| Título : |
Autophagy in endocrine tumors |
| Tipo de documento : |
documento electrónico |
| Autores : |
Luis Vicente Syro Moreno, |
| Fecha de publicación : |
2015 |
| Títulos uniformes : |
Endocrine Related Cancer
|
| Idioma : |
Inglés (eng) |
| Palabras clave : |
Autophagy autophagy modulation endocrine disease neoplasia therapeutic potential |
| Resumen : |
Autophagy is an important intracellular process involving the degradation of cytoplasmic components. It is involved in both physiological and pathological conditions, including cancer. The role of autophagy in cancer is described as a ‘double-edged sword,’ a term that reflects its known participation in tumor suppression, tumor survival and tumor cell proliferation. Available research regarding autophagy in endocrine cancer supports this concept. Autophagy shows promise as a novel therapeutic target in different types of endocrine cancer, inhibiting or increasing treatment efficacy in a context- and cell-type dependent manner. At present, however, there is very little research concerning autophagy in endocrine tumors. No research was reported connecting autophagy to some of the tumors of the endocrine glands such as the pancreas and ovary. This review aims to elucidate the roles of autophagy in different types of endocrine cancer and highlight the need for increased research in the field. |
| Mención de responsabilidad : |
Andrea Weckman, Fabio Rotondo, Antonio Di Ieva, Luis V Syro, Henriett Butz, Michael D Cusimano and Kalman Kovacs |
| Referencia : |
Endoc Rel Cancer. 2015;22(4):205-18. |
| DOI (Digital Object Identifier) : |
10.1530/ERC-15-0042 |
| En línea : |
https://erc.bioscientifica.com/view/journals/erc/22/4/R205.xml |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3901 |
Autophagy in endocrine tumors [documento electrónico] / Luis Vicente Syro Moreno, . - 2015. Obra : Endocrine Related CancerIdioma : Inglés ( eng) | Palabras clave : |
Autophagy autophagy modulation endocrine disease neoplasia therapeutic potential |
| Resumen : |
Autophagy is an important intracellular process involving the degradation of cytoplasmic components. It is involved in both physiological and pathological conditions, including cancer. The role of autophagy in cancer is described as a ‘double-edged sword,’ a term that reflects its known participation in tumor suppression, tumor survival and tumor cell proliferation. Available research regarding autophagy in endocrine cancer supports this concept. Autophagy shows promise as a novel therapeutic target in different types of endocrine cancer, inhibiting or increasing treatment efficacy in a context- and cell-type dependent manner. At present, however, there is very little research concerning autophagy in endocrine tumors. No research was reported connecting autophagy to some of the tumors of the endocrine glands such as the pancreas and ovary. This review aims to elucidate the roles of autophagy in different types of endocrine cancer and highlight the need for increased research in the field. |
| Mención de responsabilidad : |
Andrea Weckman, Fabio Rotondo, Antonio Di Ieva, Luis V Syro, Henriett Butz, Michael D Cusimano and Kalman Kovacs |
| Referencia : |
Endoc Rel Cancer. 2015;22(4):205-18. |
| DOI (Digital Object Identifier) : |
10.1530/ERC-15-0042 |
| En línea : |
https://erc.bioscientifica.com/view/journals/erc/22/4/R205.xml |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3901 |
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Autophagy in endocrine tumors
