Infectious endotheliitis : a rare case of presumed mycotic origin [documento electrónico] / Luis Fernando Zapata González, ; José David Paulo Trujillo, ; Carlos Alberto Restrepo Peláez,  . - 2013.
Obra : Clinical Ophthalmology

Idioma : Inglés (eng)

Palabras clave :	Endotheliitis  mycotic  keratitis  voriconazole
Resumen :	Purpose: To report an interesting case of infectious endotheliitis of presumed mycotic origin. Methods: A case report of a 56-year-old male farmer who sought medical attention after a month-long evolution of irritative symptoms in his right eye, accompanied by visual acuity (VA) impairment. The patient received topical and oral broad-spectrum antibiotic treatment with no improvement before being referred to a cornea specialist, where he was found to have VA of 20/150 and was noted on biomicroscopy to have endothelial feathery coalescent lesions. The patient was admitted to the hospital for an aqueous humor sample and intravenous voriconazole. Results: The microbiological studies did not isolate any micro-organisms. However, clinical evidence of improvement was confirmed after 5 days of antimycotic intravenous therapy. Complete clinical resolution was achieved at 1 month after treatment completion with oral voriconazole, as evidenced by VA of 20/20 and disappearance of endothelial lesions. Conclusion: Endothelial involvement by fungi is a rare condition. In this case, no microbes were isolated, but the characteristic morphology of the lesions, the history of onychomycosis, and the spectacular response to voriconazole turn this case into a valid presumptive diagnosis.
Mención de responsabilidad :	Luis Fernando Zapata, José David Paulo, Carlos A Restrepo, Luis Fernando Velásquez, Andrés E Toro Montoya, Melissa A Zapata
Referencia :	Clin Ophthalmol. 2013;7:1459-61.
DOI (Digital Object Identifier) :	10.2147/OPTH.S43695
PMID :	23901253
Derechos de uso :	CC BY-NC
En línea :	https://www.dovepress.com/infectious-endotheliitis-a-rare-case-of-presumed-mycot [...]
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