanda-Fernández, Hernando, Otero-Parra, Lina, Otero-Ramos, Elder, Puentes-Manosalva, Fabian Eduardo, Guzmán Rojas, Gerardo Andres, Ernest-Suárez, Kenneth, Villa-Ovalles, Keyla, Paredes-Mendez, Juan Eloy, Jara-Alba, María Luisa, Andrade-Zamora, David, Ardila-Báez, Manuel Alonso, Flórez-Sarmiento, Cristian, Veitia, Guillermo, Sánchez, Abel, Arango-Molano, Lazaro Antonio, Fluxa, Fernando, Freitas Queiroz, Natália Sousa, Serrano, Mariastella Referencia : Crohns Colitis 360 . 2025 Jan 14;7(1):otae081 DOI (Digital Object Identifier) : 10.1093/crocol/otae081 PMID : 39834355 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39834355/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : CMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia Tipo de documento : documento electrónico Autores : Laura Fernanda Niño Serna, Autor ; Alejandro Díaz Díaz, Autor ; Mónica Rosa Trujillo Honeysberg, Autor ; Natalia Builes R., Autor ; Arias, Andrés, Autor ; Aristizábal, Beatriz H, Autor Fecha de publicación : 2025 Títulos uniformes : Pediatric Transplantation Idioma : Inglés (eng) Palabras clave : CMV; cytomegalovirus infection; haploidentical; hematopoietic stem cell transplantation; pediatrics; transplantation Resumen : Introduction: Cytomegalovirus (CMV) infection is a frequent complication among hematopoietic stem cell transplant (HSCT) recipients. Data regarding CMV reactivation in children in underdeveloped countries is scarce. This is especially notable considering the increasing utilization of haploidentical-related HSCT with the post-transplant cyclophosphamide platform. This study aimed to describe the incidence, clinical characteristics, and evolution of children with CMV reactivation after HSCT and the possible impact of unmanipulated stem cells with PTCy for GvHD prophylaxis. Methods: Retrospective cohort study of children undergoing hematopoietic stem cell transplantation from January 2012 to June 2022. Baseline characteristics and the clinical course were described. Duration of treatment, initial viral load, and time to clearance of DNAemia by type of transplant were compared using the Kruskal-Wallis test. Survival analysis was performed with the Kaplan–Meier method and log-rank test. All statistical analysis was performed using SPSS software, version 20.0. Results: One hundred sixty-six children were included. Among them, 87% of recipients and 88% of donors were CMV positive. The cumulative incidence of cytomegalovirus DNAemia was 28% at 100 days post-transplantation. There were no differences between different donor types. Overall survival at 1 year was 60%, and non-relapse mortality was observed in 28%. CMV reactivation did not appear to negatively impact 1-year overall survival (OS). Conclusions: Our study found no differences in CMV reactivation rates, treatment duration, viral clearance times, co-infections, or 1-year overall survival across different HSCT donor types. Studies are needed to establish more precise criteria for monitoring recipients, particularly in regions where unmanipulated stem cells with PTCy for GvHD prophylaxis are increasing. © 2025 Wiley Periodicals LLC. Mención de responsabilidad : Arias, Andres, Builes, Natalia, Niño-Serna, Laura, Diaz, Alejandro, Aristizabal, Beatriz H., Trujillo, Monica. Referencia : Pediatr Transplant . 2025 Feb;29(1):e70033 DOI (Digital Object Identifier) : 10.1111/petr.70033 PMID : 39837777 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39837777/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis CMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia [documento electrónico] / Laura Fernanda Niño Serna, Autor ; Alejandro Díaz Díaz, Autor ; Mónica Rosa Trujillo Honeysberg, Autor ; Natalia Builes R., Autor ; Arias, Andrés, Autor ; Aristizábal, Beatriz H, Autor . - 2025.
Obra : Pediatric Transplantation
Idioma : Inglés (eng)
Palabras clave : CMV; cytomegalovirus infection; haploidentical; hematopoietic stem cell transplantation; pediatrics; transplantation Resumen : Introduction: Cytomegalovirus (CMV) infection is a frequent complication among hematopoietic stem cell transplant (HSCT) recipients. Data regarding CMV reactivation in children in underdeveloped countries is scarce. This is especially notable considering the increasing utilization of haploidentical-related HSCT with the post-transplant cyclophosphamide platform. This study aimed to describe the incidence, clinical characteristics, and evolution of children with CMV reactivation after HSCT and the possible impact of unmanipulated stem cells with PTCy for GvHD prophylaxis. Methods: Retrospective cohort study of children undergoing hematopoietic stem cell transplantation from January 2012 to June 2022. Baseline characteristics and the clinical course were described. Duration of treatment, initial viral load, and time to clearance of DNAemia by type of transplant were compared using the Kruskal-Wallis test. Survival analysis was performed with the Kaplan–Meier method and log-rank test. All statistical analysis was performed using SPSS software, version 20.0. Results: One hundred sixty-six children were included. Among them, 87% of recipients and 88% of donors were CMV positive. The cumulative incidence of cytomegalovirus DNAemia was 28% at 100 days post-transplantation. There were no differences between different donor types. Overall survival at 1 year was 60%, and non-relapse mortality was observed in 28%. CMV reactivation did not appear to negatively impact 1-year overall survival (OS). Conclusions: Our study found no differences in CMV reactivation rates, treatment duration, viral clearance times, co-infections, or 1-year overall survival across different HSCT donor types. Studies are needed to establish more precise criteria for monitoring recipients, particularly in regions where unmanipulated stem cells with PTCy for GvHD prophylaxis are increasing. © 2025 Wiley Periodicals LLC. Mención de responsabilidad : Arias, Andres, Builes, Natalia, Niño-Serna, Laura, Diaz, Alejandro, Aristizabal, Beatriz H., Trujillo, Monica. Referencia : Pediatr Transplant . 2025 Feb;29(1):e70033 DOI (Digital Object Identifier) : 10.1111/petr.70033 PMID : 39837777 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39837777/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Spectrum of Invasive Mold Sinusitis in Adults with Hematological Malignancies Tipo de documento : documento electrónico Autores : Ramírez, Isabel C., Autor Fecha de publicación : 2025 Títulos uniformes : Open Forum Infectious Diseases Idioma : Inglés (eng) Resumen : Invasive mold sinusitis (IMS) occurs exclusively in immunocompromised patients. In patients with hematologic malignancies, it is associated with mortality and may affect cancer-related survival by causing delay of the chemotherapy regimen. Clinical characteristics of patients with IMS Mención de responsabilidad : Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2423 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2423 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2423/7988374?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Spectrum of Invasive Mold Sinusitis in Adults with Hematological Malignancies [documento electrónico] / Ramírez, Isabel C., Autor . - 2025.
Obra : Open Forum Infectious Diseases
Idioma : Inglés (eng)
Resumen : Invasive mold sinusitis (IMS) occurs exclusively in immunocompromised patients. In patients with hematologic malignancies, it is associated with mortality and may affect cancer-related survival by causing delay of the chemotherapy regimen. Clinical characteristics of patients with IMS Mención de responsabilidad : Isabel C Ramirez Referencia : Open Forum Infectious Diseases, Volume 12, Issue Supplement_1, February 2025, ofae631.2423 DOI (Digital Object Identifier) : 10.1093/ofid/ofae631.2423 Derechos de uso : CC BY-NC-ND En línea : https://academic.oup.com/ofid/article/12/Supplement_1/ofae631.2423/7988374?login [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : Primary Thrombotic Microangiopathy in Pediatric Patients Tipo de documento : documento electrónico Autores : Pamplona Sierra, Ana Paulina, Autor ; Martínez Sánchez, Lina María, Autor ; Vergara Yánez, Daniela, Autor ; Franco Hincapié, Liliana, Autor ; Baquero Rodríguez, Richard, Autor Fecha de publicación : 2024 Títulos uniformes : Global Pediatric Health Idioma : Inglés (eng) Palabras clave : purpura thrombocytopenic ADAMTS13 protein acute kidney injury hemolytic-uremic syndrome Resumen : Background. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Methodology. A retrospective study that included patients younger than 18?years diagnosed with primary thrombotic microangiopathy between 2011 and 2021. Results. Thirty patients were included, of which 63% corresponded to a hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, and 30% to the atypical hemolytic uremic syndrome. The median age was 2.8?years and female sex predominated at 57%. On admission to the emergency room, fever and fatigue were the most frequent symptoms (93%), followed by oliguria and anuria (80%). 48% of patients received hemodialysis during their care. Mortality was estimated at 13%. Conclusion. This study constitutes the largest series of primary thrombotic microangiopathy in the pediatric population of Latin America, where the etiological and clinical behavior of this condition is described. Mención de responsabilidad : Andrés David Aranzazu Ceballos, Ana Paulina Pamplona Sierra, Daniela Vergara Yánez, Liliana Franco Hincapié, Richard Baquero Rodriguez. Referencia : Global Pediatric HealthVolume 11, 2024 DOI (Digital Object Identifier) : 10.1177/2333794X241307535 Derechos de uso : CC BY-NC En línea : https://journals.sagepub.com/doi/full/10.1177/2333794X241307535 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Primary Thrombotic Microangiopathy in Pediatric Patients [documento electrónico] / Pamplona Sierra, Ana Paulina, Autor ; Martínez Sánchez, Lina María, Autor ; Vergara Yánez, Daniela, Autor ; Franco Hincapié, Liliana, Autor ; Baquero Rodríguez, Richard, Autor . - 2024.
Obra : Global Pediatric Health
Idioma : Inglés (eng)
Palabras clave : purpura thrombocytopenic ADAMTS13 protein acute kidney injury hemolytic-uremic syndrome Resumen : Background. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Methodology. A retrospective study that included patients younger than 18?years diagnosed with primary thrombotic microangiopathy between 2011 and 2021. Results. Thirty patients were included, of which 63% corresponded to a hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, and 30% to the atypical hemolytic uremic syndrome. The median age was 2.8?years and female sex predominated at 57%. On admission to the emergency room, fever and fatigue were the most frequent symptoms (93%), followed by oliguria and anuria (80%). 48% of patients received hemodialysis during their care. Mortality was estimated at 13%. Conclusion. This study constitutes the largest series of primary thrombotic microangiopathy in the pediatric population of Latin America, where the etiological and clinical behavior of this condition is described. Mención de responsabilidad : Andrés David Aranzazu Ceballos, Ana Paulina Pamplona Sierra, Daniela Vergara Yánez, Liliana Franco Hincapié, Richard Baquero Rodriguez. Referencia : Global Pediatric HealthVolume 11, 2024 DOI (Digital Object Identifier) : 10.1177/2333794X241307535 Derechos de uso : CC BY-NC En línea : https://journals.sagepub.com/doi/full/10.1177/2333794X241307535 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002314 AC-2024-169 Archivo digital Producción Científica Artículos científicos Disponible
