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Autor Luz Elena Cano Restrepo |
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Inhibitory effect of deferoxamine or macrophage activation on transformation of Paracoccidioides brasiliensis conidia ingested by macrophages: reversal by holotransferrin / Luz Elena Cano Restrepo ; Beatriz Gómez ; Ángela Restrepo Moreno
Título : Inhibitory effect of deferoxamine or macrophage activation on transformation of Paracoccidioides brasiliensis conidia ingested by macrophages: reversal by holotransferrin Tipo de documento : documento electrónico Autores : Luz Elena Cano Restrepo, ; Beatriz Gómez, ; Ángela Restrepo Moreno, Fecha de publicación : 1994 Títulos uniformes : Infection and Immunity Idioma : Inglés (eng) Resumen : Conidia of P. brasiliensis ingested by murine macrophages at 37 degrees C showed enhanced transformation to yeast cells and further intracellular growth compared with conidia in culture medium alone. Treatment of macrophages with the iron chelator deferoxamine inhibited the intracellular conidium-to-yeast transformation. Cytokine-activated macrophages could also exert this inhibitory effect. Holotransferrin reversed the inhibitory effect of either deferoxamine or activated macrophages on intracellular conidium-to-yeast transformation. These results indicate that iron restriction is one of the mechanisms by which activated macrophages control the intracellular transformation of ingested conidia and growth of yeast cells. Mención de responsabilidad : L E Cano, B Gomez, E Brummer, A Restrepo, D A Stevens Referencia : Infect Immun. 1994 Apr;62(4):1494-5. PMID : 8132359 En línea : https://iai.asm.org/content/62/4/1494 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4375 Inhibitory effect of deferoxamine or macrophage activation on transformation of Paracoccidioides brasiliensis conidia ingested by macrophages: reversal by holotransferrin [documento electrónico] / Luz Elena Cano Restrepo, ; Beatriz Gómez, ; Ángela Restrepo Moreno, . - 1994.
Obra : Infection and Immunity
Idioma : Inglés (eng)
Resumen : Conidia of P. brasiliensis ingested by murine macrophages at 37 degrees C showed enhanced transformation to yeast cells and further intracellular growth compared with conidia in culture medium alone. Treatment of macrophages with the iron chelator deferoxamine inhibited the intracellular conidium-to-yeast transformation. Cytokine-activated macrophages could also exert this inhibitory effect. Holotransferrin reversed the inhibitory effect of either deferoxamine or activated macrophages on intracellular conidium-to-yeast transformation. These results indicate that iron restriction is one of the mechanisms by which activated macrophages control the intracellular transformation of ingested conidia and growth of yeast cells. Mención de responsabilidad : L E Cano, B Gomez, E Brummer, A Restrepo, D A Stevens Referencia : Infect Immun. 1994 Apr;62(4):1494-5. PMID : 8132359 En línea : https://iai.asm.org/content/62/4/1494 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4375 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000875 AC-1994-002 Archivo digital Producción Científica Artículos científicos Disponible Disseminated adiaspiromycosis in a patient with AIDS / Luz Elena Cano Restrepo ; Ángela Restrepo Moreno
Título : Disseminated adiaspiromycosis in a patient with AIDS Tipo de documento : documento electrónico Autores : Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, Fecha de publicación : 1993 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : A case of disseminated adiaspiromycosis in an AIDS patient is described. The most notable characteristic of the infection was the extensive osteomyelitis exhibited by the patient. Positive cultures for Chrysosporium parvum var. parvum were obtained from pus taken from a lesion of the wrist during surgery as well as from sputum samples and a bone marrow aspirate. Treatment with amphotericin B controlled the fungal infection. Mención de responsabilidad : E. Echavarria, E.L. Cano, A. Restrepo Referencia : J Med Vet Mycol. 1993;31(1):91-7. DOI (Digital Object Identifier) : 10.1080/02681219380000101 PMID : 8483061 En línea : https://academic.oup.com/mmy/article-abstract/31/1/91/942394 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4369 Disseminated adiaspiromycosis in a patient with AIDS [documento electrónico] / Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, . - 1993.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : A case of disseminated adiaspiromycosis in an AIDS patient is described. The most notable characteristic of the infection was the extensive osteomyelitis exhibited by the patient. Positive cultures for Chrysosporium parvum var. parvum were obtained from pus taken from a lesion of the wrist during surgery as well as from sputum samples and a bone marrow aspirate. Treatment with amphotericin B controlled the fungal infection. Mención de responsabilidad : E. Echavarria, E.L. Cano, A. Restrepo Referencia : J Med Vet Mycol. 1993;31(1):91-7. DOI (Digital Object Identifier) : 10.1080/02681219380000101 PMID : 8483061 En línea : https://academic.oup.com/mmy/article-abstract/31/1/91/942394 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4369 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000869 AC-1993-002 Archivo digital Producción Científica Artículos científicos Disponible Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages / Luz Elena Cano Restrepo ; Ángela Restrepo Moreno
Título : Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages Tipo de documento : documento electrónico Autores : Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, Fecha de publicación : 1992 Títulos uniformes : Infection and Immunity Idioma : Inglés (eng) Resumen : Conidia ingested by resident macrophages had an enhanced percentage of transformation to yeast cells compared with those in culture medium without macrophages. The yeast cells subsequently grew intracellularly by budding. Macrophages treated with cytokines from antigen-stimulated spleen cells from immunized mice significantly inhibited transformation of ingested conidia. Mención de responsabilidad : L E Cano, E Brummer, D A Stevens, A Restrepo Referencia : Infect Immun. 1992 May;60(5):2096-100. PMID : 1563800 En línea : https://iai.asm.org/content/60/5/2096.long Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4363 Fate of conidia of Paracoccidioides brasiliensis after ingestion by resident macrophages or cytokine-treated macrophages [documento electrónico] / Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, . - 1992.
Obra : Infection and Immunity
Idioma : Inglés (eng)
Resumen : Conidia ingested by resident macrophages had an enhanced percentage of transformation to yeast cells compared with those in culture medium without macrophages. The yeast cells subsequently grew intracellularly by budding. Macrophages treated with cytokines from antigen-stimulated spleen cells from immunized mice significantly inhibited transformation of ingested conidia. Mención de responsabilidad : L E Cano, E Brummer, D A Stevens, A Restrepo Referencia : Infect Immun. 1992 May;60(5):2096-100. PMID : 1563800 En línea : https://iai.asm.org/content/60/5/2096.long Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4363 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000863 AC-1992-002 Archivo digital Producción Científica Artículos científicos Disponible Killing of Paracoccidioides brasiliensis conidia by pulmonary macrophages and the effect of cytokines / Luz Elena Cano Restrepo ; R. Arango ; Maria E. Salazar ; Ángela Restrepo Moreno
Título : Killing of Paracoccidioides brasiliensis conidia by pulmonary macrophages and the effect of cytokines Tipo de documento : documento electrónico Autores : Luz Elena Cano Restrepo, ; R. Arango, ; Maria E. Salazar, ; Ángela Restrepo Moreno, Fecha de publicación : 1992 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : The ability of conidia, the infectious form of the dimorphic fungus Paracoccidioides brasiliensis, to be killed in vitro by murine pulmonary macrophages was studied. Mice were immunized by intravenous injection of killed conidia, which resulted in cellular immunity demonstrated by delayed type hypersensitivity in vivo and macrophage migration inhibition factor production in vitro. Resident pulmonary macrophages from non-immune mice were able to significantly kill the conidia (28%). Such macrophages treated with supernatants (cytokines) from antigen-stimulated immune mononuclears had a markedly enhanced ability to kill conidia (73%). These results show that activated pulmonary macrophages are potent killers of conidia of P. brasiliensis and that immune mononuclears play a role in activation of macrophages. Activated macrophages may be important for pulmonary defense against the initial stages of infection with this fungus. Mención de responsabilidad : L.E. Cano, R. Arango, M.E. Salazar, E. Brummer, D.A. Stevens & A. Restrepo Referencia : J Med Vet Mycol. 1992;30(2):161-8. DOI (Digital Object Identifier) : 10.1080/02681219280000211 PMID : 1588466 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219280000211 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4365 Killing of Paracoccidioides brasiliensis conidia by pulmonary macrophages and the effect of cytokines [documento electrónico] / Luz Elena Cano Restrepo, ; R. Arango, ; Maria E. Salazar, ; Ángela Restrepo Moreno, . - 1992.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : The ability of conidia, the infectious form of the dimorphic fungus Paracoccidioides brasiliensis, to be killed in vitro by murine pulmonary macrophages was studied. Mice were immunized by intravenous injection of killed conidia, which resulted in cellular immunity demonstrated by delayed type hypersensitivity in vivo and macrophage migration inhibition factor production in vitro. Resident pulmonary macrophages from non-immune mice were able to significantly kill the conidia (28%). Such macrophages treated with supernatants (cytokines) from antigen-stimulated immune mononuclears had a markedly enhanced ability to kill conidia (73%). These results show that activated pulmonary macrophages are potent killers of conidia of P. brasiliensis and that immune mononuclears play a role in activation of macrophages. Activated macrophages may be important for pulmonary defense against the initial stages of infection with this fungus. Mención de responsabilidad : L.E. Cano, R. Arango, M.E. Salazar, E. Brummer, D.A. Stevens & A. Restrepo Referencia : J Med Vet Mycol. 1992;30(2):161-8. DOI (Digital Object Identifier) : 10.1080/02681219280000211 PMID : 1588466 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219280000211 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4365 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000865 AC-1992-004 Archivo digital Producción Científica Artículos científicos Disponible Electron microscopic study of conidia produced by the mycelium of Paracoccidioides brasiliensis / Maria E. Salazar ; Luz Elena Cano Restrepo ; Ángela Restrepo Moreno
Título : Electron microscopic study of conidia produced by the mycelium of Paracoccidioides brasiliensis Tipo de documento : documento electrónico Autores : Maria E. Salazar, ; Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, Fecha de publicación : 1991 Títulos uniformes : Mycopathologia Idioma : Inglés (eng) Palabras clave : Paracoccidioidomycosis mycelium conidia ultrastructure Resumen : The ultrastructure of asexual spores (conidia) produced by the mycelial form of Paracoccidioides brasiliensis was studied for the first time with transmission electron microscopy, using thin sections of aldehyde-osmium-fixed and epoxy-resin-embedded samples. The various types of conidia observed in the sections correlated well with previous light-microscopic descriptions. These types were intercalary or apical conidia, depending on their location along the originating hyphae. As in previous studies they were characterized as arthroconidia, aleuriospores and sessile or pedunculate pyriform conidia. The sporogenous cells were clearly distinguished from hyphal cells by the thickness and appearance of their cell walls. Copious fibrillar material (glycocalyx) detected at the cell surface was stained with ruthenium red during the fixation process. Typical subcellular organelles (nucleus, nucleolus, mitochondria, ribosomes, etc) were found in most of the sections. It was concluded that the spores produced by the mycelial phase of P. brasiliensis possess all attributes of viable and physiologically competent eukaryotic cells. Mención de responsabilidad : Mercedes R. Edwards, M. E. Salazar, W. A. Samsonoff, L. E. Cano, G. A. Ostrander & A. Restrepo Referencia : Mycopathologia. 1991 Jun;114(3):169-77. DOI (Digital Object Identifier) : 10.1007/BF00437210 PMID : 1886643 En línea : https://link.springer.com/article/10.1007/BF00437210 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4360 Electron microscopic study of conidia produced by the mycelium of Paracoccidioides brasiliensis [documento electrónico] / Maria E. Salazar, ; Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, . - 1991.
Obra : Mycopathologia
Idioma : Inglés (eng)
Palabras clave : Paracoccidioidomycosis mycelium conidia ultrastructure Resumen : The ultrastructure of asexual spores (conidia) produced by the mycelial form of Paracoccidioides brasiliensis was studied for the first time with transmission electron microscopy, using thin sections of aldehyde-osmium-fixed and epoxy-resin-embedded samples. The various types of conidia observed in the sections correlated well with previous light-microscopic descriptions. These types were intercalary or apical conidia, depending on their location along the originating hyphae. As in previous studies they were characterized as arthroconidia, aleuriospores and sessile or pedunculate pyriform conidia. The sporogenous cells were clearly distinguished from hyphal cells by the thickness and appearance of their cell walls. Copious fibrillar material (glycocalyx) detected at the cell surface was stained with ruthenium red during the fixation process. Typical subcellular organelles (nucleus, nucleolus, mitochondria, ribosomes, etc) were found in most of the sections. It was concluded that the spores produced by the mycelial phase of P. brasiliensis possess all attributes of viable and physiologically competent eukaryotic cells. Mención de responsabilidad : Mercedes R. Edwards, M. E. Salazar, W. A. Samsonoff, L. E. Cano, G. A. Ostrander & A. Restrepo Referencia : Mycopathologia. 1991 Jun;114(3):169-77. DOI (Digital Object Identifier) : 10.1007/BF00437210 PMID : 1886643 En línea : https://link.springer.com/article/10.1007/BF00437210 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4360 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000860 AC-1991-002 Archivo digital Producción Científica Artículos científicos Disponible Scanning electron microscopy of the conidia produced by the mycelial form of Paracoccidioides brasiliensis / Maria E. Salazar ; Ángela Restrepo Moreno ; Luz Elena Cano RestrepoPermalinkPredictive value of serologic tests in the diagnosis and follow-up of patients with paracoccidioidomycosis / Luz Elena Cano Restrepo ; Ángela Restrepo MorenoPermalinkAn evaluation of the enzyme-linked immunoabsorbent assay (ELISA) for quantitation of antibodies to paracoccidioides brasiliensis / Luz Elena Cano Restrepo ; Ángela Restrepo MorenoPermalinkWater as a substrate for the development of Paracoccidiodes brasiliensis mycelial form / Catalina de Bedout Gómez ; Luz Elena Cano Restrepo ; Ángela María Tabares Velásquez ; Ángela Restrepo MorenoPermalinkA yeast-derived antigen from paracoccidioides brasiliensis useful for serologic testing / Ángela Restrepo Moreno ; Luz Elena Cano Restrepo ; María Teresa OchoaPermalinkEstrogens inhibit mycelium-to-yeast transformation in the fungus Paracoccidioides brasiliensis: Implications for resistance of females to Paracoccidioidomycosis / Ángela Restrepo Moreno ; Maria E. Salazar ; Luz Elena Cano RestrepoPermalinkA comparison of mycelial filtrate - and yeast lysate - paracoccidioidin in patients with paracoccidioidomycosis / Ángela Restrepo Moreno ; Luz Elena Cano Restrepo ; Ángela María Tabares VelásquezPermalinkComparison of various techniques for determining viability of Paracoccidioides brasiliensis yeast-form cells / Ángela Restrepo Moreno ; Luz Elena Cano Restrepo ; Catalina de Bedout GómezPermalinkRecovery of fungi from seeded sputum samples: Effect of culture media and digestion procedures / Ángela Restrepo Moreno ; Luz Elena Cano RestrepoPermalink