Ketoconazole in Paracoccidioidomycosis: Efficacy of prolonged oral therapy [documento electrónico] / Ángela Restrepo Moreno, ; Gloria Isabel Mejía de Rodríguez, ; Iván Gómez,  . - 1980.
Obra : Mycopathologia

Idioma : Inglés (eng)

Resumen :	Ketoconazole, a new oral imidazole derivative, was employed for the treatment of five patients with paracoccidioidomycosis. The response was excellent, with objective clinical improvement and healing of both mucocutaneous and pulmonary lesions. Mycological and serological tests, as well as delayed hypersensitivity, were assessed and found to correlate with clinical improvement. Therapy was conducted for 12 months with a dose of 200 mg day in 2 patients; in the remainder the dose was reduced (100 mg day) after the first 6 months and maintained as such for an equal period. No side-effects or toxicity were noted despite prolonged treatment. The advantages of the new therapeutic approach are discussed.
Mención de responsabilidad :	A. Restrepo, D. A. Stevens, E. Leiderman, J. Fuentes, A. Arana, R. Angel, G. Mejía & I. Gómez
Referencia :	Mycopathologia. 1980 Aug 29;72(1):35-45.
DOI (Digital Object Identifier) :	10.1007/BF00443049
PMID :	6252468
En línea :	https://link.springer.com/article/10.1007%2FBF00443049
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4319