Importancia de la orientación diagnóstica en hemofilia A adquirida = Adequate diagnosis of acquired hemophilia A [documento electrónico] / Kenny Mauricio Gálvez Cárdenas,  . - 2019.
Obra : Revista Médica de Chile

Idioma : Español (spa)

Palabras clave :	Diagnosis  factor VIII  hemophilic A  hemorrhagic disorders
Resumen :	Acquired hemophilia A (AHA) is a rare and life-threatening autoimmune hemorrhagic disorder where autoantibodies are developed against factor VIII. An early diagnosis is challenging and mandatory: an immediate hemostatic control is required to reduce morbidity and mortality. Laboratory features of AHA are: presence of autoantibodies against factor VIII, prolonged activated partial thromboplastin time (with normal prothrombin time and thrombin time) and decreased factor VIII levels. In some cases, the results of laboratory tests may be incorrect due to errors in analysis, blood extraction or manipulation of samples; also worth of consideration are limitations in the measurement range and low sensitivity of the tests. This review highlights the importance of adequate screening in patients with suspected AHA to make an adequate diagnosis and reduce overall fatal outcomes.
Mención de responsabilidad :	Claudia Patricia Casas Patarroyo, Claudia Del Pilar Agudelo López, Kenny Galvez, Jimmy Lagos Ibarra, Susan Martínez Rojas, Linda Ibatá Bernal
Referencia :	Rev Med Chil. 2019 Mar;147(3):334-341.
DOI (Digital Object Identifier) :	10.4067/S0034-98872019000300334
PMID :	31344171
En línea :	http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/6816/4794
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4239