| Título : |
Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data |
| Tipo de documento : |
documento electrónico |
| Autores : |
Parra Izquierdo, Viviana, Autor ; Otero Regino, William, Autor ; Fabián Juliao Baños, Autor ; Frías Ordoñez, Juan Sebastián, Autor ; Ibañez Pinilla, Edgar, Autor ; Gil Parada, Fabio Leonel, Autor ; Marulanda Fernández, Hernando, Autor ; Otero Parra, Lina, Autor ; Otero Ramos, Elder, Autor ; Puentes Manosalva, Fabian Eduardo, Autor ; Guzmán Rojas, Gerardo Andrés, Autor ; Ernest Suarez, Kenneth, Autor ; Villa Ovalles, Keyla, Autor ; Paredes Mendez, Juan Eloy, Autor ; Jara Alba, María Luisa, Autor ; Andrade Zamora, David, Autor ; Ardila Báez, Manuel Alonso, Autor ; Floréz Sarmiento, Cristian, Autor ; Veitia, Guillermo, Autor ; Sánchez, Abel, Autor ; Arango Molano, Lazaro Antonio, Autor ; Fluxa, Fernando, Autor ; Freitas Queiroz, Natália Sousa, Autor ; Serrano, Mariastella, Autor |
| Fecha de publicación : |
2025 |
| Títulos uniformes : |
Crohn's and Colitis 360
|
| Idioma : |
Inglés (eng) |
| Palabras clave : |
(MeSH): inflammatory bowel diseases; colitis; colonic neoplasms; colonoscopy; prognosis; ulcerative |
| Resumen : |
Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology. Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity. Surveillance colonoscopies were performed according to available technology. Risk factors for dysplasia detection were analyzed. Results: One hundred and forty-four patients, 55.5% women, mean age 47.3 (range 17.1 to 90; SD 15.64) years and mean duration of disease 12.71 (range 0.64 to 57.13; SD 8.08) years. Forty-nine lesions were identified, 18 corresponded to dysplasia. The detection rate of dysplasia per lesion and per procedure was 36.7% and 12.5%, respectively. By logistic regression analysis, the duration of disease (OR 1.12;95%CI:1.047 to 1.215, P = .002) and the presence of post-inflammatory polyps (OR 3.4;95%CI:1.11 to 10.36, P = .031) were risk factors for higher detection of dysplasia. Digital chromoendoscopy was associated with greater detection of dysplasia (OR 4.99, 95%CI: 1.092 to 22.864, P = .038). Conclusions: In our region, the duration of disease and the presence of post-inflammatory polyps were the factors with the highest association for dysplasia detection, and digital chromoendoscopy with directed biopsies was the technique of choice. The implementation of a specific surveillance program in colonoscopy in IBD is an effective strategy to achieve high detection rates. © 2025 The Author(s). |
| Mención de responsabilidad : |
Parra-Izquierdo, Viviana, Otero-Regino, William, Juliao-Baños, Fabian, Frías-Ordoñez, Juan Sebastián, Ibañez-Pinilla, Edgar, Gil-Parada, Fabio Leonel, Marulanda-Fernández, Hernando, Otero-Parra, Lina, Otero-Ramos, Elder, Puentes-Manosalva, Fabian Eduardo, Guzmán Rojas, Gerardo Andres, Ernest-Suárez, Kenneth, Villa-Ovalles, Keyla, Paredes-Mendez, Juan Eloy, Jara-Alba, María Luisa, Andrade-Zamora, David, Ardila-Báez, Manuel Alonso, Flórez-Sarmiento, Cristian, Veitia, Guillermo, Sánchez, Abel, Arango-Molano, Lazaro Antonio, Fluxa, Fernando, Freitas Queiroz, Natália Sousa, Serrano, Mariastella |
| Referencia : |
Crohns Colitis 360 . 2025 Jan 14;7(1):otae081 |
| DOI (Digital Object Identifier) : |
10.1093/crocol/otae081 |
| PMID : |
39834355 |
| Derechos de uso : |
CC BY-NC-ND |
| En línea : |
https://pubmed.ncbi.nlm.nih.gov/39834355/ |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data [documento electrónico] / Parra Izquierdo, Viviana, Autor ; Otero Regino, William, Autor ; Fabián Juliao Baños, Autor ; Frías Ordoñez, Juan Sebastián, Autor ; Ibañez Pinilla, Edgar, Autor ; Gil Parada, Fabio Leonel, Autor ; Marulanda Fernández, Hernando, Autor ; Otero Parra, Lina, Autor ; Otero Ramos, Elder, Autor ; Puentes Manosalva, Fabian Eduardo, Autor ; Guzmán Rojas, Gerardo Andrés, Autor ; Ernest Suarez, Kenneth, Autor ; Villa Ovalles, Keyla, Autor ; Paredes Mendez, Juan Eloy, Autor ; Jara Alba, María Luisa, Autor ; Andrade Zamora, David, Autor ; Ardila Báez, Manuel Alonso, Autor ; Floréz Sarmiento, Cristian, Autor ; Veitia, Guillermo, Autor ; Sánchez, Abel, Autor ; Arango Molano, Lazaro Antonio, Autor ; Fluxa, Fernando, Autor ; Freitas Queiroz, Natália Sousa, Autor ; Serrano, Mariastella, Autor . - 2025. Obra : Crohn's and Colitis 360Idioma : Inglés ( eng)
| Palabras clave : |
(MeSH): inflammatory bowel diseases; colitis; colonic neoplasms; colonoscopy; prognosis; ulcerative |
| Resumen : |
Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology. Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity. Surveillance colonoscopies were performed according to available technology. Risk factors for dysplasia detection were analyzed. Results: One hundred and forty-four patients, 55.5% women, mean age 47.3 (range 17.1 to 90; SD 15.64) years and mean duration of disease 12.71 (range 0.64 to 57.13; SD 8.08) years. Forty-nine lesions were identified, 18 corresponded to dysplasia. The detection rate of dysplasia per lesion and per procedure was 36.7% and 12.5%, respectively. By logistic regression analysis, the duration of disease (OR 1.12;95%CI:1.047 to 1.215, P = .002) and the presence of post-inflammatory polyps (OR 3.4;95%CI:1.11 to 10.36, P = .031) were risk factors for higher detection of dysplasia. Digital chromoendoscopy was associated with greater detection of dysplasia (OR 4.99, 95%CI: 1.092 to 22.864, P = .038). Conclusions: In our region, the duration of disease and the presence of post-inflammatory polyps were the factors with the highest association for dysplasia detection, and digital chromoendoscopy with directed biopsies was the technique of choice. The implementation of a specific surveillance program in colonoscopy in IBD is an effective strategy to achieve high detection rates. © 2025 The Author(s). |
| Mención de responsabilidad : |
Parra-Izquierdo, Viviana, Otero-Regino, William, Juliao-Baños, Fabian, Frías-Ordoñez, Juan Sebastián, Ibañez-Pinilla, Edgar, Gil-Parada, Fabio Leonel, Marulanda-Fernández, Hernando, Otero-Parra, Lina, Otero-Ramos, Elder, Puentes-Manosalva, Fabian Eduardo, Guzmán Rojas, Gerardo Andres, Ernest-Suárez, Kenneth, Villa-Ovalles, Keyla, Paredes-Mendez, Juan Eloy, Jara-Alba, María Luisa, Andrade-Zamora, David, Ardila-Báez, Manuel Alonso, Flórez-Sarmiento, Cristian, Veitia, Guillermo, Sánchez, Abel, Arango-Molano, Lazaro Antonio, Fluxa, Fernando, Freitas Queiroz, Natália Sousa, Serrano, Mariastella |
| Referencia : |
Crohns Colitis 360 . 2025 Jan 14;7(1):otae081 |
| DOI (Digital Object Identifier) : |
10.1093/crocol/otae081 |
| PMID : |
39834355 |
| Derechos de uso : |
CC BY-NC-ND |
| En línea : |
https://pubmed.ncbi.nlm.nih.gov/39834355/ |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
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Clasificado(s) por (Año de edición descendente) Refinar búsquedaDysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data / Parra Izquierdo, Viviana ; Otero Regino, William ; Fabián Juliao Baños ; Frías Ordoñez, Juan Sebastián ; Ibañez Pinilla, Edgar ; Gil Parada, Fabio Leonel ; Marulanda Fernández, Hernando ; Otero Parra, Lina ; Otero Ramos, Elder ; Puentes Manosalva, Fabian Eduardo ; Guzmán Rojas, Gerardo Andrés ; Ernest Suarez, Kenneth ; Villa Ovalles, Keyla ; Paredes Mendez, Juan Eloy ; Jara Alba, María Luisa ; Andrade Zamora, David ; Ardila Báez, Manuel Alonso ; Floréz Sarmiento, Cristian ; Veitia, Guillermo ; Sánchez, Abel ; Arango Molano, Lazaro Antonio ; Fluxa, Fernando ; Freitas Queiroz, Natália Sousa ; Serrano, Mariastella
