| Título : |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease |
| Tipo de documento : |
documento electrónico |
| Autores : |
Leonardo Fabio Moreno Gómez, |
| Fecha de publicación : |
2021 |
| Títulos uniformes : |
Clinical Neurophysiology
|
| Idioma : |
Inglés (eng) |
| Palabras clave : |
Alpha rhythm Electroencephalography Neuropsychological tests Parkinson’s Disease Theta rhythm |
| Resumen : |
Objective: To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson's Disease (PD) non-demented patients. Methods: 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results: The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions: Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance: Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. |
| Mención de responsabilidad : |
Alberto Jaramillo-Jimenez, Jazmin Ximena Suarez-Revelo, John Fredy Ochoa-Gomez, Jairo Alexander Carmona Arroyave, Yamile Bocanegra, Francisco Lopera, Omar Buriticá, David Antonio Pineda-Salazar, Leonardo Moreno Gómez, Carlos Andrés Tobón Quintero, Miguel Germán Borda, Laura Bonanni, Dominic H Ffytche, Kolbjørn Brønnick, Dag Aarsland |
| Referencia : |
Clin Neurophysiol. 2021 Jan 13;132(3):756-764. |
| DOI (Digital Object Identifier) : |
10.1016/j.clinph.2021.01.001 |
| PMID : |
33571883 |
| En línea : |
https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(21)00003-1 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5758 |
Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease [documento electrónico] / Leonardo Fabio Moreno Gómez, . - 2021. Obra : Clinical NeurophysiologyIdioma : Inglés ( eng) | Palabras clave : |
Alpha rhythm Electroencephalography Neuropsychological tests Parkinson’s Disease Theta rhythm |
| Resumen : |
Objective: To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson's Disease (PD) non-demented patients. Methods: 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results: The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions: Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance: Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. |
| Mención de responsabilidad : |
Alberto Jaramillo-Jimenez, Jazmin Ximena Suarez-Revelo, John Fredy Ochoa-Gomez, Jairo Alexander Carmona Arroyave, Yamile Bocanegra, Francisco Lopera, Omar Buriticá, David Antonio Pineda-Salazar, Leonardo Moreno Gómez, Carlos Andrés Tobón Quintero, Miguel Germán Borda, Laura Bonanni, Dominic H Ffytche, Kolbjørn Brønnick, Dag Aarsland |
| Referencia : |
Clin Neurophysiol. 2021 Jan 13;132(3):756-764. |
| DOI (Digital Object Identifier) : |
10.1016/j.clinph.2021.01.001 |
| PMID : |
33571883 |
| En línea : |
https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(21)00003-1 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5758 |
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