2 búsqueda de la palabra clave 'Action verbs'

Unspeakable motion: Selective action-verb impairments in Parkinson’s disease patients without mild cognitive impairment / Omar Fredy Buriticá Henao ; Leonardo Fabio Moreno Gómez  

Público ISBD Título : Unspeakable motion: Selective action-verb impairments in Parkinson’s disease patients without mild cognitive impairment Tipo de documento : documento electrónico Autores : Omar Fredy Buriticá Henao, ; Leonardo Fabio Moreno Gómez, Fecha de publicación : 2017 Títulos uniformes : Brain & Language Idioma : Inglés (eng) Palabras clave : Parkinson’s disease  Mild cognitive impairment  Picture naming  Action verbs  Manipulable nouns  Motor semantics Resumen : Parkinson's disease (PD) patients show marked impairments in processing action verbs, and to a lesser extent, concrete (specially, manipulable) nouns. However, it is still unclear to what extent deficits in each of these categories are influenced by more general cognitive dysfunctions, and whether they are modulated by the words' implied motility. To examine these issues, we evaluated 49 non-demented PD patients and 49 healthy volunteers in an oral production task. The patients were divided into two groups depending on the presence or absence of mild cognitive impairment (PD-MCI and PD-nMCI, respectively). Participants named pictures of actions varying in motion content (low and high) and of objects varying in manipulability (low and high). The PD-MCI group showed deficits across all four categories. However, PD-nMCI patients exhibited a selective difficulty for high-motion action verbs. This finding corroborates and refines previous results suggesting that disturbances of action-related lexico-semantic information in PD constitute a sui generis alteration manifested early in the course of the disease's physiopathology. Moreover, it suggests that the grounding of action verbs on motor circuits could depend on fine-grained intracategorical semantic distinctions. Mención de responsabilidad : Yamile Bocanegra, Adolfo M García, Francisco Lopera, David Pineda, Ana Baena, Paula Ospina, Diana Alzate, Omar Buriticá, Leonardo Moreno, Agustín Ibáñez, Fernando Cuetos Referencia : Brain Lang. 2017 May;168:37-46. DOI (Digital Object Identifier) : 10.1016/j.bandl.2017.01.005 PMID : 28131052 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0093934X16301262 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4038 Unspeakable motion: Selective action-verb impairments in Parkinson’s disease patients without mild cognitive impairment [documento electrónico] / Omar Fredy Buriticá Henao, ; Leonardo Fabio Moreno Gómez,  . - 2017. Obra : Brain & Language Idioma : Inglés (eng) Palabras clave : Parkinson’s disease  Mild cognitive impairment  Picture naming  Action verbs  Manipulable nouns  Motor semantics Resumen : Parkinson's disease (PD) patients show marked impairments in processing action verbs, and to a lesser extent, concrete (specially, manipulable) nouns. However, it is still unclear to what extent deficits in each of these categories are influenced by more general cognitive dysfunctions, and whether they are modulated by the words' implied motility. To examine these issues, we evaluated 49 non-demented PD patients and 49 healthy volunteers in an oral production task. The patients were divided into two groups depending on the presence or absence of mild cognitive impairment (PD-MCI and PD-nMCI, respectively). Participants named pictures of actions varying in motion content (low and high) and of objects varying in manipulability (low and high). The PD-MCI group showed deficits across all four categories. However, PD-nMCI patients exhibited a selective difficulty for high-motion action verbs. This finding corroborates and refines previous results suggesting that disturbances of action-related lexico-semantic information in PD constitute a sui generis alteration manifested early in the course of the disease's physiopathology. Moreover, it suggests that the grounding of action verbs on motor circuits could depend on fine-grained intracategorical semantic distinctions. Mención de responsabilidad : Yamile Bocanegra, Adolfo M García, Francisco Lopera, David Pineda, Ana Baena, Paula Ospina, Diana Alzate, Omar Buriticá, Leonardo Moreno, Agustín Ibáñez, Fernando Cuetos Referencia : Brain Lang. 2017 May;168:37-46. DOI (Digital Object Identifier) : 10.1016/j.bandl.2017.01.005 PMID : 28131052 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0093934X16301262 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4038

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Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences / Omar Fredy Buriticá Henao  

Público ISBD Título : Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences Tipo de documento : documento electrónico Autores : Omar Fredy Buriticá Henao, Fecha de publicación : 2015 Títulos uniformes : Cortex Idioma : Inglés (eng) Palabras clave : Parkinson's disease  syntax  action verbs  action semantics  object semantics  executive functions  mild cognitive impairment Resumen : Several studies have recently shown that basal ganglia (BG) deterioration leads to distinctive impairments in the domains of syntax, action verbs, and action semantics. In particular, such disruptions have been repeatedly observed in Parkinson's disease (PD) patients. However, it remains unclear whether these deficits are language-specific and whether they are equally dissociable from other reported disturbances –viz., processing of object semantics. To address these issues, we administered linguistic, semantic, and executive function (EFs) tasks to two groups of non-demented PD patients, with and without mild cognitive impairment (PD-MCI and PD-nMCI, respectively). We compared these two groups with each other and with matched samples of healthy controls. Our results showed that PD patients exhibited linguistic and semantic deficits even in the absence of MCI. However, not all domains were equally related to EFs and MCI across samples. Whereas EFs predicted disturbances of syntax and object semantics in both PD-nMCI and PD-MCI, they had no impact on action-verb and action-semantic impairments in either group. Critically, patients showed disruptions of action-verb production and action semantics in the absence of MCI and without any executive influence, suggesting a sui generis deficit present since early stages of the disease. These findings indicate that varied language domains are differentially related to the BG, contradicting popular approaches to neurolinguistics. Mención de responsabilidad : Yamile Bocanegra, Adolfo M García, David Pineda, Omar Buriticá, Andrés Villegas, Francisco Lopera, Diana Gómez, Catalina Gómez-Arias, Juan F Cardona, Natalia Trujillo, Agustín Ibáñez Referencia : Cortex. 2015 Aug;69:237-54. DOI (Digital Object Identifier) : 10.1016/j.cortex.2015.05.022 PMID : 26103601 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0010945215001811#abs0010 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3895 Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences [documento electrónico] / Omar Fredy Buriticá Henao,  . - 2015. Obra : Cortex Idioma : Inglés (eng) Palabras clave : Parkinson's disease  syntax  action verbs  action semantics  object semantics  executive functions  mild cognitive impairment Resumen : Several studies have recently shown that basal ganglia (BG) deterioration leads to distinctive impairments in the domains of syntax, action verbs, and action semantics. In particular, such disruptions have been repeatedly observed in Parkinson's disease (PD) patients. However, it remains unclear whether these deficits are language-specific and whether they are equally dissociable from other reported disturbances –viz., processing of object semantics. To address these issues, we administered linguistic, semantic, and executive function (EFs) tasks to two groups of non-demented PD patients, with and without mild cognitive impairment (PD-MCI and PD-nMCI, respectively). We compared these two groups with each other and with matched samples of healthy controls. Our results showed that PD patients exhibited linguistic and semantic deficits even in the absence of MCI. However, not all domains were equally related to EFs and MCI across samples. Whereas EFs predicted disturbances of syntax and object semantics in both PD-nMCI and PD-MCI, they had no impact on action-verb and action-semantic impairments in either group. Critically, patients showed disruptions of action-verb production and action semantics in the absence of MCI and without any executive influence, suggesting a sui generis deficit present since early stages of the disease. These findings indicate that varied language domains are differentially related to the BG, contradicting popular approaches to neurolinguistics. Mención de responsabilidad : Yamile Bocanegra, Adolfo M García, David Pineda, Omar Buriticá, Andrés Villegas, Francisco Lopera, Diana Gómez, Catalina Gómez-Arias, Juan F Cardona, Natalia Trujillo, Agustín Ibáñez Referencia : Cortex. 2015 Aug;69:237-54. DOI (Digital Object Identifier) : 10.1016/j.cortex.2015.05.022 PMID : 26103601 En línea : https://linkinghub.elsevier.com/retrieve/pii/S0010945215001811#abs0010 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3895

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