2 búsqueda de la palabra clave 'Autophagy'

Autophagy in endocrine tumors / Luis Vicente Syro Moreno  

Público ISBD Título : Autophagy in endocrine tumors Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2015 Títulos uniformes : Endocrine Related Cancer Idioma : Inglés (eng) Palabras clave : Autophagy  autophagy modulation  endocrine disease  neoplasia  therapeutic potential Resumen : Autophagy is an important intracellular process involving the degradation of cytoplasmic components. It is involved in both physiological and pathological conditions, including cancer. The role of autophagy in cancer is described as a ‘double-edged sword,’ a term that reflects its known participation in tumor suppression, tumor survival and tumor cell proliferation. Available research regarding autophagy in endocrine cancer supports this concept. Autophagy shows promise as a novel therapeutic target in different types of endocrine cancer, inhibiting or increasing treatment efficacy in a context- and cell-type dependent manner. At present, however, there is very little research concerning autophagy in endocrine tumors. No research was reported connecting autophagy to some of the tumors of the endocrine glands such as the pancreas and ovary. This review aims to elucidate the roles of autophagy in different types of endocrine cancer and highlight the need for increased research in the field. Mención de responsabilidad : Andrea Weckman, Fabio Rotondo, Antonio Di Ieva, Luis V Syro, Henriett Butz, Michael D Cusimano and Kalman Kovacs Referencia : Endoc Rel Cancer. 2015;22(4):205-18. DOI (Digital Object Identifier) : 10.1530/ERC-15-0042 En línea : https://erc.bioscientifica.com/view/journals/erc/22/4/R205.xml Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3901 Autophagy in endocrine tumors [documento electrónico] / Luis Vicente Syro Moreno,  . - 2015. Obra : Endocrine Related Cancer Idioma : Inglés (eng) Palabras clave : Autophagy  autophagy modulation  endocrine disease  neoplasia  therapeutic potential Resumen : Autophagy is an important intracellular process involving the degradation of cytoplasmic components. It is involved in both physiological and pathological conditions, including cancer. The role of autophagy in cancer is described as a ‘double-edged sword,’ a term that reflects its known participation in tumor suppression, tumor survival and tumor cell proliferation. Available research regarding autophagy in endocrine cancer supports this concept. Autophagy shows promise as a novel therapeutic target in different types of endocrine cancer, inhibiting or increasing treatment efficacy in a context- and cell-type dependent manner. At present, however, there is very little research concerning autophagy in endocrine tumors. No research was reported connecting autophagy to some of the tumors of the endocrine glands such as the pancreas and ovary. This review aims to elucidate the roles of autophagy in different types of endocrine cancer and highlight the need for increased research in the field. Mención de responsabilidad : Andrea Weckman, Fabio Rotondo, Antonio Di Ieva, Luis V Syro, Henriett Butz, Michael D Cusimano and Kalman Kovacs Referencia : Endoc Rel Cancer. 2015;22(4):205-18. DOI (Digital Object Identifier) : 10.1530/ERC-15-0042 En línea : https://erc.bioscientifica.com/view/journals/erc/22/4/R205.xml Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3901

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Código de barras	Número de Ubicación	Tipo de medio	Ubicación	Sección	Estado
DD000481	AC-2015-034	Archivo digital	Producción Científica	Artículos científicos	Disponible

Autophagy in the endocrine glands / Luis Vicente Syro Moreno  

Público ISBD Título : Autophagy in the endocrine glands Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2014 Títulos uniformes : Journal of Molecular Endocrinology Idioma : Inglés (eng) Palabras clave : Autophagy  endocrine glands  crinophagy  endocrine diseases Resumen : Autophagy is an important cellular process involving the degradation of intracellular components. Its regulation is complex and while there are many methods available, there is currently no single effective way of detecting and monitoring autophagy. It has several cellular functions that are conserved throughout the body, as well as a variety of different physiological roles depending on the context of its occurrence in the body. Autophagy is also involved in the pathology of a wide range of diseases. Within the endocrine system, autophagy has both its traditional conserved functions and specific functions. In the endocrine glands, autophagy plays a critical role in controlling intracellular hormone levels. In peptide-secreting cells of glands such as the pituitary gland, crinophagy, a specific form of autophagy, targets the secretory granules to control the levels of stored hormone. In steroid-secreting cells of glands such as the testes and adrenal gland, autophagy targets the steroid-producing organelles. The dysregulation of autophagy in the endocrine glands leads to several different endocrine diseases such as diabetes and infertility. This review aims to clarify the known roles of autophagy in the physiology of the endocrine system, as well as in various endocrine diseases. Mención de responsabilidad : Andrea Weckman, Antonio Di Ieva, Fabio Rotondo, Luis V Syro, Leon D Ortiz, Kalman Kovacs and Michael D Cusimano Referencia : Jour of Mol Endocrin. 2014;52(2):151-63. DOI (Digital Object Identifier) : 10.1530/JME-13-0241 En línea : https://jme.bioscientifica.com/view/journals/jme/52/2/R151.xml Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3794 Autophagy in the endocrine glands [documento electrónico] / Luis Vicente Syro Moreno,  . - 2014. Obra : Journal of Molecular Endocrinology Idioma : Inglés (eng) Palabras clave : Autophagy  endocrine glands  crinophagy  endocrine diseases Resumen : Autophagy is an important cellular process involving the degradation of intracellular components. Its regulation is complex and while there are many methods available, there is currently no single effective way of detecting and monitoring autophagy. It has several cellular functions that are conserved throughout the body, as well as a variety of different physiological roles depending on the context of its occurrence in the body. Autophagy is also involved in the pathology of a wide range of diseases. Within the endocrine system, autophagy has both its traditional conserved functions and specific functions. In the endocrine glands, autophagy plays a critical role in controlling intracellular hormone levels. In peptide-secreting cells of glands such as the pituitary gland, crinophagy, a specific form of autophagy, targets the secretory granules to control the levels of stored hormone. In steroid-secreting cells of glands such as the testes and adrenal gland, autophagy targets the steroid-producing organelles. The dysregulation of autophagy in the endocrine glands leads to several different endocrine diseases such as diabetes and infertility. This review aims to clarify the known roles of autophagy in the physiology of the endocrine system, as well as in various endocrine diseases. Mención de responsabilidad : Andrea Weckman, Antonio Di Ieva, Fabio Rotondo, Luis V Syro, Leon D Ortiz, Kalman Kovacs and Michael D Cusimano Referencia : Jour of Mol Endocrin. 2014;52(2):151-63. DOI (Digital Object Identifier) : 10.1530/JME-13-0241 En línea : https://jme.bioscientifica.com/view/journals/jme/52/2/R151.xml Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3794

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Código de barras	Número de Ubicación	Tipo de medio	Ubicación	Sección	Estado
DD000369	AC-2014-035	Archivo digital	Producción Científica	Artículos científicos	Disponible