In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides / Ángela Restrepo Moreno ; María D. Arango  

Público ISBD Título : In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides Tipo de documento : documento electrónico Autores : Ángela Restrepo Moreno, ; María D. Arango, Fecha de publicación : 1980 Títulos uniformes : Antimicrobial Agents and Chemotherapy Idioma : Inglés (eng) Resumen : A total of 60 clinical isolates of Paracoccidioides brasiliensis were tested for susceptibility to sulfadiazine and sulfadimethoxyne by the agar dilution technique. A modification of the Mueller-Hinton medium was devised which gave good growth of the yeast form. The minimum inhibitory concentrations for only 51.6% of the isolates were in the range of the recommended blood serum concentration (50 micrograms/ml). For 6 to 8% of the isolates, the minimum inhibitory concentrations were above 200 micrograms of both sulfadiazine and sulfadimethoxyne per ml. A significant decreases in susceptibility was demonstrated for one isolate obtained from a patient relapsing during sulfonamide therapy. Mención de responsabilidad : A Restrepo, M D Arango Referencia : Antimicrob Agents Chemother. 1980 Jul;18(1):190-4. DOI (Digital Object Identifier) : 10.1128/AAC.18.1.190 PMID : 7416744 En línea : https://aac.asm.org/content/18/1/190 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4317 In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides [documento electrónico] / Ángela Restrepo Moreno, ; María D. Arango,  . - 1980. Obra : Antimicrobial Agents and Chemotherapy Idioma : Inglés (eng) Resumen : A total of 60 clinical isolates of Paracoccidioides brasiliensis were tested for susceptibility to sulfadiazine and sulfadimethoxyne by the agar dilution technique. A modification of the Mueller-Hinton medium was devised which gave good growth of the yeast form. The minimum inhibitory concentrations for only 51.6% of the isolates were in the range of the recommended blood serum concentration (50 micrograms/ml). For 6 to 8% of the isolates, the minimum inhibitory concentrations were above 200 micrograms of both sulfadiazine and sulfadimethoxyne per ml. A significant decreases in susceptibility was demonstrated for one isolate obtained from a patient relapsing during sulfonamide therapy. Mención de responsabilidad : A Restrepo, M D Arango Referencia : Antimicrob Agents Chemother. 1980 Jul;18(1):190-4. DOI (Digital Object Identifier) : 10.1128/AAC.18.1.190 PMID : 7416744 En línea : https://aac.asm.org/content/18/1/190 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4317

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