Sodium bicarbonate versus isotonic saline solution to prevent contrast-induced nephropathy: a systematic review and meta-analysis = El bicarbonato de sodio en comparación con solución salina isotónica para prevenir la nefropatí­a inducida por contraste: Una revisión sistemática y meta-análisis [documento electrónico] / Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Jorge Hernando Donado Gómez,  . - 2015.
Obra : Colombia Médica

Idioma : Inglés (eng)

Palabras clave :	Contrast induced nephropathy  acute kidney injury  sodium bicarbonate  sodium chloride
Resumen :	Introduction: Contrast-induced nephropathy is one of the main causes of acute kidney injury and increased hospital-acquired morbidity and mortality. The use of sodium bicarbonate for nephroprotection has emerged as a preventative strategy; however, its efficacy is controversial compared to other strategies, such as hydration using 0.9% saline solution. Objective: To compare the effectiveness of sodium bicarbonate vs. hydration using 0.9% saline solution to prevent contrast-induced acute kidney injury. Methods: A systematic review of studies registered in the COCHRANE, PUBMED, MEDLINE, LILACS, SCIELO and EMBASE databases was conducted. Randomized controlled studies that evaluated the use of 0.9% saline solution vs. sodium bicarbonate to prevent contrast-induced nephropathy were included. Results: A total of 22 studies (5,686 patients) were included. Sodium bicarbonate did not decrease the risk of contrast-induced nephropathy (RD= 0.00; 95% CI= -0.02 to 0.03; p= 0.83; I2= 0%). No significant differences were found in the demand for renal replacement therapy (RD= 0.00; 95% CI= -0.01 to 0-01; I2 = 0%; p= 0.99) or in mortality (RD= -0.00; 95% CI= -0.001 to 0.001; I2 = 0%; p= 0.51). Conclusions: Sodium bicarbonate administration is not superior to the use of 0.9% saline solution for preventing contrast-induced nephropathy in patients with risk factors, nor is it better at reducing mortality or the need for renal replacement therapy.
Mención de responsabilidad :	Carlos Andres Zapata-Chica, Diana Bello Marquez, Lina Maria Serna-Higuita, John Fredy Nieto-Ríos, Fabian David Casas-Arroyave, Jorge Hernando Donado-Gómez
Referencia :	Colomb Med (Cali). 2015 Sep 30;46(3):90-103.
DOI (Digital Object Identifier) :	10.25100/cm.v46i3.1925
PMID :	26600623
Derechos de uso :	CC BY
En línea :	https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1925
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3913