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Autor Luis Vicente Syro Moreno
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Médico Neurocirujano, Hospital Pablo Tobón Uribe
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Double adenoma of the pituitary: a somatotroph adenoma colliding with a gonadotroph adenoma / Luis Vicente Syro Moreno
Título : Double adenoma of the pituitary: a somatotroph adenoma colliding with a gonadotroph adenoma Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2000 Títulos uniformes : Journal of Endocrinological Investigation Idioma : Inglés (eng) Palabras clave : Pituitary neoplasm pathology histology immunocytochemistry ultrastructure acromegaly somatotroph adenoma gonadotroph adenoma double adenomas collision tumors Resumen : Pituitary collision tumors are rare. They may create difficult diagnostic problems and their histogenesis is not clear. We report here an unusual case of a somatotroph adenoma colliding with a gonadotroph adenoma.The 64-year-old man had clinical acromegaly. His blood growth hormone level was elevated and magnetic resonance imaging demonstrated a pituitary tumor. The surgically removed sellar mass was investigated by histology, immunocytochemistry and electron microscopy. Morphologic study revealed a collision tumor; one was a somatotroph adenoma, the other a gonadotroph adenoma. Authors call attention to the difficulties in clinical, imaging and pathological diagnosis. Detailed morphologic studies are needed to establish the presence of two distinct tumors composed of two different cell types. Mención de responsabilidad : L. V. Syro, E. Horvath & Kalman Kovacs Referencia : J Endocrinol Invest. 2000 Jan;23(1):37-41. DOI (Digital Object Identifier) : 10.1007/BF03343674 PMID : 10698050 En línea : https://link.springer.com/article/10.1007/BF03343674 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4387 Double adenoma of the pituitary: a somatotroph adenoma colliding with a gonadotroph adenoma [documento electrónico] / Luis Vicente Syro Moreno, . - 2000.
Obra : Journal of Endocrinological Investigation
Idioma : Inglés (eng)
Palabras clave : Pituitary neoplasm pathology histology immunocytochemistry ultrastructure acromegaly somatotroph adenoma gonadotroph adenoma double adenomas collision tumors Resumen : Pituitary collision tumors are rare. They may create difficult diagnostic problems and their histogenesis is not clear. We report here an unusual case of a somatotroph adenoma colliding with a gonadotroph adenoma.The 64-year-old man had clinical acromegaly. His blood growth hormone level was elevated and magnetic resonance imaging demonstrated a pituitary tumor. The surgically removed sellar mass was investigated by histology, immunocytochemistry and electron microscopy. Morphologic study revealed a collision tumor; one was a somatotroph adenoma, the other a gonadotroph adenoma. Authors call attention to the difficulties in clinical, imaging and pathological diagnosis. Detailed morphologic studies are needed to establish the presence of two distinct tumors composed of two different cell types. Mención de responsabilidad : L. V. Syro, E. Horvath & Kalman Kovacs Referencia : J Endocrinol Invest. 2000 Jan;23(1):37-41. DOI (Digital Object Identifier) : 10.1007/BF03343674 PMID : 10698050 En línea : https://link.springer.com/article/10.1007/BF03343674 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4387 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000887 AC-2000-002 Archivo digital Producción Científica Artículos científicos Disponible Ultrastructural and immunoelectron microscopic study of three unusual plurihormonal pituitary adenomas / Luis Vicente Syro Moreno
Título : Ultrastructural and immunoelectron microscopic study of three unusual plurihormonal pituitary adenomas Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 1999 Títulos uniformes : Ultrastructural Pathology Idioma : Inglés (eng) Palabras clave : Human Immunoelectron Microscopy Pituitary Adenoma Plurihormonality Ultrastructure Resumen : Momomorphous pituitary adenomas expressing several hormones by immunocytochemistry are common, whereas adenomas displaying multiple immunoreactivities and consisting of more than one morphologic cell types are rare. Three such unusual pituitary adenomas, surgically removed from two patients with acromegaly and one patient with hyperprolactinemia, were investigated by histology, immunocytochemistry, transmission electron microscopy, as well as immunoelectron microscopy using double immunogold labeling. Immunocytochemistry revealed variable degrees of immunoreactivities for growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (beta-TSH), and alpha-subunit of glycoprotein hormones in all three tumors. The three adenomas consisted of phenotypically diverse cell populations as documented by transmission electron microscopy. In addition to monohormonal GH cells, immunoelectron microscopy demonstrated numerous cells colocalizing GH and PRL or GH and beta-TSH, and rarely PRL and beta-TSH in tumors of acromegalics. The adenoma causing hyperprolactinemia consisted chiefly of mammosomatotrophs colocalizing PRL and GH, whereas beta-TSH labeling was scant. The three tumors in the study were selected from a cluster of five plurimorphous plurihormonal adenomas received from the same locale where they accounted for an unprecedented 21% of adenomas producing GH and/or PRL. The enhanced susceptibility to develop plurimorphous adenomas of the acidophil cell line may have a genetic basis in the stable population the patients came from. Mención de responsabilidad : J F Molina, L R Espinoza Referencia : Ultrastruct Pathol. May-Jun 1999;23(3):141-8. DOI (Digital Object Identifier) : 10.1080/019131299281635 PMID : 10445280 En línea : https://www.tandfonline.com/doi/abs/10.1080/019131299281635 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4385 Ultrastructural and immunoelectron microscopic study of three unusual plurihormonal pituitary adenomas [documento electrónico] / Luis Vicente Syro Moreno, . - 1999.
Obra : Ultrastructural Pathology
Idioma : Inglés (eng)
Palabras clave : Human Immunoelectron Microscopy Pituitary Adenoma Plurihormonality Ultrastructure Resumen : Momomorphous pituitary adenomas expressing several hormones by immunocytochemistry are common, whereas adenomas displaying multiple immunoreactivities and consisting of more than one morphologic cell types are rare. Three such unusual pituitary adenomas, surgically removed from two patients with acromegaly and one patient with hyperprolactinemia, were investigated by histology, immunocytochemistry, transmission electron microscopy, as well as immunoelectron microscopy using double immunogold labeling. Immunocytochemistry revealed variable degrees of immunoreactivities for growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (beta-TSH), and alpha-subunit of glycoprotein hormones in all three tumors. The three adenomas consisted of phenotypically diverse cell populations as documented by transmission electron microscopy. In addition to monohormonal GH cells, immunoelectron microscopy demonstrated numerous cells colocalizing GH and PRL or GH and beta-TSH, and rarely PRL and beta-TSH in tumors of acromegalics. The adenoma causing hyperprolactinemia consisted chiefly of mammosomatotrophs colocalizing PRL and GH, whereas beta-TSH labeling was scant. The three tumors in the study were selected from a cluster of five plurimorphous plurihormonal adenomas received from the same locale where they accounted for an unprecedented 21% of adenomas producing GH and/or PRL. The enhanced susceptibility to develop plurimorphous adenomas of the acidophil cell line may have a genetic basis in the stable population the patients came from. Mención de responsabilidad : J F Molina, L R Espinoza Referencia : Ultrastruct Pathol. May-Jun 1999;23(3):141-8. DOI (Digital Object Identifier) : 10.1080/019131299281635 PMID : 10445280 En línea : https://www.tandfonline.com/doi/abs/10.1080/019131299281635 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4385 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000885 AC-1999-003 Archivo digital Producción Científica Artículos científicos Disponible