First three cases of cat-associated zoonotic cutaneous sporotrichosis in Colombia / María Elizabeth Gaviria Barrera ; Luz Adriana Vásquez Ochoa  

Público ISBD Título : First three cases of cat-associated zoonotic cutaneous sporotrichosis in Colombia Tipo de documento : documento electrónico Autores : María Elizabeth Gaviria Barrera, ; Luz Adriana Vásquez Ochoa, Fecha de publicación : 2022 Títulos uniformes : International Journal of Dermatology Idioma : Inglés (eng) Resumen : Background: Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The route of entry of the causative agent is direct inoculation by skin trauma, generally with decaying wood and other vegetation. However, cat-transmitted sporotrichosis has become more relevant in recent decades especially in South America. Until now, there are no case reports of cat-transmitted sporotrichosis in Colombia. Case report: We present three cases of cutaneous sporotrichosis after the scratches of an ill cat, in the feline's owners and its veterinarian, confirmed by culture and PCR, where S. schenckii sensu stricto was isolated and typified. Conclusions: Cat-transmitted sporotrichosis is becoming more relevant in recent decades due to its potential to generate epidemics and become a public health problem. In addition, since the associated species are more virulent, the disease has more aggressive behavior. In Colombia, this is the first case series of cat-transmitted cutaneous sporotrichosis. Mención de responsabilidad : Simon Gallo MD, Camilo Arias-Rodriguez MD, Erika A. Sánchez-Cifuentes MSc, Catalina Santa-Vélez MD, Isabel Larrañaga-Piñeres MD, Maria E. Gaviria-Barrera MD, Luz A. Vásquez-Ochoa MD, Daniel Montoya MD, Maria del P. Jiménez-Alzate MD, MSc, PhD Referencia : Int J Dermatol. 2022 Oct;61(10):1276-1279. DOI (Digital Object Identifier) : 10.1111/ijd.16377 PMID : 35959537 En línea : https://onlinelibrary.wiley.com/doi/10.1111/ijd.16377 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6087 First three cases of cat-associated zoonotic cutaneous sporotrichosis in Colombia [documento electrónico] / María Elizabeth Gaviria Barrera, ; Luz Adriana Vásquez Ochoa,  . - 2022. Obra : International Journal of Dermatology Idioma : Inglés (eng) Resumen : Background: Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The route of entry of the causative agent is direct inoculation by skin trauma, generally with decaying wood and other vegetation. However, cat-transmitted sporotrichosis has become more relevant in recent decades especially in South America. Until now, there are no case reports of cat-transmitted sporotrichosis in Colombia. Case report: We present three cases of cutaneous sporotrichosis after the scratches of an ill cat, in the feline's owners and its veterinarian, confirmed by culture and PCR, where S. schenckii sensu stricto was isolated and typified. Conclusions: Cat-transmitted sporotrichosis is becoming more relevant in recent decades due to its potential to generate epidemics and become a public health problem. In addition, since the associated species are more virulent, the disease has more aggressive behavior. In Colombia, this is the first case series of cat-transmitted cutaneous sporotrichosis. Mención de responsabilidad : Simon Gallo MD, Camilo Arias-Rodriguez MD, Erika A. Sánchez-Cifuentes MSc, Catalina Santa-Vélez MD, Isabel Larrañaga-Piñeres MD, Maria E. Gaviria-Barrera MD, Luz A. Vásquez-Ochoa MD, Daniel Montoya MD, Maria del P. Jiménez-Alzate MD, MSc, PhD Referencia : Int J Dermatol. 2022 Oct;61(10):1276-1279. DOI (Digital Object Identifier) : 10.1111/ijd.16377 PMID : 35959537 En línea : https://onlinelibrary.wiley.com/doi/10.1111/ijd.16377 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6087

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Immunopathologic study of erythema dyschromicum perstans (ashy dermatosis) / Luz Adriana Vásquez Ochoa  

Público ISBD Título : Immunopathologic study of erythema dyschromicum perstans (ashy dermatosis) Tipo de documento : documento electrónico Autores : Luz Adriana Vásquez Ochoa, Fecha de publicación : 2006 Títulos uniformes : International Journal of Dermatology Idioma : Inglés (eng) Resumen : Erythema dyschromicum perstans (EDP) is a pigmentary disease of unknown etiology in which damage to basal cells is thought to be mediated by adhesion molecules. The aim of this study was to characterize the histopathology and immunopathology of EDP. Forty-three patients from Medellín, Colombia, with the diagnosis of EDP were evaluated. Skin biopsy specimens were obtained for histopathology and immunohistochemistry, using monoclonal antibodies directed against the following markers: CD4, CD8, CD56, CD1a, CD68, CLA, HLA-DR, ICAM-1 and LFA-1alpha. A dermal lymphocytic infiltrate was observed in all cases, with a perivascular location in 86%. Other histologic features included melanophages in all specimens, vacuolization of the basement membrane zone (BMZ) 58% and exocytosis of lymphocytes (53.5%). The mean number of total leukocytes was 1510 cells mm-2 of tissue. There was a predominance of CD8+ T lymphocytes in the dermis and HLA-DR+, ICAM-1+ keratinocytes in the epidermis. Exocytosis of cutaneous lymphocyte antigen (CLA)+cells was observed in areas of BMZ damage, suggesting that response to antigenic stimulation may play a role in the development of EDP. Mención de responsabilidad : A. Vásquez‐Ochoa Luz MD M. Isaza‐Guzmán Diana MSc Beatriz Orozco‐Mora MD Rodrigo Restrepo‐Molina MD Judith Trujillo‐Perez BLC J. Tapia Félix MPh Referencia : Int J Dermatol. 2006 Aug;45(8):937-41. PMID : 16911378 En línea : https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-4632.2006.02893.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4414 Immunopathologic study of erythema dyschromicum perstans (ashy dermatosis) [documento electrónico] / Luz Adriana Vásquez Ochoa,  . - 2006. Obra : International Journal of Dermatology Idioma : Inglés (eng) Resumen : Erythema dyschromicum perstans (EDP) is a pigmentary disease of unknown etiology in which damage to basal cells is thought to be mediated by adhesion molecules. The aim of this study was to characterize the histopathology and immunopathology of EDP. Forty-three patients from Medellín, Colombia, with the diagnosis of EDP were evaluated. Skin biopsy specimens were obtained for histopathology and immunohistochemistry, using monoclonal antibodies directed against the following markers: CD4, CD8, CD56, CD1a, CD68, CLA, HLA-DR, ICAM-1 and LFA-1alpha. A dermal lymphocytic infiltrate was observed in all cases, with a perivascular location in 86%. Other histologic features included melanophages in all specimens, vacuolization of the basement membrane zone (BMZ) 58% and exocytosis of lymphocytes (53.5%). The mean number of total leukocytes was 1510 cells mm-2 of tissue. There was a predominance of CD8+ T lymphocytes in the dermis and HLA-DR+, ICAM-1+ keratinocytes in the epidermis. Exocytosis of cutaneous lymphocyte antigen (CLA)+cells was observed in areas of BMZ damage, suggesting that response to antigenic stimulation may play a role in the development of EDP. Mención de responsabilidad : A. Vásquez‐Ochoa Luz MD M. Isaza‐Guzmán Diana MSc Beatriz Orozco‐Mora MD Rodrigo Restrepo‐Molina MD Judith Trujillo‐Perez BLC J. Tapia Félix MPh Referencia : Int J Dermatol. 2006 Aug;45(8):937-41. PMID : 16911378 En línea : https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-4632.2006.02893.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4414

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Saperconazole in the treatment of systemic and subcutaneous mycoses / Liliana Franco R. ; Iván Gómez ; Ángela Restrepo Moreno  

Público ISBD Título : Saperconazole in the treatment of systemic and subcutaneous mycoses Tipo de documento : documento electrónico Autores : Liliana Franco R., ; Iván Gómez, ; Ángela Restrepo Moreno, Fecha de publicación : 1992 Títulos uniformes : International Journal of Dermatology Idioma : Inglés (eng) Resumen : In a 2‐year period, 30 patients with culture‐proven mycoses (chromoblastomycosis, sporotrichosis, and paracoccid‐ioidomycosis) were treated with the new orally administered triazole, saperconazole (SPZ) (R66905). The daily dose varied from 100 to 200 mg. All patients responded to treatment; the mean time required to heal the lesions and convert the cultures to negative was 3.5 months for sporotrichosis, 4.6 for paracoccidioidomycosis, and 9.0 for chromoblastomycosis. Evaluation by a scoring system indicated that 36.6% of the patients achieved complete resolution of the pretherapy abnormalities, while the remaining (63.3%) experienced major improvement. No colateral effects were reported; there were no bone‐marrow or liver toxicities. SPZ is an effective drug for the treatment of the above‐mentioned mycoses and appears to be suitable for the control of chromoblastomycosis. Mención de responsabilidad : Liliana Franco M.D. Ivan Gomez M.D. Angela Restrepo Ph.D. Referencia : Int J Dermatol. 1992 Oct;31(10):725-9. DOI (Digital Object Identifier) : 10.1111/j.1365-4362.1992.tb01384.x PMID : 1399205 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-4362.1992.tb01384.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4362 Saperconazole in the treatment of systemic and subcutaneous mycoses [documento electrónico] / Liliana Franco R., ; Iván Gómez, ; Ángela Restrepo Moreno,  . - 1992. Obra : International Journal of Dermatology Idioma : Inglés (eng) Resumen : In a 2‐year period, 30 patients with culture‐proven mycoses (chromoblastomycosis, sporotrichosis, and paracoccid‐ioidomycosis) were treated with the new orally administered triazole, saperconazole (SPZ) (R66905). The daily dose varied from 100 to 200 mg. All patients responded to treatment; the mean time required to heal the lesions and convert the cultures to negative was 3.5 months for sporotrichosis, 4.6 for paracoccidioidomycosis, and 9.0 for chromoblastomycosis. Evaluation by a scoring system indicated that 36.6% of the patients achieved complete resolution of the pretherapy abnormalities, while the remaining (63.3%) experienced major improvement. No colateral effects were reported; there were no bone‐marrow or liver toxicities. SPZ is an effective drug for the treatment of the above‐mentioned mycoses and appears to be suitable for the control of chromoblastomycosis. Mención de responsabilidad : Liliana Franco M.D. Ivan Gomez M.D. Angela Restrepo Ph.D. Referencia : Int J Dermatol. 1992 Oct;31(10):725-9. DOI (Digital Object Identifier) : 10.1111/j.1365-4362.1992.tb01384.x PMID : 1399205 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-4362.1992.tb01384.x Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4362

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