First report of survival in two patients with hematologic malignancy and Stenotrophomonas maltophilia hemorrhagic pneumonia treated with trimethoprim-sulfamethoxazole-based combination antibiotic therapy [documento electrónico] / Nelson Darío Giraldo Ramírez, ; Óscar Iván McEwen Tamayo, ; Alicia Inés Hidrón Botero,  . - 2020.
Obra : Journal of Infection and Chemotherapy

Idioma : Inglés (eng)

Palabras clave :	Combination therapy  Hemorrhagic pneumonia  Stenotrophomonas maltophilia  Trimethoprim-sulfamethoxazole
Resumen :	Stenotrophomonas maltophilia has become a common cause of opportunistic infections in immunocompromised hosts and critical care patients. The most common disease manifestations are pneumonia and bacteremia, with a mortality ranging from 9% to 60.5% depending of the type of infection and host related underlying risk factors. Patients with hematological malignancies may develop a hemorrhagic pneumonia with a rapidly progressive and universally fatal disease course, despite appropriate treatment with trimethoprim/sulfamethoxazole or combination therapy. We report the first two patients with hematologic malignancies and hemorrhagic pneumonia due to S. maltophilia with successful treatment outcomes after early institution of combination therapy with TMP/SMX, polymyxin, and/or moxifloxacin.
Mención de responsabilidad :	Sara Catalina Penagos, Nelson Giraldo, Camilo Vallejo, Oscar McEwen, Alicia Hidron
Referencia :	J Infect Chemother. 2020 Apr;26(4):397-399.
DOI (Digital Object Identifier) :	10.1016/j.jiac.2019.12.003
PMID :	31882384
En línea :	https://linkinghub.elsevier.com/retrieve/pii/S1341-321X(19)30371-X
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5076