An evaluation of the enzyme-linked immunoabsorbent assay (ELISA) for quantitation of antibodies to paracoccidioides brasiliensis [documento electrónico] / Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno,  . - 1986.
Obra : Journal of Medical and Veterinary Mycology

Idioma : Inglés (eng)

Resumen :	The ELISA procedure was adapted for quantitation of antibodies against Paracoccidioides brasiliensis. Using a yeast cytoplasmic antigen and sera from patients with proven paracoccidioidomycosis, we found that 66% of sera reacted at titers ≥1:128. Titers of this magnitude were obtained only for 4–5% of sera from healthy blood donors, tuberculosis patients and patients with other systemic mycoses. The exception was sera from patients with histoplasmosis (36% had titers ≥1:128). Follow-up of 10 paracoccidioidomycosis patients during the course of therapy indicated a gradual decrease in antibody titers. Because of the technical advantages of the ELISA procedure in comparison with the standard complement fixation test, the ELISA test has potential utility for the quantitative determination of antibodies in patients with paracoccidioidomycosis.
Mención de responsabilidad :	Luz E. Cano, Elmer Brummer, David A. Stevens, Angela Restrepo
Referencia :	J Med Vet Mycol. 1986 Dec;24(6):467-75.
DOI (Digital Object Identifier) :	10.1080/02681218680000741
PMID :	3572681
En línea :	https://academic.oup.com/mmy/article-abstract/24/6/467/875557
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4342