Título :	Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Splenomegaly and Focal Splenic Lesion: Is It Safe, Effective and Necessary?
Tipo de documento :	documento electrónico
Autores :	Gabriel Alonso Mosquera Klinger,
Fecha de publicación :	2020
Títulos uniformes :	Revista Española de Enfermedades Digestivas
Idioma :	Inglés (eng)
Resumen :	Introduction: splenomegaly and/or focal splenic lesions (FSL) have limited histopathologic studies due to the risk posed by splenic punctures. Percutaneous biopsies with a fine needle are difficult, especially due to interposition of gases, ascites, obesity or a history of abdominal surgery. On the other hand, endoscopic ultrasound (EUS) takes advantage of the proximity of the gastric wall to the spleen in order to puncture and visualize the needle and its movements in real time. Objective: to describe the initial experience and results obtained with EUS-FNA in patients with splenomegaly or FSL. Materials and methods: this was a descriptive observational study. EUS-FNA of the spleen was performed with a slow-pull technique, which avoided fanning with an average of 3 needle passes. Biopsies were sent in Cytorich RedTM solution for analysis by cytology and cell block. Results: punctures were performed in 15 patients (9 females) and the median age was 67 years (range 44-86). Patients studied due to an enlarged spleen or splenic FSL, in the context of fever of an unknown origin, adenopathies and abnormal weight loss were included. A conclusive diagnosis was achieved by EUS-FNA in 10 patients (66.7 %), 4 were large cell type B non-Hodgkin's lymphoma and one Hodgkin's lymphoma. There were no immediate or delayed complications related to the procedure. Conclusions: EUS-guided splenic punctures appear to be safe, effective and may be necessary in some clinical settings in order to complete the etiologic filiation of splenomegaly of an uncertain origin or FSL and to rule out malignancy.
Mención de responsabilidad :	Gabriel Mosquera-Klinger, Carlos de la Serna Higuera, Sergio Bazaga, Francisco Javier García-Alonso, Ramón Sánchez Ocaña, Beatriz Antolín Melero, Marina de Benito Sanz, Beatriz Madrigal, Ángeles Torres, Manuel Pérez-Miranda
Referencia :	Rev Esp Enferm Dig. 2020 May;112(5):355-359.
DOI (Digital Object Identifier) :	10.17235/reed.2020.6667/2019
PMID :	32338025
En línea :	https://online.reed.es/DOI/PDF/ArticuloDOI_6667.pdf
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5098

Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Splenomegaly and Focal Splenic Lesion: Is It Safe, Effective and Necessary? [documento electrónico] / Gabriel Alonso Mosquera Klinger,  . - 2020.
Obra : Revista Española de Enfermedades Digestivas

Idioma : Inglés (eng)

Resumen :	Introduction: splenomegaly and/or focal splenic lesions (FSL) have limited histopathologic studies due to the risk posed by splenic punctures. Percutaneous biopsies with a fine needle are difficult, especially due to interposition of gases, ascites, obesity or a history of abdominal surgery. On the other hand, endoscopic ultrasound (EUS) takes advantage of the proximity of the gastric wall to the spleen in order to puncture and visualize the needle and its movements in real time. Objective: to describe the initial experience and results obtained with EUS-FNA in patients with splenomegaly or FSL. Materials and methods: this was a descriptive observational study. EUS-FNA of the spleen was performed with a slow-pull technique, which avoided fanning with an average of 3 needle passes. Biopsies were sent in Cytorich RedTM solution for analysis by cytology and cell block. Results: punctures were performed in 15 patients (9 females) and the median age was 67 years (range 44-86). Patients studied due to an enlarged spleen or splenic FSL, in the context of fever of an unknown origin, adenopathies and abnormal weight loss were included. A conclusive diagnosis was achieved by EUS-FNA in 10 patients (66.7 %), 4 were large cell type B non-Hodgkin's lymphoma and one Hodgkin's lymphoma. There were no immediate or delayed complications related to the procedure. Conclusions: EUS-guided splenic punctures appear to be safe, effective and may be necessary in some clinical settings in order to complete the etiologic filiation of splenomegaly of an uncertain origin or FSL and to rule out malignancy.
Mención de responsabilidad :	Gabriel Mosquera-Klinger, Carlos de la Serna Higuera, Sergio Bazaga, Francisco Javier García-Alonso, Ramón Sánchez Ocaña, Beatriz Antolín Melero, Marina de Benito Sanz, Beatriz Madrigal, Ángeles Torres, Manuel Pérez-Miranda
Referencia :	Rev Esp Enferm Dig. 2020 May;112(5):355-359.
DOI (Digital Object Identifier) :	10.17235/reed.2020.6667/2019
PMID :	32338025
En línea :	https://online.reed.es/DOI/PDF/ArticuloDOI_6667.pdf
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5098