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Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia / Carolina Jaramillo Arango ; Carlos Enrique Yepes Delgado ; Verónica Abad Londoño    

Público ISBD Título : Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia Tipo de documento : documento electrónico Autores : Carolina Jaramillo Arango, ; Carlos Enrique Yepes Delgado, ; Verónica Abad Londoño, Fecha de publicación : 2018 Títulos uniformes : Endocrinology and Metabolism International Journal Idioma : Inglés (eng) Palabras clave : celiac disease  type 1 diabetes  tissue transglutaminase autoantibody  autoimmunity  and prevalence Resumen : Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or thyroid comorbidity. Objective: To assess the prevalence of celiac autoimmunity in children and adolescents diagnosed with type 1 diabetes mellitus and to identify the clinical profile of patients with celiac autoimmunity. Methods: One hundred patients with type 1 diabetes mellitus under 18 years, who consulted the department of pediatric endocrinology at Hospital Pablo Tobón Uribe – Medellin, between May and December 2015, were included. The concentration of antibodies, anti-tissue transglutaminase IgA, and total immunoglobulin A were measured in all patients; also a survey of signs and symptoms of celiac disease was applied. Results: Patients were aged between 3 and 17 years. Four had celiac autoimmunity evidenced by positive anti-tissue transglutaminase IgA. The clinical profile of patients with celiac autoimmunity was patient Mención de responsabilidad : Carolina Jaramillo Arango, Yúrika López-Alarcón, Alejandro Marín-Agudelo, Carlos Yepes Delgado, Verónica Abad-Londoño DOI (Digital Object Identifier) : 10.15406/emij.2018.06.00172 Derechos de uso : CC BY-NC En línea : https://medcraveonline.com/EMIJ/prevalence-of-celiac-autoimmunity-in-children-an [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4734 Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia [documento electrónico] / Carolina Jaramillo Arango, ; Carlos Enrique Yepes Delgado, ; Verónica Abad Londoño,  . - 2018. Obra : Endocrinology and Metabolism International Journal Idioma : Inglés (eng) Palabras clave : celiac disease  type 1 diabetes  tissue transglutaminase autoantibody  autoimmunity  and prevalence Resumen : Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or thyroid comorbidity. Objective: To assess the prevalence of celiac autoimmunity in children and adolescents diagnosed with type 1 diabetes mellitus and to identify the clinical profile of patients with celiac autoimmunity. Methods: One hundred patients with type 1 diabetes mellitus under 18 years, who consulted the department of pediatric endocrinology at Hospital Pablo Tobón Uribe – Medellin, between May and December 2015, were included. The concentration of antibodies, anti-tissue transglutaminase IgA, and total immunoglobulin A were measured in all patients; also a survey of signs and symptoms of celiac disease was applied. Results: Patients were aged between 3 and 17 years. Four had celiac autoimmunity evidenced by positive anti-tissue transglutaminase IgA. The clinical profile of patients with celiac autoimmunity was patient Mención de responsabilidad : Carolina Jaramillo Arango, Yúrika López-Alarcón, Alejandro Marín-Agudelo, Carlos Yepes Delgado, Verónica Abad-Londoño DOI (Digital Object Identifier) : 10.15406/emij.2018.06.00172 Derechos de uso : CC BY-NC En línea : https://medcraveonline.com/EMIJ/prevalence-of-celiac-autoimmunity-in-children-an [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4734

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Clinical and immunological characteristics of type 1 diabetes mellitus in a northwestern Colombian population / Verónica Abad Londoño ; Alejandro Daniel Velásquez Urzola  

Público ISBD Título : Clinical and immunological characteristics of type 1 diabetes mellitus in a northwestern Colombian population Tipo de documento : documento electrónico Autores : Verónica Abad Londoño, ; Alejandro Daniel Velásquez Urzola, Fecha de publicación : 2006 Títulos uniformes : Diabetes Research and Clinical Practice Idioma : Inglés (eng) Palabras clave : Type 1 diabetes  GADA  IA-2A  IAA  Colombia Resumen : We underwent a project aimed to define the clinical and immunological characteristics of type 1 diabetes (T1D) in a Colombian population. This was a multicenter and cross-sectional study. Patients were systematically interviewed and their medical records reviewed, using a questionnaire that sought information about demographic, clinical and immunological characteristics. Glutamic acid decarboxylase antibodies (GADA), tyrosine phosphatase antibodies (IA-2A) and insulin antibodies (IAA) were examined by radioimmunoassay. There were 107 patients with T1D. Male:female ratio was 1:1. Half of the patients developed diabetes ketoacidosis at onset. GADA, IA-2A, and IAA were detected in 45%, 40%, and 69% of the cases, respectively. GADA positive patients were older and had a less duration of disease than patients without these autoantibodies ( p  Mención de responsabilidad : G J Tobon, A Arango, V Abad, J García, H Cuervo, A Velásquez, I D Angel, P Vega, A Abad, J-M Anaya Referencia : Diabetes Res Clin Pract. 2006 May;72(2):170-5. DOI (Digital Object Identifier) : 10.1016/j.diabres.2005.10.016 PMID : 16325957 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0168822705004225 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4420 Clinical and immunological characteristics of type 1 diabetes mellitus in a northwestern Colombian population [documento electrónico] / Verónica Abad Londoño, ; Alejandro Daniel Velásquez Urzola,  . - 2006. Obra : Diabetes Research and Clinical Practice Idioma : Inglés (eng) Palabras clave : Type 1 diabetes  GADA  IA-2A  IAA  Colombia Resumen : We underwent a project aimed to define the clinical and immunological characteristics of type 1 diabetes (T1D) in a Colombian population. This was a multicenter and cross-sectional study. Patients were systematically interviewed and their medical records reviewed, using a questionnaire that sought information about demographic, clinical and immunological characteristics. Glutamic acid decarboxylase antibodies (GADA), tyrosine phosphatase antibodies (IA-2A) and insulin antibodies (IAA) were examined by radioimmunoassay. There were 107 patients with T1D. Male:female ratio was 1:1. Half of the patients developed diabetes ketoacidosis at onset. GADA, IA-2A, and IAA were detected in 45%, 40%, and 69% of the cases, respectively. GADA positive patients were older and had a less duration of disease than patients without these autoantibodies ( p  Mención de responsabilidad : G J Tobon, A Arango, V Abad, J García, H Cuervo, A Velásquez, I D Angel, P Vega, A Abad, J-M Anaya Referencia : Diabetes Res Clin Pract. 2006 May;72(2):170-5. DOI (Digital Object Identifier) : 10.1016/j.diabres.2005.10.016 PMID : 16325957 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0168822705004225 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4420

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Código de barras	Número de Ubicación	Tipo de medio	Ubicación	Sección	Estado
DD000920	AC-2006-018	Archivo digital	Producción Científica	Artículos científicos	Disponible