| Título : |
Colombian consensus on autosomal dominant polycystic kidney disease |
| Otros títulos : |
Consenso colombiano sobre la poliquistosis renal autosómica dominante |
| Tipo de documento : |
documento electrónico |
| Autores : |
John Mauricio Lopera Vargas, Autor ; Roncallo, Angelica, Autor ; Aguirre, Marcelo, Autor ; Conde Manotas, Juan Carlos, Autor ; Gallón Blandón, Paula Andrea, Autor ; López, José Gabriel, Autor ; Mantilla, Andrea, Autor ; Martínez, Theo, Autor ; Olivares, Orlando, Autor ; Restrepo Valencia, Cesar Augusto, Autor ; Wassermann, Alfredo Osvaldo, Autor ; Bermon, Anderson, Autor ; Barros, Luis, Autor |
| Fecha de publicación : |
2025 |
| Títulos uniformes : |
Revista Colombiana de Nefrología
|
| Idioma : |
Inglés (eng) Idioma original : Español (spa) |
| Palabras clave : |
Autosomal Dominant; Chronic; Cystic; hypertension; Kidney Diseases; Polycystic Kidney; Renal Disease; Renal Insufficiency; tolvaptan |
| Resumen : |
Autosomal dominant polycystic kidney disease (ADPKD) is the most common cause of inherited adult nephropathy and stage 5 chronic kidney disease of genetic origin, it is a heterogeneo-us disease with phenotypic variability in relation to progression. All measures aimed at slowing the progression of renal disease should be established. Purpose: To generate evidence-based recommendations for the diagnosis, follow-up and treatment of patients with ADPKD, defining patients with rapid disease progression, guide general and specific treatment with the agent tolvaptan, establish recommendations for access to renal replacement therapies including transplantation, through an expert consensus. Methodology: Based on the formulation of pragmatic research questions related to ADPKD, a search for evidence was conducted in Pubmed, Scopus and Ovid between January 2012 and July 2023. The articles were selected by means of a systematic review and through the modified Delphi consensus methodology. The Oxford scale was applied to quantify the level of evidence of the total selected scien-tific articles. All final recommendations were categorised by grade according to the NHS guidelines classification. Results: A total of 18 recommendations were formulated for the diagnosis, treatment and follow-up of ADPKD. A panel of 10 thematic experts, a methodological expert and 2 external reviewers actively participated in the elaboration of the consensus. Conclusions: The recommendations based on evidence and clinical expertise adapted to the Colombian context will allow standardised guidance at national and regional level, the diagnosis and treatment of patients with ADPKD and provide guidance on the use and application of tolvaptan. © 2025, Asociacion Colombiana de Nefrologia e Hipertension Arterial. All rights reserved. |
| Mención de responsabilidad : |
Roncallo Angelica, Aguirre Marcelo, Conde Manotas Juan Carlos, Gallón Blandón Paula Andrea, Lopera Mauricio, López José Gabriel, Mantilla Andrea, Martínez Theo, Olivares Orlando, Restrepo-Valencia Cesar Augusto, Wassermann Alfredo Osvaldo, Bermon Anderson, Barros Luis. |
| Referencia : |
Colomb. Nefrol. [Internet]. 11 de febrero de 2025 [citado 28 de abril de 2025];12(1). |
| DOI (Digital Object Identifier) : |
10.22265/acnef.12.1.801 |
| Derechos de uso : |
CC BY-NC-ND |
| En línea : |
https://revistanefrologia.org/index.php/rcn/article/view/801 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
Colombian consensus on autosomal dominant polycystic kidney disease = Consenso colombiano sobre la poliquistosis renal autosómica dominante [documento electrónico] / John Mauricio Lopera Vargas, Autor ; Roncallo, Angelica, Autor ; Aguirre, Marcelo, Autor ; Conde Manotas, Juan Carlos, Autor ; Gallón Blandón, Paula Andrea, Autor ; López, José Gabriel, Autor ; Mantilla, Andrea, Autor ; Martínez, Theo, Autor ; Olivares, Orlando, Autor ; Restrepo Valencia, Cesar Augusto, Autor ; Wassermann, Alfredo Osvaldo, Autor ; Bermon, Anderson, Autor ; Barros, Luis, Autor . - 2025. Obra : Revista Colombiana de NefrologíaIdioma : Inglés ( eng) Idioma original : Español ( spa)
| Palabras clave : |
Autosomal Dominant; Chronic; Cystic; hypertension; Kidney Diseases; Polycystic Kidney; Renal Disease; Renal Insufficiency; tolvaptan |
| Resumen : |
Autosomal dominant polycystic kidney disease (ADPKD) is the most common cause of inherited adult nephropathy and stage 5 chronic kidney disease of genetic origin, it is a heterogeneo-us disease with phenotypic variability in relation to progression. All measures aimed at slowing the progression of renal disease should be established. Purpose: To generate evidence-based recommendations for the diagnosis, follow-up and treatment of patients with ADPKD, defining patients with rapid disease progression, guide general and specific treatment with the agent tolvaptan, establish recommendations for access to renal replacement therapies including transplantation, through an expert consensus. Methodology: Based on the formulation of pragmatic research questions related to ADPKD, a search for evidence was conducted in Pubmed, Scopus and Ovid between January 2012 and July 2023. The articles were selected by means of a systematic review and through the modified Delphi consensus methodology. The Oxford scale was applied to quantify the level of evidence of the total selected scien-tific articles. All final recommendations were categorised by grade according to the NHS guidelines classification. Results: A total of 18 recommendations were formulated for the diagnosis, treatment and follow-up of ADPKD. A panel of 10 thematic experts, a methodological expert and 2 external reviewers actively participated in the elaboration of the consensus. Conclusions: The recommendations based on evidence and clinical expertise adapted to the Colombian context will allow standardised guidance at national and regional level, the diagnosis and treatment of patients with ADPKD and provide guidance on the use and application of tolvaptan. © 2025, Asociacion Colombiana de Nefrologia e Hipertension Arterial. All rights reserved. |
| Mención de responsabilidad : |
Roncallo Angelica, Aguirre Marcelo, Conde Manotas Juan Carlos, Gallón Blandón Paula Andrea, Lopera Mauricio, López José Gabriel, Mantilla Andrea, Martínez Theo, Olivares Orlando, Restrepo-Valencia Cesar Augusto, Wassermann Alfredo Osvaldo, Bermon Anderson, Barros Luis. |
| Referencia : |
Colomb. Nefrol. [Internet]. 11 de febrero de 2025 [citado 28 de abril de 2025];12(1). |
| DOI (Digital Object Identifier) : |
10.22265/acnef.12.1.801 |
| Derechos de uso : |
CC BY-NC-ND |
| En línea : |
https://revistanefrologia.org/index.php/rcn/article/view/801 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
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Clasificado(s) por (Año de edición descendente) Refinar búsquedaColombian consensus on autosomal dominant polycystic kidney disease / John Mauricio Lopera Vargas ; Roncallo, Angelica ; Aguirre, Marcelo ; Conde Manotas, Juan Carlos ; Gallón Blandón, Paula Andrea ; López, José Gabriel ; Mantilla, Andrea ; Martínez, Theo ; Olivares, Orlando ; Restrepo Valencia, Cesar Augusto ; Wassermann, Alfredo Osvaldo ; Bermon, Anderson ; Barros, Luis
