| Título : |
Primary Thrombotic Microangiopathy in Pediatric Patients |
| Tipo de documento : |
documento electrónico |
| Autores : |
Pamplona Sierra, Ana Paulina, Autor ; Martínez Sánchez, Lina María, Autor ; Vergara Yánez, Daniela, Autor ; Franco Hincapié, Liliana, Autor ; Baquero Rodríguez, Richard, Autor |
| Fecha de publicación : |
2024 |
| Títulos uniformes : |
Global Pediatric Health
|
| Idioma : |
Inglés (eng) |
| Palabras clave : |
purpura thrombocytopenic ADAMTS13 protein acute kidney injury hemolytic-uremic syndrome |
| Resumen : |
Background. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Methodology. A retrospective study that included patients younger than 18?years diagnosed with primary thrombotic microangiopathy between 2011 and 2021. Results. Thirty patients were included, of which 63% corresponded to a hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, and 30% to the atypical hemolytic uremic syndrome. The median age was 2.8?years and female sex predominated at 57%. On admission to the emergency room, fever and fatigue were the most frequent symptoms (93%), followed by oliguria and anuria (80%). 48% of patients received hemodialysis during their care. Mortality was estimated at 13%. Conclusion. This study constitutes the largest series of primary thrombotic microangiopathy in the pediatric population of Latin America, where the etiological and clinical behavior of this condition is described. |
| Mención de responsabilidad : |
Andrés David Aranzazu Ceballos, Ana Paulina Pamplona Sierra, Daniela Vergara Yánez, Liliana Franco Hincapié, Richard Baquero Rodriguez. |
| Referencia : |
Global Pediatric HealthVolume 11, 2024 |
| DOI (Digital Object Identifier) : |
10.1177/2333794X241307535 |
| Derechos de uso : |
CC BY-NC |
| En línea : |
https://journals.sagepub.com/doi/full/10.1177/2333794X241307535 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
Primary Thrombotic Microangiopathy in Pediatric Patients [documento electrónico] / Pamplona Sierra, Ana Paulina, Autor ; Martínez Sánchez, Lina María, Autor ; Vergara Yánez, Daniela, Autor ; Franco Hincapié, Liliana, Autor ; Baquero Rodríguez, Richard, Autor . - 2024. Obra : Global Pediatric HealthIdioma : Inglés ( eng)
| Palabras clave : |
purpura thrombocytopenic ADAMTS13 protein acute kidney injury hemolytic-uremic syndrome |
| Resumen : |
Background. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Methodology. A retrospective study that included patients younger than 18?years diagnosed with primary thrombotic microangiopathy between 2011 and 2021. Results. Thirty patients were included, of which 63% corresponded to a hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli, and 30% to the atypical hemolytic uremic syndrome. The median age was 2.8?years and female sex predominated at 57%. On admission to the emergency room, fever and fatigue were the most frequent symptoms (93%), followed by oliguria and anuria (80%). 48% of patients received hemodialysis during their care. Mortality was estimated at 13%. Conclusion. This study constitutes the largest series of primary thrombotic microangiopathy in the pediatric population of Latin America, where the etiological and clinical behavior of this condition is described. |
| Mención de responsabilidad : |
Andrés David Aranzazu Ceballos, Ana Paulina Pamplona Sierra, Daniela Vergara Yánez, Liliana Franco Hincapié, Richard Baquero Rodriguez. |
| Referencia : |
Global Pediatric HealthVolume 11, 2024 |
| DOI (Digital Object Identifier) : |
10.1177/2333794X241307535 |
| Derechos de uso : |
CC BY-NC |
| En línea : |
https://journals.sagepub.com/doi/full/10.1177/2333794X241307535 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
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