Profile resistance of pathogens causing urinary tract infection in the pediatric population, and antibiotic treatment response, at a University Hospital 2010-2011 = Perfil de resistencia de los patógenos causantes de infección urinaria en la población pediátrica y respuesta al tratamiento antibiótico, en un hospital universitario 2010-2011 [documento electrónico] / Catalina Vélez Echeverri, ; Lina Maria Serna Higuita, ; Ana María Bedoya Londoño, ; Margarita María Suárez Galvis, ; Catalina Hincapié Ocampo, ; Adriana Isabel Henao López, ; Diana C. Ortíz M., ; Juan José Vanegas Ruiz, ; John Jairo Zuleta Tobón, ; David Andrés Espinal Botero,  . - 2014.
Obra : Colombia Médica

Idioma : Inglés (eng)

Palabras clave :	Urinary tract infection  drug resistance  bacterial  Escherichia coli
Resumen :	Introduction: Urinary tract infection (UTI) is one of the most common bacterial infections in childhood and causes acute and chronic morbidity and long-term hypertension and chronic kidney disease. Objectives: To describe the demographic characteristics, infectious agents, patterns of antibiotic resistance, etiologic agent and profile of susceptibility and response to empirical treatment of UTI in a pediatric population. Methods: This is a descriptive, retrospective study. Results: Included in the study were 144 patients, 1:2.06 male to female ratio. The most common symptom was fever (79.9%) and 31.3% had a history of previous UTI. 72.0% of the patients had positive urine leukocyte count (>5 per field), urine gram was positive in 85.0% of samples and gram negative bacilli accounted for 77.8% for the total pathogens isolated. The most frequent uropathogens isolated were Escherichia coli and Klebsiella pneumoniae. Our E.coli isolates had a susceptibility rate higher than 90% to most of the antibiotics used, but a resistance rate of 42.6% to TMP SMX and 45.5% to ampicillin sulbactam. 6.3% of E. coliwas extended-spectrum beta-lactamases producer strains. The most frequent empirical antibiotic used was amikacin, which was used in 66.0% of the patients. 17 of 90 patients who underwent voiding cistouretrography (VCUG) had vesicoureteral reflux. Conclusion: This study revealed that E. coli was the most frequent pathogen of community acquired UTI. We found that E. coli and other uropathogens had a high resistance rate against TMP SMX and ampicillin sulbactam. In order to ensure a successful empirical treatment, protocols should be based on local epidemiology and susceptibility rates.
Mención de responsabilidad :	Catalina Vélez Echeverri, Lina María Serna-Higuita, Ana Katherina Serrano, Carolina Ochoa-García, Luisa Rojas Rosas, Ana María Bedoya, Margarita Suárez, Catalina Hincapié, Adriana Henao, Diana Ortiz, Juan José Vanegas, John Jairo Zuleta, David Espinal
Referencia :	Colomb Med (Cali). 2014 Mar 30;45(1):39-44.
DOI (Digital Object Identifier) :	10.25100/cm.v45i1.1318
PMID :	24970958
Derechos de uso :	CC BY-NC-ND
En línea :	https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1318
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5721