Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents [documento electrónico] / Andrea Victoria Restrepo Gouzy, ; Mónica Rosa Trujillo Honeysberg,  . - 2022.
Obra : International Journal of Infectious Diseases

Idioma : Inglés (eng)

Palabras clave :	Induced sputum  adolescents  children  diagnosis  etiology  pneumonia
Resumen :	Objectives: This study aimed to evaluate the utility of induced sputum (IS) for the diagnosis of community-acquired pneumonia (CAP) in pediatric population. Methods: This cross-sectional study included pediatric population aged between 1 month and 17 years who were hospitalized with a diagnosis of CAP in 13 hospitals in Colombia, in whom an IS sample was obtained. Gram staining, aerobic bacterial and mycobacterial culture tests, and polymerase chain reaction (PCR) for 6 atypical bacteria and 15 respiratory viruses were performed. We evaluated the quality of IS samples. Results: IS samples were collected in 516 of 525 children included in this study. The median age was 32 months, 38.6% were younger than 2 years, and 40.9% were between 2 and 5 years. Two patients had transient hypoxemia during the procedure. The quality of the IS obtained was good in 48.4% and intermediate in 24.5%. Identification of a respiratory pathogen was achieved with an IS sample (with Gram staining, culture test, and PCR) in 372 of 516 children with CAP. Conclusion: Our study shows that IS is an adequate sample for the diagnosis of CAP in pediatric population that required hospitalization. The procedure was safe, well tolerated, and with better diagnostic yields compared with the rest of the samples obtained.
Mención de responsabilidad :	Zulma Vanessa Rueda, Marcela Bermúdez, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Luisa Fernanda Carmona, Catalina Arango, Jose Luis Albarracín, Lucelly López, Yudy Aguilar, María Angélica Maya, Mónica Trujillo, Ángela Rocio Copete, Cristian Vera, Mariana Herrera, Margarita Rosa Giraldo, Gloria Isabel Niño-Cruz, Lázaro A Vélez
Referencia :	Int J Infect Dis. 2022 Jan 19;116:348-354.
DOI (Digital Object Identifier) :	10.1016/j.ijid.2022.01.026
PMID :	35063681
Derechos de uso :	CC BY-NC-ND
En línea :	https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(22)00025-X
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6010