Título : |
In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides |
Tipo de documento : |
documento electrónico |
Autores : |
Ángela Restrepo Moreno, ; María D. Arango, |
Fecha de publicación : |
1980 |
Títulos uniformes : |
Antimicrobial Agents and Chemotherapy
|
Idioma : |
Inglés (eng) |
Resumen : |
A total of 60 clinical isolates of Paracoccidioides brasiliensis were tested for susceptibility to sulfadiazine and sulfadimethoxyne by the agar dilution technique. A modification of the Mueller-Hinton medium was devised which gave good growth of the yeast form. The minimum inhibitory concentrations for only 51.6% of the isolates were in the range of the recommended blood serum concentration (50 micrograms/ml). For 6 to 8% of the isolates, the minimum inhibitory concentrations were above 200 micrograms of both sulfadiazine and sulfadimethoxyne per ml. A significant decreases in susceptibility was demonstrated for one isolate obtained from a patient relapsing during sulfonamide therapy. |
Mención de responsabilidad : |
A Restrepo, M D Arango |
Referencia : |
Antimicrob Agents Chemother. 1980 Jul;18(1):190-4. |
DOI (Digital Object Identifier) : |
10.1128/AAC.18.1.190 |
PMID : |
7416744 |
En línea : |
https://aac.asm.org/content/18/1/190 |
Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4317 |