| Título : |
Is tPA/DNase Effective Routine Initial Therapy for Pleural Empyema? |
| Tipo de documento : |
documento electrónico |
| Autores : |
Willfredy Castaño Ruiz, Autor ; Liberman, Moishe, Autor |
| Fecha de publicación : |
2025 |
| Títulos uniformes : |
Springer
|
| Idioma : |
Inglés (eng) |
| Resumen : |
Following the validation of intrapleural tPA/DNAse therapy for the treatment of pleural empyema by the MIST-2 trial, the medical community has shifted the management approach for empyema, favoring less aggressive alternatives to surgery with good results. Our comprehensive literature review revealed that the treatment of empyema with a tPA/DNase regimen has been proven effective in the management of stage 2 empyema, decreasing the need for surgical intervention. However, direct comparative analyses between this treatment strategy and surgery have not yielded statistically significant differences. |
| Mención de responsabilidad : |
Willfredy Castano & Moishe Liberman |
| DOI (Digital Object Identifier) : |
10.1007/978-3-031-78663-1_50 |
| Derechos de uso : |
CC BY-NC-ND |
| En línea : |
https://link.springer.com/chapter/10.1007/978-3-031-78663-1_50 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
Is tPA/DNase Effective Routine Initial Therapy for Pleural Empyema? [documento electrónico] / Willfredy Castaño Ruiz, Autor ; Liberman, Moishe, Autor . - 2025. Obra : SpringerIdioma : Inglés ( eng)
| Resumen : |
Following the validation of intrapleural tPA/DNAse therapy for the treatment of pleural empyema by the MIST-2 trial, the medical community has shifted the management approach for empyema, favoring less aggressive alternatives to surgery with good results. Our comprehensive literature review revealed that the treatment of empyema with a tPA/DNase regimen has been proven effective in the management of stage 2 empyema, decreasing the need for surgical intervention. However, direct comparative analyses between this treatment strategy and surgery have not yielded statistically significant differences. |
| Mención de responsabilidad : |
Willfredy Castano & Moishe Liberman |
| DOI (Digital Object Identifier) : |
10.1007/978-3-031-78663-1_50 |
| Derechos de uso : |
CC BY-NC-ND |
| En línea : |
https://link.springer.com/chapter/10.1007/978-3-031-78663-1_50 |
| Enlace permanente : |
https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_dis |
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Is tPA/DNase Effective Routine Initial Therapy for Pleural Empyema?
