[Publicación periódica] 

Título :	In vivo absolute quantification of carnosine in the vastus lateralis muscle with 1H MRS using a surface coil and water as internal reference
Tipo de documento :	documento electrónico
Autores :	Vega, Gloria, Autor ; Ricaurte, German, Autor ; Mauricio Estrada Castrillón, Autor ; Reyngoudt, Harmen, Autor ; Cardona, Oscar M., Autor ; Gallo Villegas, Jaime A., Autor ; Narváez Sánchez, Raúl, Autor ; Calderón, Juan C., Autor
Fecha de publicación :	2023
ISBN/ISSN/DL :	98700011900
Idioma :	Inglés (eng)
Materias :	Carnosine
Palabras clave :	Carnosine  Proton magnetic resonance spectroscopy  Skeletal muscle  Vastus lateralis  Gastrocnemius
Clasificación:	AC-2023-001
Resumen :	Phantom’s experiments showed a maximum error of 7%, highlighting the validity of the measurements in the study setup. The carnosine concentrations (mmol/kg ww, mean?±?SD) measured in the GM were 6.8?±?2.2 with the VC (CcarVC) and 10.2?±?3.0 with the SC (CcarSC) (P?=?0.013; n?=?9). Therefore, a correction was applied to these measurements (CcarVC?=?0.6582*CcarSC), to make coils performance comparable (6.8?±?2.2 for VC and 6.7?±?2.0 for SC, P?=?0.97). After that, only the SC was used to quantify carnosine in the VLM, where a concentration of 5.4?±?1.5 (n?=?30) was found, with significant differences between men (6.2?±?1.3; n?=?15) and women (4.6?±?1.2; n?=?15). The error in quantitation was 5.3–5.5% with both coils.
Nota de contenido :	To standardize a method for 1H MRS intramuscular absolute quantification of carnosine in the thigh, using a surface coil and water as internal reference.
Derechos de uso :	Permiso de republicación otorgado al HPTU
En línea :	https://link.springer.com/article/10.1007/s00256-022-04149-8
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6164

[Publicación periódica] In vivo absolute quantification of carnosine in the vastus lateralis muscle with 1H MRS using a surface coil and water as internal reference [documento electrónico] / Vega, Gloria, Autor ; Ricaurte, German, Autor ; Mauricio Estrada Castrillón, Autor ; Reyngoudt, Harmen, Autor ; Cardona, Oscar M., Autor ; Gallo Villegas, Jaime A., Autor ; Narváez Sánchez, Raúl, Autor ; Calderón, Juan C., Autor . - 2023.
ISSN : 98700011900
Idioma : Inglés (eng)

Materias :	Carnosine
Palabras clave :	Carnosine  Proton magnetic resonance spectroscopy  Skeletal muscle  Vastus lateralis  Gastrocnemius
Clasificación:	AC-2023-001
Resumen :	Phantom’s experiments showed a maximum error of 7%, highlighting the validity of the measurements in the study setup. The carnosine concentrations (mmol/kg ww, mean?±?SD) measured in the GM were 6.8?±?2.2 with the VC (CcarVC) and 10.2?±?3.0 with the SC (CcarSC) (P?=?0.013; n?=?9). Therefore, a correction was applied to these measurements (CcarVC?=?0.6582*CcarSC), to make coils performance comparable (6.8?±?2.2 for VC and 6.7?±?2.0 for SC, P?=?0.97). After that, only the SC was used to quantify carnosine in the VLM, where a concentration of 5.4?±?1.5 (n?=?30) was found, with significant differences between men (6.2?±?1.3; n?=?15) and women (4.6?±?1.2; n?=?15). The error in quantitation was 5.3–5.5% with both coils.
Nota de contenido :	To standardize a method for 1H MRS intramuscular absolute quantification of carnosine in the thigh, using a surface coil and water as internal reference.
Derechos de uso :	Permiso de republicación otorgado al HPTU
En línea :	https://link.springer.com/article/10.1007/s00256-022-04149-8
Enlace permanente :	https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6164