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Effect and associated factors of a clinical pharmacy model in the incidence of medication errors (EACPharModel) in the Hospital Pablo Tobón Uribe: study protocol for a stepped wedge randomized controlled trial (NCT03338725) / Juan Pablo Botero Aguirre ; Andrés Felipe Valencia Quintero ; Natalia Andrea Ortíz Cano
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Título : Effect and associated factors of a clinical pharmacy model in the incidence of medication errors (EACPharModel) in the Hospital Pablo Tobón Uribe: study protocol for a stepped wedge randomized controlled trial (NCT03338725) Tipo de documento : documento electrónico Autores : Juan Pablo Botero Aguirre, ; Andrés Felipe Valencia Quintero, ; Natalia Andrea Ortíz Cano, Fecha de publicación : 2020 Títulos uniformes : Trials Idioma : Inglés (eng) Palabras clave : Medication errors Drug-related problems Pharmacy service Hospital (clinical pharmacy services) Pharmacists Resumen : Background: According to WHO, medication error (ME) is a subject that requires attention at all levels of care to reduce severe and preventable damage related to medication use. Clinical pharmacy practice standards have been proposed around the world so that the pharmacist, as part of a multidisciplinary health team, can help improve patient safety; however, further evidence derived from adequate studies is needed to demonstrate this. This study aims to assess the effect of a clinical pharmacy practice model (CPPM) in preventing MEs associated with the medication use process. Methods: A prospective, stepped-wedge, cluster-randomized, controlled trial with a duration of 14 months will be performed to compare the effect of a CPPM along with the usual care process of patients in the Pablo Tobón Uribe Hospital (Medellin, Colombia). The study is designed as a cluster-randomized controlled trial, involving five hospital wards (clusters) and 720 patients. Medical wards are allocated to interventions using a stepped-wedge design. Clusters are initially assigned to the control group. After a 2-month observation period, hospital clusters were randomly allocated to the intervention group. Study outcomes will be assessed at baseline and at 2, 4, 6, 8, 10, and 12 months after randomization. The primary outcome will be to assess the effect of a CPPM on the incidence of medication errors associated with the medication use process. Drug-related problems and factors that contribute to the occurrence of MEs will be assessed as secondary outcomes. Statistical analyses will be performed using a mixed model, with the treatment group and time as fixed effects and the clustering structure as a random effect. Statistical analysis will be performed using Pearson chi-square tests and Student's t-tests, and a P value Mención de responsabilidad : J Granados, A Salazar-Ospina, J P Botero-Aguirre, A F Valencia-Quintero, N Ortiz, P Amariles Referencia : Trials. 2020;21(1):26. DOI (Digital Object Identifier) : 10.1186/s13063-019-3945-8 PMID : 31907009 Derechos de uso : CC BY En línea : https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3945-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5074 Effect and associated factors of a clinical pharmacy model in the incidence of medication errors (EACPharModel) in the Hospital Pablo Tobón Uribe: study protocol for a stepped wedge randomized controlled trial (NCT03338725) [documento electrónico] / Juan Pablo Botero Aguirre, ; Andrés Felipe Valencia Quintero, ; Natalia Andrea Ortíz Cano, . - 2020.
Obra : Trials
Idioma : Inglés (eng)
Palabras clave : Medication errors Drug-related problems Pharmacy service Hospital (clinical pharmacy services) Pharmacists Resumen : Background: According to WHO, medication error (ME) is a subject that requires attention at all levels of care to reduce severe and preventable damage related to medication use. Clinical pharmacy practice standards have been proposed around the world so that the pharmacist, as part of a multidisciplinary health team, can help improve patient safety; however, further evidence derived from adequate studies is needed to demonstrate this. This study aims to assess the effect of a clinical pharmacy practice model (CPPM) in preventing MEs associated with the medication use process. Methods: A prospective, stepped-wedge, cluster-randomized, controlled trial with a duration of 14 months will be performed to compare the effect of a CPPM along with the usual care process of patients in the Pablo Tobón Uribe Hospital (Medellin, Colombia). The study is designed as a cluster-randomized controlled trial, involving five hospital wards (clusters) and 720 patients. Medical wards are allocated to interventions using a stepped-wedge design. Clusters are initially assigned to the control group. After a 2-month observation period, hospital clusters were randomly allocated to the intervention group. Study outcomes will be assessed at baseline and at 2, 4, 6, 8, 10, and 12 months after randomization. The primary outcome will be to assess the effect of a CPPM on the incidence of medication errors associated with the medication use process. Drug-related problems and factors that contribute to the occurrence of MEs will be assessed as secondary outcomes. Statistical analyses will be performed using a mixed model, with the treatment group and time as fixed effects and the clustering structure as a random effect. Statistical analysis will be performed using Pearson chi-square tests and Student's t-tests, and a P value Mención de responsabilidad : J Granados, A Salazar-Ospina, J P Botero-Aguirre, A F Valencia-Quintero, N Ortiz, P Amariles Referencia : Trials. 2020;21(1):26. DOI (Digital Object Identifier) : 10.1186/s13063-019-3945-8 PMID : 31907009 Derechos de uso : CC BY En línea : https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3945-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5074 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001304 AC-2020-008 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-008.pdfAdobe Acrobat PDFDisseminated Cryptococcosis After Liver Transplant: A Case Report / Juan Ignacio Marín Zuluaga ; Octavio Germán Muñoz Maya ; Óscar Mauricio Santos Sánchez ; Isabel Cristina Ramírez Sánchez ; Juan Carlos Restrepo Gutiérrez
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Título : Disseminated Cryptococcosis After Liver Transplant: A Case Report Tipo de documento : documento electrónico Autores : Juan Ignacio Marín Zuluaga, ; Octavio Germán Muñoz Maya, ; Óscar Mauricio Santos Sánchez, ; Isabel Cristina Ramírez Sánchez, ; Juan Carlos Restrepo Gutiérrez, Fecha de publicación : 2020 Títulos uniformes : Experimental and Clinical Transplantation Idioma : Inglés (eng) Palabras clave : Cryptococcus neoformans Joint pain Liver cirrhosis Resumen : Cryptococcosis is an opportunistic infection caused by the Basidiomycota Cryptococcus neoformans (Cryptococcus gattii), which affects immunosuppressed patients and less frequently immunocompetent patients. Solid-organ transplant recipients are a particularly high-risk group, depending on the net state of immunosuppression. In these patients, the infection usually appears after the first year after transplant, although it may occur earlier in liver transplant recipients. In most cases, the infection is secondary to the reactivation of a latent infection, although it may be due to an unidentified pretransplant infection by primary infection. Less frequently, it may be transmitted by the graft. The lung and central nervous system are most frequently involved. Extrapulmonary involvement is seen in 75% of the cases, and disseminated disease occurs in 61%, with mortality ranging from 17% to 50% when the central nervous system is involved. Here, we report a case of disseminated cryptococcosis (lymphadenitis, meningitis, pulmonary nodules, and possibly sacroiliitis) in a patient after liver transplant, with good clinical and micro-biological outcomes and without relapse. Mención de responsabilidad : Gabriel Sebastián Díaz-Ramírez, Omar Yesid Martínez-Casas, Juan Ignacio Marín-Zuluaga, Octavio Muñoz-Maya, Óscar Santos-Sánchez, Isabel Cristina Ramírez, Juan Carlos Restrepo-Gutiérrez Referencia : Exp Clin Transplant. 2020 Jun;18(3):402-406. DOI (Digital Object Identifier) : 10.6002/ect.2018.0051 PMID : 30696395 En línea : http://www.ectrx.org/forms/ectrxcontentshow.php?doi_id=10.6002/ect.2018.0051 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5106 Disseminated Cryptococcosis After Liver Transplant: A Case Report [documento electrónico] / Juan Ignacio Marín Zuluaga, ; Octavio Germán Muñoz Maya, ; Óscar Mauricio Santos Sánchez, ; Isabel Cristina Ramírez Sánchez, ; Juan Carlos Restrepo Gutiérrez, . - 2020.
Obra : Experimental and Clinical Transplantation
Idioma : Inglés (eng)
Palabras clave : Cryptococcus neoformans Joint pain Liver cirrhosis Resumen : Cryptococcosis is an opportunistic infection caused by the Basidiomycota Cryptococcus neoformans (Cryptococcus gattii), which affects immunosuppressed patients and less frequently immunocompetent patients. Solid-organ transplant recipients are a particularly high-risk group, depending on the net state of immunosuppression. In these patients, the infection usually appears after the first year after transplant, although it may occur earlier in liver transplant recipients. In most cases, the infection is secondary to the reactivation of a latent infection, although it may be due to an unidentified pretransplant infection by primary infection. Less frequently, it may be transmitted by the graft. The lung and central nervous system are most frequently involved. Extrapulmonary involvement is seen in 75% of the cases, and disseminated disease occurs in 61%, with mortality ranging from 17% to 50% when the central nervous system is involved. Here, we report a case of disseminated cryptococcosis (lymphadenitis, meningitis, pulmonary nodules, and possibly sacroiliitis) in a patient after liver transplant, with good clinical and micro-biological outcomes and without relapse. Mención de responsabilidad : Gabriel Sebastián Díaz-Ramírez, Omar Yesid Martínez-Casas, Juan Ignacio Marín-Zuluaga, Octavio Muñoz-Maya, Óscar Santos-Sánchez, Isabel Cristina Ramírez, Juan Carlos Restrepo-Gutiérrez Referencia : Exp Clin Transplant. 2020 Jun;18(3):402-406. DOI (Digital Object Identifier) : 10.6002/ect.2018.0051 PMID : 30696395 En línea : http://www.ectrx.org/forms/ectrxcontentshow.php?doi_id=10.6002/ect.2018.0051 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5106 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001336 AC-2020-040 Archivo digital Producción Científica Artículos científicos Disponible Meta-analysis of hematopoietic stem cell transplantation in major histocompatibility complex class II deficiency / Andrés Felipe Escobar González
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Título : Meta-analysis of hematopoietic stem cell transplantation in major histocompatibility complex class II deficiency Tipo de documento : documento electrónico Autores : Andrés Felipe Escobar González, Fecha de publicación : 2020 Títulos uniformes : Pediatric Transplantation Idioma : Inglés (eng) Palabras clave : hematopoietic stem cell transplant major histocompatibility complex class II deficiency primary immunodeficiency Resumen : Major histocompatibility complex class II deficiency is a rare case of PID. Specific recommendations for hematopoietic stem cell transplant, the only curative treatment option, are still lacking. This meta‐analysis aims to identify the factors associated with better prognosis in these patients. Thirteen articles reporting 63 patients with major histocompatibility complex class II deficiency that underwent hematopoietic stem cell transplant were included. The median age for hematopoietic stem cell transplant was 18 months. The most common source of transplant was bone marrow, with alternative sources as umbilical cord blood emerging during recent years. The highest proportion of engraftment was seen with umbilical cord. Engraftment was higher in patients with matched donors, with better overall survival in patients with reduced‐intensity conditioning. Graft‐vs‐host disease developed in 65% of the patients, with grades I‐II being the most frequently encountered. There was a higher mortality in patients with myeloablative conditioning and no engraftment. There was an inverse correlation between survival and stage of graft‐vs‐host disease. The main cause of mortality was infectious disease, mostly secondary to viral infections. Ideally, matched grafts should be used, and reduced‐intensity conditioning should be considered to reduce early post‐transplant complications. GVHD and viral prophylaxis are fundamental. Mención de responsabilidad : Lina Maria Castano‐Jaramillo, Jose Bareño‐Silva, Santiago Tobon, Andres Felipe Escobar‐Gonzalez Referencia : Pediatr Transplant. 2020 Sep;24(6):e13774. DOI (Digital Object Identifier) : 10.1111/petr.13774 PMID : 32678504 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/petr.13774 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5138 Meta-analysis of hematopoietic stem cell transplantation in major histocompatibility complex class II deficiency [documento electrónico] / Andrés Felipe Escobar González, . - 2020.
Obra : Pediatric Transplantation
Idioma : Inglés (eng)
Palabras clave : hematopoietic stem cell transplant major histocompatibility complex class II deficiency primary immunodeficiency Resumen : Major histocompatibility complex class II deficiency is a rare case of PID. Specific recommendations for hematopoietic stem cell transplant, the only curative treatment option, are still lacking. This meta‐analysis aims to identify the factors associated with better prognosis in these patients. Thirteen articles reporting 63 patients with major histocompatibility complex class II deficiency that underwent hematopoietic stem cell transplant were included. The median age for hematopoietic stem cell transplant was 18 months. The most common source of transplant was bone marrow, with alternative sources as umbilical cord blood emerging during recent years. The highest proportion of engraftment was seen with umbilical cord. Engraftment was higher in patients with matched donors, with better overall survival in patients with reduced‐intensity conditioning. Graft‐vs‐host disease developed in 65% of the patients, with grades I‐II being the most frequently encountered. There was a higher mortality in patients with myeloablative conditioning and no engraftment. There was an inverse correlation between survival and stage of graft‐vs‐host disease. The main cause of mortality was infectious disease, mostly secondary to viral infections. Ideally, matched grafts should be used, and reduced‐intensity conditioning should be considered to reduce early post‐transplant complications. GVHD and viral prophylaxis are fundamental. Mención de responsabilidad : Lina Maria Castano‐Jaramillo, Jose Bareño‐Silva, Santiago Tobon, Andres Felipe Escobar‐Gonzalez Referencia : Pediatr Transplant. 2020 Sep;24(6):e13774. DOI (Digital Object Identifier) : 10.1111/petr.13774 PMID : 32678504 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/petr.13774 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5138 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001398 AC-2020-075 Archivo digital Producción Científica Artículos científicos Disponible Chylothorax as an Initial Manifestation of Waldenström macroglobulinemia / Andrés Zerrate Misas ; Kenny Mauricio Gálvez Cárdenas ; Juan David Ramírez Quintero
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Título : Chylothorax as an Initial Manifestation of Waldenström macroglobulinemia Tipo de documento : documento electrónico Autores : Andrés Zerrate Misas, ; Kenny Mauricio Gálvez Cárdenas, ; Juan David Ramírez Quintero, Fecha de publicación : 2020 Títulos uniformes : Cureus Idioma : Inglés (eng) Palabras clave : chylothorax waldenström macroglobulinemia Resumen : Waldenström macroglobulinemia (WM) is an uncommon disease whose most common presenting features are anemia, hyperviscosity-related symptoms, B symptoms, bleeding, and neurological symptoms. Pulmonary compromise is rare, and there are a few cases reported of chylothorax as a manifestation of Waldenström macroglobulinemia. We present the case of a patient who presented with a refractory chylothorax as the initial manifestation of Waldenström macroglobulinemia. Mención de responsabilidad : Natalia Rodriguez Botero, Andres Zerrate Misas, Kenny Mauricio Galvez Cardenas, Juan David Ramirez Quintero Referencia : Cureus. 2020 Apr 6;12(4):e7566. DOI (Digital Object Identifier) : 10.7759/cureus.7566 PMID : 32382468 Derechos de uso : CC BY En línea : https://www.cureus.com/articles/25255-chylothorax-as-an-initial-manifestation-of [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5097 Chylothorax as an Initial Manifestation of Waldenström macroglobulinemia [documento electrónico] / Andrés Zerrate Misas, ; Kenny Mauricio Gálvez Cárdenas, ; Juan David Ramírez Quintero, . - 2020.
Obra : Cureus
Idioma : Inglés (eng)
Palabras clave : chylothorax waldenström macroglobulinemia Resumen : Waldenström macroglobulinemia (WM) is an uncommon disease whose most common presenting features are anemia, hyperviscosity-related symptoms, B symptoms, bleeding, and neurological symptoms. Pulmonary compromise is rare, and there are a few cases reported of chylothorax as a manifestation of Waldenström macroglobulinemia. We present the case of a patient who presented with a refractory chylothorax as the initial manifestation of Waldenström macroglobulinemia. Mención de responsabilidad : Natalia Rodriguez Botero, Andres Zerrate Misas, Kenny Mauricio Galvez Cardenas, Juan David Ramirez Quintero Referencia : Cureus. 2020 Apr 6;12(4):e7566. DOI (Digital Object Identifier) : 10.7759/cureus.7566 PMID : 32382468 Derechos de uso : CC BY En línea : https://www.cureus.com/articles/25255-chylothorax-as-an-initial-manifestation-of [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5097 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001327 AC-2020-031 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-031.pdfAdobe Acrobat PDFDiaphragm-sparing brachial plexus blocks: a focused review of current evidence and their role during the COVID-19 pandemic / Laura Girón Arango
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Título : Diaphragm-sparing brachial plexus blocks: a focused review of current evidence and their role during the COVID-19 pandemic Tipo de documento : documento electrónico Autores : Laura Girón Arango, Fecha de publicación : 2020 Títulos uniformes : Current Opinion in Anaesthesiology Idioma : Inglés (eng) Palabras clave : brachial plexus COVID-19 diaphragm-sparing nerve block phrenic nerve regional anesthesia Resumen : Purpose of review: Given that COVID-19 can severely impair lung function, regional anesthesia techniques avoiding phrenic nerve paralysis are relevant in the anesthetic management of suspected/confirmed COVID-19 patients requiring shoulder and clavicle surgical procedures. The objective of this review is to provide an overview of recently published studies examining ultrasound-guided diaphragm-sparing regional anesthesia techniques for the brachial plexus (BP) to favor their preferent use in patients at risk of respiratory function compromise. Recent findings: In the last 18 months, study findings on various diaphragm-sparing regional anesthesia techniques have demonstrated comparable block analgesic effectivity with a variable extent of phrenic nerve paralysis. The impact of hemi-diaphragmatic function impairment on clinical outcomes is yet to be established. Summary: Existing diaphragm-sparing brachial plexus regional anesthesia techniques used for shoulder and clavicle surgery may help minimize pulmonary complications by preserving lung function, especially in patients prone to respiratory compromise. Used as an anesthetic technique, they can reduce the risk of exposure of healthcare teams to aerosol-generating medical procedures (AGMPs), albeit posing an increased risk for hemi-diaphragmatic paralysis. Reducing the incidence of phrenic nerve involvement and obtaining opioid-sparing analgesia without jeopardizing efficacy should be prioritized goals of regional anesthesia practice during the COVID-19 pandemic. Mención de responsabilidad : Cubillos, Javier; Girón-Arango, Laura; Muñoz-Leyva, Felipe Referencia : Curr Opin Anaesthesiol. 2020 Oct;33(5):685-691. DOI (Digital Object Identifier) : 10.1097/ACO.0000000000000911 PMID : 32826625 En línea : https://journals.lww.com/co-anesthesiology/Abstract/2020/10000/Diaphragm_sparing [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5129 Diaphragm-sparing brachial plexus blocks: a focused review of current evidence and their role during the COVID-19 pandemic [documento electrónico] / Laura Girón Arango, . - 2020.
Obra : Current Opinion in Anaesthesiology
Idioma : Inglés (eng)
Palabras clave : brachial plexus COVID-19 diaphragm-sparing nerve block phrenic nerve regional anesthesia Resumen : Purpose of review: Given that COVID-19 can severely impair lung function, regional anesthesia techniques avoiding phrenic nerve paralysis are relevant in the anesthetic management of suspected/confirmed COVID-19 patients requiring shoulder and clavicle surgical procedures. The objective of this review is to provide an overview of recently published studies examining ultrasound-guided diaphragm-sparing regional anesthesia techniques for the brachial plexus (BP) to favor their preferent use in patients at risk of respiratory function compromise. Recent findings: In the last 18 months, study findings on various diaphragm-sparing regional anesthesia techniques have demonstrated comparable block analgesic effectivity with a variable extent of phrenic nerve paralysis. The impact of hemi-diaphragmatic function impairment on clinical outcomes is yet to be established. Summary: Existing diaphragm-sparing brachial plexus regional anesthesia techniques used for shoulder and clavicle surgery may help minimize pulmonary complications by preserving lung function, especially in patients prone to respiratory compromise. Used as an anesthetic technique, they can reduce the risk of exposure of healthcare teams to aerosol-generating medical procedures (AGMPs), albeit posing an increased risk for hemi-diaphragmatic paralysis. Reducing the incidence of phrenic nerve involvement and obtaining opioid-sparing analgesia without jeopardizing efficacy should be prioritized goals of regional anesthesia practice during the COVID-19 pandemic. Mención de responsabilidad : Cubillos, Javier; Girón-Arango, Laura; Muñoz-Leyva, Felipe Referencia : Curr Opin Anaesthesiol. 2020 Oct;33(5):685-691. DOI (Digital Object Identifier) : 10.1097/ACO.0000000000000911 PMID : 32826625 En línea : https://journals.lww.com/co-anesthesiology/Abstract/2020/10000/Diaphragm_sparing [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5129 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001388 AC-2020-065 Archivo digital Producción Científica Artículos científicos Disponible Metastatic papillary carcinoma to the neck, thinking beyond the thyroid gland / Carlos Simón Duque Fisher
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Título : Metastatic papillary carcinoma to the neck, thinking beyond the thyroid gland Otros títulos : Carcinoma papilar metastásico a cuello, pensar más allá de la glándula tiroides Tipo de documento : documento electrónico Autores : Carlos Simón Duque Fisher, Fecha de publicación : 2020 Títulos uniformes : Revista Mexicana de Patología Clínica Idioma : Inglés (eng) Palabras clave : Lung cancer thyroid cancer neck dissection immunohistochemistry Resumen : Introduction: A description of a male patient with prior treatment for a right lung adenocarcinoma and a close follow-up for a right thyroid lobe 7 mm papillary cancer, who developed massive right neck metastasis. Objective: To describe the diagnostic dilemma to confirm or rule out the origin of the multiple neck metastasis to avoid unnecessary treatments. Methods: The biopsies from the lung, thyroid and neck tissues were reviewed and examined with immunohistochemistry. Results: The neck metastasis originated from an adenocarcinoma of the lung with papillary features. Conclusions: Unnecessary radioactive iodine treatments were avoided, thanks to the tumor markers. Mención de responsabilidad : Duque CS, Moreno A, Serna OC, Agudelo M DOI (Digital Object Identifier) : 10.35366/96680 En línea : https://www.medigraphic.com/cgi-bin/new/resumenI.cgi?IDARTICULO=96680 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5747 Metastatic papillary carcinoma to the neck, thinking beyond the thyroid gland = Carcinoma papilar metastásico a cuello, pensar más allá de la glándula tiroides [documento electrónico] / Carlos Simón Duque Fisher, . - 2020.
Obra : Revista Mexicana de Patología Clínica
Idioma : Inglés (eng)
Palabras clave : Lung cancer thyroid cancer neck dissection immunohistochemistry Resumen : Introduction: A description of a male patient with prior treatment for a right lung adenocarcinoma and a close follow-up for a right thyroid lobe 7 mm papillary cancer, who developed massive right neck metastasis. Objective: To describe the diagnostic dilemma to confirm or rule out the origin of the multiple neck metastasis to avoid unnecessary treatments. Methods: The biopsies from the lung, thyroid and neck tissues were reviewed and examined with immunohistochemistry. Results: The neck metastasis originated from an adenocarcinoma of the lung with papillary features. Conclusions: Unnecessary radioactive iodine treatments were avoided, thanks to the tumor markers. Mención de responsabilidad : Duque CS, Moreno A, Serna OC, Agudelo M DOI (Digital Object Identifier) : 10.35366/96680 En línea : https://www.medigraphic.com/cgi-bin/new/resumenI.cgi?IDARTICULO=96680 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5747 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001740 AC-2020-157 Archivo digital Producción Científica Artículos científicos Disponible Estado de salud periodontal de pacientes trasplantados renales y calidad de vida asociada. Estudio exploratorio / Gustavo Adolfo Zuluaga Valencia
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Título : Estado de salud periodontal de pacientes trasplantados renales y calidad de vida asociada. Estudio exploratorio Otros títulos : Periodontal health of renal patients and quality of life associated. Exploratory study Tipo de documento : documento electrónico Autores : Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2020 Títulos uniformes : Odontología Sanmarquina Idioma : Español (spa) Palabras clave : Enfermedades periodontales Inmunosupresores Calidad de vida Trasplante de riñón Enfermedad renal crónica Resumen : Objetivo. Determinar el estado de salud periodontal del paciente trasplantado renal, mediante la revisión de las historias clínicas diligenciadas por odontólogos generales o especialistas así como por la percepción de calidad de vida post-transplante, en relación con la salud bucal. Métodos. Estudio descriptivo transversal con 30 participantes de una unidad de transplante renal de la ciudad de Medellín, Colombia. Se exploraron antecedentes médico-odontológicos personales y familiares, examen bucal y periodontograma completo, por un solo examinador (Kappa= 0,79). Se aplicó la encuesta Oral Health Impact Profile (OHIP-14). Resultados. Edad promedio de 35 años (d.s±20,5), 50% hombres y 70% residentes en Medellín. El 46,7% tuvo falla renal de carácter idiopático. Del 44,3% que presentaron problemas periodontales, el 73% tuvo periodontitis localizada, 31,8% bolsas periodontales de 4 mm. El cuestionario de calidad de vida aplicado mostró dos dimensiones afectadas: dolor físico y malestar psicológico (23,4% y 20% respectivamente). Conclusiones. Los pacientes trasplantados renales tuvieron compromiso periodontal. La severidad medida por la pérdida de inserción, mostró un resultado poco satisfactorio, considerando que los pacientes deben estar libres de factores irritativos e inflamatorios en la boca. El OHIP-14 es un instrumento amigable y sencillo para valorar la calidad de vida asociada a salud bucal. Mención de responsabilidad : Steven Betancur-Quintero, Sebastián Buitrago-Vásquez, Jorge Armando Londoño-Grajales, William Londoño-Cuello, Cecilia María Martínez-Delgado, Gustavo Adolfo Zuluaga-Valencia Referencia : Odontol. Sanmarquina 2020; 23(1): 27-33. DOI (Digital Object Identifier) : 10.15381/os.v23i1.17504 Derechos de uso : CC BY-NC-SA En línea : https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/17504 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5088 Estado de salud periodontal de pacientes trasplantados renales y calidad de vida asociada. Estudio exploratorio = Periodontal health of renal patients and quality of life associated. Exploratory study [documento electrónico] / Gustavo Adolfo Zuluaga Valencia, . - 2020.
Obra : Odontología Sanmarquina
Idioma : Español (spa)
Palabras clave : Enfermedades periodontales Inmunosupresores Calidad de vida Trasplante de riñón Enfermedad renal crónica Resumen : Objetivo. Determinar el estado de salud periodontal del paciente trasplantado renal, mediante la revisión de las historias clínicas diligenciadas por odontólogos generales o especialistas así como por la percepción de calidad de vida post-transplante, en relación con la salud bucal. Métodos. Estudio descriptivo transversal con 30 participantes de una unidad de transplante renal de la ciudad de Medellín, Colombia. Se exploraron antecedentes médico-odontológicos personales y familiares, examen bucal y periodontograma completo, por un solo examinador (Kappa= 0,79). Se aplicó la encuesta Oral Health Impact Profile (OHIP-14). Resultados. Edad promedio de 35 años (d.s±20,5), 50% hombres y 70% residentes en Medellín. El 46,7% tuvo falla renal de carácter idiopático. Del 44,3% que presentaron problemas periodontales, el 73% tuvo periodontitis localizada, 31,8% bolsas periodontales de 4 mm. El cuestionario de calidad de vida aplicado mostró dos dimensiones afectadas: dolor físico y malestar psicológico (23,4% y 20% respectivamente). Conclusiones. Los pacientes trasplantados renales tuvieron compromiso periodontal. La severidad medida por la pérdida de inserción, mostró un resultado poco satisfactorio, considerando que los pacientes deben estar libres de factores irritativos e inflamatorios en la boca. El OHIP-14 es un instrumento amigable y sencillo para valorar la calidad de vida asociada a salud bucal. Mención de responsabilidad : Steven Betancur-Quintero, Sebastián Buitrago-Vásquez, Jorge Armando Londoño-Grajales, William Londoño-Cuello, Cecilia María Martínez-Delgado, Gustavo Adolfo Zuluaga-Valencia Referencia : Odontol. Sanmarquina 2020; 23(1): 27-33. DOI (Digital Object Identifier) : 10.15381/os.v23i1.17504 Derechos de uso : CC BY-NC-SA En línea : https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/17504 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5088 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001318 AC-2020-022 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-022.pdfAdobe Acrobat PDFReal-world analysis of treatment patterns and clinical outcomes in patients with newly diagnosed chronic lymphocytic leukemia from seven Latin American countries / Kenny Mauricio Gálvez Cárdenas
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Título : Real-world analysis of treatment patterns and clinical outcomes in patients with newly diagnosed chronic lymphocytic leukemia from seven Latin American countries Tipo de documento : documento electrónico Autores : Kenny Mauricio Gálvez Cárdenas, Fecha de publicación : 2020 Títulos uniformes : Hematology Idioma : Inglés (eng) Palabras clave : Latin America chronic lymphocytic leukemia treatment pattern real-world evidence fludarabine progression-free survival chlorambucil overall survival Resumen : Objective: To describe chronic lymphocytic leukemia (CLL) treatment patterns and patient outcomes in Latin America. Methods: This chart review study (NCT02559583; 2008–2015)evaluated time to progression (TTP) and overall survival (OS) outcomes among patients with CLL who initiate done (n = 261) to two (n = 96) lines of therapy (LOT) since diagnosis. Differences in TTP and OS were assessed by Kaplan-Meier analysis, with a log-rank test for statistical significance. Association between therapeutic regimen and risk for disease progression or death was estimated using Cox proportional hazard regression. Results: The most commonly prescribed therapies in both LOTs were chlorambucil-, followed by fludarabine- and cyclophosphamide (C)/CHOP-based therapies. Chlorambucil- and C/CHOP-based therapies were largely prescribed to elderly patients (≥65 years) while fludarabine-based therapy was predominantly used by younger patients (≤65 years). In LOT1, relative to chlorambucil-administered patients, those prescribed fludarabine-based therapies had lower risk of disease progression (hazard ratio [HR] and 95% confidence interval [CI] 0.32 [0.19–0.54]), whereas C/CHOP-prescribed patients had higher risk (HR 95%CI 1.88 [1.17–3.04]). Similar results were observed in LOT2. There was no difference in OS between treatments in both LOTs. Discussion: Novel therapies such as kinase inhibitors were rarely prescribed in LOT1 or LOT2in Latin America. The greater TTP observed forfludarabine-based therapies could be attributed to the fact that fludarabine-based therapies are predominantly administered to young and healthy patients. Conclusion: Chlorambucil-based therapy, which has limited benefits, is frequently prescribed in Latin America. Prescribing novel agents for fludarabine-based therapy-ineligible patients with CLL is the need of the hour. Mención de responsabilidad : Carlos Chiattone, David Gomez-Almaguer, Carolina Pavlovsky, Elena J. Tuna-Aguilar, Ana L. Basquiera, Luis Palmer, Danielle Leao Cordeiro de Farias, Sergio Schusterschitz da Silva Araujo, Kenny Mauricio Galvez-Cardenas, Alvaro Gomez Diaz, Jennifer H. Lin, Yen-wen Chen, Gerardo Machnicki, Michelle Mahler, Lori Parisi & Paula Barreyro Referencia : Hematology. 2020 Dec;25(1):366-371. DOI (Digital Object Identifier) : 10.1080/16078454.2020.1833504 PMID : 33095117 Derechos de uso : CC BY-NC En línea : https://www.tandfonline.com/doi/full/10.1080/16078454.2020.1833504 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5152 Real-world analysis of treatment patterns and clinical outcomes in patients with newly diagnosed chronic lymphocytic leukemia from seven Latin American countries [documento electrónico] / Kenny Mauricio Gálvez Cárdenas, . - 2020.
Obra : Hematology
Idioma : Inglés (eng)
Palabras clave : Latin America chronic lymphocytic leukemia treatment pattern real-world evidence fludarabine progression-free survival chlorambucil overall survival Resumen : Objective: To describe chronic lymphocytic leukemia (CLL) treatment patterns and patient outcomes in Latin America. Methods: This chart review study (NCT02559583; 2008–2015)evaluated time to progression (TTP) and overall survival (OS) outcomes among patients with CLL who initiate done (n = 261) to two (n = 96) lines of therapy (LOT) since diagnosis. Differences in TTP and OS were assessed by Kaplan-Meier analysis, with a log-rank test for statistical significance. Association between therapeutic regimen and risk for disease progression or death was estimated using Cox proportional hazard regression. Results: The most commonly prescribed therapies in both LOTs were chlorambucil-, followed by fludarabine- and cyclophosphamide (C)/CHOP-based therapies. Chlorambucil- and C/CHOP-based therapies were largely prescribed to elderly patients (≥65 years) while fludarabine-based therapy was predominantly used by younger patients (≤65 years). In LOT1, relative to chlorambucil-administered patients, those prescribed fludarabine-based therapies had lower risk of disease progression (hazard ratio [HR] and 95% confidence interval [CI] 0.32 [0.19–0.54]), whereas C/CHOP-prescribed patients had higher risk (HR 95%CI 1.88 [1.17–3.04]). Similar results were observed in LOT2. There was no difference in OS between treatments in both LOTs. Discussion: Novel therapies such as kinase inhibitors were rarely prescribed in LOT1 or LOT2in Latin America. The greater TTP observed forfludarabine-based therapies could be attributed to the fact that fludarabine-based therapies are predominantly administered to young and healthy patients. Conclusion: Chlorambucil-based therapy, which has limited benefits, is frequently prescribed in Latin America. Prescribing novel agents for fludarabine-based therapy-ineligible patients with CLL is the need of the hour. Mención de responsabilidad : Carlos Chiattone, David Gomez-Almaguer, Carolina Pavlovsky, Elena J. Tuna-Aguilar, Ana L. Basquiera, Luis Palmer, Danielle Leao Cordeiro de Farias, Sergio Schusterschitz da Silva Araujo, Kenny Mauricio Galvez-Cardenas, Alvaro Gomez Diaz, Jennifer H. Lin, Yen-wen Chen, Gerardo Machnicki, Michelle Mahler, Lori Parisi & Paula Barreyro Referencia : Hematology. 2020 Dec;25(1):366-371. DOI (Digital Object Identifier) : 10.1080/16078454.2020.1833504 PMID : 33095117 Derechos de uso : CC BY-NC En línea : https://www.tandfonline.com/doi/full/10.1080/16078454.2020.1833504 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5152 Reserva
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2020-090.pdfAdobe Acrobat PDFNephrotic syndrome associated with primary atypical hemolytic uremic syndrome / John Fredy Nieto Ríos
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Título : Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, Fecha de publicación : 2020 Títulos uniformes : Brazilian Journal of Nephrology Idioma : Inglés (eng) Palabras clave : Atypical Hemolytic Uremic Syndrome Nephrotic Syndrome Acute Renal Injury Hypertension Complement System Proteins Resumen : Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment. Mención de responsabilidad : Diana Carolina Bello-Marquez, John Fredy Nieto-Rios, Lina Maria Serna-Higuita, Alfonso Jose Gonzalez-Vergara Referencia : J Bras Nefrol. Jul-Sep 2021;43(3):440-444. DOI (Digital Object Identifier) : 10.1590/2175-8239-jbn-2020-0050 PMID : 32779691 Derechos de uso : CC BY En línea : https://bjnephrology.org/en/article/nephrotic-syndrome-associated-with-primary-a [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5738 Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome [documento electrónico] / John Fredy Nieto Ríos, . - 2020.
Obra : Brazilian Journal of Nephrology
Idioma : Inglés (eng)
Palabras clave : Atypical Hemolytic Uremic Syndrome Nephrotic Syndrome Acute Renal Injury Hypertension Complement System Proteins Resumen : Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment. Mención de responsabilidad : Diana Carolina Bello-Marquez, John Fredy Nieto-Rios, Lina Maria Serna-Higuita, Alfonso Jose Gonzalez-Vergara Referencia : J Bras Nefrol. Jul-Sep 2021;43(3):440-444. DOI (Digital Object Identifier) : 10.1590/2175-8239-jbn-2020-0050 PMID : 32779691 Derechos de uso : CC BY En línea : https://bjnephrology.org/en/article/nephrotic-syndrome-associated-with-primary-a [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5738 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001677 AC-2020-148 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-148Adobe Acrobat PDFClinical behavior and outcome of papillary T1 thyroid cancers: South Korea vs. Turkey vs. Colombia. A cohort study analyzing oncological outcomes / Juan Pablo Dueñas Muñoz
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Título : Clinical behavior and outcome of papillary T1 thyroid cancers: South Korea vs. Turkey vs. Colombia. A cohort study analyzing oncological outcomes Tipo de documento : documento electrónico Autores : Juan Pablo Dueñas Muñoz, Fecha de publicación : 2020 Títulos uniformes : Asian Journal of Surgery Idioma : Inglés (eng) Palabras clave : Colombia Geographical difference South Korea Thyroid cancer Turkey Resumen : Background/purpose: There has not been an international multicentric study to examine the relationship between thyroid cancer clinical outcomes and geographic location for South Korea, Colombia, and Turkey, whereas thyroid cancer is amongst the highest three cancer types seen in South Korea and Turkey. The aim of the study was to assess regional differences of T1 papillary thyroid cancer outcomes in Korea, Turkey and Colombia. Methods: This is an observational non-randomized study. A total of 2720 patients who have been operated for T1 papillary thyroid cancer between 2011 and 2014 and are on routine follow-up have been recruited. The mean follow-up was 46.4 ± 10.7 months. Data were collected in a commonly used database and analyses were conducted. Results: Patients participated in South Korea (88.2%), Turkey (9.1%) and Colombia (2.6%). Eighty percent were female. Female dominance tended to be higher in Colombia (p = 0.01). Mean age at diagnosis was 45.2 years. There was no mortality. Recurrence tended to be higher in Colombia (p Mención de responsabilidad : Murat Ozdemir, Yong-Sang Lee, Ozer Makay, Juan Pablo Dueñas, Bulent Yazici, Aysegul Akgun, Gokhan Icoz, Mahir Akyildiz, Soo Young Kim, Seok-Mo Kim, Hojin Chang, Hang-Seok Chang, Cheong Soo Park Referencia : Asian J Surg. 2020 Aug;43(8):795-798. DOI (Digital Object Identifier) : 10.1016/j.asjsur.2019.10.005 PMID : 31791715 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S1015-9584(19)30823-1 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5079 Clinical behavior and outcome of papillary T1 thyroid cancers: South Korea vs. Turkey vs. Colombia. A cohort study analyzing oncological outcomes [documento electrónico] / Juan Pablo Dueñas Muñoz, . - 2020.
Obra : Asian Journal of Surgery
Idioma : Inglés (eng)
Palabras clave : Colombia Geographical difference South Korea Thyroid cancer Turkey Resumen : Background/purpose: There has not been an international multicentric study to examine the relationship between thyroid cancer clinical outcomes and geographic location for South Korea, Colombia, and Turkey, whereas thyroid cancer is amongst the highest three cancer types seen in South Korea and Turkey. The aim of the study was to assess regional differences of T1 papillary thyroid cancer outcomes in Korea, Turkey and Colombia. Methods: This is an observational non-randomized study. A total of 2720 patients who have been operated for T1 papillary thyroid cancer between 2011 and 2014 and are on routine follow-up have been recruited. The mean follow-up was 46.4 ± 10.7 months. Data were collected in a commonly used database and analyses were conducted. Results: Patients participated in South Korea (88.2%), Turkey (9.1%) and Colombia (2.6%). Eighty percent were female. Female dominance tended to be higher in Colombia (p = 0.01). Mean age at diagnosis was 45.2 years. There was no mortality. Recurrence tended to be higher in Colombia (p Mención de responsabilidad : Murat Ozdemir, Yong-Sang Lee, Ozer Makay, Juan Pablo Dueñas, Bulent Yazici, Aysegul Akgun, Gokhan Icoz, Mahir Akyildiz, Soo Young Kim, Seok-Mo Kim, Hojin Chang, Hang-Seok Chang, Cheong Soo Park Referencia : Asian J Surg. 2020 Aug;43(8):795-798. DOI (Digital Object Identifier) : 10.1016/j.asjsur.2019.10.005 PMID : 31791715 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S1015-9584(19)30823-1 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5079 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001309 AC-2020-013 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-013.pdfAdobe Acrobat PDFSIRS o no SIRS: ¿es esa la infección? Una revisión crítica de los criterios de definición de sepsis / Byron Enrique Piñeres Olave
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Título : SIRS o no SIRS: ¿es esa la infección? Una revisión crítica de los criterios de definición de sepsis Otros títulos : SIRS or not SIRS: Is that the infection? A critical review of the sepsis definition criteria Tipo de documento : documento electrónico Autores : Byron Enrique Piñeres Olave, Fecha de publicación : 2020 Títulos uniformes : Boletín Médico del Hospital Infantil de México Idioma : Español (spa) Palabras clave : Sepsis SIRS qSOFA Choque séptico Definición Pediatría Resumen : El enfoque moderno de la sepsis se ha centrado en la creación de consensos globales que utilizan distintos criterios para pesquisarla en forma precoz, con el fin de disminuir la morbimortalidad asociada a ella. Hasta la aparición del tercer y último consenso de adultos (Sepsis-3), el síndrome de respuesta inflamatoria sistémica (SIRS) fue el pilar diagnóstico utilizado por defecto en todas las edades. En Sepsis-3 se decidió retirar el SIRS, lo que generó un debate internacional sobre la oportunidad de dicho cambio. Esta revisión narrativa desarrolla la historia de las distintas definiciones de sepsis centradas en SIRS, las fortalezas, las debilidades y la pertinencia de los distintos elementos que ocasionaron el debate. Dada la ausencia de actualizaciones pediátricas en Sepsis-3, se hace especial énfasis en las implicaciones para las futuras definiciones de sepsis en esta etapa de la vida. Mención de responsabilidad : Juan C. Jaramillo-Bustamante, Byron E. Piñeres-Olave y Sebastián González-Dambrauskas Referencia : Bol Med Hosp Infant Mex. 2020;77(6):293-302. DOI (Digital Object Identifier) : 10.24875/BMHIM.20000202 PMID : 33186343 Derechos de uso : CC BY-NC-ND En línea : http://www.bmhim.com/frame_esp.php?id=142 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5111 SIRS o no SIRS: ¿es esa la infección? Una revisión crítica de los criterios de definición de sepsis = SIRS or not SIRS: Is that the infection? A critical review of the sepsis definition criteria [documento electrónico] / Byron Enrique Piñeres Olave, . - 2020.
Obra : Boletín Médico del Hospital Infantil de México
Idioma : Español (spa)
Palabras clave : Sepsis SIRS qSOFA Choque séptico Definición Pediatría Resumen : El enfoque moderno de la sepsis se ha centrado en la creación de consensos globales que utilizan distintos criterios para pesquisarla en forma precoz, con el fin de disminuir la morbimortalidad asociada a ella. Hasta la aparición del tercer y último consenso de adultos (Sepsis-3), el síndrome de respuesta inflamatoria sistémica (SIRS) fue el pilar diagnóstico utilizado por defecto en todas las edades. En Sepsis-3 se decidió retirar el SIRS, lo que generó un debate internacional sobre la oportunidad de dicho cambio. Esta revisión narrativa desarrolla la historia de las distintas definiciones de sepsis centradas en SIRS, las fortalezas, las debilidades y la pertinencia de los distintos elementos que ocasionaron el debate. Dada la ausencia de actualizaciones pediátricas en Sepsis-3, se hace especial énfasis en las implicaciones para las futuras definiciones de sepsis en esta etapa de la vida. Mención de responsabilidad : Juan C. Jaramillo-Bustamante, Byron E. Piñeres-Olave y Sebastián González-Dambrauskas Referencia : Bol Med Hosp Infant Mex. 2020;77(6):293-302. DOI (Digital Object Identifier) : 10.24875/BMHIM.20000202 PMID : 33186343 Derechos de uso : CC BY-NC-ND En línea : http://www.bmhim.com/frame_esp.php?id=142 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5111 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001342 AC-2020-046 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-046.pdfAdobe Acrobat PDFDiabetes mellitus en COVID-19: ¿factor de riesgo o factor pronóstico? / Carlos Esteban Builes Montaño
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Título : Diabetes mellitus en COVID-19: ¿factor de riesgo o factor pronóstico? Otros títulos : Diabetes mellitus and COVID-19: Risk or prognostic factor? Tipo de documento : documento electrónico Autores : Carlos Esteban Builes Montaño, Fecha de publicación : 2020 Títulos uniformes : Revista Colombiana de Endocrinología Diabetes y Metabolismo Idioma : Español (spa) Palabras clave : diabetes mellitus COVID-19 factores de riesgo pronóstico cuidados críticos insuficiencia respiratoria muerte Resumen : Antecedentes y propósito: la diabetes mellitus es una de las enfermedades crónicas no transmisibles de mayor prevalencia en el mundo. La frecuencia con la que se reporta en los pacientes con COVID-19 es alta. Sin embargo, no es claro si las personas que padecen diabetes mellitus tienen un mayor riesgo de infección o, si una vez infectados, tienen un peor pronóstico. Nuestro propósito fue revisar y analizar la información disponible de COVID-19 y diabetes mellitus e intentar entender mejor el riesgo al que están expuestas las personas con diabetes mellitus durante la pandemia por COVID-19. Métodos: se revisaron las bases de datos PubMed, Cochrane Database of Systematic Reviews, Google Scholar, Scopus y Epistemonikos en búsqueda de registros nacionales epidemiológicos y revisiones sistemáticas, utilizando los términos “Diabetes Mellitus” “COVID-19”, “Factores de riesgo”, “Pronostico”, “Cuidado Critico”, “Insuficiencia Respiratoria” y “Muerte”. Se seleccionaron para análisis las revisiones sistemáticas de las comorbilidades en pacientes con COVID-19, las que analizaban el curso de la enfermedad y los factores pronósticos en pacientes con COVID-19 y aquellas que incluían modelos de pronóstico. Resultados: la información disponible sugiere que la diabetes mellitus es una comorbilidad frecuente en las personas con COVID-19, pero es difícil diferenciar si esto es debido a la alta prevalencia de la diabetes mellitus o a un riesgo más alto de infección. Las personas con diabetes mellitus parecieran tener un riesgo más alto de presentar una forma grave o de morir a causa de la COVID-19. Mención de responsabilidad : Builes-Montaño CE, Ramírez-Rincón A Derechos de uso : CC BY-NC-ND En línea : http://revistaendocrino.org/index.php/rcedm/article/view/585 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5143 Diabetes mellitus en COVID-19: ¿factor de riesgo o factor pronóstico? = Diabetes mellitus and COVID-19: Risk or prognostic factor? [documento electrónico] / Carlos Esteban Builes Montaño, . - 2020.
Obra : Revista Colombiana de Endocrinología Diabetes y Metabolismo
Idioma : Español (spa)
Palabras clave : diabetes mellitus COVID-19 factores de riesgo pronóstico cuidados críticos insuficiencia respiratoria muerte Resumen : Antecedentes y propósito: la diabetes mellitus es una de las enfermedades crónicas no transmisibles de mayor prevalencia en el mundo. La frecuencia con la que se reporta en los pacientes con COVID-19 es alta. Sin embargo, no es claro si las personas que padecen diabetes mellitus tienen un mayor riesgo de infección o, si una vez infectados, tienen un peor pronóstico. Nuestro propósito fue revisar y analizar la información disponible de COVID-19 y diabetes mellitus e intentar entender mejor el riesgo al que están expuestas las personas con diabetes mellitus durante la pandemia por COVID-19. Métodos: se revisaron las bases de datos PubMed, Cochrane Database of Systematic Reviews, Google Scholar, Scopus y Epistemonikos en búsqueda de registros nacionales epidemiológicos y revisiones sistemáticas, utilizando los términos “Diabetes Mellitus” “COVID-19”, “Factores de riesgo”, “Pronostico”, “Cuidado Critico”, “Insuficiencia Respiratoria” y “Muerte”. Se seleccionaron para análisis las revisiones sistemáticas de las comorbilidades en pacientes con COVID-19, las que analizaban el curso de la enfermedad y los factores pronósticos en pacientes con COVID-19 y aquellas que incluían modelos de pronóstico. Resultados: la información disponible sugiere que la diabetes mellitus es una comorbilidad frecuente en las personas con COVID-19, pero es difícil diferenciar si esto es debido a la alta prevalencia de la diabetes mellitus o a un riesgo más alto de infección. Las personas con diabetes mellitus parecieran tener un riesgo más alto de presentar una forma grave o de morir a causa de la COVID-19. Mención de responsabilidad : Builes-Montaño CE, Ramírez-Rincón A Derechos de uso : CC BY-NC-ND En línea : http://revistaendocrino.org/index.php/rcedm/article/view/585 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5143 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001568 AC-2020-081 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-081.pdfAdobe Acrobat PDFSíndrome de Osler-Weber-Rendu: presentación de un caso clínico y revisión de la literatura / Juan Carlos Restrepo Gutiérrez
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Título : Síndrome de Osler-Weber-Rendu: presentación de un caso clínico y revisión de la literatura Otros títulos : Osler-Weber-Rendu syndrome: a case report and literature review Tipo de documento : documento electrónico Autores : Juan Carlos Restrepo Gutiérrez, Fecha de publicación : 2020 Títulos uniformes : Hepatología Idioma : Español (spa) Palabras clave : enfermedad de Osler-Rendu telangiectasia hemorrágica hereditaria epistaxis malformaciones arteriovenosas Resumen : El síndrome de Osler-Weber-Rendu, también conocido como telangiectasia hemorrágica hereditaria, es una enfermedad de herencia autosómica dominante de baja prevalencia, que se caracteriza por unas paredes delgadas de los vasos sanguíneos que conducen a malformaciones arteriovenosas, principalmente en cerebro, pulmón e hígado, pero que pueden potencialmente afectar cualquier otro órgano. La principal manifestación clínica son las epistaxis recurrentes; sin embargo, también pueden aparecer otras manifestaciones como hemoptisis o sangrado gastrointestinal, y telangiectasias mucocutáneas, entre otras. Su expresión clínica varía de un paciente a otro y el diagnóstico usualmente se basa en los criterios de Curazao. Se describe el caso de una paciente con historia de 12 años de epistaxis recurrente, a quien se le diagnosticó síndrome de Osler-Weber-Rendu hace dos años. Fue referida al servicio de Hepatología por presentar compromiso hepático, además de malformaciones arteriovenosas cerebrales y pulmonares. El manejo óptimo de la telangiectasia hemorrágica en esta paciente por parte de los diferentes especialistas, apoyado en los estudios de imagenología, ha permitido que la paciente tenga una buena calidad de vida hasta el momento. Se presenta el caso de esta paciente de 46 años y se realiza una revisión corta de la literatura. Mención de responsabilidad : Raúl Felipe Henao-Estrada, Daniela Jaramillo-Bedoya, Susana Castro-Sánchez, Jennifer Vizcaíno-Carruyo, Juan Carlos Restrepo-Gutiérrez DOI (Digital Object Identifier) : 10.52784/27112330.125 Derechos de uso : CC BY-NC-ND En línea : https://revistahepatologia.com/index.php/hepa/article/view/25 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5175 Síndrome de Osler-Weber-Rendu: presentación de un caso clínico y revisión de la literatura = Osler-Weber-Rendu syndrome: a case report and literature review [documento electrónico] / Juan Carlos Restrepo Gutiérrez, . - 2020.
Obra : Hepatología
Idioma : Español (spa)
Palabras clave : enfermedad de Osler-Rendu telangiectasia hemorrágica hereditaria epistaxis malformaciones arteriovenosas Resumen : El síndrome de Osler-Weber-Rendu, también conocido como telangiectasia hemorrágica hereditaria, es una enfermedad de herencia autosómica dominante de baja prevalencia, que se caracteriza por unas paredes delgadas de los vasos sanguíneos que conducen a malformaciones arteriovenosas, principalmente en cerebro, pulmón e hígado, pero que pueden potencialmente afectar cualquier otro órgano. La principal manifestación clínica son las epistaxis recurrentes; sin embargo, también pueden aparecer otras manifestaciones como hemoptisis o sangrado gastrointestinal, y telangiectasias mucocutáneas, entre otras. Su expresión clínica varía de un paciente a otro y el diagnóstico usualmente se basa en los criterios de Curazao. Se describe el caso de una paciente con historia de 12 años de epistaxis recurrente, a quien se le diagnosticó síndrome de Osler-Weber-Rendu hace dos años. Fue referida al servicio de Hepatología por presentar compromiso hepático, además de malformaciones arteriovenosas cerebrales y pulmonares. El manejo óptimo de la telangiectasia hemorrágica en esta paciente por parte de los diferentes especialistas, apoyado en los estudios de imagenología, ha permitido que la paciente tenga una buena calidad de vida hasta el momento. Se presenta el caso de esta paciente de 46 años y se realiza una revisión corta de la literatura. Mención de responsabilidad : Raúl Felipe Henao-Estrada, Daniela Jaramillo-Bedoya, Susana Castro-Sánchez, Jennifer Vizcaíno-Carruyo, Juan Carlos Restrepo-Gutiérrez DOI (Digital Object Identifier) : 10.52784/27112330.125 Derechos de uso : CC BY-NC-ND En línea : https://revistahepatologia.com/index.php/hepa/article/view/25 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5175 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001660 AC-2020-115 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
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2020-115.pdfAdobe Acrobat PDFDistal insertional anatomy of the triceps brachii muscle: MRI assessment in cadaveric specimens Employing Histologic Correlation and Play-doh ® Models of the Anatomic Findings / Francisco Alejandro Ramírez Ruiz
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Título : Distal insertional anatomy of the triceps brachii muscle: MRI assessment in cadaveric specimens Employing Histologic Correlation and Play-doh ® Models of the Anatomic Findings Tipo de documento : documento electrónico Autores : Francisco Alejandro Ramírez Ruiz, Fecha de publicación : 2020 Títulos uniformes : Skeletal Radiology Idioma : Inglés (eng) Palabras clave : Cadavers Insertion anatomy Magnetic resonance imaging Triceps brachii tendon Resumen : Objectives: Assess the insertional anatomy of the distal aspect of the triceps brachii muscle using magnetic resonance imaging (MRI) in cadavers with histologic correlation and Play-doh® models of the anatomic findings. Materials: Elbows were obtained from twelve cadaveric arm specimens by transverse sectioning through the proximal portion of the humerus and the midportion of the radius and ulna. MRI was performed in all elbows. Two of the elbow specimens were then dissected while ten were studied histologically. Subsequently, Play-doh® models of the anatomic findings of the distal attachment sites of the triceps brachii muscle were prepared. Results: MRI showed a dual partitioned appearance of the distal attachment sites into the olecranon in all specimens. In the deeper tissue planes, the medial head muscle insertion was clearly identified while superficially, the terminal portion of the long and lateral heads appeared as a conjoined tendon. Histologic analysis, however, showed continuous tissue rather than separate structures attaching to the olecranon. Conclusion: Although MRI appeared to reveal separate and distinct attachments of the triceps brachii muscle into the olecranon, histologic analysis delineated complex but continuous tissue related to the attachments of the three heads of this muscle. The Play-doh® models were helpful for the comprehension of this complex anatomy and might serve as a valuable educational tool when applied to the analysis of other musculoskeletal regions. Mención de responsabilidad : José Renato Negrão, Roberto Mogami, Francisco Alejandro Ramirez Ruiz, Felipe Victora Wagner, Parviz Haghighi, Samuel R Ward, Donald L Resnick Referencia : Skeletal Radiol. 2020 Jul;49(7):1057-1067. DOI (Digital Object Identifier) : 10.1007/s00256-020-03382-3 PMID : 31993688 En línea : https://link.springer.com/article/10.1007%2Fs00256-020-03382-3 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5069 Distal insertional anatomy of the triceps brachii muscle: MRI assessment in cadaveric specimens Employing Histologic Correlation and Play-doh ® Models of the Anatomic Findings [documento electrónico] / Francisco Alejandro Ramírez Ruiz, . - 2020.
Obra : Skeletal Radiology
Idioma : Inglés (eng)
Palabras clave : Cadavers Insertion anatomy Magnetic resonance imaging Triceps brachii tendon Resumen : Objectives: Assess the insertional anatomy of the distal aspect of the triceps brachii muscle using magnetic resonance imaging (MRI) in cadavers with histologic correlation and Play-doh® models of the anatomic findings. Materials: Elbows were obtained from twelve cadaveric arm specimens by transverse sectioning through the proximal portion of the humerus and the midportion of the radius and ulna. MRI was performed in all elbows. Two of the elbow specimens were then dissected while ten were studied histologically. Subsequently, Play-doh® models of the anatomic findings of the distal attachment sites of the triceps brachii muscle were prepared. Results: MRI showed a dual partitioned appearance of the distal attachment sites into the olecranon in all specimens. In the deeper tissue planes, the medial head muscle insertion was clearly identified while superficially, the terminal portion of the long and lateral heads appeared as a conjoined tendon. Histologic analysis, however, showed continuous tissue rather than separate structures attaching to the olecranon. Conclusion: Although MRI appeared to reveal separate and distinct attachments of the triceps brachii muscle into the olecranon, histologic analysis delineated complex but continuous tissue related to the attachments of the three heads of this muscle. The Play-doh® models were helpful for the comprehension of this complex anatomy and might serve as a valuable educational tool when applied to the analysis of other musculoskeletal regions. Mención de responsabilidad : José Renato Negrão, Roberto Mogami, Francisco Alejandro Ramirez Ruiz, Felipe Victora Wagner, Parviz Haghighi, Samuel R Ward, Donald L Resnick Referencia : Skeletal Radiol. 2020 Jul;49(7):1057-1067. DOI (Digital Object Identifier) : 10.1007/s00256-020-03382-3 PMID : 31993688 En línea : https://link.springer.com/article/10.1007%2Fs00256-020-03382-3 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5069 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001299 AC-2020-003 Archivo digital Producción Científica Artículos científicos Disponible International and multicenter real‐world study of sorafenib‐treated patients with hepatocellular carcinoma under dialysis / Juan Ignacio Marín Zuluaga
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Título : International and multicenter real‐world study of sorafenib‐treated patients with hepatocellular carcinoma under dialysis Tipo de documento : documento electrónico Autores : Juan Ignacio Marín Zuluaga, Fecha de publicación : 2020 Títulos uniformes : Liver International Idioma : Inglés (eng) Palabras clave : Hepatocellular carcinoma sorafenib dialysis adverse events safety survival Resumen : Background & Aims: Information on safety and efficacy of systemic treatment in patients with hepatocellular carcinoma (HCC) under dialysis are limited due to patient exclusion from clinical trials. Thus, we aimed to evaluate the rate, prevalence, tolerability, and outcome of sorafenib in this population. Methods: We report a multicenter study comprising patients from Latin America and Europe. Patients treated with sorafenib were enrolled; demographics, dose modifications, adverse events (AEs), treatment duration, and outcome of patients undergoing dialysis were recorded. Results: As of March 2018, 6156 HCC patients were treated in 44 centres and 22 patients were concomitantly under dialysis (0.36%). The median age was 65.5 years, 40.9% had hepatitis C, 75% had Child‐Pugh A, and 85% were Barcelona Clinic Liver Cancer‐C. The median time to first dose modification, treatment duration and overall survival rate were 2.4 months (interquartile ranges [IQR], 0.8‐3.8), 10.8 months (IQR, 4.5‐16.9), and 17.5 months (95% CI, 7.2‐24.5), respectively. Seventeen patients required at least 1 dose modification. The main causes of first dose modification were asthenia/worsening of Eastern Cooperative Oncology Group‐Performance Status and diarrhoea. At the time of death or last follow‐up, four patients were still on treatment and 18 had discontinued sorafenib: 14 were due to tumour progression, 2 were sorafenib‐related, and 2 were non‐sorafenib‐related AE. Conclusions: The outcomes observed in this cohort seem comparable to those in the non‐dialysis population. Thus, to the best of our knowledge, this is the largest and most informative dataset regarding systemic treatment outcomes in HCC patients undergoing dialysis. Mención de responsabilidad : Álvaro Díaz-González, Marco Sanduzzi-Zamparelli, Leonardo G da Fonseca, Giovan G Di Costanzo, Rogerio Alves, Massimo Iavarone, Cassia Leal, Rodolfo Sacco, Ana M Matilla, Manuel Hernández-Guerra, Gabriel Aballay Soteras, Marcus-Alexander Wörns, Matthias Pinter, María Varela, Morten Ladekarl, Aline L Chagas, Beatriz Mínguez, Juan I Arenas, Alessandro Granito, Yolanda Sánchez-Torrijos, Ángela Rojas, Carlos Rodríguez de Lope, Mario R Alvares-da-Silva, Sonia Pascual, Lorenza Rimassa, José L Lledó, Carlos Huertas, Bruno Sangro, Edoardo G Giannini, Manuel Delgado, Mercedes Vergara, Christie Perelló, Alberto Lue, Margarita Sala, Adolfo Gallego, Susanna Coll, Tania Hernáez, Federico Piñero, Gustavo Pereira, Alex França, Juan Marín, Margarita Anders, Vivianne Mello, Mar Lozano, Jean C Nault, Josemaría Menéndez, Ignacio García Juárez, Jordi Bruix, María Reig Referencia : Liver Int. 2020 Jun;40(6):1467-1476. DOI (Digital Object Identifier) : 10.1111/liv.14436 PMID : 32170821 En línea : https://onlinelibrary.wiley.com/doi/epdf/10.1111/liv.14436 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5102 International and multicenter real‐world study of sorafenib‐treated patients with hepatocellular carcinoma under dialysis [documento electrónico] / Juan Ignacio Marín Zuluaga, . - 2020.
Obra : Liver International
Idioma : Inglés (eng)
Palabras clave : Hepatocellular carcinoma sorafenib dialysis adverse events safety survival Resumen : Background & Aims: Information on safety and efficacy of systemic treatment in patients with hepatocellular carcinoma (HCC) under dialysis are limited due to patient exclusion from clinical trials. Thus, we aimed to evaluate the rate, prevalence, tolerability, and outcome of sorafenib in this population. Methods: We report a multicenter study comprising patients from Latin America and Europe. Patients treated with sorafenib were enrolled; demographics, dose modifications, adverse events (AEs), treatment duration, and outcome of patients undergoing dialysis were recorded. Results: As of March 2018, 6156 HCC patients were treated in 44 centres and 22 patients were concomitantly under dialysis (0.36%). The median age was 65.5 years, 40.9% had hepatitis C, 75% had Child‐Pugh A, and 85% were Barcelona Clinic Liver Cancer‐C. The median time to first dose modification, treatment duration and overall survival rate were 2.4 months (interquartile ranges [IQR], 0.8‐3.8), 10.8 months (IQR, 4.5‐16.9), and 17.5 months (95% CI, 7.2‐24.5), respectively. Seventeen patients required at least 1 dose modification. The main causes of first dose modification were asthenia/worsening of Eastern Cooperative Oncology Group‐Performance Status and diarrhoea. At the time of death or last follow‐up, four patients were still on treatment and 18 had discontinued sorafenib: 14 were due to tumour progression, 2 were sorafenib‐related, and 2 were non‐sorafenib‐related AE. Conclusions: The outcomes observed in this cohort seem comparable to those in the non‐dialysis population. Thus, to the best of our knowledge, this is the largest and most informative dataset regarding systemic treatment outcomes in HCC patients undergoing dialysis. Mención de responsabilidad : Álvaro Díaz-González, Marco Sanduzzi-Zamparelli, Leonardo G da Fonseca, Giovan G Di Costanzo, Rogerio Alves, Massimo Iavarone, Cassia Leal, Rodolfo Sacco, Ana M Matilla, Manuel Hernández-Guerra, Gabriel Aballay Soteras, Marcus-Alexander Wörns, Matthias Pinter, María Varela, Morten Ladekarl, Aline L Chagas, Beatriz Mínguez, Juan I Arenas, Alessandro Granito, Yolanda Sánchez-Torrijos, Ángela Rojas, Carlos Rodríguez de Lope, Mario R Alvares-da-Silva, Sonia Pascual, Lorenza Rimassa, José L Lledó, Carlos Huertas, Bruno Sangro, Edoardo G Giannini, Manuel Delgado, Mercedes Vergara, Christie Perelló, Alberto Lue, Margarita Sala, Adolfo Gallego, Susanna Coll, Tania Hernáez, Federico Piñero, Gustavo Pereira, Alex França, Juan Marín, Margarita Anders, Vivianne Mello, Mar Lozano, Jean C Nault, Josemaría Menéndez, Ignacio García Juárez, Jordi Bruix, María Reig Referencia : Liver Int. 2020 Jun;40(6):1467-1476. DOI (Digital Object Identifier) : 10.1111/liv.14436 PMID : 32170821 En línea : https://onlinelibrary.wiley.com/doi/epdf/10.1111/liv.14436 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5102 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001332 AC-2020-036 Archivo digital Producción Científica Artículos científicos Disponible