Efficacy and safety of endoscopic compared with open surgical repair of cerebrospinal fluid fistulas: a systematic review and meta-analysis / Francisco Javier Londoño Ocampo ; Frusteri, Marco ; Gaviria Zapata, Miguel ; Suárez Sepúlveda, Juan Esteban ; Rivas, Carlos ; Quiceno, Esteban ; Londoño Herrera, Daniel  

Público ISBD Título : Efficacy and safety of endoscopic compared with open surgical repair of cerebrospinal fluid fistulas: a systematic review and meta-analysis Tipo de documento : documento electrónico Autores : Francisco Javier Londoño Ocampo, Autor ; Frusteri, Marco, Autor ; Gaviria Zapata, Miguel, Autor ; Suárez Sepúlveda, Juan Esteban, Autor ; Rivas, Carlos, Autor ; Quiceno, Esteban, Autor ; Londoño Herrera, Daniel, Autor Fecha de publicación : 2025 Títulos uniformes : Neurosurgical Review Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave : Cerebrospinal fluid leak; Endoscopy; Neurosurgery. Resumen : Background and objective: Cerebrospinal fluid leaks or fistulas are a relatively common neurosurgical pathology. Classically, this condition has been managed through an open surgical approach, but endoscopic surgery has emerged as a less invasive alternative with several advantages. Despite this, no meta-analysis has yet directly compared the clinical outcomes of these two management strategies. Methods: A systematic review and meta-analysis were conducted following PRISMA guidelines. The PubMed, Embase, LILACS and Web of Science databases were rigoursly searched. Post-operative repair success rate, risk of recurrence and the risk of presenting any operation-related compilation and the all-cause mortality rate were analyzed. Data were analyzed using a common-effects meta-analysis, and statistical heterogeneity was assessed. The study was registered with PROSPERO (CRD42024606877). Results: Seven studies comprising 360 patients (140 endoscopic, 220 open) were included. Although the point estimate suggested a higher success rate with endoscopic repair, the difference was not statistically significant OR 1.32 (95% CI 0.55-3.16, I2 = 4.4%). The complication rate was significantly lower in the endoscopic group OR 0.26 (95% CI 0.10-0.67, I2 = 38%) and a leave-one-out analysis excluding the study by Gassner et al. found OR 0.10 (95% CI 0.03-0.32, I2 = 0%). Recurrence of CSF fistulas showed a trend favoring endoscopic repair (OR 0.78, 95% CI 0.42-1.43, I2 = 0%). No mortality was reported. Conclusions: Endoscopic CSF fistula repair demonstrates a superior safety profile and is non-inferior in terms of efficacy compared to open surgery. Given the limited number of high-quality studies, further research is needed and larger, well-designed studies are recommended to refine clinical decision-making and optimize patient care. Mención de responsabilidad : Marco Frusteri, Miguel Gaviria Zapata, Juan Esteban Suárez Sepúlveda, Carlos Rivas, Esteban Quiceno, Daniel Londoño Herrera, Francisco Javier Londoño Ocampo Referencia : Neurosurg Rev. 2025 Jul 15;48(1):567. doi: 10.1007/s10143-025-03686-9. DOI (Digital Object Identifier) : 10.1007/s10143-025-03754-0 PMID : 40779209 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40663243/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Efficacy and safety of endoscopic compared with open surgical repair of cerebrospinal fluid fistulas: a systematic review and meta-analysis [documento electrónico] / Francisco Javier Londoño Ocampo, Autor ; Frusteri, Marco, Autor ; Gaviria Zapata, Miguel, Autor ; Suárez Sepúlveda, Juan Esteban, Autor ; Rivas, Carlos, Autor ; Quiceno, Esteban, Autor ; Londoño Herrera, Daniel, Autor . - 2025. Obra : Neurosurgical Review Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave : Cerebrospinal fluid leak; Endoscopy; Neurosurgery. Resumen : Background and objective: Cerebrospinal fluid leaks or fistulas are a relatively common neurosurgical pathology. Classically, this condition has been managed through an open surgical approach, but endoscopic surgery has emerged as a less invasive alternative with several advantages. Despite this, no meta-analysis has yet directly compared the clinical outcomes of these two management strategies. Methods: A systematic review and meta-analysis were conducted following PRISMA guidelines. The PubMed, Embase, LILACS and Web of Science databases were rigoursly searched. Post-operative repair success rate, risk of recurrence and the risk of presenting any operation-related compilation and the all-cause mortality rate were analyzed. Data were analyzed using a common-effects meta-analysis, and statistical heterogeneity was assessed. The study was registered with PROSPERO (CRD42024606877). Results: Seven studies comprising 360 patients (140 endoscopic, 220 open) were included. Although the point estimate suggested a higher success rate with endoscopic repair, the difference was not statistically significant OR 1.32 (95% CI 0.55-3.16, I2 = 4.4%). The complication rate was significantly lower in the endoscopic group OR 0.26 (95% CI 0.10-0.67, I2 = 38%) and a leave-one-out analysis excluding the study by Gassner et al. found OR 0.10 (95% CI 0.03-0.32, I2 = 0%). Recurrence of CSF fistulas showed a trend favoring endoscopic repair (OR 0.78, 95% CI 0.42-1.43, I2 = 0%). No mortality was reported. Conclusions: Endoscopic CSF fistula repair demonstrates a superior safety profile and is non-inferior in terms of efficacy compared to open surgery. Given the limited number of high-quality studies, further research is needed and larger, well-designed studies are recommended to refine clinical decision-making and optimize patient care. Mención de responsabilidad : Marco Frusteri, Miguel Gaviria Zapata, Juan Esteban Suárez Sepúlveda, Carlos Rivas, Esteban Quiceno, Daniel Londoño Herrera, Francisco Javier Londoño Ocampo Referencia : Neurosurg Rev. 2025 Jul 15;48(1):567. doi: 10.1007/s10143-025-03686-9. DOI (Digital Object Identifier) : 10.1007/s10143-025-03754-0 PMID : 40779209 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40663243/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis

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Post-traumatic vasospasm after mild brain trauma, a lesson learned / Francisco Javier Londoño Ocampo    

Público ISBD Título : Post-traumatic vasospasm after mild brain trauma, a lesson learned Tipo de documento : documento electrónico Autores : Francisco Javier Londoño Ocampo, Fecha de publicación : 2022 Títulos uniformes : Advances in Neurology and Neuroscience Idioma : Inglés (eng) Palabras clave : Posttraumatic Vasospasm  Traumatic Brain Injury  Mild Brain Trauma  Balloon Angioplasty  Cerebral Ischemia Resumen : Background: Post-traumatic vasospasm is a frequent secondary injury in patients with traumatic brain injury, occurring in up to 63% of patients and with associated deleterious consequences. Most studies have reported post-traumatic vasospasm in patients with severe or moderate brain trauma; however, there are documented cases of post-traumatic vasospasm in patients with mild traumatic brain injury that support a more aggressive search to prevent deleterious neurological outcomes. Observation(s): The pertinent literature has been reviewed, and an exemplary case has been reported (post-traumatic vasospasm associated with mild brain trauma in an adult patient that subsequently transformed into cerebral ischemia that was managed with endovascular therapy and oral nimodipine without subsequent neurological deterioration). To date, only 4 cases have been described, to our knowledge this is the first literature review so far. Lessons: Given the possibility of post-traumatic vasospasm associated with mild brain trauma, the authors believe that GCS score alone may be an inadequate risk predictor of symptomatic cerebral vasospasm and a more aggressive search should be performed in patients with mild trauma who present with neurological deterioration without apparent cause. Mención de responsabilidad : Felipe Gutierrez Pineda, Mauro M Suarez, Daniel Apolinar, Haiber Arias and Francisco J Londoño Derechos de uso : CC BY En línea : https://www.opastpublishers.com/open-access-articles/posttraumatic-vasospasm-aft [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Post-traumatic vasospasm after mild brain trauma, a lesson learned [documento electrónico] / Francisco Javier Londoño Ocampo,  . - 2022. Obra : Advances in Neurology and Neuroscience Idioma : Inglés (eng) Palabras clave : Posttraumatic Vasospasm  Traumatic Brain Injury  Mild Brain Trauma  Balloon Angioplasty  Cerebral Ischemia Resumen : Background: Post-traumatic vasospasm is a frequent secondary injury in patients with traumatic brain injury, occurring in up to 63% of patients and with associated deleterious consequences. Most studies have reported post-traumatic vasospasm in patients with severe or moderate brain trauma; however, there are documented cases of post-traumatic vasospasm in patients with mild traumatic brain injury that support a more aggressive search to prevent deleterious neurological outcomes. Observation(s): The pertinent literature has been reviewed, and an exemplary case has been reported (post-traumatic vasospasm associated with mild brain trauma in an adult patient that subsequently transformed into cerebral ischemia that was managed with endovascular therapy and oral nimodipine without subsequent neurological deterioration). To date, only 4 cases have been described, to our knowledge this is the first literature review so far. Lessons: Given the possibility of post-traumatic vasospasm associated with mild brain trauma, the authors believe that GCS score alone may be an inadequate risk predictor of symptomatic cerebral vasospasm and a more aggressive search should be performed in patients with mild trauma who present with neurological deterioration without apparent cause. Mención de responsabilidad : Felipe Gutierrez Pineda, Mauro M Suarez, Daniel Apolinar, Haiber Arias and Francisco J Londoño Derechos de uso : CC BY En línea : https://www.opastpublishers.com/open-access-articles/posttraumatic-vasospasm-aft [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis

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Acute visual loss related to retinal vascular occlusion secondary to visual pathway primary glioblastoma / Francisco Javier Londoño Ocampo ; Feliza Restrepo Restrepo ; Lina García ; Beatriz Eugenia Pineda Arrieta ; Beatriz Elena Lopera Marín ; Germán Alonso Reyes Botero  

Público ISBD Título : Acute visual loss related to retinal vascular occlusion secondary to visual pathway primary glioblastoma Tipo de documento : documento electrónico Autores : Francisco Javier Londoño Ocampo, ; Feliza Restrepo Restrepo, ; Lina García, ; Beatriz Eugenia Pineda Arrieta, ; Beatriz Elena Lopera Marín, ; Germán Alonso Reyes Botero, Fecha de publicación : 2021 Títulos uniformes : Journal of Neuro-Ophthalmology Idioma : Inglés (eng) Mención de responsabilidad : Muñoz-Cardona, Marta L. MD; Llano-Naranjo, Yuliana MD; Londoño-Ocampo, Francisco MD; Preciado-Mesa, Esteban E. MD; Restrepo, Feliza MD; García, Lina MD; Pineda-Arrieta, Beatriz MD; Lopera-Marín, Beatriz MD; Reyes-Botero, Germán A. MD Referencia : J Neuroophthalmol. 2021 Jun 1;41(2):e142-e144. DOI (Digital Object Identifier) : 10.1097/WNO.0000000000000957 PMID : 32701755 En línea : https://journals.lww.com/jneuro-ophthalmology/Citation/9000/Acute_Visual_Loss_Re [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Acute visual loss related to retinal vascular occlusion secondary to visual pathway primary glioblastoma [documento electrónico] / Francisco Javier Londoño Ocampo, ; Feliza Restrepo Restrepo, ; Lina García, ; Beatriz Eugenia Pineda Arrieta, ; Beatriz Elena Lopera Marín, ; Germán Alonso Reyes Botero,  . - 2021. Obra : Journal of Neuro-Ophthalmology Idioma : Inglés (eng) Mención de responsabilidad : Muñoz-Cardona, Marta L. MD; Llano-Naranjo, Yuliana MD; Londoño-Ocampo, Francisco MD; Preciado-Mesa, Esteban E. MD; Restrepo, Feliza MD; García, Lina MD; Pineda-Arrieta, Beatriz MD; Lopera-Marín, Beatriz MD; Reyes-Botero, Germán A. MD Referencia : J Neuroophthalmol. 2021 Jun 1;41(2):e142-e144. DOI (Digital Object Identifier) : 10.1097/WNO.0000000000000957 PMID : 32701755 En línea : https://journals.lww.com/jneuro-ophthalmology/Citation/9000/Acute_Visual_Loss_Re [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis

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Neurocysticercosis, meningioma, and silent corticotroph pituitary adenoma in a 61-year-old woman / Francisco Javier Londoño Ocampo ; María del Pilar Ramírez ; Juan E. Restrepo ; Luis Vicente Syro Moreno    

Público ISBD Título : Neurocysticercosis, meningioma, and silent corticotroph pituitary adenoma in a 61-year-old woman Tipo de documento : documento electrónico Autores : Francisco Javier Londoño Ocampo, ; María del Pilar Ramírez, ; Juan E. Restrepo, ; Luis Vicente Syro Moreno, Fecha de publicación : 2012 Títulos uniformes : Case Reports in Pathology Idioma : Inglés (eng) Resumen : We report here the case of a 61-year-old woman who presented with hydrocephalus and cystic and solid lesions in sella turcica, suprasellar areas, and third ventricle. After ventriculoperitoneal shunt she developed cognitive changes and the cystic lesions enlarged. Magnetic resonance imaging (MRI) demonstrated multiple cysts and a solid lesion in the sella and around the anterior clinoid process. With diagnosis of neurocysticercosis she underwent craniotomy. Pathologic examination documented two different lesions: viable and dead cysticerci with inflaming infiltration and a left anterior clinoidal meningioma. At the second surgery, six weeks later via transnasal transsphenoidal approach a silent corticotroph pituitary adenoma was removed which was studied by histology, immunohistochemistry, and electron microscopy. To our knowledge, the occurrence of these three different lesions in the sellar area was not described before. Mención de responsabilidad : Maria Del Pilar Ramirez, Juan E Restrepo, Luis V Syro, Fabio Rotondo, Francisco J Londoño, Luis C Penagos, Humberto Uribe, Eva Horvath, Kalman Kovacs Referencia : Case Rep Pathol. 2012;2012:340840. DOI (Digital Object Identifier) : 10.1155/2012/340840 PMID : 23346440 Derechos de uso : CC BY En línea : https://www.hindawi.com/journals/cripa/2012/340840/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Neurocysticercosis, meningioma, and silent corticotroph pituitary adenoma in a 61-year-old woman [documento electrónico] / Francisco Javier Londoño Ocampo, ; María del Pilar Ramírez, ; Juan E. Restrepo, ; Luis Vicente Syro Moreno,  . - 2012. Obra : Case Reports in Pathology Idioma : Inglés (eng) Resumen : We report here the case of a 61-year-old woman who presented with hydrocephalus and cystic and solid lesions in sella turcica, suprasellar areas, and third ventricle. After ventriculoperitoneal shunt she developed cognitive changes and the cystic lesions enlarged. Magnetic resonance imaging (MRI) demonstrated multiple cysts and a solid lesion in the sella and around the anterior clinoid process. With diagnosis of neurocysticercosis she underwent craniotomy. Pathologic examination documented two different lesions: viable and dead cysticerci with inflaming infiltration and a left anterior clinoidal meningioma. At the second surgery, six weeks later via transnasal transsphenoidal approach a silent corticotroph pituitary adenoma was removed which was studied by histology, immunohistochemistry, and electron microscopy. To our knowledge, the occurrence of these three different lesions in the sellar area was not described before. Mención de responsabilidad : Maria Del Pilar Ramirez, Juan E Restrepo, Luis V Syro, Fabio Rotondo, Francisco J Londoño, Luis C Penagos, Humberto Uribe, Eva Horvath, Kalman Kovacs Referencia : Case Rep Pathol. 2012;2012:340840. DOI (Digital Object Identifier) : 10.1155/2012/340840 PMID : 23346440 Derechos de uso : CC BY En línea : https://www.hindawi.com/journals/cripa/2012/340840/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis

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