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					| Título : | In vitro evaluation of lomefloxacin activity in Colombia |  
					| Tipo de documento : | documento electrónico |  
					| Autores : | Hugo Trujillo Soto,  ; Gloria Isabel Mejía de Rodríguez,  ; Lucero Castrillón de P.,  ; C. Gómez, |  
					| Fecha de publicación : | 1989 |  
					| Títulos uniformes : | Diagnostic Microbiology and Infectious Disease 
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					| Idioma : | Inglés (eng) |  
					| Resumen : | As part of the worldwide in vitro program to determine the antimicrobial activity of lomefloxacin, our study tested susceptibility of bacterial isolates from hospitals in Medellin, Colombia. A total of 504 bacterial isolates were obtained from patients at three different centers. For Enterobacteriaceae, 0.5 μg/ml inhibited 100% of the indole-positive Proteus and Salmonella spp.; 1 μg/ml inhibited 100% of Shigella and Citrobacter, 2 μg/ml inhibited 100% of Enterobacter spp., E. coli, Proteus mirabilis, and Serratia marcescens isolates tested. The MIC90 for Klebsiella spp. and Pseudomonas spp. was 4 μg/ml. The MIC90 was 4 μg/ml for S. aureus and 2 μg/ml for S. epidemidis and S. saprophyticus. The MIC90 of Streptococcus spp. were ⩽4 μg/ml for all isolates tested. Considering that 97.8% were susceptible to concentrations of ⩽4 μg/ml of lomefloxacin, this new quinolone offers potential in the therapy of a variety of systemic infections, especially in patients with multiply resistant pathogens. |  
					| Mención de responsabilidad : | H Trujillo, G I Mejia, L Castrillon, C Gomez |  
					| Referencia : | Diagn Microbiol Infect Dis. 1989 May-Jun;12(3 Suppl):51S-52S |  
					| DOI (Digital Object Identifier) : | 10.1016/0732-8893(89)90066-7 |  
					| PMID : | 2791498 |  
					| En línea : | https://linkinghub.elsevier.com/retrieve/pii/0732889389900667 |  
					| Enlace permanente : | https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis | 
In vitro evaluation of lomefloxacin activity in Colombia [documento electrónico] / Hugo Trujillo Soto ,  ; Gloria Isabel Mejía de Rodríguez ,  ; Lucero Castrillón de P. ,  ; C. Gómez ,  . - 1989.Obra  :  Diagnostic Microbiology and Infectious DiseaseIdioma  : Inglés (eng ) 
					| Resumen : | As part of the worldwide in vitro program to determine the antimicrobial activity of lomefloxacin, our study tested susceptibility of bacterial isolates from hospitals in Medellin, Colombia. A total of 504 bacterial isolates were obtained from patients at three different centers. For Enterobacteriaceae, 0.5 μg/ml inhibited 100% of the indole-positive Proteus and Salmonella spp.; 1 μg/ml inhibited 100% of Shigella and Citrobacter, 2 μg/ml inhibited 100% of Enterobacter spp., E. coli, Proteus mirabilis, and Serratia marcescens isolates tested. The MIC90 for Klebsiella spp. and Pseudomonas spp. was 4 μg/ml. The MIC90 was 4 μg/ml for S. aureus and 2 μg/ml for S. epidemidis and S. saprophyticus. The MIC90 of Streptococcus spp. were ⩽4 μg/ml for all isolates tested. Considering that 97.8% were susceptible to concentrations of ⩽4 μg/ml of lomefloxacin, this new quinolone offers potential in the therapy of a variety of systemic infections, especially in patients with multiply resistant pathogens. |  
					| Mención de responsabilidad : | H Trujillo, G I Mejia, L Castrillon, C Gomez |  
					| Referencia : | Diagn Microbiol Infect Dis. 1989 May-Jun;12(3 Suppl):51S-52S |  
					| DOI (Digital Object Identifier) : | 10.1016/0732-8893(89)90066-7 |  
					| PMID : | 2791498 |  
					| En línea : | https://linkinghub.elsevier.com/retrieve/pii/0732889389900667 |  
					| Enlace permanente : | https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis | 
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