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Autor John Fredy Nieto Ríos
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Médico Internista Nefrólogo, Hospital Pablo Tobón Uribe
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Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient / John Fredy Nieto Ríos ; Catalina Ocampo Kohn ; Arbey Aristizabal Álzate ; Lina Maria Serna Higuita ; Isabel Cristina Ramírez Sánchez ; Gustavo Adolfo Zuluaga Valencia
Título : Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Arbey Aristizabal Álzate, ; Lina Maria Serna Higuita, ; Isabel Cristina Ramírez Sánchez, ; Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2014 Títulos uniformes : Nefrología Idioma : Inglés (eng) Palabras clave : Mucormycosis rhino-orbital-cerebral kidney transplantation acute rejection immunosuppression Resumen : Rhino-orbital-cerebral mucormycosis is a potentially fatal mycotic infection in immunosuppressed patients. The main risk factors for acquiring this infection are poorly controlled diabetes mellitus, iron overload, potent immunosuppression and chronic steroid use. In this review, we present the case of a kidney transplant patient who, after treatment of an acute rejection episode with high doses of steroids and potent immunosuppression with tacrolimus and mycophenolate, presented with rapidly progressing rhino-orbital-cerebral mucormycosis that required aggressive surgical treatment, immunosuppression discontinuation and potent antifungal treatment. Mención de responsabilidad : John F Nieto-Ríos, Luis F Moreno-Coral, Andrés Zapata-Cárdenas, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Lina M Serna-Higuita, Isabel C Ramírez-Sánchez, Gustavo A Zuluaga-Valencia Referencia : Nefrologia. 2014;34(1):120-4. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2013.Nov.12084 PMID : 24463869 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/en-successful-treatment-rhino-orbital-cerebral [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3771 Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient [documento electrónico] / John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Arbey Aristizabal Álzate, ; Lina Maria Serna Higuita, ; Isabel Cristina Ramírez Sánchez, ; Gustavo Adolfo Zuluaga Valencia, . - 2014.
Obra : Nefrología
Idioma : Inglés (eng)
Palabras clave : Mucormycosis rhino-orbital-cerebral kidney transplantation acute rejection immunosuppression Resumen : Rhino-orbital-cerebral mucormycosis is a potentially fatal mycotic infection in immunosuppressed patients. The main risk factors for acquiring this infection are poorly controlled diabetes mellitus, iron overload, potent immunosuppression and chronic steroid use. In this review, we present the case of a kidney transplant patient who, after treatment of an acute rejection episode with high doses of steroids and potent immunosuppression with tacrolimus and mycophenolate, presented with rapidly progressing rhino-orbital-cerebral mucormycosis that required aggressive surgical treatment, immunosuppression discontinuation and potent antifungal treatment. Mención de responsabilidad : John F Nieto-Ríos, Luis F Moreno-Coral, Andrés Zapata-Cárdenas, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Lina M Serna-Higuita, Isabel C Ramírez-Sánchez, Gustavo A Zuluaga-Valencia Referencia : Nefrologia. 2014;34(1):120-4. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2013.Nov.12084 PMID : 24463869 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/en-successful-treatment-rhino-orbital-cerebral [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3771 Reserva
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2014-012.pdfAdobe Acrobat PDF Tuberculosis in renal transplant patients: the experience of a single center in Medellín-Colombia, 2005-2013 / Lina Maria Serna Higuita ; John Fredy Nieto Ríos ; Catalina Ocampo Kohn ; Arbey Aristizabal Álzate ; Catalina Vélez Echeverri ; Juan José Vanegas Ruiz ; Isabel Cristina Ramírez Sánchez ; John Jairo Zuleta Tobón ; Gustavo Adolfo Zuluaga Valencia
Título : Tuberculosis in renal transplant patients: the experience of a single center in Medellín-Colombia, 2005-2013 Tipo de documento : documento electrónico Autores : Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Arbey Aristizabal Álzate, ; Catalina Vélez Echeverri, ; Juan José Vanegas Ruiz, ; Isabel Cristina Ramírez Sánchez, ; John Jairo Zuleta Tobón, ; Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2014 Títulos uniformes : Brazilian Journal of Nephrology Idioma : Inglés (eng) Palabras clave : Graft rejection kidney transplantation mycobacterium tuberculosis Resumen : Introduction: Tuberculosis is a common opportunistic infection in renal transplant patients. Objective: To obtain a clinical and laboratory description of transplant patients diagnosed with tuberculosis and their response to treatment during a period ranging from 2005 to 2013 at the Pablo Tobón Uribe Hospital. Methods: Retrospective and descriptive study. Results: In 641 renal transplants, tuberculosis was confirmed in 12 cases. Of these, 25% had a history of acute rejection, and 50% had creatinine levels greater than 1.5 mg/dl prior to infection. The disease typically presented as pulmonary (50%) and disseminated (33.3%). The first phase of treatment consisted of 3 months of HZRE (isoniazid, pyrazinamide, rifampicin and ethambutol) in 75% of the cases and HZME (isoniazid, pyrazinamide, moxifloxacin and ethambutol) in 25% of the cases. During the second phase of the treatment, 75% of the cases received isoniazid and rifampicin, and 25% of the cases received isoniazid and ethambutol. The length of treatment varied between 6 and 18 months. In 41.7% of patients, hepatotoxicity was associated with the beginning of anti-tuberculosis therapy. During a year-long follow-up, renal function remained stable, and the mortality rate was 16.7%. Conclusion: Tuberculosis in the renal transplant population studied caused diverse nonspecific symptoms. Pulmonary and disseminated tuberculosis were the most frequent forms and required prolonged treatment. Antituberculosis medications had a high toxicity and mortality. This infection must be considered when patients present with a febrile syndrome of unknown origin, especially during the first year after renal transplant. Mención de responsabilidad : Lina Maria Serna Higuita, John Fredy Nieto-Ríos, Salomon Daguer-Gonzalez, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Catalina Velez-Echeverri, Juan Jose Vanegas-Ruiz, Isabel Ramirez-Sanchez, Jhon Jairo Zuleta Tobon, Gustavo Adolfo Zuluaga-Valencia Referencia : J Bras Nefrol. 2014 Oct-Dec;36(4):512-8. DOI (Digital Object Identifier) : 10.5935/0101-2800.20140073 PMID : 25517281 Derechos de uso : CC BY-NC En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002014000400512&l [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4546 Tuberculosis in renal transplant patients: the experience of a single center in Medellín-Colombia, 2005-2013 [documento electrónico] / Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Arbey Aristizabal Álzate, ; Catalina Vélez Echeverri, ; Juan José Vanegas Ruiz, ; Isabel Cristina Ramírez Sánchez, ; John Jairo Zuleta Tobón, ; Gustavo Adolfo Zuluaga Valencia, . - 2014.
Obra : Brazilian Journal of Nephrology
Idioma : Inglés (eng)
Palabras clave : Graft rejection kidney transplantation mycobacterium tuberculosis Resumen : Introduction: Tuberculosis is a common opportunistic infection in renal transplant patients. Objective: To obtain a clinical and laboratory description of transplant patients diagnosed with tuberculosis and their response to treatment during a period ranging from 2005 to 2013 at the Pablo Tobón Uribe Hospital. Methods: Retrospective and descriptive study. Results: In 641 renal transplants, tuberculosis was confirmed in 12 cases. Of these, 25% had a history of acute rejection, and 50% had creatinine levels greater than 1.5 mg/dl prior to infection. The disease typically presented as pulmonary (50%) and disseminated (33.3%). The first phase of treatment consisted of 3 months of HZRE (isoniazid, pyrazinamide, rifampicin and ethambutol) in 75% of the cases and HZME (isoniazid, pyrazinamide, moxifloxacin and ethambutol) in 25% of the cases. During the second phase of the treatment, 75% of the cases received isoniazid and rifampicin, and 25% of the cases received isoniazid and ethambutol. The length of treatment varied between 6 and 18 months. In 41.7% of patients, hepatotoxicity was associated with the beginning of anti-tuberculosis therapy. During a year-long follow-up, renal function remained stable, and the mortality rate was 16.7%. Conclusion: Tuberculosis in the renal transplant population studied caused diverse nonspecific symptoms. Pulmonary and disseminated tuberculosis were the most frequent forms and required prolonged treatment. Antituberculosis medications had a high toxicity and mortality. This infection must be considered when patients present with a febrile syndrome of unknown origin, especially during the first year after renal transplant. Mención de responsabilidad : Lina Maria Serna Higuita, John Fredy Nieto-Ríos, Salomon Daguer-Gonzalez, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Catalina Velez-Echeverri, Juan Jose Vanegas-Ruiz, Isabel Ramirez-Sanchez, Jhon Jairo Zuleta Tobon, Gustavo Adolfo Zuluaga-Valencia Referencia : J Bras Nefrol. 2014 Oct-Dec;36(4):512-8. DOI (Digital Object Identifier) : 10.5935/0101-2800.20140073 PMID : 25517281 Derechos de uso : CC BY-NC En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002014000400512&l [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4546 Reserva
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2014-114.pdfAdobe Acrobat PDF Sickle cell crisis and acute humoural rejection in kidney graft / John Fredy Nieto Ríos ; Lina Maria Serna Higuita ; Gustavo Adolfo Zuluaga Valencia ; Arbey Aristizabal Álzate ; Catalina Ocampo Kohn
Título : Sickle cell crisis and acute humoural rejection in kidney graft Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Lina Maria Serna Higuita, ; Gustavo Adolfo Zuluaga Valencia, ; Arbey Aristizabal Álzate, ; Catalina Ocampo Kohn, Fecha de publicación : 2013 Títulos uniformes : Nefrología Idioma : Inglés (eng) Mención de responsabilidad : John F Nieto-Ríos, Lina M Serna-Higuita, Ana K Serrano-Gayubo, Arbey Aristizabal-Alzate, Catalina Ocampo-Kohn, Rafael Andrade-Pérez, Gustavo Zuluaga-Valencia Referencia : Nefrologia. 2013;33(2):286-8. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2012.Oct.11760 PMID : 23511772 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/es-linkresolver-crisis-falciforme-rechazo-agud [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3717 Sickle cell crisis and acute humoural rejection in kidney graft [documento electrónico] / John Fredy Nieto Ríos, ; Lina Maria Serna Higuita, ; Gustavo Adolfo Zuluaga Valencia, ; Arbey Aristizabal Álzate, ; Catalina Ocampo Kohn, . - 2013.
Obra : Nefrología
Idioma : Inglés (eng)
Mención de responsabilidad : John F Nieto-Ríos, Lina M Serna-Higuita, Ana K Serrano-Gayubo, Arbey Aristizabal-Alzate, Catalina Ocampo-Kohn, Rafael Andrade-Pérez, Gustavo Zuluaga-Valencia Referencia : Nefrologia. 2013;33(2):286-8. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2012.Oct.11760 PMID : 23511772 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/es-linkresolver-crisis-falciforme-rechazo-agud [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3717 Reserva
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2013-058.pdfAdobe Acrobat PDF Survival of renal transplantation patients older than 60 years: a single-center experience / John Fredy Nieto Ríos ; Lina Maria Serna Higuita
Título : Survival of renal transplantation patients older than 60 years: a single-center experience Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Lina Maria Serna Higuita, Fecha de publicación : 2013 Títulos uniformes : Transplantation Proceedings Idioma : Inglés (eng) Resumen : Background: Elderly patients are the fastest growing population requiring renal replacement therapy. It has been stated that renal transplantation may be the best treatment option for these patients. However, it has been observed that older patients have a higher mortality rate than those who are younger. Yet the factors that determine post-transplantation outcomes in this population remain poorly defined. The aims of this study were to evaluate the graft and patient survival in kidney transplant recipients who are older than 60 years of age to identify relevant predictive factors. Methods: In this population-based retrospective cohort study of 201 kidney transplantations performed in elderly patients from January 2002 throughout June 2009, we estimated the 1-,3-,and 5-year patients and graft survival rates. We also evaluated the complications and the predictors of poor outcomes. Survival times were analyzed using the Kaplan–Meier method and survival differences assessed with Mantel-Cox log rank-test. We performed a Cox proportional hazards regression models to evaluate the impact of baseline and treatment characteristics on patient and graft survival. Results: Graft and patient survival rates at 1, 3, and 5 years were 76.4%, 71.3%, and 54.3%, and 78.2%, 73.8%, and 56.4%, respectively. Graft survival rates censored for patient death with a functioning graft were 93.1, 92.1, and 89%. Patient survival rates differed between diabetic and nondiabetic subjects at 1, 3 and 5 years (69.5% versus 83.6%; 59.8% versus 72.3%; 43.6% versus 65.7%; P = .008). On multivariate analysis, the factors associated with patients survival were diabetes mellitus (hazard ratio [HR] 2.058, 95% confidence interval [CI] 1.173–3.611, P = .012) and the 1-month serum creatinine value was > 1.6 mg/dL (HR 2.108 for each point increase, 95% CI 1.521–2.921, P = .000). Furthermore, there was an insignificant trend forward an association between active or past smoker and lower patient survival (HR 1.689, 95% CI 0.937–3.043, P = .08). The main causes of graft loss were patient death (79.5%). acute rejection (6.8%), and chronic allograft nephropathy (5.5%). Conclusion: Renal transplantation can be performed safely and with acceptable outcomes in elderly patients after appropriate clinical evaluation. The grafts show excellent survival albeit that deaths with a functional graft continue to be an important issue. Mención de responsabilidad : J R Rodelo, J F Nieto-Ríos, L M Serna-Higuita, J E Henao, A García, A C Reino, J C Tobón, M Arbeláez Referencia : Transplant Proc. 2013 May;45(4):1402-9. DOI (Digital Object Identifier) : 10.1016/j.transproceed.2012.10.053 PMID : 23726583 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0041-1345(12)01403-0 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3719 Survival of renal transplantation patients older than 60 years: a single-center experience [documento electrónico] / John Fredy Nieto Ríos, ; Lina Maria Serna Higuita, . - 2013.
Obra : Transplantation Proceedings
Idioma : Inglés (eng)
Resumen : Background: Elderly patients are the fastest growing population requiring renal replacement therapy. It has been stated that renal transplantation may be the best treatment option for these patients. However, it has been observed that older patients have a higher mortality rate than those who are younger. Yet the factors that determine post-transplantation outcomes in this population remain poorly defined. The aims of this study were to evaluate the graft and patient survival in kidney transplant recipients who are older than 60 years of age to identify relevant predictive factors. Methods: In this population-based retrospective cohort study of 201 kidney transplantations performed in elderly patients from January 2002 throughout June 2009, we estimated the 1-,3-,and 5-year patients and graft survival rates. We also evaluated the complications and the predictors of poor outcomes. Survival times were analyzed using the Kaplan–Meier method and survival differences assessed with Mantel-Cox log rank-test. We performed a Cox proportional hazards regression models to evaluate the impact of baseline and treatment characteristics on patient and graft survival. Results: Graft and patient survival rates at 1, 3, and 5 years were 76.4%, 71.3%, and 54.3%, and 78.2%, 73.8%, and 56.4%, respectively. Graft survival rates censored for patient death with a functioning graft were 93.1, 92.1, and 89%. Patient survival rates differed between diabetic and nondiabetic subjects at 1, 3 and 5 years (69.5% versus 83.6%; 59.8% versus 72.3%; 43.6% versus 65.7%; P = .008). On multivariate analysis, the factors associated with patients survival were diabetes mellitus (hazard ratio [HR] 2.058, 95% confidence interval [CI] 1.173–3.611, P = .012) and the 1-month serum creatinine value was > 1.6 mg/dL (HR 2.108 for each point increase, 95% CI 1.521–2.921, P = .000). Furthermore, there was an insignificant trend forward an association between active or past smoker and lower patient survival (HR 1.689, 95% CI 0.937–3.043, P = .08). The main causes of graft loss were patient death (79.5%). acute rejection (6.8%), and chronic allograft nephropathy (5.5%). Conclusion: Renal transplantation can be performed safely and with acceptable outcomes in elderly patients after appropriate clinical evaluation. The grafts show excellent survival albeit that deaths with a functional graft continue to be an important issue. Mención de responsabilidad : J R Rodelo, J F Nieto-Ríos, L M Serna-Higuita, J E Henao, A García, A C Reino, J C Tobón, M Arbeláez Referencia : Transplant Proc. 2013 May;45(4):1402-9. DOI (Digital Object Identifier) : 10.1016/j.transproceed.2012.10.053 PMID : 23726583 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0041-1345(12)01403-0 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3719 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000292 AC-2013-060 Archivo digital Producción Científica Artículos científicos Disponible Variante colapsante de la glomeruloesclerosis focal y segmentaria en niños / John Fredy Nieto Ríos ; Sandra Milena Brand ; Lina Maria Serna Higuita
Título : Variante colapsante de la glomeruloesclerosis focal y segmentaria en niños Otros títulos : Collapsing variant of focal segmental glomerulosclerosis in children Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Sandra Milena Brand, ; Lina Maria Serna Higuita, Fecha de publicación : 2013 Títulos uniformes : Iatreia Idioma : Español (spa) Palabras clave : Fallo Renal Crónico Glomeruloesclerosis Focal y Segmentaria Síndrome Nefrótico Resumen : La variedad colapsante de glomeruloesclerosis focal y segmentaria (GEFS) es una lesión renal que puede ser idiopática o estar asociada a diferentes factores; se caracteriza por colapso glomerular que lleva a un síndrome nefrótico corticorresistente y a falla renal crónica progresiva. Ha sido poco estudiada en niños y en ellos la mayoría de los casos son idiopáticos. Presentamos seis casos de esta variedad de GEFS en niños negativos para VIH, resistentes al tratamiento inmunosupresor; tres de ellos murieron. Mención de responsabilidad : John Fredy Nieto Ríos, Sandra Milena Brand, Lina María Serna Higuita, Luis Fernando Arias Referencia : Iatreia ; 26(4): 481-486, oct.-dic. 2013. Derechos de uso : CC BY-NC-ND En línea : https://revistas.udea.edu.co/index.php/iatreia/article/view/14323 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4526 Variante colapsante de la glomeruloesclerosis focal y segmentaria en niños = Collapsing variant of focal segmental glomerulosclerosis in children [documento electrónico] / John Fredy Nieto Ríos, ; Sandra Milena Brand, ; Lina Maria Serna Higuita, . - 2013.
Obra : Iatreia
Idioma : Español (spa)
Palabras clave : Fallo Renal Crónico Glomeruloesclerosis Focal y Segmentaria Síndrome Nefrótico Resumen : La variedad colapsante de glomeruloesclerosis focal y segmentaria (GEFS) es una lesión renal que puede ser idiopática o estar asociada a diferentes factores; se caracteriza por colapso glomerular que lleva a un síndrome nefrótico corticorresistente y a falla renal crónica progresiva. Ha sido poco estudiada en niños y en ellos la mayoría de los casos son idiopáticos. Presentamos seis casos de esta variedad de GEFS en niños negativos para VIH, resistentes al tratamiento inmunosupresor; tres de ellos murieron. Mención de responsabilidad : John Fredy Nieto Ríos, Sandra Milena Brand, Lina María Serna Higuita, Luis Fernando Arias Referencia : Iatreia ; 26(4): 481-486, oct.-dic. 2013. Derechos de uso : CC BY-NC-ND En línea : https://revistas.udea.edu.co/index.php/iatreia/article/view/14323 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4526 Reserva
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2013-112.pdfAdobe Acrobat PDF Histoplasmosis diseminada y síndrome hemofagocítico en dos pacientes trasplantados renales / John Fredy Nieto Ríos ; Arbey Aristizabal Álzate ; Catalina Ocampo Kohn ; Lina Maria Serna Higuita ; Gustavo Adolfo Zuluaga ValenciaPermalinkNefritis tubulointersticial y colangitis esclerosante asociadas a pancreatitis autoinmune / Arbey Aristizabal Álzate ; Carolina Muñoz Grajales ; Catalina Ocampo Kohn ; John Fredy Nieto Ríos ; Gustavo Adolfo Zuluaga ValenciaPermalinkInduction therapies in kidney transplantation: the experience of Hospital Pablo Tobon Uribe, Medellín, Colombia 2005-2010 / Catalina Ocampo Kohn ; Arbey Aristizabal Álzate ; John Fredy Nieto Ríos ; Harry Abadía Guzmán ; Walter Mario Ángel Jaramillo ; Carlos Ernesto Guzmán Luna ; Álvaro Mena Hurtado ; Juan José Vanegas Ruiz ; Catalina Vélez Echeverri ; Carlos Enrique Yepes Delgado ; Gustavo Adolfo Zuluaga ValenciaPermalink