In vivo absolute quantification of carnosine in the vastus lateralis muscle with 1H MRS using a surface coil and water as internal reference / Vega, Gloria  

Público ISBD [Publicación periódica]  Título : In vivo absolute quantification of carnosine in the vastus lateralis muscle with 1H MRS using a surface coil and water as internal reference Tipo de documento : documento electrónico Autores : Vega, Gloria, Autor ; Ricaurte, German, Autor ; Mauricio Estrada Castrillón, Autor ; Reyngoudt, Harmen, Autor ; Cardona, Oscar M., Autor ; Gallo Villegas, Jaime A., Autor ; Narváez Sánchez, Raúl, Autor ; Calderón, Juan C., Autor Fecha de publicación : 2023 ISBN/ISSN/DL : 98700011900 Idioma : Inglés (eng) Materias : Carnosine Palabras clave : Carnosine  Proton magnetic resonance spectroscopy  Skeletal muscle  Vastus lateralis  Gastrocnemius Clasificación: AC-2023-001 Resumen : Phantom’s experiments showed a maximum error of 7%, highlighting the validity of the measurements in the study setup. The carnosine concentrations (mmol/kg ww, mean?±?SD) measured in the GM were 6.8?±?2.2 with the VC (CcarVC) and 10.2?±?3.0 with the SC (CcarSC) (P?=?0.013; n?=?9). Therefore, a correction was applied to these measurements (CcarVC?=?0.6582*CcarSC), to make coils performance comparable (6.8?±?2.2 for VC and 6.7?±?2.0 for SC, P?=?0.97). After that, only the SC was used to quantify carnosine in the VLM, where a concentration of 5.4?±?1.5 (n?=?30) was found, with significant differences between men (6.2?±?1.3; n?=?15) and women (4.6?±?1.2; n?=?15). The error in quantitation was 5.3–5.5% with both coils. Nota de contenido : To standardize a method for 1H MRS intramuscular absolute quantification of carnosine in the thigh, using a surface coil and water as internal reference. Derechos de uso : Permiso de republicación otorgado al HPTU En línea : https://link.springer.com/article/10.1007/s00256-022-04149-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6164 [Publicación periódica] In vivo absolute quantification of carnosine in the vastus lateralis muscle with 1H MRS using a surface coil and water as internal reference [documento electrónico] / Vega, Gloria, Autor ; Ricaurte, German, Autor ; Mauricio Estrada Castrillón, Autor ; Reyngoudt, Harmen, Autor ; Cardona, Oscar M., Autor ; Gallo Villegas, Jaime A., Autor ; Narváez Sánchez, Raúl, Autor ; Calderón, Juan C., Autor . - 2023. ISSN : 98700011900 Idioma : Inglés (eng) Materias : Carnosine Palabras clave : Carnosine  Proton magnetic resonance spectroscopy  Skeletal muscle  Vastus lateralis  Gastrocnemius Clasificación: AC-2023-001 Resumen : Phantom’s experiments showed a maximum error of 7%, highlighting the validity of the measurements in the study setup. The carnosine concentrations (mmol/kg ww, mean?±?SD) measured in the GM were 6.8?±?2.2 with the VC (CcarVC) and 10.2?±?3.0 with the SC (CcarSC) (P?=?0.013; n?=?9). Therefore, a correction was applied to these measurements (CcarVC?=?0.6582*CcarSC), to make coils performance comparable (6.8?±?2.2 for VC and 6.7?±?2.0 for SC, P?=?0.97). After that, only the SC was used to quantify carnosine in the VLM, where a concentration of 5.4?±?1.5 (n?=?30) was found, with significant differences between men (6.2?±?1.3; n?=?15) and women (4.6?±?1.2; n?=?15). The error in quantitation was 5.3–5.5% with both coils. Nota de contenido : To standardize a method for 1H MRS intramuscular absolute quantification of carnosine in the thigh, using a surface coil and water as internal reference. Derechos de uso : Permiso de republicación otorgado al HPTU En línea : https://link.springer.com/article/10.1007/s00256-022-04149-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6164

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