In vitro evaluation of lomefloxacin activity in Colombia [documento electrónico] / Hugo Trujillo Soto, ; Gloria Isabel Mejía de Rodríguez, ; Lucero Castrillón de P., ; C. Gómez,  . - 1989.
Obra : Diagnostic Microbiology and Infectious Disease

Idioma : Inglés (eng)

Resumen :	As part of the worldwide in vitro program to determine the antimicrobial activity of lomefloxacin, our study tested susceptibility of bacterial isolates from hospitals in Medellin, Colombia. A total of 504 bacterial isolates were obtained from patients at three different centers. For Enterobacteriaceae, 0.5 μg/ml inhibited 100% of the indole-positive Proteus and Salmonella spp.; 1 μg/ml inhibited 100% of Shigella and Citrobacter, 2 μg/ml inhibited 100% of Enterobacter spp., E. coli, Proteus mirabilis, and Serratia marcescens isolates tested. The MIC90 for Klebsiella spp. and Pseudomonas spp. was 4 μg/ml. The MIC90 was 4 μg/ml for S. aureus and 2 μg/ml for S. epidemidis and S. saprophyticus. The MIC90 of Streptococcus spp. were ⩽4 μg/ml for all isolates tested. Considering that 97.8% were susceptible to concentrations of ⩽4 μg/ml of lomefloxacin, this new quinolone offers potential in the therapy of a variety of systemic infections, especially in patients with multiply resistant pathogens.
Mención de responsabilidad :	H Trujillo, G I Mejia, L Castrillon, C Gomez
Referencia :	Diagn Microbiol Infect Dis. 1989 May-Jun;12(3 Suppl):51S-52S
DOI (Digital Object Identifier) :	10.1016/0732-8893(89)90066-7
PMID :	2791498
En línea :	https://linkinghub.elsevier.com/retrieve/pii/0732889389900667
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4352