| Título : |
Stool short-chain fatty acids in critically ill patients with sepsis |
| Tipo de documento : |
documento electrónico |
| Autores : |
Adriana Giraldo Villa, |
| Fecha de publicación : |
2020 |
| Títulos uniformes : |
Journal of the American College of Nutrition
|
| Idioma : |
Inglés (eng) |
| Palabras clave : |
Short-chain fatty acids critically ill patient sepsis acetic propionic butyric intensive care unit |
| Resumen : |
Objective: To determine the concentration of stool short-chain fatty acids (SCFAs) in critically ill patients with sepsis and to compare the results between the critically ill patient and the control group. Methods: This descriptive, multicenter, observational study was conducted in five health institutions. Over a 6-month study period, critically ill patients with sepsis who were admitted to the intensive care unit (ICU) and met the inclusion criteria were enrolled, and a control, paired by age and sex, was recruited for each patient. A spontaneous stool sample was collected from each participant and a gas chromatograph coupled to a mass spectrometer (Agilent 7890/MSD 5975 C) was used to measure the concentrations SCFAs. Results: The final sample included 44 patients and 45 controls. There were no differences in the age and sex distributions between the groups (p > 0.05). According to body mass index (BMI), undernutrition was more prevalent among critically ill patients, and BMI in control subjects was most frequently classified as overweight (p = 0.024). Propionic acid, acetic acid, butyric acid, and isobutyric acid concentrations were significantly lower in the critically ill patient group than in the control group (p = 0.000). No association with outcome variables (complications, ICU stay, and discharge condition) was found in the patients, and patients diagnosed with infection on ICU admission showed significant decreases in butyric and isobutyric acid concentrations with respect to other diagnostic criteria (p |
| Mención de responsabilidad : |
Beatriz E Valdés-Duque, Nubia A Giraldo-Giraldo, Ana M Jaillier-Ramírez, Adriana Giraldo-Villa, Irene Acevedo-Castaño, Mónica A Yepes-Molina, Janeth Barbosa-Barbosa, Carlos J Barrera-Causil, Gloria M Agudelo-Ochoa |
| Referencia : |
J Am Coll Nutr. Nov-Dec 2020;39(8):706-712. |
| DOI (Digital Object Identifier) : |
10.1080/07315724.2020.1727379 |
| PMID : |
32163012 |
| En línea : |
https://www.tandfonline.com/doi/full/10.1080/07315724.2020.1727379 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5084 |
Stool short-chain fatty acids in critically ill patients with sepsis [documento electrónico] / Adriana Giraldo Villa, . - 2020. Obra : Journal of the American College of NutritionIdioma : Inglés ( eng) | Palabras clave : |
Short-chain fatty acids critically ill patient sepsis acetic propionic butyric intensive care unit |
| Resumen : |
Objective: To determine the concentration of stool short-chain fatty acids (SCFAs) in critically ill patients with sepsis and to compare the results between the critically ill patient and the control group. Methods: This descriptive, multicenter, observational study was conducted in five health institutions. Over a 6-month study period, critically ill patients with sepsis who were admitted to the intensive care unit (ICU) and met the inclusion criteria were enrolled, and a control, paired by age and sex, was recruited for each patient. A spontaneous stool sample was collected from each participant and a gas chromatograph coupled to a mass spectrometer (Agilent 7890/MSD 5975 C) was used to measure the concentrations SCFAs. Results: The final sample included 44 patients and 45 controls. There were no differences in the age and sex distributions between the groups (p > 0.05). According to body mass index (BMI), undernutrition was more prevalent among critically ill patients, and BMI in control subjects was most frequently classified as overweight (p = 0.024). Propionic acid, acetic acid, butyric acid, and isobutyric acid concentrations were significantly lower in the critically ill patient group than in the control group (p = 0.000). No association with outcome variables (complications, ICU stay, and discharge condition) was found in the patients, and patients diagnosed with infection on ICU admission showed significant decreases in butyric and isobutyric acid concentrations with respect to other diagnostic criteria (p |
| Mención de responsabilidad : |
Beatriz E Valdés-Duque, Nubia A Giraldo-Giraldo, Ana M Jaillier-Ramírez, Adriana Giraldo-Villa, Irene Acevedo-Castaño, Mónica A Yepes-Molina, Janeth Barbosa-Barbosa, Carlos J Barrera-Causil, Gloria M Agudelo-Ochoa |
| Referencia : |
J Am Coll Nutr. Nov-Dec 2020;39(8):706-712. |
| DOI (Digital Object Identifier) : |
10.1080/07315724.2020.1727379 |
| PMID : |
32163012 |
| En línea : |
https://www.tandfonline.com/doi/full/10.1080/07315724.2020.1727379 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5084 |
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