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Pediatric Transplantation
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Tipo de obra :
Autre
Naturaleza de la obra :
Oeuvre
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Documentos disponibles con este título uniforme (4)
Clasificado(s) por (Año de edición descendente) Refinar búsquedaCMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia / Laura Fernanda Niño Serna ; Alejandro Díaz Díaz ; Mónica Rosa Trujillo Honeysberg ; Natalia Builes R. ; Arias, Andrés ; Aristizábal, Beatriz H
Título : CMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia Tipo de documento : documento electrónico Autores : Laura Fernanda Niño Serna, Autor ; Alejandro Díaz Díaz, Autor ; Mónica Rosa Trujillo Honeysberg, Autor ; Natalia Builes R., Autor ; Arias, Andrés, Autor ; Aristizábal, Beatriz H, Autor Fecha de publicación : 2025 Títulos uniformes : Pediatric Transplantation Idioma : Inglés (eng) Palabras clave : CMV; cytomegalovirus infection; haploidentical; hematopoietic stem cell transplantation; pediatrics; transplantation Resumen : Introduction: Cytomegalovirus (CMV) infection is a frequent complication among hematopoietic stem cell transplant (HSCT) recipients. Data regarding CMV reactivation in children in underdeveloped countries is scarce. This is especially notable considering the increasing utilization of haploidentical-related HSCT with the post-transplant cyclophosphamide platform. This study aimed to describe the incidence, clinical characteristics, and evolution of children with CMV reactivation after HSCT and the possible impact of unmanipulated stem cells with PTCy for GvHD prophylaxis. Methods: Retrospective cohort study of children undergoing hematopoietic stem cell transplantation from January 2012 to June 2022. Baseline characteristics and the clinical course were described. Duration of treatment, initial viral load, and time to clearance of DNAemia by type of transplant were compared using the Kruskal-Wallis test. Survival analysis was performed with the Kaplan–Meier method and log-rank test. All statistical analysis was performed using SPSS software, version 20.0. Results: One hundred sixty-six children were included. Among them, 87% of recipients and 88% of donors were CMV positive. The cumulative incidence of cytomegalovirus DNAemia was 28% at 100 days post-transplantation. There were no differences between different donor types. Overall survival at 1 year was 60%, and non-relapse mortality was observed in 28%. CMV reactivation did not appear to negatively impact 1-year overall survival (OS). Conclusions: Our study found no differences in CMV reactivation rates, treatment duration, viral clearance times, co-infections, or 1-year overall survival across different HSCT donor types. Studies are needed to establish more precise criteria for monitoring recipients, particularly in regions where unmanipulated stem cells with PTCy for GvHD prophylaxis are increasing. © 2025 Wiley Periodicals LLC. Mención de responsabilidad : Arias, Andres, Builes, Natalia, Niño-Serna, Laura, Diaz, Alejandro, Aristizabal, Beatriz H., Trujillo, Monica. Referencia : Pediatr Transplant . 2025 Feb;29(1):e70033 DOI (Digital Object Identifier) : 10.1111/petr.70033 PMID : 39837777 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39837777/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis CMV Reactivation Following Allogeneic Transplantation in Children From a High-Seroprevalence Population: A Single-Center Experience in Colombia [documento electrónico] / Laura Fernanda Niño Serna, Autor ; Alejandro Díaz Díaz, Autor ; Mónica Rosa Trujillo Honeysberg, Autor ; Natalia Builes R., Autor ; Arias, Andrés, Autor ; Aristizábal, Beatriz H, Autor . - 2025.
Obra : Pediatric Transplantation
Idioma : Inglés (eng)
Palabras clave : CMV; cytomegalovirus infection; haploidentical; hematopoietic stem cell transplantation; pediatrics; transplantation Resumen : Introduction: Cytomegalovirus (CMV) infection is a frequent complication among hematopoietic stem cell transplant (HSCT) recipients. Data regarding CMV reactivation in children in underdeveloped countries is scarce. This is especially notable considering the increasing utilization of haploidentical-related HSCT with the post-transplant cyclophosphamide platform. This study aimed to describe the incidence, clinical characteristics, and evolution of children with CMV reactivation after HSCT and the possible impact of unmanipulated stem cells with PTCy for GvHD prophylaxis. Methods: Retrospective cohort study of children undergoing hematopoietic stem cell transplantation from January 2012 to June 2022. Baseline characteristics and the clinical course were described. Duration of treatment, initial viral load, and time to clearance of DNAemia by type of transplant were compared using the Kruskal-Wallis test. Survival analysis was performed with the Kaplan–Meier method and log-rank test. All statistical analysis was performed using SPSS software, version 20.0. Results: One hundred sixty-six children were included. Among them, 87% of recipients and 88% of donors were CMV positive. The cumulative incidence of cytomegalovirus DNAemia was 28% at 100 days post-transplantation. There were no differences between different donor types. Overall survival at 1 year was 60%, and non-relapse mortality was observed in 28%. CMV reactivation did not appear to negatively impact 1-year overall survival (OS). Conclusions: Our study found no differences in CMV reactivation rates, treatment duration, viral clearance times, co-infections, or 1-year overall survival across different HSCT donor types. Studies are needed to establish more precise criteria for monitoring recipients, particularly in regions where unmanipulated stem cells with PTCy for GvHD prophylaxis are increasing. © 2025 Wiley Periodicals LLC. Mención de responsabilidad : Arias, Andres, Builes, Natalia, Niño-Serna, Laura, Diaz, Alejandro, Aristizabal, Beatriz H., Trujillo, Monica. Referencia : Pediatr Transplant . 2025 Feb;29(1):e70033 DOI (Digital Object Identifier) : 10.1111/petr.70033 PMID : 39837777 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/39837777/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD002325 AC-2025-008 Archivo digital Producción Científica Artículos científicos Disponible
Título : Meta-analysis of hematopoietic stem cell transplantation in major histocompatibility complex class II deficiency Tipo de documento : documento electrónico Autores : Andrés Felipe Escobar González, Fecha de publicación : 2020 Títulos uniformes : Pediatric Transplantation Idioma : Inglés (eng) Palabras clave : hematopoietic stem cell transplant major histocompatibility complex class II deficiency primary immunodeficiency Resumen : Major histocompatibility complex class II deficiency is a rare case of PID. Specific recommendations for hematopoietic stem cell transplant, the only curative treatment option, are still lacking. This meta‐analysis aims to identify the factors associated with better prognosis in these patients. Thirteen articles reporting 63 patients with major histocompatibility complex class II deficiency that underwent hematopoietic stem cell transplant were included. The median age for hematopoietic stem cell transplant was 18 months. The most common source of transplant was bone marrow, with alternative sources as umbilical cord blood emerging during recent years. The highest proportion of engraftment was seen with umbilical cord. Engraftment was higher in patients with matched donors, with better overall survival in patients with reduced‐intensity conditioning. Graft‐vs‐host disease developed in 65% of the patients, with grades I‐II being the most frequently encountered. There was a higher mortality in patients with myeloablative conditioning and no engraftment. There was an inverse correlation between survival and stage of graft‐vs‐host disease. The main cause of mortality was infectious disease, mostly secondary to viral infections. Ideally, matched grafts should be used, and reduced‐intensity conditioning should be considered to reduce early post‐transplant complications. GVHD and viral prophylaxis are fundamental. Mención de responsabilidad : Lina Maria Castano‐Jaramillo, Jose Bareño‐Silva, Santiago Tobon, Andres Felipe Escobar‐Gonzalez Referencia : Pediatr Transplant. 2020 Sep;24(6):e13774. DOI (Digital Object Identifier) : 10.1111/petr.13774 PMID : 32678504 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/petr.13774 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Meta-analysis of hematopoietic stem cell transplantation in major histocompatibility complex class II deficiency [documento electrónico] / Andrés Felipe Escobar González, . - 2020.
Obra : Pediatric Transplantation
Idioma : Inglés (eng)
Palabras clave : hematopoietic stem cell transplant major histocompatibility complex class II deficiency primary immunodeficiency Resumen : Major histocompatibility complex class II deficiency is a rare case of PID. Specific recommendations for hematopoietic stem cell transplant, the only curative treatment option, are still lacking. This meta‐analysis aims to identify the factors associated with better prognosis in these patients. Thirteen articles reporting 63 patients with major histocompatibility complex class II deficiency that underwent hematopoietic stem cell transplant were included. The median age for hematopoietic stem cell transplant was 18 months. The most common source of transplant was bone marrow, with alternative sources as umbilical cord blood emerging during recent years. The highest proportion of engraftment was seen with umbilical cord. Engraftment was higher in patients with matched donors, with better overall survival in patients with reduced‐intensity conditioning. Graft‐vs‐host disease developed in 65% of the patients, with grades I‐II being the most frequently encountered. There was a higher mortality in patients with myeloablative conditioning and no engraftment. There was an inverse correlation between survival and stage of graft‐vs‐host disease. The main cause of mortality was infectious disease, mostly secondary to viral infections. Ideally, matched grafts should be used, and reduced‐intensity conditioning should be considered to reduce early post‐transplant complications. GVHD and viral prophylaxis are fundamental. Mención de responsabilidad : Lina Maria Castano‐Jaramillo, Jose Bareño‐Silva, Santiago Tobon, Andres Felipe Escobar‐Gonzalez Referencia : Pediatr Transplant. 2020 Sep;24(6):e13774. DOI (Digital Object Identifier) : 10.1111/petr.13774 PMID : 32678504 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/petr.13774 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001398 AC-2020-075 Archivo digital Producción Científica Artículos científicos Disponible
Título : Extrahepatic portal vein aneurysm after liver transplantation in a child: case report Tipo de documento : documento electrónico Autores : Lucila Beatriz Molinares Arevalo, ; Sergio Álvarez Vallejo, ; Vanessa García Gómez, ; María Elsy Sepúlveda Hincapie, ; Nora Luz Yepes Palacio, Fecha de publicación : 2013 Títulos uniformes : Pediatric Transplantation Idioma : Inglés (eng) Palabras clave : Liver transplantation portal vein aneurysm Resumen : Portal vein aneurysms are very rare and represent Mención de responsabilidad : Beatriz Molinares, Sergio Alvarez, Vanessa García, Maria Elsy Sepúlveda, Nora Luz Yepes, Sebastián Peláez Referencia : Pediatr Transplantation 2013: 17: E33–E36. DOI (Digital Object Identifier) : 10.1111/j.1399-3046.2012.01782.x PMID : 22943740 En línea : https://onlinelibrary.wiley.com/doi/full/10.1111/j.1399-3046.2012.01782.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Extrahepatic portal vein aneurysm after liver transplantation in a child: case report [documento electrónico] / Lucila Beatriz Molinares Arevalo, ; Sergio Álvarez Vallejo, ; Vanessa García Gómez, ; María Elsy Sepúlveda Hincapie, ; Nora Luz Yepes Palacio, . - 2013.
Obra : Pediatric Transplantation
Idioma : Inglés (eng)
Palabras clave : Liver transplantation portal vein aneurysm Resumen : Portal vein aneurysms are very rare and represent Mención de responsabilidad : Beatriz Molinares, Sergio Alvarez, Vanessa García, Maria Elsy Sepúlveda, Nora Luz Yepes, Sebastián Peláez Referencia : Pediatr Transplantation 2013: 17: E33–E36. DOI (Digital Object Identifier) : 10.1111/j.1399-3046.2012.01782.x PMID : 22943740 En línea : https://onlinelibrary.wiley.com/doi/full/10.1111/j.1399-3046.2012.01782.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000234 AC-2013-002 Archivo digital Producción Científica Artículos científicos Disponible
Título : Hepatic transplantation in a child with giant multicystic tumor: pathological and imaging findings Tipo de documento : documento electrónico Autores : María Elsy Sepúlveda Hincapie, ; Nora Luz Yepes Palacio, ; Sergio Iván Hoyos Duque, Fecha de publicación : 2010 Títulos uniformes : Pediatric Transplantation Idioma : Francés (fre) Palabras clave : Hepatic cystic tumor transplantation pathological imaging Resumen : A 30 month old male white child presented with 13 months of increasing abdominal girth. The MRI and MDCT showed a giant heterogeneous and predominantly cystic mass with thick and nodular septation, measuring approximately 18, 15, 20 cm, which occupied almost the whole liver. A histological diagnosis was not possible, which necessitated transplantation. One year after transplantation the course has been satisfactory without recurrence and with normal hepatic function and negative tumor markers Mención de responsabilidad : Germán A Castrillon, Elsy Sepúlveda, Nora L Yepez, Sergio Hoyos, Germán Osorio Referencia : Pediatr Transplantation 2010 Aug;14(5):e58-61. DOI (Digital Object Identifier) : 10.1111/j.1399-3046.2009.01166.x PMID : 19413715 En línea : https://onlinelibrary.wiley.com/doi/10.1111/j.1399-3046.2009.01166.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Hepatic transplantation in a child with giant multicystic tumor: pathological and imaging findings [documento electrónico] / María Elsy Sepúlveda Hincapie, ; Nora Luz Yepes Palacio, ; Sergio Iván Hoyos Duque, . - 2010.
Obra : Pediatric Transplantation
Idioma : Francés (fre)
Palabras clave : Hepatic cystic tumor transplantation pathological imaging Resumen : A 30 month old male white child presented with 13 months of increasing abdominal girth. The MRI and MDCT showed a giant heterogeneous and predominantly cystic mass with thick and nodular septation, measuring approximately 18, 15, 20 cm, which occupied almost the whole liver. A histological diagnosis was not possible, which necessitated transplantation. One year after transplantation the course has been satisfactory without recurrence and with normal hepatic function and negative tumor markers Mención de responsabilidad : Germán A Castrillon, Elsy Sepúlveda, Nora L Yepez, Sergio Hoyos, Germán Osorio Referencia : Pediatr Transplantation 2010 Aug;14(5):e58-61. DOI (Digital Object Identifier) : 10.1111/j.1399-3046.2009.01166.x PMID : 19413715 En línea : https://onlinelibrary.wiley.com/doi/10.1111/j.1399-3046.2009.01166.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000115 AC-2010-047 Archivo digital Producción Científica Artículos científicos Disponible
