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Malakoplakia after kidney transplantation: Case report and literature review / John Fredy Nieto Ríos ; Isabel Cristina Ramírez Sánchez ; Lina Maria Serna Higuita ; Alejandro Vélez Hoyos ; Federico Gaviria Gil
Título : Malakoplakia after kidney transplantation: Case report and literature review Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Isabel Cristina Ramírez Sánchez, ; Lina Maria Serna Higuita, ; Alejandro Vélez Hoyos, ; Federico Gaviria Gil, Fecha de publicación : 2017 Títulos uniformes : Transplant Infectious Disease Idioma : Inglés (eng) Palabras clave : Escherichia coli immunosuppression kidney transplantation malakoplakia urinary tract infection Resumen : Malakoplakia is a granulomatous disease associated with an infectious etiology, usually involving the urinary tract. It reveals itself as a recurrent urinary tract infection (r‐UTI), and in some cases, it is associated with impairment of renal function. Immunosuppression is one of its main associated factors, and it has been increasingly described in patients with solid organ transplantation (SOT), mainly kidney transplantation. Macroscopically, it can form masses and sometimes it may be confused with neoplasia, which is why histological findings are fundamental for the diagnosis. Here, we present a case of bladder malakoplakia, manifested by r‐UTI from Escherichia coli in a patient with renal transplantation, refractory to long‐term antibiotic treatment and reduction in immunosuppression, which resolved after surgical management. We also summarize the clinical characteristics of malakoplakia and compare them with previous reports in the literature on SOT. Mención de responsabilidad : John Fredy Nieto-Ríos, Isabel Ramírez, Mónica Zuluaga-Quintero, Lina María Serna-Higuita, Federico Gaviria-Gil, Alejandro Velez-Hoyos Referencia : Transpl Infect Dis. 2017 Oct;19(5). DOI (Digital Object Identifier) : 10.1111/tid.12731 PMID : 28561517 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/tid.12731 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4065 Malakoplakia after kidney transplantation: Case report and literature review [documento electrónico] / John Fredy Nieto Ríos, ; Isabel Cristina Ramírez Sánchez, ; Lina Maria Serna Higuita, ; Alejandro Vélez Hoyos, ; Federico Gaviria Gil, . - 2017.
Obra : Transplant Infectious Disease
Idioma : Inglés (eng)
Palabras clave : Escherichia coli immunosuppression kidney transplantation malakoplakia urinary tract infection Resumen : Malakoplakia is a granulomatous disease associated with an infectious etiology, usually involving the urinary tract. It reveals itself as a recurrent urinary tract infection (r‐UTI), and in some cases, it is associated with impairment of renal function. Immunosuppression is one of its main associated factors, and it has been increasingly described in patients with solid organ transplantation (SOT), mainly kidney transplantation. Macroscopically, it can form masses and sometimes it may be confused with neoplasia, which is why histological findings are fundamental for the diagnosis. Here, we present a case of bladder malakoplakia, manifested by r‐UTI from Escherichia coli in a patient with renal transplantation, refractory to long‐term antibiotic treatment and reduction in immunosuppression, which resolved after surgical management. We also summarize the clinical characteristics of malakoplakia and compare them with previous reports in the literature on SOT. Mención de responsabilidad : John Fredy Nieto-Ríos, Isabel Ramírez, Mónica Zuluaga-Quintero, Lina María Serna-Higuita, Federico Gaviria-Gil, Alejandro Velez-Hoyos Referencia : Transpl Infect Dis. 2017 Oct;19(5). DOI (Digital Object Identifier) : 10.1111/tid.12731 PMID : 28561517 En línea : https://onlinelibrary.wiley.com/doi/abs/10.1111/tid.12731 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4065 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000667 AC-2017-056 Archivo digital Producción Científica Artículos científicos Disponible Urinary tract infection leading to hospital admission during the first year after kidney transplantation: A retrospective cohort study / Fabián Alberto Jaimes Barragán
Título : Urinary tract infection leading to hospital admission during the first year after kidney transplantation: A retrospective cohort study Tipo de documento : documento electrónico Autores : Fabián Alberto Jaimes Barragán, Fecha de publicación : 2016 Títulos uniformes : Transplantation Reports Idioma : Inglés (eng) Palabras clave : CKD Chronic kidney disease CKF Chronic kidney failure ESRD end stage renal disease HD hemodialysis KTR kidney transplant recipients MDR Multidrug resistant MMF mycophenolate mofetil mTOR mammalian target of rapamycin PD peritoneal dialysis RRT renal replacement therapy UTI Urinary tract infection TMP/SMX Trimethoprim-sulfamethoxazole XDR Extensively drug-resistant Resumen : Introduction: Urinary tract infection (UTI) is the most common infectious problem in kidney transplant recipients (KTR). It has been associated with risk factors inherent to the transplant and it could negatively affect clinical outcomes. The aim of this study was to describe demographic, clinical and microbiological characteristics of patients with UTI. Methods: We underwent a retrospective study reviewing the database of kidney transplants patients in a national reference center in Colombia. We included patients admitted for inpatient treatment related to urinary tract infection in the first year after transplantation. Results: We describe clinical information from 65 patients, the mean age was 46 years, the most common comorbidity was hypertension (n=48/62, 77.4%) followed by diabetes mellitus (n=11/62, 17.7%); 77% (n=50/65) of the infections were diagnosed in the first 6 months after transplant and 70% (n=45/65) had pyelonephritis. Acute dysfunction of the graft was the most common complication in 59% (n=33/56) of cases. The most common etiological agent described was E. coli in 67% (n=37/55) of patients followed by Klebsiella pneumoniae (n=13/55). Bacteremia was present in 25% of cases. Infection with extended-spectrum betalactamases producing bacteria was present in 42% (n=18/42) of our isolations and multidrug resistance was documented in 39% (n=21/54) of isolates. Conclusion: Most UTI leading to hospitalization in KTR occur in the first six months. Pyelonephritis explains the majority of clinical diagnosis. The rate of blood stream infections and multidrug resistance bacteria is high, justifying an empiric broad-spectrum antibiotic treatment. Mención de responsabilidad : Santiago Giraldo-Ramírez, Oscar Emilio Díaz-Portilla, Andrés Felipe Miranda-Arboleda, Jorge Henao-Sierra, Lina María Echeverri-Toro, Fabian Jaimes DOI (Digital Object Identifier) : 10.1016/j.tpr.2016.09.001 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S2451959616300154 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4616 Urinary tract infection leading to hospital admission during the first year after kidney transplantation: A retrospective cohort study [documento electrónico] / Fabián Alberto Jaimes Barragán, . - 2016.
Obra : Transplantation Reports
Idioma : Inglés (eng)
Palabras clave : CKD Chronic kidney disease CKF Chronic kidney failure ESRD end stage renal disease HD hemodialysis KTR kidney transplant recipients MDR Multidrug resistant MMF mycophenolate mofetil mTOR mammalian target of rapamycin PD peritoneal dialysis RRT renal replacement therapy UTI Urinary tract infection TMP/SMX Trimethoprim-sulfamethoxazole XDR Extensively drug-resistant Resumen : Introduction: Urinary tract infection (UTI) is the most common infectious problem in kidney transplant recipients (KTR). It has been associated with risk factors inherent to the transplant and it could negatively affect clinical outcomes. The aim of this study was to describe demographic, clinical and microbiological characteristics of patients with UTI. Methods: We underwent a retrospective study reviewing the database of kidney transplants patients in a national reference center in Colombia. We included patients admitted for inpatient treatment related to urinary tract infection in the first year after transplantation. Results: We describe clinical information from 65 patients, the mean age was 46 years, the most common comorbidity was hypertension (n=48/62, 77.4%) followed by diabetes mellitus (n=11/62, 17.7%); 77% (n=50/65) of the infections were diagnosed in the first 6 months after transplant and 70% (n=45/65) had pyelonephritis. Acute dysfunction of the graft was the most common complication in 59% (n=33/56) of cases. The most common etiological agent described was E. coli in 67% (n=37/55) of patients followed by Klebsiella pneumoniae (n=13/55). Bacteremia was present in 25% of cases. Infection with extended-spectrum betalactamases producing bacteria was present in 42% (n=18/42) of our isolations and multidrug resistance was documented in 39% (n=21/54) of isolates. Conclusion: Most UTI leading to hospitalization in KTR occur in the first six months. Pyelonephritis explains the majority of clinical diagnosis. The rate of blood stream infections and multidrug resistance bacteria is high, justifying an empiric broad-spectrum antibiotic treatment. Mención de responsabilidad : Santiago Giraldo-Ramírez, Oscar Emilio Díaz-Portilla, Andrés Felipe Miranda-Arboleda, Jorge Henao-Sierra, Lina María Echeverri-Toro, Fabian Jaimes DOI (Digital Object Identifier) : 10.1016/j.tpr.2016.09.001 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S2451959616300154 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4616 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001114 AC-2016-095 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2016-095.pdfAdobe Acrobat PDF Vesicoureteral reflux management with subureteral injection of polydimethylsiloxane in cases of recurrent pyelonephritis in transplanted kidneys / Arbey Aristizabal Álzate ; Carlos Enrique Yepes Delgado ; Lina Maria Serna Higuita ; John Fredy Nieto Ríos ; Catalina Ocampo Kohn ; Carlos Alberto Uribe Trujillo ; Gustavo Adolfo Zuluaga Valencia ; Matilde Henao Velásquez
Título : Vesicoureteral reflux management with subureteral injection of polydimethylsiloxane in cases of recurrent pyelonephritis in transplanted kidneys Tipo de documento : documento electrónico Autores : Arbey Aristizabal Álzate, ; Carlos Enrique Yepes Delgado, ; Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Carlos Alberto Uribe Trujillo, ; Gustavo Adolfo Zuluaga Valencia, ; Matilde Henao Velásquez, Fecha de publicación : 2016 Títulos uniformes : World Journal of Nephrology and Urology Idioma : Inglés (eng) Palabras clave : Renal transplantation Pyelonephritis Urinary tract infection Vesicoureteral reflux Endoscopic treatment Resumen : Background: Kidney graft pyelonephritis is a common complication after renal transplantation, often prompted by vesicoureteral reflux (VUR). An effective and minimally invasive strategy for managing reflux that allows a decrease in the risk of recurrent pyelonephritis is desirable. The aim of this study was to describe our experience with an endoscopic treatment with subureteral injection of polydimethylsiloxane for the treatment of recurrent pyelonephritis of renal grafts secondary to VUR. Methods: Between 2011 and 2016, 17 subureteral polydimethylsiloxane injection procedures were performed. Patient monitoring was done by outpatient consultation and medical record review. The number of pyelonephritis events before and after the procedure and its safety were compared. Results: Forty-six infection episodes occurred before the procedure (2.71 infections/patient/year) and 10 infection episodes occurred after the procedure (0.59 infections/patient/year), representing a 78.3% reduction of infections/patient/year. The procedure was well tolerated and safe, with no resultant obstructive complications or changes in renal function and no long-distance migration of the bulking agent detected by monitoring.Conclusion: Consistent endoscopic treatment with subureteral injection of the bulking agent polydimethylsiloxane to manage VUR in cases of recurrent pyelonephritis of kidney grafts is a non-invasive treatment option with a good success rate and safety profile. Mención de responsabilidad : Arbey Aristizabal-Alzate, Guillermo Salazar-Villa, Carlos Yepes-Delgado, Lina Maria Serna-Higuita, John Fredy Nieto-Rios, Catalina Ocampo-Kohn, Carlos Uribe-Trujillo, Matilde Henao-Velasquez, Gustavo Zuluaga-Valencia Referencia : World J Nephrol Urol. 2016;5(4):71-8. DOI (Digital Object Identifier) : 10.14740/wjnu296w Derechos de uso : CC BY-NC En línea : https://www.wjnu.org/index.php/WJNU/article/view/296 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4013 Vesicoureteral reflux management with subureteral injection of polydimethylsiloxane in cases of recurrent pyelonephritis in transplanted kidneys [documento electrónico] / Arbey Aristizabal Álzate, ; Carlos Enrique Yepes Delgado, ; Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Carlos Alberto Uribe Trujillo, ; Gustavo Adolfo Zuluaga Valencia, ; Matilde Henao Velásquez, . - 2016.
Obra : World Journal of Nephrology and Urology
Idioma : Inglés (eng)
Palabras clave : Renal transplantation Pyelonephritis Urinary tract infection Vesicoureteral reflux Endoscopic treatment Resumen : Background: Kidney graft pyelonephritis is a common complication after renal transplantation, often prompted by vesicoureteral reflux (VUR). An effective and minimally invasive strategy for managing reflux that allows a decrease in the risk of recurrent pyelonephritis is desirable. The aim of this study was to describe our experience with an endoscopic treatment with subureteral injection of polydimethylsiloxane for the treatment of recurrent pyelonephritis of renal grafts secondary to VUR. Methods: Between 2011 and 2016, 17 subureteral polydimethylsiloxane injection procedures were performed. Patient monitoring was done by outpatient consultation and medical record review. The number of pyelonephritis events before and after the procedure and its safety were compared. Results: Forty-six infection episodes occurred before the procedure (2.71 infections/patient/year) and 10 infection episodes occurred after the procedure (0.59 infections/patient/year), representing a 78.3% reduction of infections/patient/year. The procedure was well tolerated and safe, with no resultant obstructive complications or changes in renal function and no long-distance migration of the bulking agent detected by monitoring.Conclusion: Consistent endoscopic treatment with subureteral injection of the bulking agent polydimethylsiloxane to manage VUR in cases of recurrent pyelonephritis of kidney grafts is a non-invasive treatment option with a good success rate and safety profile. Mención de responsabilidad : Arbey Aristizabal-Alzate, Guillermo Salazar-Villa, Carlos Yepes-Delgado, Lina Maria Serna-Higuita, John Fredy Nieto-Rios, Catalina Ocampo-Kohn, Carlos Uribe-Trujillo, Matilde Henao-Velasquez, Gustavo Zuluaga-Valencia Referencia : World J Nephrol Urol. 2016;5(4):71-8. DOI (Digital Object Identifier) : 10.14740/wjnu296w Derechos de uso : CC BY-NC En línea : https://www.wjnu.org/index.php/WJNU/article/view/296 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4013 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000608 AC-2016-083 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2016-083.pdfAdobe Acrobat PDF Profile resistance of pathogens causing urinary tract infection in the pediatric population, and antibiotic treatment response, at a University Hospital 2010-2011 / Catalina Vélez Echeverri ; Lina Maria Serna Higuita ; Ana María Bedoya Londoño ; Margarita María Suárez Galvis ; Catalina Hincapié Ocampo ; Adriana Isabel Henao López ; Diana C. Ortíz M. ; Juan José Vanegas Ruiz ; John Jairo Zuleta Tobón ; David Andrés Espinal Botero
Título : Profile resistance of pathogens causing urinary tract infection in the pediatric population, and antibiotic treatment response, at a University Hospital 2010-2011 Otros títulos : Perfil de resistencia de los patógenos causantes de infección urinaria en la población pediátrica y respuesta al tratamiento antibiótico, en un hospital universitario 2010-2011 Tipo de documento : documento electrónico Autores : Catalina Vélez Echeverri, ; Lina Maria Serna Higuita, ; Ana María Bedoya Londoño, ; Margarita María Suárez Galvis, ; Catalina Hincapié Ocampo, ; Adriana Isabel Henao López, ; Diana C. Ortíz M., ; Juan José Vanegas Ruiz, ; John Jairo Zuleta Tobón, ; David Andrés Espinal Botero, Fecha de publicación : 2014 Títulos uniformes : Colombia Médica Idioma : Inglés (eng) Palabras clave : Urinary tract infection drug resistance bacterial Escherichia coli Resumen : Introduction: Urinary tract infection (UTI) is one of the most common bacterial infections in childhood and causes acute and chronic morbidity and long-term hypertension and chronic kidney disease. Objectives: To describe the demographic characteristics, infectious agents, patterns of antibiotic resistance, etiologic agent and profile of susceptibility and response to empirical treatment of UTI in a pediatric population. Methods: This is a descriptive, retrospective study. Results: Included in the study were 144 patients, 1:2.06 male to female ratio. The most common symptom was fever (79.9%) and 31.3% had a history of previous UTI. 72.0% of the patients had positive urine leukocyte count (>5 per field), urine gram was positive in 85.0% of samples and gram negative bacilli accounted for 77.8% for the total pathogens isolated. The most frequent uropathogens isolated were Escherichia coli and Klebsiella pneumoniae. Our E.coli isolates had a susceptibility rate higher than 90% to most of the antibiotics used, but a resistance rate of 42.6% to TMP SMX and 45.5% to ampicillin sulbactam. 6.3% of E. coliwas extended-spectrum beta-lactamases producer strains. The most frequent empirical antibiotic used was amikacin, which was used in 66.0% of the patients. 17 of 90 patients who underwent voiding cistouretrography (VCUG) had vesicoureteral reflux. Conclusion: This study revealed that E. coli was the most frequent pathogen of community acquired UTI. We found that E. coli and other uropathogens had a high resistance rate against TMP SMX and ampicillin sulbactam. In order to ensure a successful empirical treatment, protocols should be based on local epidemiology and susceptibility rates. Mención de responsabilidad : Catalina Vélez Echeverri, Lina María Serna-Higuita, Ana Katherina Serrano, Carolina Ochoa-García, Luisa Rojas Rosas, Ana María Bedoya, Margarita Suárez, Catalina Hincapié, Adriana Henao, Diana Ortiz, Juan José Vanegas, John Jairo Zuleta, David Espinal Referencia : Colomb Med (Cali). 2014 Mar 30;45(1):39-44. DOI (Digital Object Identifier) : 10.25100/cm.v45i1.1318 PMID : 24970958 Derechos de uso : CC BY-NC-ND En línea : https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1318 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5721 Profile resistance of pathogens causing urinary tract infection in the pediatric population, and antibiotic treatment response, at a University Hospital 2010-2011 = Perfil de resistencia de los patógenos causantes de infección urinaria en la población pediátrica y respuesta al tratamiento antibiótico, en un hospital universitario 2010-2011 [documento electrónico] / Catalina Vélez Echeverri, ; Lina Maria Serna Higuita, ; Ana María Bedoya Londoño, ; Margarita María Suárez Galvis, ; Catalina Hincapié Ocampo, ; Adriana Isabel Henao López, ; Diana C. Ortíz M., ; Juan José Vanegas Ruiz, ; John Jairo Zuleta Tobón, ; David Andrés Espinal Botero, . - 2014.
Obra : Colombia Médica
Idioma : Inglés (eng)
Palabras clave : Urinary tract infection drug resistance bacterial Escherichia coli Resumen : Introduction: Urinary tract infection (UTI) is one of the most common bacterial infections in childhood and causes acute and chronic morbidity and long-term hypertension and chronic kidney disease. Objectives: To describe the demographic characteristics, infectious agents, patterns of antibiotic resistance, etiologic agent and profile of susceptibility and response to empirical treatment of UTI in a pediatric population. Methods: This is a descriptive, retrospective study. Results: Included in the study were 144 patients, 1:2.06 male to female ratio. The most common symptom was fever (79.9%) and 31.3% had a history of previous UTI. 72.0% of the patients had positive urine leukocyte count (>5 per field), urine gram was positive in 85.0% of samples and gram negative bacilli accounted for 77.8% for the total pathogens isolated. The most frequent uropathogens isolated were Escherichia coli and Klebsiella pneumoniae. Our E.coli isolates had a susceptibility rate higher than 90% to most of the antibiotics used, but a resistance rate of 42.6% to TMP SMX and 45.5% to ampicillin sulbactam. 6.3% of E. coliwas extended-spectrum beta-lactamases producer strains. The most frequent empirical antibiotic used was amikacin, which was used in 66.0% of the patients. 17 of 90 patients who underwent voiding cistouretrography (VCUG) had vesicoureteral reflux. Conclusion: This study revealed that E. coli was the most frequent pathogen of community acquired UTI. We found that E. coli and other uropathogens had a high resistance rate against TMP SMX and ampicillin sulbactam. In order to ensure a successful empirical treatment, protocols should be based on local epidemiology and susceptibility rates. Mención de responsabilidad : Catalina Vélez Echeverri, Lina María Serna-Higuita, Ana Katherina Serrano, Carolina Ochoa-García, Luisa Rojas Rosas, Ana María Bedoya, Margarita Suárez, Catalina Hincapié, Adriana Henao, Diana Ortiz, Juan José Vanegas, John Jairo Zuleta, David Espinal Referencia : Colomb Med (Cali). 2014 Mar 30;45(1):39-44. DOI (Digital Object Identifier) : 10.25100/cm.v45i1.1318 PMID : 24970958 Derechos de uso : CC BY-NC-ND En línea : https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1318 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5721 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001683 AC-2014-158 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2014-158Adobe Acrobat PDF