Clinical and immunological characteristics of type 1 diabetes mellitus in a northwestern Colombian population / Verónica Abad Londoño ; Alejandro Daniel Velásquez Urzola  

Público ISBD Título : Clinical and immunological characteristics of type 1 diabetes mellitus in a northwestern Colombian population Tipo de documento : documento electrónico Autores : Verónica Abad Londoño, ; Alejandro Daniel Velásquez Urzola, Fecha de publicación : 2006 Títulos uniformes : Diabetes Research and Clinical Practice Idioma : Inglés (eng) Palabras clave : Type 1 diabetes  GADA  IA-2A  IAA  Colombia Resumen : We underwent a project aimed to define the clinical and immunological characteristics of type 1 diabetes (T1D) in a Colombian population. This was a multicenter and cross-sectional study. Patients were systematically interviewed and their medical records reviewed, using a questionnaire that sought information about demographic, clinical and immunological characteristics. Glutamic acid decarboxylase antibodies (GADA), tyrosine phosphatase antibodies (IA-2A) and insulin antibodies (IAA) were examined by radioimmunoassay. There were 107 patients with T1D. Male:female ratio was 1:1. Half of the patients developed diabetes ketoacidosis at onset. GADA, IA-2A, and IAA were detected in 45%, 40%, and 69% of the cases, respectively. GADA positive patients were older and had a less duration of disease than patients without these autoantibodies ( p  Mención de responsabilidad : G J Tobon, A Arango, V Abad, J García, H Cuervo, A Velásquez, I D Angel, P Vega, A Abad, J-M Anaya Referencia : Diabetes Res Clin Pract. 2006 May;72(2):170-5. DOI (Digital Object Identifier) : 10.1016/j.diabres.2005.10.016 PMID : 16325957 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0168822705004225 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4420 Clinical and immunological characteristics of type 1 diabetes mellitus in a northwestern Colombian population [documento electrónico] / Verónica Abad Londoño, ; Alejandro Daniel Velásquez Urzola,  . - 2006. Obra : Diabetes Research and Clinical Practice Idioma : Inglés (eng) Palabras clave : Type 1 diabetes  GADA  IA-2A  IAA  Colombia Resumen : We underwent a project aimed to define the clinical and immunological characteristics of type 1 diabetes (T1D) in a Colombian population. This was a multicenter and cross-sectional study. Patients were systematically interviewed and their medical records reviewed, using a questionnaire that sought information about demographic, clinical and immunological characteristics. Glutamic acid decarboxylase antibodies (GADA), tyrosine phosphatase antibodies (IA-2A) and insulin antibodies (IAA) were examined by radioimmunoassay. There were 107 patients with T1D. Male:female ratio was 1:1. Half of the patients developed diabetes ketoacidosis at onset. GADA, IA-2A, and IAA were detected in 45%, 40%, and 69% of the cases, respectively. GADA positive patients were older and had a less duration of disease than patients without these autoantibodies ( p  Mención de responsabilidad : G J Tobon, A Arango, V Abad, J García, H Cuervo, A Velásquez, I D Angel, P Vega, A Abad, J-M Anaya Referencia : Diabetes Res Clin Pract. 2006 May;72(2):170-5. DOI (Digital Object Identifier) : 10.1016/j.diabres.2005.10.016 PMID : 16325957 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0168822705004225 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4420

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