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Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease / Leonardo Fabio Moreno Gómez
Título : Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease Tipo de documento : documento electrónico Autores : Leonardo Fabio Moreno Gómez, Fecha de publicación : 2021 Títulos uniformes : Clinical Neurophysiology Idioma : Inglés (eng) Palabras clave : Alpha rhythm Electroencephalography Neuropsychological tests Parkinson’s Disease Theta rhythm Resumen : Objective: To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson's Disease (PD) non-demented patients. Methods: 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results: The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions: Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance: Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. Mención de responsabilidad : Alberto Jaramillo-Jimenez, Jazmin Ximena Suarez-Revelo, John Fredy Ochoa-Gomez, Jairo Alexander Carmona Arroyave, Yamile Bocanegra, Francisco Lopera, Omar Buriticá, David Antonio Pineda-Salazar, Leonardo Moreno Gómez, Carlos Andrés Tobón Quintero, Miguel Germán Borda, Laura Bonanni, Dominic H Ffytche, Kolbjørn Brønnick, Dag Aarsland Referencia : Clin Neurophysiol. 2021 Jan 13;132(3):756-764. DOI (Digital Object Identifier) : 10.1016/j.clinph.2021.01.001 PMID : 33571883 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(21)00003-1 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5758 Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease [documento electrónico] / Leonardo Fabio Moreno Gómez, . - 2021.
Obra : Clinical Neurophysiology
Idioma : Inglés (eng)
Palabras clave : Alpha rhythm Electroencephalography Neuropsychological tests Parkinson’s Disease Theta rhythm Resumen : Objective: To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson's Disease (PD) non-demented patients. Methods: 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results: The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions: Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance: Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. Mención de responsabilidad : Alberto Jaramillo-Jimenez, Jazmin Ximena Suarez-Revelo, John Fredy Ochoa-Gomez, Jairo Alexander Carmona Arroyave, Yamile Bocanegra, Francisco Lopera, Omar Buriticá, David Antonio Pineda-Salazar, Leonardo Moreno Gómez, Carlos Andrés Tobón Quintero, Miguel Germán Borda, Laura Bonanni, Dominic H Ffytche, Kolbjørn Brønnick, Dag Aarsland Referencia : Clin Neurophysiol. 2021 Jan 13;132(3):756-764. DOI (Digital Object Identifier) : 10.1016/j.clinph.2021.01.001 PMID : 33571883 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(21)00003-1 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5758 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001678 AC-2021-009 Archivo digital Producción Científica Artículos científicos Disponible Use of suggestive seizure manipulation methods in the investigation of patients with possible psychogenic nonepileptic seizures—An international ILAE survey / Lady Diana Ladino Malagón
Título : Use of suggestive seizure manipulation methods in the investigation of patients with possible psychogenic nonepileptic seizures—An international ILAE survey Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2021 Títulos uniformes : Epilepsia Open Idioma : Inglés (eng) Palabras clave : Psychogenic nonepileptic seizures (PNES) dissociative seizures provocation methods activation procedures electroencephalography suggestion diagnosis Resumen : Video-encephalographic (vEEG) seizure recordings make essential contributions to the differentiation of epilepsy and psychogenic nonepileptic seizures (PNES). The yield of vEEG examinations can be increased through suggestive seizure manipulation (SSM) (ie, activation/provocation/cessation procedures), but its use has raised ethical concerns. In preparation for guidelines on the investigation of patients with PNES, the ILAE PNES Task Force carried out an international survey to investigate practices of and opinions about SSM. An online questionnaire was developed by the ILAE PNES Task Force. Questions were asked at clinical unit or individual respondent level. All ILAE chapters were encouraged to send questionnaires to their members. The survey was open from July 1, 2019, to August 31, 2019. A total of 487 clinicians from 411 units across 94 countries responded. Some form of SSM was used in 296/411 units (72.0%). Over 90% reported the use of verbal suggestion, over 80% the use of activation procedures also capable of eliciting epileptic activity (hyperventilation or photic stimulation). Only 26.3% of units used techniques specifically intended to provoke PNES (eg, saline injection). Fewer than 10% of units had established protocols for SSM, only 20% of units required written patient consent, in 12.2% of units patients received explicitly false information to provoke seizures. Clinicians using SSM tended to perceive no ethical problems, whereas those not using SSM were likely to have ethical concerns about these methods. We conclude that the use of invasive nocebo techniques intended to provoke PNES in diagnostic settings has declined, but SSM is commonly combined with activation procedures also capable of eliciting epileptic activity. While research suggests that openness about the use of PNES-specific nocebo techniques does not reduce diagnostic yield, very few units have suggestion protocols or seek patient consent. This could be addressed through establishing consensus guidance for the practice of SSM. Mención de responsabilidad : Adrien Gras, Alistair Wardrope, Edouard Hirsch, Ali A Asadi Pooya, Rod Duncan, David Gigineishvili, Coraline Hingray, Kousuke Kanemoto, Lady Ladino, William Curt LaFrance, Aileen McGonigal, Chrisma Pretorius, Paola Valenti Hirsch, Pierre Vidailhet, Dong Zhou, Markus Reuber Referencia : Epilepsia Open. 2021 Sep;6(3):472-482. DOI (Digital Object Identifier) : 10.1002/epi4.12521 PMID : 34288577 Derechos de uso : CC BY En línea : https://onlinelibrary.wiley.com/doi/full/10.1002/epi4.12521 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5811 Use of suggestive seizure manipulation methods in the investigation of patients with possible psychogenic nonepileptic seizures—An international ILAE survey [documento electrónico] / Lady Diana Ladino Malagón, . - 2021.
Obra : Epilepsia Open
Idioma : Inglés (eng)
Palabras clave : Psychogenic nonepileptic seizures (PNES) dissociative seizures provocation methods activation procedures electroencephalography suggestion diagnosis Resumen : Video-encephalographic (vEEG) seizure recordings make essential contributions to the differentiation of epilepsy and psychogenic nonepileptic seizures (PNES). The yield of vEEG examinations can be increased through suggestive seizure manipulation (SSM) (ie, activation/provocation/cessation procedures), but its use has raised ethical concerns. In preparation for guidelines on the investigation of patients with PNES, the ILAE PNES Task Force carried out an international survey to investigate practices of and opinions about SSM. An online questionnaire was developed by the ILAE PNES Task Force. Questions were asked at clinical unit or individual respondent level. All ILAE chapters were encouraged to send questionnaires to their members. The survey was open from July 1, 2019, to August 31, 2019. A total of 487 clinicians from 411 units across 94 countries responded. Some form of SSM was used in 296/411 units (72.0%). Over 90% reported the use of verbal suggestion, over 80% the use of activation procedures also capable of eliciting epileptic activity (hyperventilation or photic stimulation). Only 26.3% of units used techniques specifically intended to provoke PNES (eg, saline injection). Fewer than 10% of units had established protocols for SSM, only 20% of units required written patient consent, in 12.2% of units patients received explicitly false information to provoke seizures. Clinicians using SSM tended to perceive no ethical problems, whereas those not using SSM were likely to have ethical concerns about these methods. We conclude that the use of invasive nocebo techniques intended to provoke PNES in diagnostic settings has declined, but SSM is commonly combined with activation procedures also capable of eliciting epileptic activity. While research suggests that openness about the use of PNES-specific nocebo techniques does not reduce diagnostic yield, very few units have suggestion protocols or seek patient consent. This could be addressed through establishing consensus guidance for the practice of SSM. Mención de responsabilidad : Adrien Gras, Alistair Wardrope, Edouard Hirsch, Ali A Asadi Pooya, Rod Duncan, David Gigineishvili, Coraline Hingray, Kousuke Kanemoto, Lady Ladino, William Curt LaFrance, Aileen McGonigal, Chrisma Pretorius, Paola Valenti Hirsch, Pierre Vidailhet, Dong Zhou, Markus Reuber Referencia : Epilepsia Open. 2021 Sep;6(3):472-482. DOI (Digital Object Identifier) : 10.1002/epi4.12521 PMID : 34288577 Derechos de uso : CC BY En línea : https://onlinelibrary.wiley.com/doi/full/10.1002/epi4.12521 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5811 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001745 AC-2021-061 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2021-061Adobe Acrobat PDF Forced normalization after turning off vagus nerve stimulation in Lennox-Gastaut syndrome / Lady Diana Ladino Malagón
Título : Forced normalization after turning off vagus nerve stimulation in Lennox-Gastaut syndrome Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2019 Títulos uniformes : Epilepsy & Behavior Case Reports Idioma : Inglés (eng) Palabras clave : ACTH adrenocorticotropic hormone ASD anti-seizure drug EEG electroencephalography FN forced normalization Forced normalization LGS Lennox Gastaut syndrome VNS vagus nerve stimulation Vagus nerve stimulation Resumen : Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped. The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy. The patient had multiple types of seizures including drop attacks, absences, and tonic-clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off. This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator. Mención de responsabilidad : Sydney Lee, Alyssa Denton, Lady Diana Ladino, Karen Waterhouse, Aleksander Vitali, Jose Francisco Tellez-Zenteno Referencia : Epilepsy Behav Case Rep. 2019 Jan 27;11:81-83 DOI (Digital Object Identifier) : 10.1016/j.ebcr.2019.01.004 PMID : 30788214 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S2213-3232(18)30177-4 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4260 Forced normalization after turning off vagus nerve stimulation in Lennox-Gastaut syndrome [documento electrónico] / Lady Diana Ladino Malagón, . - 2019.
Obra : Epilepsy & Behavior Case Reports
Idioma : Inglés (eng)
Palabras clave : ACTH adrenocorticotropic hormone ASD anti-seizure drug EEG electroencephalography FN forced normalization Forced normalization LGS Lennox Gastaut syndrome VNS vagus nerve stimulation Vagus nerve stimulation Resumen : Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped. The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy. The patient had multiple types of seizures including drop attacks, absences, and tonic-clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off. This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator. Mención de responsabilidad : Sydney Lee, Alyssa Denton, Lady Diana Ladino, Karen Waterhouse, Aleksander Vitali, Jose Francisco Tellez-Zenteno Referencia : Epilepsy Behav Case Rep. 2019 Jan 27;11:81-83 DOI (Digital Object Identifier) : 10.1016/j.ebcr.2019.01.004 PMID : 30788214 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S2213-3232(18)30177-4 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4260 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001239 AC-2019-028 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2019-028.pdfAdobe Acrobat PDF Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study / Leonardo Fabio Moreno Gómez
Título : Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study Tipo de documento : documento electrónico Autores : Leonardo Fabio Moreno Gómez, Fecha de publicación : 2019 Títulos uniformes : Future Neurology Idioma : Inglés (eng) Palabras clave : cognitive impairment electroencephalography executive functions functional connectivity Parkinson’s disease resting state Resumen : Objective: Parkinson’s disease (PD) is characterized by cognitive deficits. There is not clarity about electroencephalogram (EEG) connectivity related to the cognitive profile of patients. Our objective was to evaluate connectivity over resting EEG in nondemented PD. Methods: PD subjects with and without mild cognitive impairment (MCI) were assessed using coherence from resting EEG for local, intra and interhemispheric connectivity. Results: PD subjects without MCI (PD-nMCI) had lower intra and interhemispheric coherence in alpha2 compared with controls. PD with MCI (PD-MCI) showed higher intra and posterior interhemispheric coherence in alpha2 and beta1, respectively, in comparison to PD-nMCI. PD-MCI presented lower frontal coherence in beta frequencies compared with PD-nMCI. Conclusion: EEG coherence measures indicate distinct cortical activity in PD with and without MCI. Mención de responsabilidad : Jairo Alexander Carmona Arroyave, Carlos Andrés Tobón Quintero, Jasmín Jimena Suárez Revelo, John Fredy Ochoa Gómez, Yamile Bocanegra García, Leonardo Moreno Gómez & David Antonio Pineda Salazar DOI (Digital Object Identifier) : 10.2217/fnl-2018-0048 Derechos de uso : CC BY-NC-ND En línea : https://www.futuremedicine.com/doi/10.2217/fnl-2018-0048 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4293 Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study [documento electrónico] / Leonardo Fabio Moreno Gómez, . - 2019.
Obra : Future Neurology
Idioma : Inglés (eng)
Palabras clave : cognitive impairment electroencephalography executive functions functional connectivity Parkinson’s disease resting state Resumen : Objective: Parkinson’s disease (PD) is characterized by cognitive deficits. There is not clarity about electroencephalogram (EEG) connectivity related to the cognitive profile of patients. Our objective was to evaluate connectivity over resting EEG in nondemented PD. Methods: PD subjects with and without mild cognitive impairment (MCI) were assessed using coherence from resting EEG for local, intra and interhemispheric connectivity. Results: PD subjects without MCI (PD-nMCI) had lower intra and interhemispheric coherence in alpha2 compared with controls. PD with MCI (PD-MCI) showed higher intra and posterior interhemispheric coherence in alpha2 and beta1, respectively, in comparison to PD-nMCI. PD-MCI presented lower frontal coherence in beta frequencies compared with PD-nMCI. Conclusion: EEG coherence measures indicate distinct cortical activity in PD with and without MCI. Mención de responsabilidad : Jairo Alexander Carmona Arroyave, Carlos Andrés Tobón Quintero, Jasmín Jimena Suárez Revelo, John Fredy Ochoa Gómez, Yamile Bocanegra García, Leonardo Moreno Gómez & David Antonio Pineda Salazar DOI (Digital Object Identifier) : 10.2217/fnl-2018-0048 Derechos de uso : CC BY-NC-ND En línea : https://www.futuremedicine.com/doi/10.2217/fnl-2018-0048 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4293 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001273 AC-2019-063 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2019-063.pdfAdobe Acrobat PDF