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Time of Cold Ischemia and Delayed Graft Function in a Cohort of Renal Transplant Patients in a Reference Center / John Fredy Nieto Ríos ; Catalina Ocampo Kohn ; Carolina Lucía Ochoa García ; Arbey Aristizabal Álzate ; Gustavo Adolfo Zuluaga Valencia    

Público ISBD Título : Time of Cold Ischemia and Delayed Graft Function in a Cohort of Renal Transplant Patients in a Reference Center Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Carolina Lucía Ochoa García, ; Arbey Aristizabal Álzate, ; Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2019 Títulos uniformes : Indian Journal of Nephrology Idioma : Inglés (eng) Palabras clave : Acute rejection  cold ischemia time  delayed graft function  graft loss  immunosuppression  kidney transplantation Resumen : There are many factors involved in the delayed graft function of a renal graft, with prolonged cold ischemia time being one of the most relevant. The aim of this study is to evaluate the relationship between the time of cold ischemia and the delayed graft function, and acute rejection and graft loss at 1 year of follow-up. A retrospective cohort of 347 renal transplant patients were evaluated during the years 2009-2013. The incidence of delayed graft function was 18.4% (n = 65). The cold ischemia time was an independent risk factor for delayed graft function (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.04-1.16). By grouping the time of cold ischemia by intervals, the risk of delayed graft function was greater in the 12-18 hours group (OR 2.06, 95% CI 1.02-4.15) and in the >18 hours group (OR 3.38, 95% CI 1.57-7.27). The risk of acute rejection did not increase with longer cold ischemia (p = 0.69), and cold ischemia time was not a risk factor for renal graft loss at 1-year follow-up (hazard ratio 0.97, 95% CI 0.88-1.06). In conclusion the time of cold ischemia (>12 hours) in renal transplant recipients of optimal deceased donors increases the risk of delayed graft function; however, this does not negatively impact the results in acute rejection or graft loss in the first year of the transplant. Mención de responsabilidad : J F Nieto-Ríos, C L Ochoa-García, A Serna-Campuzano, B Benavides-Hermosa, L L Calderón-Puentes, A Aristizabal-Alzate, C Ocampo-Kohn, G Zuluaga-Valencia, L M Serna-Higuita Referencia : Indian J Nephrol. 2019 Jan-Feb;29(1):8-14. DOI (Digital Object Identifier) : 10.4103/ijn.IJN_162_18 PMID : 30814787 Derechos de uso : CC BY-NC-SA En línea : http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2019;volume=29;iss [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4259 Time of Cold Ischemia and Delayed Graft Function in a Cohort of Renal Transplant Patients in a Reference Center [documento electrónico] / John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Carolina Lucía Ochoa García, ; Arbey Aristizabal Álzate, ; Gustavo Adolfo Zuluaga Valencia,  . - 2019. Obra : Indian Journal of Nephrology Idioma : Inglés (eng) Palabras clave : Acute rejection  cold ischemia time  delayed graft function  graft loss  immunosuppression  kidney transplantation Resumen : There are many factors involved in the delayed graft function of a renal graft, with prolonged cold ischemia time being one of the most relevant. The aim of this study is to evaluate the relationship between the time of cold ischemia and the delayed graft function, and acute rejection and graft loss at 1 year of follow-up. A retrospective cohort of 347 renal transplant patients were evaluated during the years 2009-2013. The incidence of delayed graft function was 18.4% (n = 65). The cold ischemia time was an independent risk factor for delayed graft function (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.04-1.16). By grouping the time of cold ischemia by intervals, the risk of delayed graft function was greater in the 12-18 hours group (OR 2.06, 95% CI 1.02-4.15) and in the >18 hours group (OR 3.38, 95% CI 1.57-7.27). The risk of acute rejection did not increase with longer cold ischemia (p = 0.69), and cold ischemia time was not a risk factor for renal graft loss at 1-year follow-up (hazard ratio 0.97, 95% CI 0.88-1.06). In conclusion the time of cold ischemia (>12 hours) in renal transplant recipients of optimal deceased donors increases the risk of delayed graft function; however, this does not negatively impact the results in acute rejection or graft loss in the first year of the transplant. Mención de responsabilidad : J F Nieto-Ríos, C L Ochoa-García, A Serna-Campuzano, B Benavides-Hermosa, L L Calderón-Puentes, A Aristizabal-Alzate, C Ocampo-Kohn, G Zuluaga-Valencia, L M Serna-Higuita Referencia : Indian J Nephrol. 2019 Jan-Feb;29(1):8-14. DOI (Digital Object Identifier) : 10.4103/ijn.IJN_162_18 PMID : 30814787 Derechos de uso : CC BY-NC-SA En línea : http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2019;volume=29;iss [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4259

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Código de barras	Número de Ubicación	Tipo de medio	Ubicación	Sección	Estado
DD001238	AC-2019-027	Archivo digital	Producción Científica	Artículos científicos	Disponible

Documentos electrónicos

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Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient / John Fredy Nieto Ríos ; Catalina Ocampo Kohn ; Arbey Aristizabal Álzate ; Lina Maria Serna Higuita ; Isabel Cristina Ramírez Sánchez ; Gustavo Adolfo Zuluaga Valencia    

Público ISBD Título : Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Arbey Aristizabal Álzate, ; Lina Maria Serna Higuita, ; Isabel Cristina Ramírez Sánchez, ; Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2014 Títulos uniformes : Nefrología Idioma : Inglés (eng) Palabras clave : Mucormycosis rhino-orbital-cerebral  kidney transplantation  acute rejection  immunosuppression Resumen : Rhino-orbital-cerebral mucormycosis is a potentially fatal mycotic infection in immunosuppressed patients. The main risk factors for acquiring this infection are poorly controlled diabetes mellitus, iron overload, potent immunosuppression and chronic steroid use. In this review, we present the case of a kidney transplant patient who, after treatment of an acute rejection episode with high doses of steroids and potent immunosuppression with tacrolimus and mycophenolate, presented with rapidly progressing rhino-orbital-cerebral mucormycosis that required aggressive surgical treatment, immunosuppression discontinuation and potent antifungal treatment. Mención de responsabilidad : John F Nieto-Ríos, Luis F Moreno-Coral, Andrés Zapata-Cárdenas, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Lina M Serna-Higuita, Isabel C Ramírez-Sánchez, Gustavo A Zuluaga-Valencia Referencia : Nefrologia. 2014;34(1):120-4. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2013.Nov.12084 PMID : 24463869 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/en-successful-treatment-rhino-orbital-cerebral [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3771 Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient [documento electrónico] / John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Arbey Aristizabal Álzate, ; Lina Maria Serna Higuita, ; Isabel Cristina Ramírez Sánchez, ; Gustavo Adolfo Zuluaga Valencia,  . - 2014. Obra : Nefrología Idioma : Inglés (eng) Palabras clave : Mucormycosis rhino-orbital-cerebral  kidney transplantation  acute rejection  immunosuppression Resumen : Rhino-orbital-cerebral mucormycosis is a potentially fatal mycotic infection in immunosuppressed patients. The main risk factors for acquiring this infection are poorly controlled diabetes mellitus, iron overload, potent immunosuppression and chronic steroid use. In this review, we present the case of a kidney transplant patient who, after treatment of an acute rejection episode with high doses of steroids and potent immunosuppression with tacrolimus and mycophenolate, presented with rapidly progressing rhino-orbital-cerebral mucormycosis that required aggressive surgical treatment, immunosuppression discontinuation and potent antifungal treatment. Mención de responsabilidad : John F Nieto-Ríos, Luis F Moreno-Coral, Andrés Zapata-Cárdenas, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Lina M Serna-Higuita, Isabel C Ramírez-Sánchez, Gustavo A Zuluaga-Valencia Referencia : Nefrologia. 2014;34(1):120-4. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2013.Nov.12084 PMID : 24463869 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/en-successful-treatment-rhino-orbital-cerebral [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3771

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Código de barras	Número de Ubicación	Tipo de medio	Ubicación	Sección	Estado
DD000346	AC-2014-012	Archivo digital	Producción Científica	Artículos científicos	Disponible

Documentos electrónicos

2014-012.pdf Adobe Acrobat PDF