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Autor Nieto, José Manuel
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Documentos disponibles escritos por este autor (2)
Clasificado(s) por (Año de edición descendente) Refinar búsquedaPhenotypic Variation in Disease Severity Among Hospitalized Pediatric Patients With COVID-19: Assessing the Impact of COVID-19 in the EPICO Study / Alejandro Díaz Díaz ; Sossa Alarcón, María Camila ; Gutiérrez, Mónica Paola ; Becerra, Natalia ; Ortegon, Luz Yessenia ; David, María Camila ; Naranjo Vanegas, Melisa ; Friedrich, Gabriela ; Vásquez Hoyos, Pablo ; Mesa Rubio, María Lucía ; Navarro Ramirez, Luis Miguel ; Moreno Lopez, Sergio ; Baquero, Olga Lucía ; Marina Mejía, Luz ; Piñeros, Juan Gabriel ; Restrepo Gualteros, Sonia ; Álvarez Moreno, Carlos ; Gutierrez Tobar, Iván ; Camilo Mesa, Andrés ; Bachiller Tuta, William Ricardo ; Galvis Diaz, Clara Esperanza ; Africano, Martha ; Nieto, José Manuel ; Pérez Camacho, Paola Marsela ; Beltrán Arroyave, Claudia ; Vivas Trochez, Rosalba ; Gastesi, Irati ; Moraleda, Cinta ; Tagarro García, Alfredo ; Herrero, Blanca ; Calleja, Lourdes ; Grasa, Carlos ; Rodriguez, Paula ; Melendo, Susana ; Soriano Arandes, Antoni ; Gómez Pastrana, Irene ; García García, Sonsoles ; Fumado, Victoria ; Ramirez Varela, Andrea
Título : Phenotypic Variation in Disease Severity Among Hospitalized Pediatric Patients With COVID-19: Assessing the Impact of COVID-19 in the EPICO Study Tipo de documento : documento electrónico Autores : Alejandro Díaz Díaz, Autor ; Sossa Alarcón, María Camila, Autor ; Gutiérrez, Mónica Paola, Autor ; Becerra, Natalia, Autor ; Ortegon, Luz Yessenia, Autor ; David, María Camila, Autor ; Naranjo Vanegas, Melisa, Autor ; Friedrich, Gabriela, Autor ; Vásquez Hoyos, Pablo, Autor ; Mesa Rubio, María Lucía, Autor ; Navarro Ramirez, Luis Miguel, Autor ; Moreno Lopez, Sergio, Autor ; Baquero, Olga Lucía, Autor ; Marina Mejía, Luz, Autor ; Piñeros, Juan Gabriel, Autor ; Restrepo Gualteros, Sonia, Autor ; Álvarez Moreno, Carlos, Autor ; Gutierrez Tobar, Iván, Autor ; Camilo Mesa, Andrés, Autor ; Bachiller Tuta, William Ricardo, Autor ; Galvis Diaz, Clara Esperanza, Autor ; Africano, Martha, Autor ; Nieto, José Manuel, Autor ; Pérez Camacho, Paola Marsela, Autor ; Beltrán Arroyave, Claudia, Autor ; Vivas Trochez, Rosalba, Autor ; Gastesi, Irati, Autor ; Moraleda, Cinta, Autor ; Tagarro García, Alfredo, Autor ; Herrero, Blanca, Autor ; Calleja, Lourdes, Autor ; Grasa, Carlos, Autor ; Rodriguez, Paula, Autor ; Melendo, Susana, Autor ; Soriano Arandes, Antoni, Autor ; Gómez Pastrana, Irene, Autor ; García García, Sonsoles, Autor ; Fumado, Victoria, Autor ; Ramirez Varela, Andrea, Autor Fecha de publicación : 2025 Títulos uniformes : International Journal of Collaborative Research on Internal Medicine & Public Health Idioma : Inglés (eng) Palabras clave : COVID-19 pediatrics inpatients cluster analysis SARS-CoV-2 variants Resumen : Objective To characterize the clinical phenotypes of SARS-CoV-2 infection in hospitalized children as part of the EPICO multicenter cohort study. Methods We included hospitalized children with confirmed SARS-CoV-2 infection from Colombian and Spanish institutions to assess disease evolution and outcomes. Cluster analysis was performed to identify clinical phenotypes. Results A total of 2318 patients were included (55% male, 36% infants). Five phenotype clusters emerged: Cluster 1 (26.5%): infants without comorbidities, low PICU admissions and mortality; Cluster 2 (18.5%): respiratory comorbidities, high microorganism co-detection and mortality; Cluster 3 (11.5%): fever, gastrointestinal symptoms, high PICU admissions; Cluster 4 (32%): mild unspecific symptoms, low mortality; Cluster 5 (11.3%): adolescents without comorbidities, low co-detection and hospitalization rates. Findings were consistent across both countries. Conclusion Identifying clinical phenotypes of SARS-CoV-2 in children may improve risk stratification and guide future management strategies. Mención de responsabilidad : María Camila Sossa-Alarcón1*†, Mónica Paola Gutiérrez1†, Natalia Becerra1†,Luz Yessenia Ortegon1†, María Camila David1†,Melisa Naranjo vanegas2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24, Gabriela Friedrich 2,Pablo Vásquez-Hoyos3, María Lucía Mesa-Rubio1,Luis Miguel Navarro-Ramirez2Sergio Moreno-Lopez2, Olga Lucía Baquero4, Luz Marina Mejía5, Juan Gabriel Piñeros1,Sonia Restrepo-Gualteros1, Carlos Álvarez-Moreno6, Alejandro Díaz-Díaz7, Iván Gutierrez-Tobar8, Andrés Camilo Mesa9, William Ricardo Bachiller Tuta10,Clara Esperanza Galvis Diaz11, Martha Africano12, José Manuel Nieto13,Paola Marcela Pérez Camacho14, Claudia Beltrán-Arroyave15, Rosalba Vivas Trochez16,Irati Gastesi17, Cinta Moraleda17, Alfredo Tagarro García17,18, Blanca Herrero19,Lourdes Calleja19, Carlos Grasa20, Paula Rodriguez20, Susana Melendo21,Antoni Soriano-Arandes21, Irene Gómez Pastrana17, Sonsoles García García17,Victoria Fumado22 and Andrea Ramírez Varela23 on behalf of EPICO-Colombia and EPICO-AEP Referencia : Int J Public Health. 2025 Mar 18;70:1607246 DOI (Digital Object Identifier) : 10.3389/ijph.2025.1607246 PMID : 40170693 Derechos de uso : CC BY-NC-ND En línea : https://pmc.ncbi.nlm.nih.gov/articles/PMC11959304/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Phenotypic Variation in Disease Severity Among Hospitalized Pediatric Patients With COVID-19: Assessing the Impact of COVID-19 in the EPICO Study [documento electrónico] / Alejandro Díaz Díaz, Autor ; Sossa Alarcón, María Camila, Autor ; Gutiérrez, Mónica Paola, Autor ; Becerra, Natalia, Autor ; Ortegon, Luz Yessenia, Autor ; David, María Camila, Autor ; Naranjo Vanegas, Melisa, Autor ; Friedrich, Gabriela, Autor ; Vásquez Hoyos, Pablo, Autor ; Mesa Rubio, María Lucía, Autor ; Navarro Ramirez, Luis Miguel, Autor ; Moreno Lopez, Sergio, Autor ; Baquero, Olga Lucía, Autor ; Marina Mejía, Luz, Autor ; Piñeros, Juan Gabriel, Autor ; Restrepo Gualteros, Sonia, Autor ; Álvarez Moreno, Carlos, Autor ; Gutierrez Tobar, Iván, Autor ; Camilo Mesa, Andrés, Autor ; Bachiller Tuta, William Ricardo, Autor ; Galvis Diaz, Clara Esperanza, Autor ; Africano, Martha, Autor ; Nieto, José Manuel, Autor ; Pérez Camacho, Paola Marsela, Autor ; Beltrán Arroyave, Claudia, Autor ; Vivas Trochez, Rosalba, Autor ; Gastesi, Irati, Autor ; Moraleda, Cinta, Autor ; Tagarro García, Alfredo, Autor ; Herrero, Blanca, Autor ; Calleja, Lourdes, Autor ; Grasa, Carlos, Autor ; Rodriguez, Paula, Autor ; Melendo, Susana, Autor ; Soriano Arandes, Antoni, Autor ; Gómez Pastrana, Irene, Autor ; García García, Sonsoles, Autor ; Fumado, Victoria, Autor ; Ramirez Varela, Andrea, Autor . - 2025.
Obra : International Journal of Collaborative Research on Internal Medicine & Public Health
Idioma : Inglés (eng)
Palabras clave : COVID-19 pediatrics inpatients cluster analysis SARS-CoV-2 variants Resumen : Objective To characterize the clinical phenotypes of SARS-CoV-2 infection in hospitalized children as part of the EPICO multicenter cohort study. Methods We included hospitalized children with confirmed SARS-CoV-2 infection from Colombian and Spanish institutions to assess disease evolution and outcomes. Cluster analysis was performed to identify clinical phenotypes. Results A total of 2318 patients were included (55% male, 36% infants). Five phenotype clusters emerged: Cluster 1 (26.5%): infants without comorbidities, low PICU admissions and mortality; Cluster 2 (18.5%): respiratory comorbidities, high microorganism co-detection and mortality; Cluster 3 (11.5%): fever, gastrointestinal symptoms, high PICU admissions; Cluster 4 (32%): mild unspecific symptoms, low mortality; Cluster 5 (11.3%): adolescents without comorbidities, low co-detection and hospitalization rates. Findings were consistent across both countries. Conclusion Identifying clinical phenotypes of SARS-CoV-2 in children may improve risk stratification and guide future management strategies. Mención de responsabilidad : María Camila Sossa-Alarcón1*†, Mónica Paola Gutiérrez1†, Natalia Becerra1†,Luz Yessenia Ortegon1†, María Camila David1†,Melisa Naranjo vanegas2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24, Gabriela Friedrich 2,Pablo Vásquez-Hoyos3, María Lucía Mesa-Rubio1,Luis Miguel Navarro-Ramirez2Sergio Moreno-Lopez2, Olga Lucía Baquero4, Luz Marina Mejía5, Juan Gabriel Piñeros1,Sonia Restrepo-Gualteros1, Carlos Álvarez-Moreno6, Alejandro Díaz-Díaz7, Iván Gutierrez-Tobar8, Andrés Camilo Mesa9, William Ricardo Bachiller Tuta10,Clara Esperanza Galvis Diaz11, Martha Africano12, José Manuel Nieto13,Paola Marcela Pérez Camacho14, Claudia Beltrán-Arroyave15, Rosalba Vivas Trochez16,Irati Gastesi17, Cinta Moraleda17, Alfredo Tagarro García17,18, Blanca Herrero19,Lourdes Calleja19, Carlos Grasa20, Paula Rodriguez20, Susana Melendo21,Antoni Soriano-Arandes21, Irene Gómez Pastrana17, Sonsoles García García17,Victoria Fumado22 and Andrea Ramírez Varela23 on behalf of EPICO-Colombia and EPICO-AEP Referencia : Int J Public Health. 2025 Mar 18;70:1607246 DOI (Digital Object Identifier) : 10.3389/ijph.2025.1607246 PMID : 40170693 Derechos de uso : CC BY-NC-ND En línea : https://pmc.ncbi.nlm.nih.gov/articles/PMC11959304/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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Título : What to Look for in Chest X?Rays of Pediatric Patients With COVID?19: Insights From a Colombian Cohort Tipo de documento : documento electrónico Autores : Alejandro Díaz Díaz, Autor ; Burgos, Claudia, Autor ; Mendez, Laura Melissa, Autor ; Rodriguez, María Margarita, Autor ; Martinez, Arianna, Autor ; Sanchez, Paola, Autor ; Tovar, Carolina, Autor ; Naranjo Vanegas, Melisa, Autor ; Friedrich, Gabriela, Autor ; Vásquez Hoyos, Pablo, Autor ; Mesa Rubio, María Lucía, Autor ; Triana Rodriguez, Gustavo Adolfo, Autor ; Royero Arias, Mónica, Autor ; Echeverry, Jessica, Autor ; Gamo, Tamara, Autor ; Moreno, Luz Ángela, Autor ; Baquero, Olga Lucía, Autor ; Marina Mejía, Luz, Autor ; Restrepo Gualteros, Sonia, Autor ; Navarro Ramirez, Luis Miguel, Autor ; Moreno Lopez, Sergio, Autor ; Piñeros, Juan Gabriel, Autor ; Álvarez Moreno, Carlos, Autor ; Gutierrez, Iván Felipe, Autor ; Galvis Diaz, Clara, Autor ; Nieto, José Manuel, Autor ; Gastesi, Irati, Autor ; Moraleda, Cinta, Autor ; Tagarro García, Alfredo, Autor ; Ramirez Varela, Andrea, Autor Fecha de publicación : 2025 Títulos uniformes : Pediatric Pulmonology Idioma : Inglés (eng) Palabras clave : COVID?19 | diagnostic imaging | EPICO study | intensive care unit | pediatric infection | radiology | SARS?CoV?2 Resumen : Despite advancements in vaccination and the transition from pandemic to endemic, SARS-CoV-2 continues to pose a medical challenge, particularly among children. In this context, imaging diagnostics, such as chest x-rays, are crucial to the initial treatment of patients. This study aims to characterize the radiological findings in pediatric patients with confirmed SARS-CoV-2 infection in Colombia between April 2020 and November 2021, as well as describe the clinical presentation, including those admission to intensive care. Methods: In Colombia, a multicenter cohort comprised patients aged 29 days to 17 years with confirmed SARS-CoV-2 infection and chest X-ray taken within 72 h of hospitalization. In two separate groups, four radiologists evaluated the images. A fifth radiologist reviewed all the X-rays; and subsequently, these readings were used to calculate the kappa coefficient and to solve discrepancies among the other radiologists. The results were compared from admission to intensive care. Results: Analysis was conducted on 392 patients with a median age of 2 years, the majority of whom (42%) were infants. Sixty-eight percent of the radiographs had normal results. Peribronchial thickening and interstitial opacity were the most common aberrant findings (59%), followed by alveolar opacity (12%). 88 percent of findings were bilateral. In our cohort, peribronchial thickening was the most common radiological pattern found in patients admitted the PICU and with ventilatory failure. Interobserver agreement was low for peribronchial thickening (kappa = 0.1), but higher for consolidations and alveolar opacities (kappa = 0.4 and 0.5, respectively). Conclusion: In pediatric patients with SARS-CoV-2, radiological findings are nonspecific and interobserver agreement is minimal. Although consolidation and alveolar opacities demonstrated greater concordance, they did not appear to reflect the clinical presentation; therefore, our results can suggest chest radiography is not considered useful for determining the severity of COVID-19 in Mención de responsabilidad : Claudia Burgos, Laura Melissa Mendez, María Margarita Rodriguez, Arianna Martinez, Paola Sanchez, Carolina Tovar, Melisa Naranjo Vanegas, Gabriela Friedrich, Pablo Vásquez Hoyos, María Lucía Mesa Rubio, Referencia : Pediatr Pulmonol . 2025 Mar;60(3):e27495. doi: 10.1002/ppul.27495. DOI (Digital Object Identifier) : 10.1002/ppul.27495 PMID : 40018994 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40018994/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis What to Look for in Chest X?Rays of Pediatric Patients With COVID?19: Insights From a Colombian Cohort [documento electrónico] / Alejandro Díaz Díaz, Autor ; Burgos, Claudia, Autor ; Mendez, Laura Melissa, Autor ; Rodriguez, María Margarita, Autor ; Martinez, Arianna, Autor ; Sanchez, Paola, Autor ; Tovar, Carolina, Autor ; Naranjo Vanegas, Melisa, Autor ; Friedrich, Gabriela, Autor ; Vásquez Hoyos, Pablo, Autor ; Mesa Rubio, María Lucía, Autor ; Triana Rodriguez, Gustavo Adolfo, Autor ; Royero Arias, Mónica, Autor ; Echeverry, Jessica, Autor ; Gamo, Tamara, Autor ; Moreno, Luz Ángela, Autor ; Baquero, Olga Lucía, Autor ; Marina Mejía, Luz, Autor ; Restrepo Gualteros, Sonia, Autor ; Navarro Ramirez, Luis Miguel, Autor ; Moreno Lopez, Sergio, Autor ; Piñeros, Juan Gabriel, Autor ; Álvarez Moreno, Carlos, Autor ; Gutierrez, Iván Felipe, Autor ; Galvis Diaz, Clara, Autor ; Nieto, José Manuel, Autor ; Gastesi, Irati, Autor ; Moraleda, Cinta, Autor ; Tagarro García, Alfredo, Autor ; Ramirez Varela, Andrea, Autor . - 2025.
Obra : Pediatric Pulmonology
Idioma : Inglés (eng)
Palabras clave : COVID?19 | diagnostic imaging | EPICO study | intensive care unit | pediatric infection | radiology | SARS?CoV?2 Resumen : Despite advancements in vaccination and the transition from pandemic to endemic, SARS-CoV-2 continues to pose a medical challenge, particularly among children. In this context, imaging diagnostics, such as chest x-rays, are crucial to the initial treatment of patients. This study aims to characterize the radiological findings in pediatric patients with confirmed SARS-CoV-2 infection in Colombia between April 2020 and November 2021, as well as describe the clinical presentation, including those admission to intensive care. Methods: In Colombia, a multicenter cohort comprised patients aged 29 days to 17 years with confirmed SARS-CoV-2 infection and chest X-ray taken within 72 h of hospitalization. In two separate groups, four radiologists evaluated the images. A fifth radiologist reviewed all the X-rays; and subsequently, these readings were used to calculate the kappa coefficient and to solve discrepancies among the other radiologists. The results were compared from admission to intensive care. Results: Analysis was conducted on 392 patients with a median age of 2 years, the majority of whom (42%) were infants. Sixty-eight percent of the radiographs had normal results. Peribronchial thickening and interstitial opacity were the most common aberrant findings (59%), followed by alveolar opacity (12%). 88 percent of findings were bilateral. In our cohort, peribronchial thickening was the most common radiological pattern found in patients admitted the PICU and with ventilatory failure. Interobserver agreement was low for peribronchial thickening (kappa = 0.1), but higher for consolidations and alveolar opacities (kappa = 0.4 and 0.5, respectively). Conclusion: In pediatric patients with SARS-CoV-2, radiological findings are nonspecific and interobserver agreement is minimal. Although consolidation and alveolar opacities demonstrated greater concordance, they did not appear to reflect the clinical presentation; therefore, our results can suggest chest radiography is not considered useful for determining the severity of COVID-19 in Mención de responsabilidad : Claudia Burgos, Laura Melissa Mendez, María Margarita Rodriguez, Arianna Martinez, Paola Sanchez, Carolina Tovar, Melisa Naranjo Vanegas, Gabriela Friedrich, Pablo Vásquez Hoyos, María Lucía Mesa Rubio, Referencia : Pediatr Pulmonol . 2025 Mar;60(3):e27495. doi: 10.1002/ppul.27495. DOI (Digital Object Identifier) : 10.1002/ppul.27495 PMID : 40018994 Derechos de uso : CC BY-NC-ND En línea : https://pubmed.ncbi.nlm.nih.gov/40018994/ Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis Reserva
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