Disseminated Cryptococcosis After Liver Transplant: A Case Report [documento electrónico] / Juan Ignacio Marín Zuluaga, ; Octavio Germán Muñoz Maya, ; Óscar Mauricio Santos Sánchez, ; Isabel Cristina Ramírez Sánchez, ; Juan Carlos Restrepo Gutiérrez,  . - 2020.
Obra : Experimental and Clinical Transplantation

Idioma : Inglés (eng)

Palabras clave :	Cryptococcus neoformans  Joint pain  Liver cirrhosis
Resumen :	Cryptococcosis is an opportunistic infection caused by the Basidiomycota Cryptococcus neoformans (Cryptococcus gattii), which affects immunosuppressed patients and less frequently immunocompetent patients. Solid-organ transplant recipients are a particularly high-risk group, depending on the net state of immunosuppression. In these patients, the infection usually appears after the first year after transplant, although it may occur earlier in liver transplant recipients. In most cases, the infection is secondary to the reactivation of a latent infection, although it may be due to an unidentified pretransplant infection by primary infection. Less frequently, it may be transmitted by the graft. The lung and central nervous system are most frequently involved. Extrapulmonary involvement is seen in 75% of the cases, and disseminated disease occurs in 61%, with mortality ranging from 17% to 50% when the central nervous system is involved. Here, we report a case of disseminated cryptococcosis (lymphadenitis, meningitis, pulmonary nodules, and possibly sacroiliitis) in a patient after liver transplant, with good clinical and micro-biological outcomes and without relapse.
Mención de responsabilidad :	Gabriel Sebastián Díaz-Ramírez, Omar Yesid Martínez-Casas, Juan Ignacio Marín-Zuluaga, Octavio Muñoz-Maya, Óscar Santos-Sánchez, Isabel Cristina Ramírez, Juan Carlos Restrepo-Gutiérrez
Referencia :	Exp Clin Transplant. 2020 Jun;18(3):402-406.
DOI (Digital Object Identifier) :	10.6002/ect.2018.0051
PMID :	30696395
En línea :	http://www.ectrx.org/forms/ectrxcontentshow.php?doi_id=10.6002/ect.2018.0051
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5106