| Título : | 
					Precocious puberty in a healthy 2 years old girl: Ovarian Sertoli-Leydig cells cancer | 
				 
					| Tipo de documento :  | 
					documento electrónico | 
				 
					| Autores :  | 
					Jennyfer Monroy Espejo,  ; Carolina Jaramillo Arango,  | 
				 
					| Fecha de publicación :  | 
					2021 | 
				 
					| Títulos uniformes : | 
					 Journal of Clinical and Translational Endocrinology: Case Reports
  | 
				 
					| Idioma : | 
					Inglés (eng) | 
				 
					| Resumen :  | 
					Precocious puberty refers to appearance of secondary sexual characteristics, increased growth rate and reproductive capacity before 8 years in girls, and 9 years in boys. The etiology can be diverse, either central activation of hypothalamus-pituitary gonadal axis or by endogenous production or exogenous administration of sex steroids. Peripheral precocious puberty is less common and Leydig-Sertoli cell tumors comprise 1–2% of the pediatric ovarian malignancies. These tumors commonly present in the second or third decade of life but can present as early as 2-years of age. We describe a case of precocious puberty caused by ovarian Sertoli-Leydig cancer in a young girl with no pre-existing medical issues. The 2-year-old patient was referred from Saint Martin to the Pediatric endocrinology for evaluation of pubic hair and breast development which started 3-month prior to presentation. On exam, the patient was noted to have abdominal prominence which prompted obtaining abdominal imaging which showed an ovarian tumor which was subsequently removed. | 
				 
					| Mención de responsabilidad :  | 
					Jennifer Monroy, Carolina Jaramillo y Sasha González | 
				 
					| DOI (Digital Object Identifier) :  | 
					10.1016/j.jecr.2021.100090 | 
				 
					| Derechos de uso :  | 
					CC BY-NC-ND | 
				 
					| En línea :  | 
					https://linkinghub.elsevier.com/retrieve/pii/S2214624521000137 | 
				 
					| Enlace permanente : | 
					https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis | 
				  
 
					Precocious puberty in a healthy 2 years old girl: Ovarian Sertoli-Leydig cells cancer [documento electrónico] /  Jennyfer Monroy Espejo,  ;  Carolina Jaramillo Arango,  . - 2021. Obra :   Journal of Clinical and Translational Endocrinology: Case ReportsIdioma : Inglés ( eng) 
					| Resumen :  | 
					Precocious puberty refers to appearance of secondary sexual characteristics, increased growth rate and reproductive capacity before 8 years in girls, and 9 years in boys. The etiology can be diverse, either central activation of hypothalamus-pituitary gonadal axis or by endogenous production or exogenous administration of sex steroids. Peripheral precocious puberty is less common and Leydig-Sertoli cell tumors comprise 1–2% of the pediatric ovarian malignancies. These tumors commonly present in the second or third decade of life but can present as early as 2-years of age. We describe a case of precocious puberty caused by ovarian Sertoli-Leydig cancer in a young girl with no pre-existing medical issues. The 2-year-old patient was referred from Saint Martin to the Pediatric endocrinology for evaluation of pubic hair and breast development which started 3-month prior to presentation. On exam, the patient was noted to have abdominal prominence which prompted obtaining abdominal imaging which showed an ovarian tumor which was subsequently removed. | 
				 
					| Mención de responsabilidad :  | 
					Jennifer Monroy, Carolina Jaramillo y Sasha González | 
				 
					| DOI (Digital Object Identifier) :  | 
					10.1016/j.jecr.2021.100090 | 
				 
					| Derechos de uso :  | 
					CC BY-NC-ND | 
				 
					| En línea :  | 
					https://linkinghub.elsevier.com/retrieve/pii/S2214624521000137 | 
				 
					| Enlace permanente : | 
					https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis | 
				 
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