| Título : |
In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides |
| Tipo de documento : |
documento electrónico |
| Autores : |
Ángela Restrepo Moreno, ; María D. Arango, |
| Fecha de publicación : |
1980 |
| Títulos uniformes : |
Antimicrobial Agents and Chemotherapy
|
| Idioma : |
Inglés (eng) |
| Resumen : |
A total of 60 clinical isolates of Paracoccidioides brasiliensis were tested for susceptibility to sulfadiazine and sulfadimethoxyne by the agar dilution technique. A modification of the Mueller-Hinton medium was devised which gave good growth of the yeast form. The minimum inhibitory concentrations for only 51.6% of the isolates were in the range of the recommended blood serum concentration (50 micrograms/ml). For 6 to 8% of the isolates, the minimum inhibitory concentrations were above 200 micrograms of both sulfadiazine and sulfadimethoxyne per ml. A significant decreases in susceptibility was demonstrated for one isolate obtained from a patient relapsing during sulfonamide therapy. |
| Mención de responsabilidad : |
A Restrepo, M D Arango |
| Referencia : |
Antimicrob Agents Chemother. 1980 Jul;18(1):190-4. |
| DOI (Digital Object Identifier) : |
10.1128/AAC.18.1.190 |
| PMID : |
7416744 |
| En línea : |
https://aac.asm.org/content/18/1/190 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
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In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides
