| Título : |
Undifferentiated sarcoma of the sellar region |
| Tipo de documento : |
documento electrónico |
| Autores : |
Luis Vicente Syro Moreno, |
| Fecha de publicación : |
2011 |
| Títulos uniformes : |
Endocrine Pathology
|
| Idioma : |
Inglés (eng) |
| Palabras clave : |
Undifferentiated sarcoma sella turcica rhabdomyosarcoma immunohistochemistry |
| Resumen : |
Malignancies lacking specific features of cellular maturation are termed “undifferentiated” and represent 5–10% of all human tumors. They are encountered at a variety of sites but do not, as a rule, arise in the sellar region. A 39-year-old male with a history of testicular seminoma and an unsuccessful biopsy of a third ventricular neoplasm, presented with visual disturbances and memory loss. Light microscopically, the tumor consisted entirely of undifferentiated spindle cells. No germ cell component was noted. An exhaustive immunohistochemical study found immunoreactivity for vimentin and desmin, but for no other myoid markers. Polymerase chain reaction showed no X;18 translocation. Based upon these studies, a diagnosis of “undifferentiated sarcoma” was made. Our case, being highly unusual among reported sellar neoplasms, underscores the difficulties inherent in the differential diagnosis of undifferentiated neoplasms. |
| Mención de responsabilidad : |
Branavan Manoranjan, Luis V Syro, Bernd W Scheithauer, Leon D Ortiz, Eva Horvath, Fateme Salehi, Kalman Kovacs, Michael D Cusimano |
| Referencia : |
Endocr Pathol. 2011 Sep;22(3):159-64. |
| DOI (Digital Object Identifier) : |
10.1007/s12022-011-9166-7 |
| PMID : |
21681665 |
| En línea : |
https://link.springer.com/article/10.1007%2Fs12022-011-9166-7 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3566 |
Undifferentiated sarcoma of the sellar region [documento electrónico] / Luis Vicente Syro Moreno, . - 2011. Obra : Endocrine PathologyIdioma : Inglés ( eng) | Palabras clave : |
Undifferentiated sarcoma sella turcica rhabdomyosarcoma immunohistochemistry |
| Resumen : |
Malignancies lacking specific features of cellular maturation are termed “undifferentiated” and represent 5–10% of all human tumors. They are encountered at a variety of sites but do not, as a rule, arise in the sellar region. A 39-year-old male with a history of testicular seminoma and an unsuccessful biopsy of a third ventricular neoplasm, presented with visual disturbances and memory loss. Light microscopically, the tumor consisted entirely of undifferentiated spindle cells. No germ cell component was noted. An exhaustive immunohistochemical study found immunoreactivity for vimentin and desmin, but for no other myoid markers. Polymerase chain reaction showed no X;18 translocation. Based upon these studies, a diagnosis of “undifferentiated sarcoma” was made. Our case, being highly unusual among reported sellar neoplasms, underscores the difficulties inherent in the differential diagnosis of undifferentiated neoplasms. |
| Mención de responsabilidad : |
Branavan Manoranjan, Luis V Syro, Bernd W Scheithauer, Leon D Ortiz, Eva Horvath, Fateme Salehi, Kalman Kovacs, Michael D Cusimano |
| Referencia : |
Endocr Pathol. 2011 Sep;22(3):159-64. |
| DOI (Digital Object Identifier) : |
10.1007/s12022-011-9166-7 |
| PMID : |
21681665 |
| En línea : |
https://link.springer.com/article/10.1007%2Fs12022-011-9166-7 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3566 |
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Undifferentiated sarcoma of the sellar region
