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Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study / Leonardo Fabio Moreno Gómez
Título : Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study Tipo de documento : documento electrónico Autores : Leonardo Fabio Moreno Gómez, Fecha de publicación : 2019 Títulos uniformes : Future Neurology Idioma : Inglés (eng) Palabras clave : cognitive impairment electroencephalography executive functions functional connectivity Parkinson’s disease resting state Resumen : Objective: Parkinson’s disease (PD) is characterized by cognitive deficits. There is not clarity about electroencephalogram (EEG) connectivity related to the cognitive profile of patients. Our objective was to evaluate connectivity over resting EEG in nondemented PD. Methods: PD subjects with and without mild cognitive impairment (MCI) were assessed using coherence from resting EEG for local, intra and interhemispheric connectivity. Results: PD subjects without MCI (PD-nMCI) had lower intra and interhemispheric coherence in alpha2 compared with controls. PD with MCI (PD-MCI) showed higher intra and posterior interhemispheric coherence in alpha2 and beta1, respectively, in comparison to PD-nMCI. PD-MCI presented lower frontal coherence in beta frequencies compared with PD-nMCI. Conclusion: EEG coherence measures indicate distinct cortical activity in PD with and without MCI. Mención de responsabilidad : Jairo Alexander Carmona Arroyave, Carlos Andrés Tobón Quintero, Jasmín Jimena Suárez Revelo, John Fredy Ochoa Gómez, Yamile Bocanegra García, Leonardo Moreno Gómez & David Antonio Pineda Salazar DOI (Digital Object Identifier) : 10.2217/fnl-2018-0048 Derechos de uso : CC BY-NC-ND En línea : https://www.futuremedicine.com/doi/10.2217/fnl-2018-0048 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4293 Resting functional connectivity and mild cognitive impairment in Parkinson's disease. An electroencephalogram study [documento electrónico] / Leonardo Fabio Moreno Gómez, . - 2019.
Obra : Future Neurology
Idioma : Inglés (eng)
Palabras clave : cognitive impairment electroencephalography executive functions functional connectivity Parkinson’s disease resting state Resumen : Objective: Parkinson’s disease (PD) is characterized by cognitive deficits. There is not clarity about electroencephalogram (EEG) connectivity related to the cognitive profile of patients. Our objective was to evaluate connectivity over resting EEG in nondemented PD. Methods: PD subjects with and without mild cognitive impairment (MCI) were assessed using coherence from resting EEG for local, intra and interhemispheric connectivity. Results: PD subjects without MCI (PD-nMCI) had lower intra and interhemispheric coherence in alpha2 compared with controls. PD with MCI (PD-MCI) showed higher intra and posterior interhemispheric coherence in alpha2 and beta1, respectively, in comparison to PD-nMCI. PD-MCI presented lower frontal coherence in beta frequencies compared with PD-nMCI. Conclusion: EEG coherence measures indicate distinct cortical activity in PD with and without MCI. Mención de responsabilidad : Jairo Alexander Carmona Arroyave, Carlos Andrés Tobón Quintero, Jasmín Jimena Suárez Revelo, John Fredy Ochoa Gómez, Yamile Bocanegra García, Leonardo Moreno Gómez & David Antonio Pineda Salazar DOI (Digital Object Identifier) : 10.2217/fnl-2018-0048 Derechos de uso : CC BY-NC-ND En línea : https://www.futuremedicine.com/doi/10.2217/fnl-2018-0048 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4293 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001273 AC-2019-063 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2019-063.pdfAdobe Acrobat PDF Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences / Omar Fredy Buriticá Henao
Título : Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences Tipo de documento : documento electrónico Autores : Omar Fredy Buriticá Henao, Fecha de publicación : 2015 Títulos uniformes : Cortex Idioma : Inglés (eng) Palabras clave : Parkinson's disease syntax action verbs action semantics object semantics executive functions mild cognitive impairment Resumen : Several studies have recently shown that basal ganglia (BG) deterioration leads to distinctive impairments in the domains of syntax, action verbs, and action semantics. In particular, such disruptions have been repeatedly observed in Parkinson's disease (PD) patients. However, it remains unclear whether these deficits are language-specific and whether they are equally dissociable from other reported disturbances –viz., processing of object semantics. To address these issues, we administered linguistic, semantic, and executive function (EFs) tasks to two groups of non-demented PD patients, with and without mild cognitive impairment (PD-MCI and PD-nMCI, respectively). We compared these two groups with each other and with matched samples of healthy controls. Our results showed that PD patients exhibited linguistic and semantic deficits even in the absence of MCI. However, not all domains were equally related to EFs and MCI across samples. Whereas EFs predicted disturbances of syntax and object semantics in both PD-nMCI and PD-MCI, they had no impact on action-verb and action-semantic impairments in either group. Critically, patients showed disruptions of action-verb production and action semantics in the absence of MCI and without any executive influence, suggesting a sui generis deficit present since early stages of the disease. These findings indicate that varied language domains are differentially related to the BG, contradicting popular approaches to neurolinguistics. Mención de responsabilidad : Yamile Bocanegra, Adolfo M García, David Pineda, Omar Buriticá, Andrés Villegas, Francisco Lopera, Diana Gómez, Catalina Gómez-Arias, Juan F Cardona, Natalia Trujillo, Agustín Ibáñez Referencia : Cortex. 2015 Aug;69:237-54. DOI (Digital Object Identifier) : 10.1016/j.cortex.2015.05.022 PMID : 26103601 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0010945215001811#abs0010 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3895 Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences [documento electrónico] / Omar Fredy Buriticá Henao, . - 2015.
Obra : Cortex
Idioma : Inglés (eng)
Palabras clave : Parkinson's disease syntax action verbs action semantics object semantics executive functions mild cognitive impairment Resumen : Several studies have recently shown that basal ganglia (BG) deterioration leads to distinctive impairments in the domains of syntax, action verbs, and action semantics. In particular, such disruptions have been repeatedly observed in Parkinson's disease (PD) patients. However, it remains unclear whether these deficits are language-specific and whether they are equally dissociable from other reported disturbances –viz., processing of object semantics. To address these issues, we administered linguistic, semantic, and executive function (EFs) tasks to two groups of non-demented PD patients, with and without mild cognitive impairment (PD-MCI and PD-nMCI, respectively). We compared these two groups with each other and with matched samples of healthy controls. Our results showed that PD patients exhibited linguistic and semantic deficits even in the absence of MCI. However, not all domains were equally related to EFs and MCI across samples. Whereas EFs predicted disturbances of syntax and object semantics in both PD-nMCI and PD-MCI, they had no impact on action-verb and action-semantic impairments in either group. Critically, patients showed disruptions of action-verb production and action semantics in the absence of MCI and without any executive influence, suggesting a sui generis deficit present since early stages of the disease. These findings indicate that varied language domains are differentially related to the BG, contradicting popular approaches to neurolinguistics. Mención de responsabilidad : Yamile Bocanegra, Adolfo M García, David Pineda, Omar Buriticá, Andrés Villegas, Francisco Lopera, Diana Gómez, Catalina Gómez-Arias, Juan F Cardona, Natalia Trujillo, Agustín Ibáñez Referencia : Cortex. 2015 Aug;69:237-54. DOI (Digital Object Identifier) : 10.1016/j.cortex.2015.05.022 PMID : 26103601 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0010945215001811#abs0010 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3895 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000475 AC-2015-028 Archivo digital Producción Científica Artículos científicos Disponible