Pathology of GH-producing pituitary adenomas and GH cell hyperplasia of the pituitary [documento electrónico] / Luis Vicente Syro Moreno,  . - 2017.
Obra : Pituitary

Idioma : Inglés (eng)

Palabras clave :	Acromegaly  classification  diagnosis  immunohistochemistry  pathology  pituitary neoplasms
Resumen :	Introduction: Histologic, immunohistochemical and electron microscopic studies have provided conclusive evidence that a marked diversity exists between tumors which secrete growth hormone (GH) in excess. GH cell hyperplasia can also be associated with acromegaly in patients with extrapituitary GH—releasing hormone secreting tumors or in familial pituitary tumor syndromes. Materials and methods: A literature search was performed for information regarding pathology, GH-producing tumors and acromegaly. Results: This review summarizes the current knowledge on the morphology of GH-producing and silent GH adenomas, as well as GH hyperplasia of the pituitary. Conclusion: The importance of morphologic classification and identification of different subgroups of patients with GH-producing adenomas and their impact on clinical management is discussed.
Mención de responsabilidad :	Luis V Syro, Fabio Rotondo, Carlos A Serna, Leon D Ortiz, Kalman Kovacs
Referencia :	Pituitary. 2017 Feb;20(1):84-92.
DOI (Digital Object Identifier) :	10.1007/s11102-016-0748-8
PMID :	27586499
En línea :	https://link.springer.com/article/10.1007%2Fs11102-016-0748-8
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4088